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Total 453 results found since Jan 2013.

Immunoglobulin E-binding Proteins of Cooked Walnuts in Korean Children.
CONCLUSIONS: The protein profile of boiled WNs is substantially different from that of raw WNs. However, 4 proteins including prolamins remained stable after dry-frying or boiling. Further studies are needed to evaluate the clinical relevance of these findings. PMID: 29949832 [PubMed]
Source: Allergy, Asthma and Immunology Research - June 28, 2018 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Monoclonal Antibodies to Recombinant Fag e 3 Buckwheat Allergen and Development of a Two-site ELISA for Its Quantification.
CONCLUSIONS: We have developed an ELISA system for the quantification of the group 3 buckwheat allergen, Fag e 3, specifically. This assay will be useful for standardization of buckwheat allergens and monitoring of buckwheat contamination in foods. PMID: 28677355 [PubMed]
Source: Allergy, Asthma and Immunology Research - July 6, 2017 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Effectiveness of intranasal sodium hyaluronate in mitigating adverse effects of nasal continuous positive airway pressure therapy.
CONCLUSION: Intranasal hyaluronate showed significant benefits in patients who received CPAP therapy, but future studies over a longer period of time after treatment should be performed to corroborate our findings. PMID: 28927491 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - September 19, 2017 Category: ENT & OMF Tags: Am J Rhinol Allergy Source Type: research

Alteration in Claudin-4 Contributes to Airway Inflammation and Responsiveness in Asthma.
CONCLUSIONS: These findings thus raise the possibility that regulation of lung epithelial barrier proteins may constitute a therapeutic approach for asthma. PMID: 29178675 [PubMed]
Source: Allergy, Asthma and Immunology Research - November 29, 2017 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

A randomized, double-blind, placebo-controlled study of the use of viscous oral cromolyn sodium for the treatment of eosinophilic esophagitis.
CONCLUSION: Cromolyn, when mixed into a viscous preparation, did not significantly reduce esophageal eosinophilia. It did however reduce symptom scores (although not significantly more than placebo) and led to complete resolution in one subject. PMID: 29544738 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - March 12, 2018 Category: Allergy & Immunology Authors: Lieberman JA, Zhang J, Whitworth J, Cavender C Tags: Ann Allergy Asthma Immunol Source Type: research

Production of Recombinant Protein of Salsola Kali (Sal k1) Pollen Allergen in Lactococcus Lactis.
This study demonstrated that L. lactis may be used as a promising live delivery system for recombinant Sal k1 protein without altering its immunoreactivity; however, its efficacy in the context of the immune system is suggested to be pursued in future studies. PMID: 29757586 [PubMed - in process]
Source: Iranian Journal of Allergy, Asthma and Immunology - April 1, 2018 Category: Allergy & Immunology Authors: Ghasemi Z, Varasteh AR, Moghadam M, Sedghi F, Jabbariazad F, Sankian M Tags: Iran J Allergy Asthma Immunol Source Type: research

Effect of Montelukast, a Cysteinyl Leukotriene Receptor-1 Antagonist, on a Rat Model of Acute Bacterial Sinonasal Inflammation.
CONCLUSION: This study histopathologically and molecularly showed that MONT significantly ameliorated the SA-associated sinonasal inflammatory reaction, both alone and in combination with CEFA. These results may suggest that MONT may block the inflammatory reaction underlying RS even more significantly by antioxidative or anti-inflammatory effects. This study suggests MONT as a future potential therapeutic agent for RS treatment. PMID: 31129976 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - May 26, 2019 Category: ENT & OMF Authors: Kaya Z, Yayla M, Cinar I, Celebi D, Toktay E, Bayraktutan Z, Bilici D Tags: Am J Rhinol Allergy Source Type: research

Suppression of aspirin-mediated eosinophil activation by prostaglandin E2: Relevance to aspirin/NSAID hypersensitivity.
CONCLUSION: Eosinophils can be directly activated by NSAIDs via cyclooxygenase independent pathways to produce CysLTs and LTB4. This effect can be inhibited by PGE2 acting through the EP2 receptor. The recognized loss of EP2 receptor expression combined with low PGE2 levels, explain in part the sensitivity to NSAIDs. PMID: 31513909 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - September 8, 2019 Category: Allergy & Immunology Authors: Pal K, Ramsden M, Shim YM, Borish L, Payne SC, Steinke JW Tags: Ann Allergy Asthma Immunol Source Type: research

Molecular Cloning, Expression and Purification of G-CSF Isoform D, an Alternative Splice Variant of Human G-CSF.
Abstract Granulocyte colony-stimulating factor (G-CSF) is the major regulator of hemopoiesis and granulopoiesis. However, overexpression of G-CSF has been implicated in several important processes in tumor biology such as tumor growth, angiogenesis, and metastasis. Four different mRNA isoforms resulting from alternative splicing have been reported for G-CSF (transcript variants 1, 2, 3 and 4). The mRNAs and protein products of splice variants 1 and 2 have been isolated for the first time, from tumor cell lines. In the present study for the first time we isolated the G-CSF transcript variant 4 encoding G-CSF isofor...
Source: Iranian Journal of Allergy, Asthma and Immunology - August 16, 2019 Category: Allergy & Immunology Authors: Toghraie FS, Yazdanpanah-Samani M, Mahmoudi Maymand E, Hosseini A, Asgari A, Ramezani A, Ghaderi A Tags: Iran J Allergy Asthma Immunol Source Type: research

