Filtered By:
Specialty: Molecular Biology
This page shows you your search results in order of date. This is page number 13.
Order by Relevance | Date
Total 131552 results found since Jan 2013.
Response to the Letter to the Editor: Ethical Concerns of ChatGPT
Nucl Med Mol Imaging. 2023 Oct;57(5):215. doi: 10.1007/s13139-023-00819-0. Epub 2023 Aug 15.NO ABSTRACTPMID:37720880 | PMC:PMC10504132 | DOI:10.1007/s13139-023-00819-0
Source: Molecular Medicine - September 18, 2023 Category: Molecular Biology Authors: Hee-Seung Henry Bom Source Type: research
Interesting Presentation of Mycosis Fungoides in Staging on F-18 FDG PET/CT
We report an interesting case of mycosis fungoides with bilateral upper limb edema and share its findings on F-18 FDG PET/CT.PMID:37720879 | PMC:PMC10504174 | DOI:10.1007/s13139-023-00794-6
Source: Molecular Medicine - September 18, 2023 Category: Molecular Biology Authors: Deepanksha Datta Tanvi Sarwal Rajesh Kumar Sandeep Bairwa Vinay N Gowda Aasma Nalwa Source Type: research
Contribution of Metabolic Parameters and Pericolic Fat Stranding on Preoperative 18F-FDG PET/CT in Predicting Post-operative Histopathology and Outcome in Colorectal Cancer
CONCLUSION: Preoperative PET/CT contributes to CRC management by detecting additional metastases as well as predicting prognosis and postoperative findings such as T stage, N stage and tumor differentiation. The SUVmax may differentiate between T3 and T4 tumor. Reporting of pericolic fat stranding may contribute to the estimation of lymphatic invasion and positive surgical margin.PMID:37720878 | PMC:PMC10504194 | DOI:10.1007/s13139-023-00808-3
Source: Molecular Medicine - September 18, 2023 Category: Molecular Biology Authors: Selin Soyluoglu Busra Ozdemir Gunay Source Type: research
< sup > 68 < /sup > Ga-DOTANOC PET/CT for Screening and Surveillance of Von Hippel-Lindau (VHL) disease
CONCLUSION: Our results show that 68 Ga-DOTANOC PET/CT may be a useful modality for screening and follow-up of associated tumors in patients with germline gene mutation for VHL. It can be used as a one-stop imaging modality for VHL patients and may substitute for separate radiological investigations, making it more convenient for patients in terms of time and cost.PMID:37720877 | PMC:PMC10504222 | DOI:10.1007/s13139-023-00810-9
Source: Molecular Medicine - September 18, 2023 Category: Molecular Biology Authors: Shamim Ahmed Shamim Geetanjali Arora Naresh Kumar Jhangir Hussain Shreya Datta Gupta Arun Raj St Kritin Shankar Alpesh Goyal Rajesh Khadgawat Sambit Sagar Chandrasekhar Bal Source Type: research
Enantiomerization and enantioselective bioaccumulation of diclofop-methyl in tubifex worms
In this study, the hydrolysis of diclofop-methyl (DM) in aqueous system and the bioaccumulation of its main metabolite, Diclofop (DA), in the tubifex worms were investigated using enantioselective high-performance liquid chromatography. With the addition of tubifex, rapid hydrolysis was observed for DM. It is revealed that the hydrolysis of DM in the water and the accumulation of DA in the worms were both enantioselective. Meanwhile, either the hydrolysis amount or the levels of enantioselectivity were influenced by the tubifex. After incubated for 24 h, about 94.6% of the DM was hydrolyzed and the enantiomer fraction of m...
