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Infectious Disease: Aspergillosis

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Total 354 results found since Jan 2013.

XXIV World Allergy Congress 2015
Table of Contents A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts Jae-Min Shin, Heung-Man Lee, Il-Ho Park A2 The efficacy of a 2-week course of oral steroid in the treatment of chronic spontaneous urticaria refractory to antihistamines Hyun-Sun Yoon, Gyeong Yul Park A3 The altered distribution of follicular t helper cells may predict a more pronounced clinical course of primary sjögren’s syndrome Margit Zeher A4 Betamethasone suppresses Th2 cell development induced by langerhans cell like dendr...
Source: World Allergy Organization Journal - April 18, 2016 Category: Allergy & Immunology Source Type: research

Coexisting atopic conditions influence the likelihood of allergic bronchopulmonary aspergillosis in asthma.
CONCLUSION: The absence of atopic eczema and allergic rhinitis in these patients increases the likelihood of ABPA. Eliciting an accurate allergy history may be a useful bedside clinical tool when considering the diagnosis of ABPA. PMID: 27234940 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - May 23, 2016 Category: Allergy & Immunology Authors: Tay TR, Bosco J, Gillman A, Aumann H, Stirling R, O'Hehir R, Hew M Tags: Ann Allergy Asthma Immunol Source Type: research

Can Controlling Endoplasmic Reticulum Dysfunction Treat Allergic Inflammation in Severe Asthma With Fungal Sensitization?
Authors: Jeong JS, Kim SR, Lee YC Abstract Severe asthma is a heterogeneous disease entity to which diverse cellular components and pathogenetic mechanisms contribute. Current asthma therapies, including new biologic agents, are mainly targeting T helper type 2 cell-dominant inflammation, so that they are often unsatisfactory in the treatment of severe asthma. Respiratory fungal exposure has long been regarded as a precipitating factor for severe asthma phenotype. Moreover, as seen in clinical definitions of allergic bronchopulmonary aspergillosis (ABPA) and severe asthma with fungal sensitization (SAFS), fungal al...
Source: Allergy, Asthma and Immunology Research - February 8, 2018 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

When to suspect and work up allergic bronchopulmonary aspergillosis.
PMID: 23806451 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - June 30, 2013 Category: Allergy & Immunology Authors: Greenberger PA Tags: Ann Allergy Asthma Immunol Source Type: research

Dissociation between sensitizing and colonizing fungi in patients with allergic bronchopulmonary aspergillosis.
CONCLUSION: Multiple fungal species can colonize the airway, and dissociation between colonizing and sensitizing species frequently occurs in definitive ABPA. Considering the increased prevalence of azole-resistant Aspergillus spp., administering antifungal drugs that target A. fumigatus without identifying which fungal species colonize the airway might be problematic. PMID: 23987194 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - September 1, 2013 Category: Allergy & Immunology Authors: Matsuse H, Tsuchida T, Fukahori S, Kawano T, Nishino T, Fukushima C, Kohno S Tags: Ann Allergy Asthma Immunol Source Type: research

Disseminated aspergillosis as the herald manifestation of chronic granulomatous disease in an adult patient.
We report a disseminated aspergillosis as the representative of adult onset chronic granulomatous disease without previous infection, with dramatic response to combination of antifungal and interferon therapy.  PMID: 24338231 [PubMed - in process]
Source: Iranian Journal of Allergy, Asthma and Immunology - December 19, 2013 Category: Allergy & Immunology Authors: Alavi Darazam I, Akhavan Zanjani H, Sanaee D, Tabarsi P, Alavi Moghaddam M, Mansouri D Tags: Iran J Allergy Asthma Immunol Source Type: research

Advances in environmental and occupational disorders in 2013
In this review of articles published in the Journal in 2013, we report on the significant advances in environmental and occupational disorders. Research advances have led to the identification and defined the structure and function of several major allergens. A meta-analysis confirmed the importance of mold exposure in patients with allergic rhinitis, and a new immunologic classification of aspergillosis emerged. Insights into the role of diesel exhaust particles in patients with severe asthma were clarified. Improvements in stinging insect allergy diagnostics were reported. Genetic, immunologic, and biomarker studies adv...
Source: Journal of Allergy and Clinical Immunology - April 28, 2014 Category: Allergy & Immunology Authors: David B. Peden, Robert K. Bush Tags: Advances in allergy, asthma, and immunology series 2014 Source Type: research

Potential benefit of omalizumab in respiratory diseases.
CONCLUSION: Recent insight into the immunopathology of respiratory diseases should be used to identify patient populations likely to respond to anti-IgE therapy. Controlled clinical trials are needed to confirm efficacy and determine the clinical significance of the effects of omalizumab in these populations. PMID: 25442695 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - November 1, 2014 Category: Allergy & Immunology Authors: Bonini M, Di Maria G, Paggiaro P, Rossi A, Senna G, Triggiani M, Canonica GW Tags: Ann Allergy Asthma Immunol Source Type: research

