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Vaccination: Hepatitis Vaccine

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Total 90 results found since Jan 2013.

XXIV World Allergy Congress 2015
Table of Contents A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts Jae-Min Shin, Heung-Man Lee, Il-Ho Park A2 The efficacy of a 2-week course of oral steroid in the treatment of chronic spontaneous urticaria refractory to antihistamines Hyun-Sun Yoon, Gyeong Yul Park A3 The altered distribution of follicular t helper cells may predict a more pronounced clinical course of primary sjögren’s syndrome Margit Zeher A4 Betamethasone suppresses Th2 cell development induced by langerhans cell like dendr...
Source: World Allergy Organization Journal - April 18, 2016 Category: Allergy & Immunology Source Type: research

TH1 and TH2 Responses Are Influenced by HLA Antigens in Healthy Neonates Vaccinated with Recombinant Hepatitis B Vaccine.
Abstract The immune response to hepatitis B surface antigen (HBsAg) is influenced by several factors, of which HLA antigens and balanced secretion of Th1/Th2 cytokines play important roles. The aim of this study was to evaluate the influence of HLA antigens on cytokine secretion by HBsAg-stimulated peripheral blood mononuclear cells (PBMC) from healthy neonates vaccinated with recombinant HBsAg. PBMCs were isolated from 48 Iranian neonates vaccinated with a recombinant HBV vaccine. The cells were stimulated in vitro with rHBsAg and the concentration of IL-4, IL-10, IL-12 and IFN-γ were quantitated in culture supe...
Source: Iranian Journal of Allergy, Asthma and Immunology - December 1, 2012 Category: Allergy & Immunology Authors: Jafarzadeh A, Shokri F Tags: Iran J Allergy Asthma Immunol Source Type: research

Mutational Analysis of HBs Ag-Positive Mothers and Their Infected Children despite Immunoprophylaxis.
Abstract Hepatitis B vaccination is safe and effective, although breakthrough infection occasionally occurs in those who receive the vaccine and hepatitis B immunoglobulin (HBIg) prophylaxis. Sequence variation in their antigenic regions is one of the most powerful strategies that are used by viruses to escape recognition by B and T cell-mediated immune responses. The aim of this study was to explore the mutational profile of HBV in vertical transmission.Six HBsAg-positive mothers and their children who developed HBV infection despite immunoprophylaxis were enrolled. After extraction of HBV DNA from sera, the full...
Source: Iranian Journal of Allergy, Asthma and Immunology - September 4, 2013 Category: Allergy & Immunology Authors: Ghaziasadi A, Alavian SM, Norouzi M, Fazeli Z, Jazayeri SM Tags: Iran J Allergy Asthma Immunol Source Type: research

Human Leukocyte Antigens Influence the Antibody Response to Hepatitis B Vaccine.
Abstract Hepatitis B virus (HBV) infection and its sequelae such as cirrhosis and hepatocellular carcinoma has remained a serious public health problem throughout the world. The WHO strategy for effective control of HBV infection and its complications is mass vaccination of neonates and children within the framework of Expanded Programme on Immunization (EPI). Vaccination with hepatitis B surface antigen (HBsAg) induces protective antibody response (anti-HBs ≥ 10 IU/L) in 90-99% of vaccinees. The lack of response to HBsAg has been attributed to a variety of  immunological mechanisms, including defect in anti...
Source: Iranian Journal of Allergy, Asthma and Immunology - June 1, 2015 Category: Allergy & Immunology Authors: Jafarzadeh A, Bagheri-Jamebozorgi M, Nemati M, Golsaz-Shirazi F, Shokri F Tags: Iran J Allergy Asthma Immunol Source Type: research

Hepatitis C Virus Subtype 3a Envelope Protein 1 Binding with Human Leukocyte Antigen Class I Types of Pakistani Population: Candidate Epitopes for Synthetic Peptide Vaccine.
Abstract The object of this cross sectional study was to determine the HCV subtype 3a envelope protein binding affinity with Human Leukocyte Antigen. Envelope 1 (E1) protein is one of the structural proteins responsible for entering the cells through the receptors. The binding affinity of E1 protein epitopes to the selected Human Leukocyte Antigen (HLA) class I alleles was investigated using the computer-based tools. These prediction tools were also used to design the synthetic vaccine's candidate epitopes and to identify the individuals/populations who are likely to be responder to those vaccines.The mean frequen...
Source: Iranian Journal of Allergy, Asthma and Immunology - October 1, 2015 Category: Allergy & Immunology Authors: Nawaz-Tipu H Tags: Iran J Allergy Asthma Immunol Source Type: research

