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Procedure: PET Scan

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Total 4670 results found since Jan 2013.

SARS-CoV-2 egress from Vero cells: a morphological approach
This study aimed to shed light on the morphological features of SARS-CoV-2 egress by utilizing transmission and high-resolution scanning electron microscopy, along with serial electron tomography, to describe the route of nascent virions towards the extracellular medium. Electron microscopy revealed that the clusters of viruses in the paracellular space did not seem to result from collective virus release. Instead, virus accumulation was observed on incurved areas of the cell surface, with egress primarily occurring through individual vesicles. Additionally, our findings showed that the emission of long membrane projection...
Source: Histochemistry and Cell Biology - September 22, 2023 Category: Biomedical Science Source Type: research

Critical care, maternal and neonatal outcomes of pregnant women with COVID ‐19 admitted to eight intensive care units during the wildtype, alpha and delta waves of the pandemic across the North West of England—a retrospective review
ConclusionsOf the women admitted to ICU antepartum, 40% were discharged while remaining pregnant and 60% had expedited delivery. Antepartum women who were discharged from ICU without giving birth may receive lower rates of mechanical ventilation than those who delivered in ICU or admitted postpartum; however, further studies are needed to confirm or refute this association.
Source: Acta Obstetricia et Gynecologica Scandinavica - September 21, 2023 Category: OBGYN Authors: Kailash Bhatia, Malachy Columb, Bhaskar Narayan, Anthony Wilson, Group of Obstetric Anesthetists of Lancashire; Greater Manchester and Mersey (GOAL ‐GM) Study Collaborators, A. Babits, R. Downes, J. Lie, S. Leach, O. Froud, A Sawyerr, J Desai Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Does translocal vulnerability apply to labor migrants into the sesame production belt amid covid-19? Evidence from districts in Ethiopia
This study tries to connect the current spread of covid-19 with the translocal vulnerability context. Primarily, it empirically argued the translocal vulnerability factor is the main determinant for the farm households to send families’ labor as a livelihood diversification strategy. Very limited studies consider the translocal vulnerability implication of migration; notably to the best of the researchers’ knowledge, studies that linked covid-19 with translocal vulnerability context are scant. On top of that, many studies that link migration with covid-19 tend to be inclined to international migration with very limited...
Source: International Journal of Migration, Health and Social Care - September 14, 2023 Category: International Medicine & Public Health Authors: Kibrom Adino Abate Tegegne Derbe Libshwork Linger Ayele Mersha Source Type: research

Suramin inhibits SARS-CoV-2 nucleocapsid phosphoprotein genome packaging function
Virus Res. 2023 Sep 11:199221. doi: 10.1016/j.virusres.2023.199221. Online ahead of print.ABSTRACTThe coronavirus disease 2019 (COVID-19) pandemic is fading, however its etiologic agent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues posing - despite the availability of licensed vaccines - a global health threat, due to the potential emergence of vaccine-resistant SARS-CoV-2 variants. This makes the development of new drugs against COVID-19 a persistent urgency and sets as research priority the validation of novel therapeutic targets within the SARS-CoV-2 proteome. Among these, a promising one is the...
Source: Virus Research - September 13, 2023 Category: Virology Authors: Irene Boniardi Angela Corona Jerome Basquin Claire Basquin Jessica Milia Istv án Nagy Enzo Tramontano Luca Zinzula Source Type: research

Preliminary PET imaging of 11Cevobrutinib in mouse models of colorectal cancer, SARS ‐CoV‐2, and lung damage: Radiosynthesis via base‐aided palladium‐NiXantphos‐mediated 11C‐carbonylation
In conclusion, [11C]evobrutinib was successfully synthesized by11C-carbonylation and based on our preliminary studies does not appear to be a promising BTK-targeted PET radiotracer in the rodent disease models studied herein.
Source: Journal of Labelled Compounds and Radiopharmaceuticals - September 11, 2023 Category: Biochemistry Authors: Amanda J. Boyle, Anton Lindberg, Junchao Tong, Dongxu Zhai, Fang Liu, Neil Vasdev Tags: RESEARCH ARTICLE Source Type: research

Percutaneous cholecystostomy in the management of acute cholecystitis-comparative analysis of before and after the COVID 19 pandemic
CONCLUSION: PC is an effective and safe treatment method that reduced the operating room and intensive care burden during the exacerbation of the COVID 19 pandemic. Therefore, it seems like a logical option to expand the PC indications at times when the number of COVID 19 patients increases.PMID:37681720 | DOI:10.14744/tjtes.2023.22901
Source: Turkish Journal of Trauma and Emergency Surgery : TJTES - September 8, 2023 Category: Emergency Medicine Authors: Fatih K ılınç Çağlayan Çakır Ömer Yıldız Alpen Yahya G ümüşoğlu Abd ülcelil Gezmiş Fidan Ayg ün Source Type: research