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Viruses, Vol. 15, Pages 1933: Unraveling the Dynamics of Omicron (BA.1, BA.2, and BA.5) Waves and Emergence of the Deltacton Variant: Genomic Epidemiology of the SARS-CoV-2 Epidemic in Cyprus (Oct 2021 & ndash;Oct 2022)
This study offers a comprehensive assessment spanning genetic, phylogenetic, phylodynamic, and phylogeographic dimensions, focused on the trajectory of the SARS-CoV-2 epidemic in Cyprus. Based on a dataset comprising 4700 viral genomic sequences obtained from affected individuals between October 2021 and October 2022, our analysis is presented. Over this timeframe, a total of 167 distinct lineages and sublineages emerged, including variants such as Delta and Omicron (1, 2, and 5). Notably, during the fifth wave of infections, Omicron subvariants 1 and 2 gained prominence, followed by the ascendancy of Omicron 5 in the subs...
Source: Viruses - September 15, 2023 Category: Virology Authors: Andreas C. Chrysostomou Bram Vrancken Christos Haralambous Maria Alexandrou Ioanna Gregoriou Marios Ioannides Costakis Ioannou Olga Kalakouta Christos Karagiannis Markella Marcou Christina Masia Michail Mendris Panagiotis Papastergiou Philippos C. Patsali Tags: Article Source Type: research
The IMPACT of the COVID-19 Pandemic on Prescription Drug Use in Patients with Psoriasis Vulgaris in Germany
ConclusionThroughout the COVID-19 pandemic the PSO indicated medication sales increased for first-line biological and second-line treatment. This shows that despite the pandemic impact, there continues to be an increase in sales volume for biologics. Only German federal states with intermittently very high COVID-19 incidences show a stagnation in sales volume. The reasons for this need to be investigated in further studies to possibly gain a better understanding of the concerns and uncertainties of patients with PSO.
Source: Dermatology and Therapy - September 14, 2023 Category: Dermatology Source Type: research
Rapid point-of-care detection of SARS-CoV-2 infection in exhaled breath using ion mobility spectrometry: a pilot study
ConclusionsDespite identifying several peaks by MCC-IMS with significant differences in peak intensity between PCR-negative and PCR-positive samples, finding a classification system that allows reliable differentiation between the two groups proved to be difficult. However, with some modifications to the setup, breath gas analysis using MCC-IMS may be a useful diagnostic toolbox for SARS-CoV-2 infection.Trial registration: This study was registered at ClinicalTrials.gov on September 21, 2020 (NCT04556318; Study-ID: HC-N-H-2004).
Source: European Journal of Medical Research - September 2, 2023 Category: Research Source Type: research
Old foes following news ways? —Pandemic-related changes in the epidemiology of viral respiratory tract infections
ConclusionCompared to pre-pandemic years, we observed a dramatic increase in pediatric RTIs with an incrementing spectrum of viruses and a predominance in Rhino/Enterovirus infections – leading to a high rate of hospital admissions, particularly in conjunction with other viruses. This caused an acute shortage in medical care and may also be followed by an increase of virus-triggered secondary chronic respiratory diseases like asthma—rendering a burden on the health system.
Source: Infection - August 29, 2023 Category: Infectious Diseases Source Type: research
NVX-CoV2373-induced T- and B-cellular immunity in immunosuppressed people with multiple sclerosis that failed to respond to mRNA and viral vector SARS-CoV-2 vaccines
ConclusionsVaccination with two doses of NVX-CoV2373 was able to elicit a SARS-CoV-2-specific immune response in pwMS lacking adequate immune responses to previous mRNA/viral vector vaccination. For patients receiving S1PR modulators, an increase in anti-SARS-CoV-2 IgG antibodies was detected after NVX-CoV2373 vaccination, whereas in ocrelizumab-treated patients, the increase of antiviral T-cell responses was more pronounced. Our data may impact clinical decision-making by influencing the preference for NVX-CoV2373 vaccination in pwMS receiving treatment with S1PR modulation or anti-CD20 treatment.
Source: Frontiers in Immunology - July 20, 2023 Category: Allergy & Immunology Source Type: research
Health of homeless individuals during the COVID-19 pandemic
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2023 Jul 19. doi: 10.1007/s00103-023-03739-8. Online ahead of print.ABSTRACTThe living situation and health of homeless people differs from the general population in many ways. It is reasonable to assume that the homeless population has been particularly vulnerable during the coronavirus disease 2019 (COVID-19) pandemic. This narrative review will summarize the current literature on the health and care of homeless people during the COVID-19 pandemic. The literature research was performed between December 2022 and February 2023. In addition to the current nation...
Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - July 19, 2023 Category: International Medicine & Public Health Authors: Victoria van R üth Andr é Hajek Fabian Heinrich Benjamin Ondruschka Klaus P üschel Franziska Bertram Source Type: research
Life Satisfaction During the COVID-19 Pandemic: The Role of Human, Economic, Social, and Psychological Capital
AbstractA cornerstone of well-being research is that the resource-rich are happier with their lives than the resource-poor and better positioned to cope with stressful life events. This paper addresses the role of various resources —human, economic, social, and psychological capital—in life satisfaction during the coronavirus pandemic, using panel data from Germany and the United Kingdom for 2020 and 2021. Cross-sectionally, we find life satisfaction to be clearly related to all these forms of capital, with psychological c apital being the strongest predictor of life satisfaction. Longitudinally, the capital endowments...
Source: Journal of Happiness Studies - July 18, 2023 Category: Psychiatry & Psychology Source Type: research
Analysis of acute COVID-19 including chronic morbidity: protocol for the deep phenotyping National Pandemic Cohort Network in Germany (NAPKON-HAP)
ConclusionNAPKON-HAP establishes a platform with standardized high-resolution data and biospecimen collection of hospitalized COVID-19 patients of different disease severities in Germany. With this study, we will add significant scientific insights and provide high-quality data to aid researchers to investigate COVID-19 pathophysiology, pathology, and chronic morbidity.
Source: Infection - July 11, 2023 Category: Infectious Diseases Source Type: research
Effect of phthalocyanine oral and nasal antiseptic solutions on the infectivity of SARS-CoV-2 in patients with COVID-19: a randomized controlled trial
CONCLUSIONS: Use of phthalocyanine mouthwash and nasal spray is effective at reducing SARS-CoV-2 infectivity.PMID:37426884 | PMC:PMC10326526 | DOI:10.3205/000321
Source: GMS German Medical Science - July 10, 2023 Category: General Medicine Authors: Andr éa Name Colado Simão Nicole Perugini Stadtlober Audrey Alesandra Stinghen Garcia Lonni Luiza Mara Ven âncio Guilherme Lerner Trigo Pedro Luis Candido de Souza Cassela Thais Mastellini Sanches Silva Maria De F átima Oliveira Hirth Ruiz Marcell Aly Source Type: research