The Effect of Oral Levamisole Co-administration on the Level of Immune Response to Hepatitis B Vaccine in Healthy Individuals: A Randomized Clinical Trial.
Abstract Despite its proven efficacy, the hepatitis B vaccine requires improvements in immune enhancement and durability, especially in the elderly. Levamisole, an immune modulator, has been tested as an adjuvant to hepatitis B vaccine in several studies in immune-compromised populations. However, we aimed to evaluate the effect of levamisole on the immune response to hepatitis B vaccine in healthy subjects. In this randomized clinical trial, healthy family members of chronic hepatitis B patients were given twenty-microgram intramuscular injections of hepatitis B vaccine at 0, 1, and 6 months and 50 miligrams of o...
Source: Iranian Journal of Allergy, Asthma and Immunology - June 1, 2017 Category: Allergy & Immunology Authors: Hosseini M, Shalchiantabrizi P, Dadgarmoghaddam M, Ahmady-Simab S, Behjati A, Salari M Tags: Iran J Allergy Asthma Immunol Source Type: research

Higher Activities of Hepatic Versus Splenic CD8+ T Cells in Responses to Adoptive T Cell Therapy and Vaccination of B6 Mice with MHC Class-1 Binding Antigen.
Abstract The liver has unique microenvironment which is known to induce tolerance of cytolytic CD8+ T cells to hepatic and extra hepatic antigens, resulting in persistence of infection of the liver by the hepatitis B and C viruses. However, under some conditions, functional immune responses can be elicited in the liver in particular to show preferential retention of activated CD8+ T cells. It is not clear whether this retention depends on the type of the exogenous immunostimulatory or the endogenous innate immune cells. The T cell receptor (TCR) transgenic OT-1 (CD8+) mouse model was used in which OT-1 cells were ...
Source: Iranian Journal of Allergy, Asthma and Immunology - December 1, 2017 Category: Allergy & Immunology Authors: Salem ML, E El Naggar R, A El Naggar S, A Mobasher M, H Mahmoud M, Badr G Tags: Iran J Allergy Asthma Immunol Source Type: research

Hepatitis B vaccine non-responders: possible mechanisms and solutions.
CONCLUSION: This review will provide a background on the immunology of HBV infection, the possible immunologic mechanisms to explain HBV vaccine non-responsiveness, current research aimed at improving vaccine effectiveness, and possible future approaches for providing non-responders protection from HBV. PMID: 29567355 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - March 19, 2018 Category: Allergy & Immunology Authors: Saco TV, Strauss AT, Ledford DK Tags: Ann Allergy Asthma Immunol Source Type: research

Evidence Refuting the Existence of Autoimmune/Autoinflammatory Syndrome Induced  by Adjuvants (ASIA)
Publication date: Available online 6 September 2017 Source:The Journal of Allergy and Clinical Immunology: In Practice Author(s): Rohan Ameratunga, David Gillis, Michael Gold, Allan Linneberg, J. Mark Elwood Autoimmune/autoinflammatory syndrome induced by adjuvants (ASIA) was described in 2011. Over time the condition and its triggers have broadened to include several autoimmune disorders, the macrophagic myofasciitis syndrome, the Gulf war syndrome, the sick building syndrome, siliconosis, and the chronic fatigue syndrome. The aluminum-containing adjuvants in the hepatitis B vaccine and the human papillomavirus vaccine i...
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2017 Category: Allergy & Immunology Source Type: research

