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Neuroimmune Pathways and Allergic Disease: An Overview
There is increasing evidence that the nervous system and immune system are closely interlinked and that their interactions can influence the development of allergic diseases. Immune cells, such as mast cells, dendritic cells (DCs), macrophages, and innate lymphoid cells (ILCs), demonstrate bidirectional communication with neurons through cytokines, inflammatory mediators, neuropeptides, and neurotransmitters1, linking immune dysregulation with subsequent allergic symptoms such as gastrointestinal (GI) pain, cough, wheezing, and pruritus (Figure 1).
Source: Annals of Allergy, Asthma and Immunology - July 28, 2023 Category: Allergy & Immunology Authors: Andrew Long, Jenika Josephine Ferretti-Gallon, Andrew Ryan Chin, R. Sharon Chinthrajah, Sayantani Bhattacharya Sindher Tags: Perspective Source Type: research
Neuroimmune pathways and allergic disease
There is increasing evidence that the nervous system and immune system are closely interlinked and that their interactions can influence the development of allergic diseases. Immune cells, such as mast cells, dendritic cells (DCs), macrophages, and innate lymphoid cells (ILCs), exhibit bidirectional communication with neurons through cytokines, inflammatory mediators, neuropeptides, and neurotransmitters,1 linking immune dysregulation with subsequent allergic symptoms such as gastrointestinal (GI) pain, cough, wheezing, and pruritus (Fig 1).
Source: Annals of Allergy, Asthma and Immunology - July 28, 2023 Category: Allergy & Immunology Authors: Andrew Long, Jenika Josephine Ferretti-Gallon, Andrew Ryan Chin, R. Sharon Chinthrajah, Sayantani Bhattacharya Sindher Tags: Perspective Source Type: research
Therapy resistant urticaria as a long-term symptom of an incomplete Schnitzler syndrome
Recurring therapy resistant hives, accompanied by IgM-gammopathy, fever and joint pain can indicate Schnitzler syndrome, a rare autoimmune disorder. There is currently no approved treatment, but complete remis...
Source: Allergy, Asthma and Clinical Immunology - July 26, 2023 Category: Allergy & Immunology Authors: Viktoria Puxkandl, Antonia Currie, Wolfram Hoetzenecker and Sabine Altrichter Tags: Case report Source Type: research
Prospective study of an amino acid-based elemental diet in an eosinophilic gastritis and gastroenteritis nutrition trial
CONCLUSION: An amino acid-based elemental diet improves histologic, endoscopic, symptomatic, quality-of-life, and molecular parameters of EoG/EoGE; these findings and disease recurrence with food trigger reintroduction support a dominant role for food allergens in disease pathogenesis.CLINICALTRIALS: gov Identifier: NCT03320369.PMID:37462600 | DOI:10.1016/j.jaci.2023.05.024
Source: Pain Physician - July 18, 2023 Category: Anesthesiology Authors: Nirmala Gonsalves Bethany Doerfler Angelika Zalewski Guang-Yu Yang Lisa J Martin Xue Zhang Tetsuo Shoda Michael Brusilovsky Seema Aceves Kathy Thompson Amanda K Rudman Spergel Glenn Furuta Marc E Rothenberg Ikuo Hirano Source Type: research
Early intervention improves clinical responses to seasonal allergic rhinitis by stimulation in sphenopalatine ganglion (Xinwu acupoint)
CONCLUSIONS: The results of this study confirmed that early intervention by sphenopalatine ganglion (Xinwu acupoint) stimulation can effectively improve the symptoms and the quality of SAR patients' daily lives.PMID:37454264 | PMC:PMC10320438 | DOI:10.19852/j.cnki.jtcm.20230524.001
Source: Journal of Traditional Chinese Medicine - July 16, 2023 Category: Complementary Medicine Authors: Guo Yuhao Huang Liangran Zhang Lei Yang Wei Huang Lixia Liu Wei Fan Yuyan Source Type: research