Molecular‐based allergy diagnosis of allergic bronchopulmonary aspergillosis in Aspergillus fumigatus‐sensitized Japanese patients
Conclusions & Clinical RelevanceThe levels of IgE to Asp f 1 and/or Asp f 2 can effectively differentiate ABPA from Af‐sensitized asthma, suggesting that the amounts of IgE specific for these molecules are markers for genuine Af‐sensitization in ABPA. However, comorbid AD must be taken into consideration in the interpretation of high IgE to Asp f 6. Establishing of IgE‐sensitization profiles using panel of Af‐allergen components provides valuable information for distinguishing genuine versus cross‐reactive sensitization in Af‐sensitized patients.This article is protected by copyright. All rights reserved.
Source: Clinical and Experimental Allergy - June 28, 2015 Category: Allergy & Immunology Authors: Hidenori Tanimoto, Yuma Fukutomi, Hiroshi Yasueda, Yasuo Takeuchi, Akemi Saito, Kentaro Watai, Kiyoshi Sekiya, Takahiro Tsuburai, Koichiro Asano, Masami Taniguchi, Kazuo Akiyama Tags: Original Article‐Allergens Source Type: research

Omalizumab, an additional therapy for allergic bronchopulmonary aspergillosis.
PMID: 26162570 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - July 7, 2015 Category: Allergy & Immunology Authors: Evans MO, Morris MJ, Coop CA, Evans SE Tags: Ann Allergy Asthma Immunol Source Type: research

Efficacy of preoperative itraconazole in allergic fungal rhinosinusitis.
CONCLUSION: We found improvements in clinical, radiologic, and endoscopic parameters in AFS after preoperative itraconazole administration, which decreased the disease load significantly and also reduced the extent of surgery in the short-term follow-up. It may prove to be a good preoperative adjunct that needs further research. PMID: 26163250 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - July 1, 2015 Category: ENT & OMF Authors: Patro SK, Verma RK, Panda NK, Chakrabarti A, Singh P Tags: Am J Rhinol Allergy Source Type: research

Eosinophilic Granulomatosis with Polyangiitis preceding allergic bronchopulmonary aspergillosis.
Authors: Lee W, Teo FS, Santosa A, Teng GG Abstract A 61-year-old Chinese man with long-standing, stable Eosinophilic Granulomatosis with Polyangiitis (EGPA) and asthma, presented with acute hypoxemia and declining obstructive pulmonary function. Elevated serum IgE levels, positive Aspergillus fumigatus specific IgE and CT findings of central bronchiectasis with small airway mucoid impaction confirmed new development of Allergic Bronchopulmonary Aspergillosis (ABPA). The maintenance therapy for EGPA, azathioprine, was discontinued. Prednisolone 0.5mg/kg/day and Itraconazole improved his symptoms and IgE levels. To ...
Source: European Annals of Allergy and Clinical Immunology - November 11, 2015 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Acute invasive fungal rhinosinusitis: Survival analysis and the prognostic indicators.
CONCLUSIONS: Palatal involvement was associated with a higher mortality in our study. Also, leukocyte counts, neutrophile counts, and CRP values had a significant impact on survival function. The reversal of the underlying disease and immunosuppression is as important as the medical and surgical treatment. PMID: 26637563 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - November 1, 2015 Category: ENT & OMF Authors: Gode S, Turhal G, Ozturk K, Aysel A, Midilli R, Karci B Tags: Am J Rhinol Allergy Source Type: research

Allergic Bronchopulmonary Aspergillosis: A Perplexing Clinical Entity.
Authors: Shah A, Panjabi C Abstract In susceptible individuals, inhalation of Aspergillus spores can affect the respiratory tract in many ways. These spores get trapped in the viscid sputum of asthmatic subjects which triggers a cascade of inflammatory reactions that can result in Aspergillus-induced asthma, allergic bronchopulmonary aspergillosis (ABPA), and allergic Aspergillus sinusitis (AAS). An immunologically mediated disease, ABPA, occurs predominantly in patients with asthma and cystic fibrosis (CF). A set of criteria, which is still evolving, is required for diagnosis. Imaging plays a compelling role in th...
Source: Allergy, Asthma and Immunology Research - April 30, 2016 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Allergic bronchopulmonary aspergillosis complicating Swyer-James-Macleod's syndrome: case report and review of literature.
Authors: Sehgal IS, Dhooria S, Behera D, Agarwal R Abstract Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disorder that results from immune responses mounted against antigens of Aspergillus fumigatus, resulting in non-specific respiratory symptoms and structural lung damage. Classically defined in individuals suffering from bronchial asthma and cystic fibrosis, ABPA has recently been described in other lung diseases including COPD, pulmonary tuberculosis, idiopathic bronchiectasis and others. Herein, we report the first case of ABPA complicating Swyer-James-Macleod's syndrome that was successfully t...
Source: European Annals of Allergy and Clinical Immunology - May 8, 2016 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research