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Total 211 results found since Jan 2013.

Choosing wisely in the era of biologics for asthma
In the era of biologics for asthma, clinicians, researchers, and guideline developers face an increasingly important challenge. In addition to critically appraising the evidence for efficacy of novel therapies for specific asthma phenotypes, we must consider the real-life cost and effectiveness of increasingly personalized medicine. Put simply, we must consider health economics and prescribe wisely.
Source: Annals of Allergy, Asthma and Immunology - April 1, 2018 Category: Allergy & Immunology Authors: M. Diane Lougheed Tags: Guest Editorial Source Type: research

Impact of increasing treatment rates on cost-effectiveness of subcutaneous immunotherapy (SCIT) in respiratory allergy: a decision analytic modelling approach
ConclusionsMeasures to increase SCIT initiation rates should be implemented and also address improving adherence.
Source: The European Journal of Health Economics - March 24, 2018 Category: Health Management Source Type: research

The economic advantage of allergen immunotherapy over drug treatment in respiratory allergy.
Authors: Incorvaia C, Gritti BL, Ridolo E PMID: 29295630 [PubMed - as supplied by publisher]
Source: Journal of Medical Economics - January 5, 2018 Category: Health Management Tags: J Med Econ Source Type: research

Are multiple sinus cultures necessary during sinus surgery for chronic rhinosinusitis?
ConclusionIn this retrospective review we showed that, for the practitioner who obtains sinus cultures intraoperatively, limiting this practice to a single culture rather than multiple is cost‐effective and sufficient for identifying the pathogen to be treated. This study, and the resultant change in practice, has the potential to reduce healthcare costs associated with the surgical care of the patient with CRS.
Source: International Forum of Allergy and Rhinology - January 5, 2018 Category: Allergy & Immunology Authors: Craig Miller, Greg E. Davis Tags: ORIGINAL ARTICLE Source Type: research

Cost-effectiveness of grass pollen subcutaneous immunotherapy (SCIT) compared to sublingual immunotherapy (SLIT) and symptomatic treatment in Austria, Spain and Switzerland.
CONCLUSION: In patients with allergic rhinitis, SIT offers cost-effective treatment options compared to symptomatic treatment. When comparing SCIT (Allergovit) and SLIT (Oralair), SCIT was dominant in terms of QALYs as well as costs, in particular due to a slightly higher patient compliance and lower drug costs. PMID: 29271271 [PubMed - as supplied by publisher]
Source: Journal of Medical Economics - December 23, 2017 Category: Health Management Tags: J Med Econ Source Type: research

Decomposition Analysis of Black –White Disparities in Birth Outcomes: The Relative Contribution of Air Pollution and Social Factors in California
Conclusions: Our results suggest that, although the role of individual and neighborhood factors remains prevailing in explaining black–white differences in birth outcomes, the individual contribution of PM2.5 is comparable in magnitude to any single individual- or neighborhood-level factor. https://doi.org/10.1289/EHP490 Received: 10 May 2016 Revised: 16 December 2016 Accepted: 03 January 2017 Published: 04 October 2017 Address correspondence to T. Benmarhnia, Department of Family Medicine and Public Health, and Scripps Institution of Oceanography, University of California, San Diego, 9500 Gilman Drive, La Jolla, C...
Source: EHP Research - October 4, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Asthma Cost-Effectiveness Analyses: Are We Using the Recommended Outcomes in Estimating Value?
Conclusions Although the use of NIH-recommended asthma core outcomes has improved, there is still room for improvement in using supplemental and emerging outcomes. To allow robust cross-study comparisons, future work should focus on further standardizing of data sources and methods.
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 28, 2017 Category: Allergy & Immunology Source Type: research

