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Breastfeeding and Childhood Leukemia Incidence: A Meta-analysis and Systematic Review.
Conclusions and Relevance: Breastfeeding is a highly accessible, low-cost public health measure. This meta-analysis that included studies not featured in previous meta-analyses on the subject indicates that promoting breastfeeding for 6 months or more may help lower childhood leukemia incidence, in addition to its other health benefits for children and mothers. PMID: 26030516 [PubMed - as supplied by publisher]
Source: Cancer Control - June 1, 2015 Category: Cancer & Oncology Authors: Amitay EL, Keinan-Boker L Tags: JAMA Pediatr Source Type: research

Breastfeeding and risk of childhood brain tumors: a report from the Childhood Cancer and Leukemia International Consortium
CONCLUSION: Our data suggest that breastfeeding does not protect against CBT.PMID:37421504 | DOI:10.1007/s10552-023-01746-3
Source: Cancer Control - July 8, 2023 Category: Cancer & Oncology Authors: Jeremy M Schraw Eleni Th Petridou Audrey Bonaventure John D Dockerty Maria Karalexi Evangelia Ntzani Claire Infante-Rivard Jacqueline Clavel Paige M Bracci Roberta McKean-Cowdin Eve Roman Eleanor Kane Friederike Erdmann Joachim Sch üz Beth A Mueller Mich Source Type: research

Preventing breastfeeding-associated hypernatraemia: an argument for supplemental feeding
The benefits of breastfeeding are unquestionable. Breast milk provides the ideal nourishment for infant growth and development. In addition, it has numerous health benefits for both infant and mother. Breastfeeding decreases the incidence of acute infections such as otitis media, respiratory tract infections and gastroenteritis; chronic diseases such as type 1 diabetes, asthma and inflammatory bowel disease, and childhood leukaemia and lymphoma; and sudden infant death syndrome. In addition, it improves neurodevelopmental outcomes for the infant. Breastfeeding benefits the mother by improving infant-maternal bonding, facil...
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - August 18, 2013 Category: Perinatology & Neonatology Authors: Moritz, M. L. Tags: Infection (gastroenterology), Oncology, Immunology (including allergy), Foodborne infections, Otitis, TB and other respiratory infections, Coma and raised intracranial pressure, Epilepsy and seizures, Childhood nutrition, Contraception, Family planning, R Source Type: research

Breastfeeding and Nutrition to 2 Years of Age and Risk of Childhood Acute Lymphoblastic Leukemia and Brain Tumors.
Abstract Acute lymphoblastic leukemia (ALL) and childhood brain tumors (CBT) are 2 of the most common forms of childhood cancer, but little is known of their etiology. In 2 nationwide case-control studies we investigated whether breastfeeding, age of food introduction, or early diet are associated with the risk of these cancers. Cases aged 0-14 years were identified from Australian pediatric oncology units between 2003 and 2007 (ALL) and 2005 and 2010 (CBT) and population-based controls through nationwide random-digit dialing. Mothers completed questionnaires giving details of infant feeding up to the age of 2 y...
Source: Nutrition and Cancer - February 3, 2015 Category: Cancer & Oncology Authors: Greenop KR, Bailey HD, Miller M, Scott RJ, Attia J, Ashton LJ, Downie P, Armstrong BK, Milne E Tags: Nutr Cancer Source Type: research

Protective effect of breastfeeding against childhood leukemia in Zhejiang Province, P. R. China: a retrospective case-control study.
CONCLUSIONS: This study indicates that promoting breastfeeding for 7-9 months may help lower the childhood leukemia incidence. Our study firstly demonstrates that breastfeeding has protective effects against childhood leukemia in the P. R. of China. ABBREVIATIONS: ALL: Acute lymphocytic leukemia; AML: Acute myeloid leukemia. PMID: 30138041 [PubMed - in process]
Source: Libyan Journal of Medicine - August 24, 2018 Category: General Medicine Tags: Libyan J Med Source Type: research

Association between maternal breastfeeding and risk of systemic neoplasms of offspring
ConclusionsThe evidences demonstrated that breastfeeding have a potential protective role in preventing selective childhood cancer growth, especially for ALL, AML, cancer of nervous and urinary systems. This study recommended that breastfeeding be extended for as long as possible or maintained for at least 6  months to prevent selective childhood cancer growth.
Source: Italian Journal of Pediatrics - June 16, 2022 Category: Pediatrics Source Type: research