Source: Chirality - September 18, 2023 Category: Molecular Biology Authors: Tiantian Liu Xinhong Duan Source Type: research
Dual RNase activity of IRE1 as a target for anticancer therapies
J Cell Commun Signal. 2023 Sep 18. doi: 10.1007/s12079-023-00784-5. Online ahead of print.ABSTRACTThe unfolded protein response (UPR) is a cellular mechanism that protects cells during stress conditions in which there is an accumulation of misfolded proteins in the endoplasmic reticulum (ER). UPR activates three signaling pathways that function to alleviate stress conditions and promote cellular homeostasis and cell survival. During unmitigated stress conditions, however, UPR activation signaling changes to promote cell death through apoptosis. Interestingly, cancer cells take advantage of this pathway to facilitate surviv...
Source: Journal of Cell Communication and Signaling - September 18, 2023 Category: Molecular Biology Authors: Sylwia Bartoszewska Jakub S ławski James F Collawn Rafa ł Bartoszewski Source Type: research
S100a9 inhibits Atg9a transcription and participates in suppression of autophagy in cardiomyocytes induced by β < sub > 1 < /sub > -adrenoceptor autoantibodies
CONCLUSION: Our research showed that β1-AAs increased S100a9 expression in cardiomyocytes and that S100a9 interacted with HIF-1α, which prevented HIF-1α from entering the nucleus normally, thus inhibiting the transcription of Atg9a. This resulted in autophagy inhibition and cardiac dysfunction.PMID:37723445 | PMC:PMC10506287 | DOI:10.1186/s11658-023-00486-1
Source: Mol Biol Cell - September 18, 2023 Category: Molecular Biology Authors: Xiaoyan Zhi Shu Shi Yang Li Mingxia Ma Yaolin Long Chen Li Haihu Hao Huirong Liu Xiaohui Wang Li Wang Source Type: research
Piezo1 ：the potential new therapeutic target for fibrotic diseases
Prog Biophys Mol Biol. 2023 Sep 16:S0079-6107(23)00082-2. doi: 10.1016/j.pbiomolbio.2023.09.001. Online ahead of print.ABSTRACTFibrosis is a pathological process that occurs in various organs, characterized by excessive deposition of extracellular matrix (ECM), leading to structural damage and, in severe cases, organ failure. Within the fibrotic microenvironment, mechanical forces play a crucial role in shaping cell behavior and function, yet the precise molecular mechanisms underlying how cells sense and transmit these mechanical cues, as well as the physical aspects of fibrosis progression, remain less understood. Piezo1...
Source: Mol Biol Cell - September 18, 2023 Category: Molecular Biology Authors: Xin Liu Weipin Niu Shuqing Zhao Wenjuan Zhang Zhao Ying Jing Li Source Type: research
Monoamines' role in islet cell function and type 2 diabetes risk
Trends Mol Med. 2023 Sep 16:S1471-4914(23)00194-6. doi: 10.1016/j.molmed.2023.08.009. Online ahead of print.ABSTRACTThe two monoamines serotonin and melatonin have recently been highlighted as potent regulators of islet hormone secretion and overall glucose homeostasis in the body. In fact, dysregulated signaling of both amines are implicated in β-cell dysfunction and development of type 2 diabetes mellitus (T2DM). Serotonin is a key player in β-cell physiology and plays a role in expansion of β-cell mass. Melatonin regulates circadian rhythm and nutrient metabolism and reduces insulin release in human and rodent islets...
