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Condition: Arthritis
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Total 2071 results found since Jan 2013.
Surgical technique and preliminary results of a moulded, mobile spacer for the treatment of periprosthetic joint infection of the knee
Oper Orthop Traumatol. 2023 Apr 3. doi: 10.1007/s00064-023-00803-z. Online ahead of print.ABSTRACTOBJECTIVE: Mobile knee spacers can be utilized in the first stage of a two-stage exchange in periprosthetic joint infection or septic arthritis of the knee to prevent soft tissue contraction, enable local antibiotic elution, and improve patient mobility. Commercially made moulds enable the surgeon to prepare a reproducible spacer design and match the preparation of the arthroplasty, which will be carried out in a second step.INDICATIONS: Periprosthetic joint infection of the knee and severe cases of septic arthritis of the kne...
Source: Operative Orthopadie und Traumatologie - April 3, 2023 Category: Orthopaedics Authors: Max Jaenisch Mari Babasiz Soufian Ben Amar Eva L ück Martin Gathen Dieter Christian Wirtz Thomas Martin Randau Source Type: research
New STELARA ® (ustekinumab) Long-Term Data Support its Established Safety Profile in Inflammatory Bowel Disease and Durable Efficacy in Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, March 4, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced final pooled long-term safety results for STELARA® (ustekinumab) through five years in adults with moderately to severely active Crohn’s disease (CD) and four years in adults with moderately to severely active ulcerative colitis (UC), as well as final four-year clinical and endoscopic outcomes from the UNIFI long-term extension (LTE) study evaluating the efficacy of STELARA for the treatment of adults with moderately to severely active UC.1,2 These data are a part of Janssen’s 22 oral and poster ...
Source: Johnson and Johnson - March 4, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news
Differences in IgG autoantibody Fab glycosylation across autoimmune diseases
CONCLUSION: Our data indicate that in chronic but not acute B cell-mediated autoimmune diseases disease-specific autoantibodies are enriched for Fab glycans.PMID:36716825 | DOI:10.1016/j.jaci.2022.10.035
Source: Herpes - January 30, 2023 Category: Infectious Diseases Authors: Jana Koers Rocco Sciarrillo Ninotska I L Derksen Esther M Vletter Yvonne E Filli é-Grijpma Elisabeth Raveling-Eelsing Nuno A G Gra ça Thiemo Leijser Hendri H Pas L Laura van Nijen-Vos Maaike V J Braham Anne-Marie Buisman Jan de Jong Angela I Schriek Ann Source Type: research
Is your kid actin out? A series of six patients with inherited ARPC1B deficiency and review of the literature
CONCLUSION: ARPC1B deficiency has a variable and heterogeneous clinical spectrum, expanded by these cases to include keloid scars and Epstein-Barr virus chronic hepatitis. A novel deletion in exon 8 is shared by three unrelated families and might be the result of a founder effect.PMID:36708766 | DOI:10.1016/j.jaip.2022.12.045
Source: Clinical Lung Cancer - January 28, 2023 Category: Cancer & Oncology Authors: Estefan ía Vásquez-Echeverri Marco Antonio Yamazaki-Nakashimada Edna Venegas Montoya Selma Cecilia Scheffler Mendoza Lina Maria Castano-Jaramillo Edgar Alejandro Medina-Torres Maria Edith Gonz ález-Serrano Melissa Espinosa-Navarro Juan Carlos Bustamant Source Type: research
Identification of New Potential Allergens from Green-lipped Mussel (Perna Canaliculus)
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):711-715. doi: 10.18502/ijaai.v21i6.11532.ABSTRACTThe green-lipped mussel (Perna canaliculus) originates from New Zealand. To preserve the health benefits of green-lipped mussel meat, it is freeze-dried to make a long-lasting powder. The powder is used to treat arthritis because of its potential anti-inflammatory properties. The report describes a 54-year-old woman who developed immediate rhinoconjunctival and respiratory symptoms after inhaling green-lipped mussel powder she gave to her dog for arthritis. A skin prick test with green-lipped mussel powder was performed. Prote...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Paula Kage Kristin Schubert Regina Treudler Jan-Christoph Simon Martin Von Bergen Janina Tomm Source Type: research
MicroRNAs Targeting Programmed Cell Death Protein 1 (PD-1) Promote Natural Killer Cell Exhaustion in Rheumatoid Arthritis
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):646-656. doi: 10.18502/ijaai.v21i6.11524.ABSTRACT Natural killer (NK) cells play a role in the pathogenesis of rheumatoid arthritis (RA). Upregulated levels of programmed cell death protein 1 (PD-1) is a sign of exhausted NK cells that could be regulated by microRNAs (miRNAs). In this investigation, we determined PD‑1 expression on NK cells (as a representation of NK cell exhaustion) in RA patients and evaluated if miRNAs are involved in the modulation of PD-1 expression in NK cells. Peripheral blood specimens were obtained from 40 RA patients and 20 healthy subjects. NK c...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Maryam Hemmatzadeh Elham Ahangar Parvin Alireza Ghanavatinejad Narges Rostami Mehrzad Hajaliloo Navid Shomali Hamed Mohammadi Farhad Jadidi-Niaragh Source Type: research