Breastfeeding in patients with chronic myeloid leukaemia: case series with measurements of drug concentrations in maternal milk and review of literature
Breastfeeding in patients with chronic myeloid leukaemia (CML) who take tyrosine kinase inhibitors (TKIs) is not recommended but interruption of TKI treatment may cause the loss of remission. We observed the kinetics of the leukaemic clone in 3 women with CML in accordance with treatment interruptions for pregnancy and breastfeeding. The concentrations of nilotinib and imatinib in maternal milk were measured when the breastfeeding period was over. Nilotinib transfer into human breast milk was demonstrated for the first time and had a maximum concentration (Cmax) 129 ng/ml after 4 hours of the drug intake at a dose of 400 m...
Source: Mediterranean Journal of Hematology and Infectious Diseases - April 30, 2018 Category: Hematology Source Type: research

Every ounce counts: A call for comprehensive support for breastfeeding surgeons by the Association of Women Surgeons
Breastfeeding is a vital component of global health. Breastmilk is the optimal nutrition for infants, and breastfeeding confers unparalleled health benefits to women and children including decreased infant mortality and morbidity from infectious diseases, sudden infant death syndrome, necrotizing enterocolitis, leukemia, and chronic illnesses as well as lower rates of maternal breast and ovarian cancers and chronic diseases.1 Tragically, no country in the world meets minimum standards for breastfeeding established by the Global Breastfeeding Collective, led by the World Health Organization (WHO).
Source: American Journal of Surgery - January 4, 2022 Category: Surgery Authors: Helen M. Johnson, Madeline B. Torres, Leah C. Tatebe, Maria S. Altieri, from the Publications Committee of the Association of Women Surgeons Source Type: research

Breastfeeding and risk of childhood brain tumors: a report from the Childhood Cancer and Leukemia International Consortium
ConclusionOur data suggest that breastfeeding does not protect against CBT.
Source: Cancer Causes and Control - July 8, 2023 Category: Cancer & Oncology Source Type: research

Breastfeeding and Childhood Leukemia Incidence
To the Editor We read with interest the recent meta-analysis by Amitay and Keinan-Boker about breastfeeding and childhood leukemia incidence. The authors identified published case-control studies and reported an inverse association for breastfeeding for 6 months or more compared with breastfeeding for less than 6 months (summary odds ratio [OR] = 0.81; 95% CL: 0.73, 0.89). Nonetheless, we describe herein the effect of unmeasured confounding as an alternate explanation for the observed association.
Source: JAMA Pediatrics - November 1, 2015 Category: Pediatrics Source Type: research

Breast feeding could reduce the risk of childhood leukaemias
Commentary on: Amitay EL, Keinan-Boker L. Breastfeeding and childhood leukemia incidence: a meta-analysis and systematic review. JAMA Pediatr 2015;169:e151025. Implications for practice and research Breastfeeding reduces the risk of all childhood leukaemias; the effect is greater if feeding continued for more than 6 months. Collaborative networked care of children allows the collection of useful data that enable large cohort studies to be undertaken. Investigations of the effects of nutrition would be greatly improved by more detailed documentation of infants feeding in early life. Context Leukaemias are the most comm...
Source: Evidence-Based Nursing - June 20, 2016 Category: Nursing Authors: Michie, C. Tags: Child health, Immunology (including allergy), Drugs: CNS (not psychiatric), Childhood nutrition, Reproductive medicine, Paediatric oncology, Childhood nutrition (paediatrics), Child health, Infant health, Infant nutrition (including breastfeeding), Intern Source Type: research

Fostering a Positive Breastfeeding Environment for the Urologic Resident
As more female trainees enter the workforce,1 more urologic residents are likely to become breastfeeding mothers during their training. Breastfeeding has been shown to lower maternal incidence of hypertension, type 2 diabetes, and ovarian cancer.2 Additionally, children who are breastfed have lower incidences of several pediatric disorders including: sudden infant death syndrome (SIDS), childhood obesity, and childhood leukemia among others.2 The American Association of Pediatrics (AAP) recently released recommendations acknowledging the health advantages of continued breastfeeding beyond two years of age.
Source: Urology - June 19, 2023 Category: Urology & Nephrology Authors: Karis Buford, Mariela Martinez-Rivera, Arshia Sandozi, Katiana Vazquez-Rivera, Allison Polland Source Type: research

Milk supply related to childhood leukaemia treatment.
Abstract This literature review and case study answers the question: 'Do the late effects of childhood cranial radiation therapy include impacts on breastfeeding?' PubMed was searched for papers using the terms lactation and cranial radiotherapy or childhood cranial radiotherapy. The case study was written from one author's experience of helping a mother with a history of childhood cranial radiation therapy. The few available studies report a high rate of lactation failure in women who were treated with cranial radiation therapy for childhood cancer, but the exceptions indicate that lactation failure is not inevit...
Source: Breastfeeding Review - July 1, 2014 Category: Midwifery Authors: Hall G, McGuire E Tags: Breastfeed Rev Source Type: research