Fatal anaphylaxis: mortality rate and risk factors - Turner PJ, Jerschow E, Umasunthar T, Lin R, Campbell DE, Boyle RJ.
Up to 5% of the US population has suffered anaphylaxis. Fatal outcome is rare, such that even for people with known venom or food allergy, fatal anaphylaxis constitutes less than 1% of total mortality risk. The incidence of fatal anaphylaxis has not increa...
Source: SafetyLit - September 13, 2017 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Associations between Greenness, Impervious Surface Area, and Nighttime Lights on Biomarkers of Vascular Aging in Chennai, India
Conclusion: Greenness, ISA, and NTL were associated with increased SBP, DBP, and cPP, and with reduced FMD, suggesting a possible additional EVA pathway for the relationship between urbanization and increased CVD prevalence in urban India. https://doi.org/10.1289/EHP541 Received: 20 May 2016 Revised: 03 January 2017 Accepted: 23 January 2017 Published: 02 August 2017 Address correspondence to K.J. Lane, Yale School of Forestry and Environmental Studies, 195 Prospect Street, New Haven, CT 06511 USA. Telephone: (781) 696-4537; Email: kevin.lane@yale.edu Supplemental Material is available online (https://doi.org/10.1289...
Source: EHP Research - August 2, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Expert panel on practice patterns in the management of cow's milk protein allergy and associated economic burden of disease on health service in Turkey.
CONCLUSIONS: In conclusion, in providing the first health economic data on CMPA in Turkey, our findings revealed that CMPA imposes a substantial burden on the Turkish healthcare system from both payer perspective and societal perspective and indicated clinical nutrition as a primary cost driver. Management of infants presented with eczema, exclusively formula-fed infants, and first line use of AAF were associated with higher estimates for 2-year direct medical costs. PMID: 28602101 [PubMed - as supplied by publisher]
Source: Journal of Medical Economics - June 14, 2017 Category: Health Management Tags: J Med Econ Source Type: research

Economics of Chronic Rhinosinusitis
The objective of this article is to provide an updated review of the economic burden of chronic rhinosinusitis (CRS) and discuss how both medical and surgical interventions impact direct and indirect costs related to CRS. By understanding the economics of CRS, clinicians may improve the patient-centeredness of their care and help distinguish between low and high value interventions.Recent FindingsDirect costs related to CRS are primarily driven by outpatient physician visits, prescription medical therapy, and endoscopic sinus surgery (ESS). CRS produces large indirect costs and these costs often vary based on the severity ...
Source: Current Allergy and Asthma Reports - March 23, 2017 Category: Allergy & Immunology Source Type: research

Multiple Threats to Child Health from Fossil Fuel Combustion: Impacts of Air Pollution and Climate Change
Conclusion: Going beyond the powerful scientific and economic arguments for urgent action to reduce the burning of fossil fuels is the strong moral imperative to protect our most vulnerable populations. Citation: Perera FP. 2017. Multiple threats to child health from fossil fuel combustion: impacts of air pollution and climate change. Environ Health Perspect 125:141–148; http://dx.doi.org/10.1289/EHP299 Address correspondence to F.P. Perera, Department of Environmental Health Sciences, Columbia Center for Children’s Environmental Health, Columbia University Mailman School of Public Health, 722 West 168th St. 12th flo...
Source: EHP Research - February 1, 2017 Category: Environmental Health Authors: Web Admin Tags: Commentaries Children's Health February 2017 Source Type: research

Protease inhibitor monotherapy was non-inferior and cost-effective as maintenance therapy compared to triple therapy in viral load suppressed patients with HIV-1 infection
Commentary on: Paton NI, Stöhr W, Oddershede L, et al.. The Protease Inhibitor Monotherapy Versus Ongoing Triple Therapy (PIVOT) trial: a randomised controlled trial of a protease inhibitor monotherapy strategy for long-term management of human immunodeficiency virus infection. Health Technol Assess 2016;20:1–158 . Context Over the last 20 years, little has changed in terms of HIV treatment paradigm, being a three-drug regimen the standard of care for initial therapy. However, for reasons of virological plausibility, toxicity and costs, clinical researchers have explored the alternatives of switching vir...
Source: Evidence-Based Medicine - September 22, 2016 Category: Internal Medicine Authors: Ripamonti, D. Tags: Sexual transmitted infections (viral), Health policy, Clinical trials (epidemiology), Immunology (including allergy), HIV/AIDS, Health economics, Health service research Therapeutics/prevention Source Type: research

Enhancing Respiratory Medication Adherence: The Role of Health Care Professionals and Cost-Effectiveness Considerations
Publication date: September–October 2016 Source:The Journal of Allergy and Clinical Immunology: In Practice, Volume 4, Issue 5 Author(s): Job F.M. van Boven, Dermot Ryan, Michelle N. Eakin, Giorgio W. Canonica, Aji Barot, Juliet M. Foster Adherence to medication comprises a multiphased temporal process involving (1) initiation of prescribed therapy, (2) implementation as prescribed, and (3) subsequent persistence. Medication adherence remains suboptimal in most patients with long-term respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). Interventions have been shown to effectively impr...
Source: The Journal of Allergy and Clinical Immunology: In Practice - August 30, 2016 Category: Allergy & Immunology Source Type: research