Source: Molecular Medicine - September 18, 2023 Category: Molecular Biology Authors: Fiona Louise Roberts Luis Rodrigo Cataldo Malin Fex Source Type: research
Interrelationship of hemoglobin A1c level lipid profile, uric acid, C-reactive protein levels and age in a large hospital database
CONCLUSION: At population level, HbA1c levels can be estimated almost exactly based on lipid profile, CRP and uric acid levels in female patients between 20 and 70 years.PMID:37722548 | DOI:10.1016/j.mcp.2023.101933
Source: Molecular Medicine - September 18, 2023 Category: Molecular Biology Authors: Dlovan Ali Jalal Barna V ásárhelyi B éla Blaha Zolt án Tóth Tam ás Géza Szabó B éla Gyarmati Source Type: research
A phase I/II study of the safety and efficacy of < sup > 177 < /sup > LuLu-satoreotide tetraxetan in advanced somatostatin receptor-positive neuroendocrine tumours
CONCLUSION: [177Lu]Lu-satoreotide tetraxetan, administered at a median cumulative activity of 13.0 GBq over three cycles, has an acceptable safety profile with a promising clinical response in patients with progressive, SSTR-positive NETs. A 5-year long-term follow-up study is ongoing.TRIAL REGISTRATION: ClinicalTrials.gov, NCT02592707. Registered October 30, 2015.PMID:37721581 | DOI:10.1007/s00259-023-06383-1
Source: Molecular Medicine - September 18, 2023 Category: Molecular Biology Authors: Damian Wild Henning Gr ønbæk Shaunak Navalkissoor Alexander Haug Guillaume P Nicolas Ben Pais Catherine Ansquer Jean-Mathieu Beauregard Alexander McEwan Michael Lassmann Daniele Pennestri Magali Volteau Nat P Lenzo Rodney J Hicks Source Type: research
Baseline < sup > 18 < /sup > FFDG PET features are associated with survival and toxicity in patients treated with CAR T cells for large B cell lymphoma
CONCLUSION: TMTV and sDmax had independent prognostic values, respectively, on PFS and OS. Regarding adverse events, the mean liver and spleen uptakes were associated with the occurrence of grade 2 to 4 CRS and ICANS, respectively. Integrating these biomarkers into the clinical workflow could be useful for early adaptation of patients management.PMID:37721580 | DOI:10.1007/s00259-023-06427-6
Source: Molecular Medicine - September 18, 2023 Category: Molecular Biology Authors: E Marchal X Palard-Novello F Lhomme M E Meyer G Manson A Devillers J P Marolleau R Houot A Girard Source Type: research
Improved diagnostic accuracy for coronary artery disease detection with quantitative 3D < sup > 82 < /sup > Rb PET myocardial perfusion imaging
CONCLUSIONS: Normal databases tailored to 3D PET images provide significantly improved diagnostic accuracy for PET MPI evaluation with automated quantitative TPD. Clinical application of these techniques should be considered to support accurate image interpretation.PMID:37721579 | DOI:10.1007/s00259-023-06414-x
Source: Molecular Medicine - September 18, 2023 Category: Molecular Biology Authors: Jennifer M Renaud Alexis Poitrasson-Rivi ère Jonathan B Moody Tomoe Hagio Edward P Ficaro Venkatesh L Murthy Source Type: research
Deep Learning-Based Feature Extraction from Whole-Body PET/CT Employing Maximum Intensity Projection Images: Preliminary Results of Lung Cancer Data
CONCLUSION: A 2-D image-based pre-trained model could extract image patterns of whole-body FDG PET volume by using anterior and lateral views of MIP images bypassing the direct use of 3-D PET volume that requires large datasets and resources. We suggest that this approach could be implemented as a backbone model for various applications for whole-body PET image analyses.PMID:37720886 | PMC:PMC10504178 | DOI:10.1007/s13139-023-00802-9
Source: Molecular Medicine - September 18, 2023 Category: Molecular Biology Authors: Joonhyung Gil Hongyoon Choi Jin Chul Paeng Gi Jeong Cheon Keon Wook Kang Source Type: research
Correction to: Sleep and Neuroimaging
Nucl Med Mol Imaging. 2023 Oct;57(5):256. doi: 10.1007/s13139-023-00807-4. Epub 2023 May 4.ABSTRACT[This corrects the article DOI: 10.1007/s13139-020-00636-9.].PMID:37720885 | PMC:PMC10504171 | DOI:10.1007/s13139-023-00807-4
Source: Molecular Medicine - September 18, 2023 Category: Molecular Biology Authors: Kyoungjune Pak Jiyoung Kim Keunyoung Kim Seong Jang Kim In Joo Kim Source Type: research