High-level Expression and One-step Purification of Chimeric Antigen Containing HTLV-I-II Diagnostic Epitopes in Escherichia coli.
In this study, our aim was to design a chimeric protein for the simultaneous detection of HTLV-I and HTLV-II antibodies. Immunodominant B cell linear epitopes of envelope and capsid proteins of HTLV-I/-II were selected and linked together; using a suitable amino acid linker and a chimeric antigen (CA). The codon-optimized synthetic DNA encoding the CA was subcloned into the pGS21aexpression vector and CA expressed as His-GST fused protein in E. coli BL21 (DE3) cells. Then the recombinant CA was purified, using the Ni-NTA (Nickle Nitrilotriacetic acid) affinity chromatography under native conditions. The Sodium dodecyl su...
Source: Iranian Journal of Allergy, Asthma and Immunology - April 15, 2020 Category: Allergy & Immunology Authors: Bezhgi M, Fazilati M Tags: Iran J Allergy Asthma Immunol Source Type: research

In Vitro Effects of Sodium Benzoate on the Expression of T Cells-related Cytokines and Transcription Factors in Adjuvant-induced Arthritis Model.
In conclusion, NaB can potentially be considered as a useful therapeutic agent for the treatment of RA and other Th1 and Th17-mediated diseases. PMID: 32534510 [PubMed - as supplied by publisher]
Source: Iranian Journal of Allergy, Asthma and Immunology - May 16, 2020 Category: Allergy & Immunology Authors: Bemani P, Amirghofran Z, Kamali-Sarvestani E Tags: Iran J Allergy Asthma Immunol Source Type: research

Effect of an Antagonistic Peptide of CCR5 on the Expression of Autophagy-related Genes and β-Arrestin 2 in Lung Tissues of Asthmatic Mice.
CONCLUSIONS: HY peptide inhibits airway inflammation, autophagic dysfunction exists in asthmatic mice, and targeting HY peptide increases the expression of autophagy-related genes. Thus, β-arrestin 2 may participate in the mechanisms underlying these processes. PMID: 33191680 [PubMed]
Source: Allergy, Asthma and Immunology Research - November 18, 2020 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Severe asthmatic attack with cardiac arrest suspected to be induced by sulbactam sodium
We reported one case of severe asthmatic attack with cardiac arrest suspected to be induced by sulbactam sodium. A 74-year-old female received intravenous administration of mezlocillin sodium/sulbactam sodium for pulmonary infection complicated by bronchial asthma. After infusion of about 10 ml, the patient suddenly developed severe asthmatic attack and palpitations, then apnea and cardiac arrest. The patient was successfully rescued by glucocorticoids treatment and cardiopulmonary resuscitation. The above symptoms were considered to be caused by mezlocillin sodium/sulbactam sodium. Detailed investigation showed that the p...
Source: European Respiratory Journal - December 23, 2014 Category: Respiratory Medicine Authors: Zheng, W., Chen, Y., Zhao, L. Tags: 5.3 Allergy and Immunology Source Type: research

Sensitizing capacity and allergenicity of enzymatically cross-linked sodium caseinate in comparison to sodium caseinate in a mouse model for cow's milk allergy.
Abstract A transglutaminase cross-linked caseinate was designed for use in dairy products to increase the viscosity of food matrices. The difference in structure of cross-linked caseinate might have implications for the risk of developing cow's milk allergy. The sensitizing capacity and the allergenicity (the potency to induce an allergic effector response) of cross-linked sodium caseinate was investigated using a mouse model for cow's milk allergy. Mice were orally sensitized with cross-linked caseinate or caseinate using cholera toxin as adjuvant. Anaphylactic shock reactions, change in body temperature, acute a...
Source: Toxicology Letters - January 23, 2013 Category: Toxicology Authors: van Esch BC, Hest MG, Westerbeek H, Garssen J Tags: Toxicol Lett Source Type: research

An adult case of anaphylaxis caused by allergy to jellyfish.
AN ADULT CASE OF ANAPHYLAXIS CAUSED BY ALLERGY TO JELLYFISH. Arerugi. 2017;66(6):804-808 Authors: Suzuki S, Miyata Y, Jinno M, Kishino Y, Homma T, Ota S, Tanaka A, Yokoe T, Ohnishi T, Sagara H, Kurata N, Shimakura K, Kurose K Abstract A 35-year-old female, professional diver, reported nausea, vomiting, and systemic hives 20 to 30 minutes after ingestion of antipasto made with jellyfish. Patient reported prior episodes of swelling after stings from several different creatures, including jelly fish. She also developed a systemic allergic reaction after sting from an unknown creature while diving. On the...
Source: Arerugi - July 15, 2017 Category: Allergy & Immunology Authors: Suzuki S, Miyata Y, Jinno M, Kishino Y, Homma T, Ota S, Tanaka A, Yokoe T, Ohnishi T, Sagara H, Kurata N, Shimakura K, Kurose K Tags: Arerugi Source Type: research