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Total 19535 results found since Jan 2013.

Attitudes and Perceptions on Advance Care Planning Among Chinese-Speaking Older Australians
CONCLUSION: Healthcare professionals should initiate ACP discussion using culturally appropriate communication with consideration of personal values, past experiences and family dynamics. Efforts should be invested in raising public awareness of ACP within the Chinese-Australian community.PMID:37658638 | DOI:10.1177/10499091231200366
Source: The American Journal of Hospice and Palliative Care - September 2, 2023 Category: Palliative Care Authors: Ling H Yeoh Benjamin Tan Joel Rhee Craig Sinclair Source Type: research

Culture of primary human meibomian gland cells from surgically excised eyelid tissue
Exp Eye Res. 2023 Aug 30:109636. doi: 10.1016/j.exer.2023.109636. Online ahead of print.ABSTRACTMeibomian gland dysfunction is one of the most common ocular diseases, with therapeutic treatment being primarily palliative due to our incomplete understanding of meibomian gland (MG) pathophysiology. To progress in vitro studies of human MG, this study describes a comprehensive protocol, with detailed troubleshooting, for the successful isolation, cultivation and cryopreservation of primary MG cells using biopsy-size segments of human eyelid tissue that would otherwise be discarded during surgery. MG acini were isolated and us...
Source: Cell Research - September 1, 2023 Category: Cytology Authors: Ha T Duong Minh Anh Thu Phan Michele C Madigan Fiona Stapleton Geoffrey Wilcsek Mark Willcox Blanka Golebiowski Source Type: research

The Diagnosis and Treatment of Ampullary Carcinoma
CONCLUSION: The current state of the evidence on the treatment of ampullary carcinoma is poor. Therapeutic decisions should be discussed in an interdisciplinary tumor board and should, in our opinion, take the histological subtype into account.PMID:37656482 | DOI:10.3238/arztebl.m2023.0195
Source: Deutsches Arzteblatt International - September 1, 2023 Category: General Medicine Authors: Dirk Walter Andreas A Schnitzbauer Falko Schulze J örg Trojan Source Type: research

Clinical Impact of Radical Resection of Synchronous and Metachronous Peritoneal Metastases from Colorectal Cancer
CONCLUSIONS: Patients with radical resection of PM had good survival compared with those with chemotherapy alone, especially for metachronous PM. Surgical intervention should be considered for isolated metachronous PM when radical resection is feasible.PMID:37658266 | DOI:10.1245/s10434-023-14191-y
Source: Ann Oncol - September 1, 2023 Category: Cancer & Oncology Authors: Aina Kunitomo Akira Ouchi Koji Komori Takashi Kinoshita Yusuke Sato Tetsuya Abe Seiji Ito Tsuyoshi Sano Yasuhiro Shimizu Source Type: research

Who are the vulnerable lung cancer patients at risk for not receiving first-line curative or palliative treatment?
CONCLUSIONS: Several factors are associated with not receiving guideline-recommended NSCLC treatment with age, performance status, comorbidity and stage being most predictive of no treatment receipt. Efforts should be made to develop support for vulnerable lung cancer patients to improve adherence to optimal first-line therapy.PMID:37656828 | DOI:10.1080/0284186X.2023.2252581
Source: Acta Oncologica - September 1, 2023 Category: Cancer & Oncology Authors: Rikke Langballe Jakobsen Erik Iachina Maria Karlsen Randi Valbj ørn Ehlers Jeanette Haar Svendsen Mads Nordahl Bodtger Uffe Hilberg Ole Dalton Susanne Oksbjerg Bidstrup Pernille Envold Source Type: research

Pelvic insufficiency fractures and pelvic bone metastases after neoadjuvant (chemo)radiotherapy for rectal cancer
Conclusion: PIFs are a relatively common late complication of neoadjuvant (C)RT for rectal cancer but are often missed or misdiagnosed as pelvic bone metastases. The differentiation of PIFs from pelvic bone metastases is important because of a different treatment and disease outcome.PMID:37656773 | DOI:10.1080/0284186X.2023.2252168
Source: Acta Oncologica - September 1, 2023 Category: Cancer & Oncology Authors: Lotte Rijpma-Jacobs Ellen van der Vlies David B Meek Thomas L Bollen Peter D Siersema Bas L A M Weusten Martijn Intven Niels van Lelyveld Maartje Los Source Type: research

Comparison of home-based palliative care delivered by community health workers versus usual care: research protocol for a pilot randomized controlled trial
DISCUSSION: Pal-Care is a RCT funded by the NCI to explore utilization of CHWs to deliver a home-based palliative care intervention built upon the WHO Palliative Care toolkit (PCT), as compared to a usual care control group. The long-term goal of this research is to develop an effective and sustainable model for delivering home-based palliative care for cancer patients in underserved areas.TRIAL REGISTRATION (TRN): ClinicalTrials.gov ID# NCT04972630.PMID:37658397 | DOI:10.1186/s12904-023-01235-z
Source: Cancer Control - September 1, 2023 Category: Cancer & Oncology Authors: Suparna Qanungo Kathleen B Cartmell Martina Mueller Melissa Butcher Saswati Sarkar Tyler-Gail Carlson Mohan Madisetti Gaurav Kumar Source Type: research

Comparing effectiveness and safety of paclitaxel plus raltitrexed vs. paclitaxel alone in second-line palliative chemotherapy for metastatic gastric adenocarcinoma: A randomized phase II clinical trial
CONCLUSIONS: Second-line palliative chemotherapy with RP was shown to prolong the PFS and OS, especially among patients with ascites or peritoneal involvement, which warrants confirmation using larger sample studies.PMID:37653589 | DOI:10.20892/j.issn.2095-3941.2023.0112
Source: Cancer Control - September 1, 2023 Category: Cancer & Oncology Authors: Xiaoying Zhao Zhiyu Chen Xiaowei Zhang Xiaodong Zhu Wen Zhang Lixin Qiu Chenchen Wang Mingzhu Huang Zhe Zhang Wenhua Li Lei Yang Weijian Guo Source Type: research

Culture of primary human meibomian gland cells from surgically excised eyelid tissue
Exp Eye Res. 2023 Aug 30:109636. doi: 10.1016/j.exer.2023.109636. Online ahead of print.ABSTRACTMeibomian gland dysfunction is one of the most common ocular diseases, with therapeutic treatment being primarily palliative due to our incomplete understanding of meibomian gland (MG) pathophysiology. To progress in vitro studies of human MG, this study describes a comprehensive protocol, with detailed troubleshooting, for the successful isolation, cultivation and cryopreservation of primary MG cells using biopsy-size segments of human eyelid tissue that would otherwise be discarded during surgery. MG acini were isolated and us...
Source: Experimental Eye Research - September 1, 2023 Category: Opthalmology Authors: Ha T Duong Minh Anh Thu Phan Michele C Madigan Fiona Stapleton Geoffrey Wilcsek Mark Willcox Blanka Golebiowski Source Type: research

Adapting the Serious Illness Conversation Guide for Dementia Care
Conclusion: This paper presents the SICG-D, an adapted version of the SICG for use in dementia care. This guide leverages the strengths of the SICG to promote values-based ACP conversations and has been adapted to better facilitate patient-caregiver-clinician triadic communication.PMID:37655362 | DOI:10.1177/10499091231200214
Source: The American Journal of Hospice and Palliative Care - September 1, 2023 Category: Palliative Care Authors: Charlotte E Berry Sophie H Montgomery Robert Santulli Amelia Cullinan Source Type: research