Safety and efficacy of immunotherapy with the recombinant B-cell epitope –based grass pollen vaccine BM32
BM32 is a grass pollen allergy vaccine based on recombinant fusion proteins consisting of nonallergenic peptides from the IgE-binding sites of the 4 major grass pollen allergens and the hepatitis B preS protein.
Source: Journal of Allergy and Clinical Immunology - January 17, 2018 Category: Allergy & Immunology Authors: Verena Niederberger, Angela Neubauer, Philippe Gevaert, Mihaela Zidarn, Margitta Worm, Werner Aberer, Hans J ørgen Malling, Oliver Pfaar, Ludger Klimek, Wolfgang Pfützner, Johannes Ring, Ulf Darsow, Natalija Novak, Roy Gerth van Wijk, Julia Eckl-Dorna, Source Type: research

Hepatitis B immunogenicity after a primary vaccination course associated with childhood asthma, allergic rhinitis, and allergen sensitization
Pediatric Allergy and Immunology,Volume 29, Issue 2, Page 221-224, March 2018.
Source: Pediatric Allergy and Immunology - December 21, 2017 Category: Allergy & Immunology Source Type: research

Safety and efficacy of immunotherapy with the recombinant B-cell epitope –based grass pollen vaccine BM32
BM32 is a grass pollen allergy vaccine based on recombinant fusion proteins consisting of nonallergenic peptides from the IgE-binding sites of the 4 major grass pollen allergens and the hepatitis B preS protein.
Source: Journal of Allergy and Clinical Immunology - January 17, 2018 Category: Allergy & Immunology Authors: Verena Niederberger, Angela Neubauer, Philippe Gevaert, Mihaela Zidarn, Margitta Worm, Werner Aberer, Hans J ørgen Malling, Oliver Pfaar, Ludger Klimek, Wolfgang Pfützner, Johannes Ring, Ulf Darsow, Natalija Novak, Roy Gerth van Wijk, Julia Eckl-Dorna, Source Type: research

True, true, and unrelated: Stop routine testing to vaccine excipients for suspected vaccine allergy
Vaccines for infectious diseases contain multiple minor ingredients called excipients, such as egg ovalbumin, polysorbate (PS), polyethylene glycol (PEG), neomycin, thimerosal, and other contaminants (eg, lactose, yeast, formaldehyde, gelatin, latex).1,2 Allergic reactions occurring to vaccines are rare, but focus on vaccine excipients as the provoking cause.3 Examples of this include egg ovalbumin in yellow fever (YF), gelatin in measles, mumps, and rubella (MMR) and several other vaccines, yeast in hepatitis B vaccines, and casein with diphtheria tetanus acellular pertussis (DTaP).
Source: Annals of Allergy, Asthma and Immunology - June 16, 2022 Category: Allergy & Immunology Authors: Matthew Greenhawt Tags: Perspective Source Type: research

Studies on HBcAg-rBlo t 5-21 Fusion Protein Vaccine That Alleviates < em > Blomia tropicalis < /em > Airway Inflammation
CONCLUSION: HBcAg-rBlo t 5-21, a protein vaccine containing both the hepatitis B core antigen and the Blomia tropicalis fusion allergen rBlo t 5-21, could be a suitable vaccination for preventing allergy disorders caused by Blomia tropicalis.PMID:36424919 | PMC:PMC9680538 | DOI:10.2147/JIR.S380526
Source: Cell Research - November 25, 2022 Category: Cytology Authors: Yechun Pei Zhengpan Xiao Shuangshuang Wei Meiqi Peng Chenghui Luo Dayong Wang Source Type: research

Humoral Immunity in Arsenic-Exposed Children in Rural Bangladesh: Total Immunoglobulins and Vaccine-Specific Antibodies
Conclusions: Arsenic exposure increased tIgG and tIgE in plasma, and tended to decrease mumps-specific IgG in children at 9 years of age. https://doi.org/10.1289/EHP318 Received: 09 April 2016 Revised: 09 October 2016 Accepted: 24 October 2016 Published: 14 June 2017 Address correspondence to R. Raqib, Immunobiology, Nutrition and Toxicology Laboratory, Infectious Diseases Division, icddr,b, 68 Shaheed Tajuddin Ahmed Sarani, Mohakhali, Dhaka-1212, Bangladesh. Telephone: 880-2-9827068. E-mail: rubhana@icddrb.org Supplemental Material is available online (https://doi.org/10.1289/EHP318). The authors declare they have n...
Source: EHP Research - June 15, 2017 Category: Environmental Health Authors: Karla Gonzalez Tags: Research Source Type: research