Importance of STAT3 Polymorphisms on the Risk and Clinical Characteristics of Rheumatoid Arthritis
In this study, we intended to evaluate the association of two miRSNPs with the risk of RA development and its clinical features. We studied 120 Iranian patients with RA and 125 non-RA subjects as controls. The genotypes and alleles of rs1053005 and rs1053023 in each individual were assessed by the high-resolution melting method. The distribution of STAT3 variants did not differ markedly in RA patients compared to healthy controls. Stratification analysis revealed that rs1053005 was linked with a higher concentration of C-reactive protein and an increased erythrocyte sedimentation rate, two indicators of inflammation and di...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Amirhossein Salehi Ebrahim Hazrati Hamta Ranjbar Javad Behroozi Bahram Pakzad Maryam Mousavi Mojtaba Mousavi Marzieh Hossein Balam Mansour Salesi Source Type: research
Identification of New Potential Allergens from Green-lipped Mussel (Perna Canaliculus)
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):711-715. doi: 10.18502/ijaai.v21i6.11532.ABSTRACTThe green-lipped mussel (Perna canaliculus) originates from New Zealand. To preserve the health benefits of green-lipped mussel meat, it is freeze-dried to make a long-lasting powder. The powder is used to treat arthritis because of its potential anti-inflammatory properties. The report describes a 54-year-old woman who developed immediate rhinoconjunctival and respiratory symptoms after inhaling green-lipped mussel powder she gave to her dog for arthritis. A skin prick test with green-lipped mussel powder was performed. Prote...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Paula Kage Kristin Schubert Regina Treudler Jan-Christoph Simon Martin Von Bergen Janina Tomm Source Type: research
MicroRNAs Targeting Programmed Cell Death Protein 1 (PD-1) Promote Natural Killer Cell Exhaustion in Rheumatoid Arthritis
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):646-656. doi: 10.18502/ijaai.v21i6.11524.ABSTRACT Natural killer (NK) cells play a role in the pathogenesis of rheumatoid arthritis (RA). Upregulated levels of programmed cell death protein 1 (PD-1) is a sign of exhausted NK cells that could be regulated by microRNAs (miRNAs). In this investigation, we determined PD‑1 expression on NK cells (as a representation of NK cell exhaustion) in RA patients and evaluated if miRNAs are involved in the modulation of PD-1 expression in NK cells. Peripheral blood specimens were obtained from 40 RA patients and 20 healthy subjects. NK c...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Maryam Hemmatzadeh Elham Ahangar Parvin Alireza Ghanavatinejad Narges Rostami Mehrzad Hajaliloo Navid Shomali Hamed Mohammadi Farhad Jadidi-Niaragh Source Type: research
Importance of STAT3 Polymorphisms on the Risk and Clinical Characteristics of Rheumatoid Arthritis
In this study, we intended to evaluate the association of two miRSNPs with the risk of RA development and its clinical features. We studied 120 Iranian patients with RA and 125 non-RA subjects as controls. The genotypes and alleles of rs1053005 and rs1053023 in each individual were assessed by the high-resolution melting method. The distribution of STAT3 variants did not differ markedly in RA patients compared to healthy controls. Stratification analysis revealed that rs1053005 was linked with a higher concentration of C-reactive protein and an increased erythrocyte sedimentation rate, two indicators of inflammation and di...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Amirhossein Salehi Ebrahim Hazrati Hamta Ranjbar Javad Behroozi Bahram Pakzad Maryam Mousavi Mojtaba Mousavi Marzieh Hossein Balam Mansour Salesi Source Type: research
MicroRNAs Targeting Programmed Cell Death Protein 1 (PD-1) Promote Natural Killer Cell Exhaustion in Rheumatoid Arthritis
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):646-656. doi: 10.18502/ijaai.v21i6.11524.ABSTRACT Natural killer (NK) cells play a role in the pathogenesis of rheumatoid arthritis (RA). Upregulated levels of programmed cell death protein 1 (PD-1) is a sign of exhausted NK cells that could be regulated by microRNAs (miRNAs). In this investigation, we determined PD‑1 expression on NK cells (as a representation of NK cell exhaustion) in RA patients and evaluated if miRNAs are involved in the modulation of PD-1 expression in NK cells. Peripheral blood specimens were obtained from 40 RA patients and 20 healthy subjects. NK c...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Maryam Hemmatzadeh Elham Ahangar Parvin Alireza Ghanavatinejad Narges Rostami Mehrzad Hajaliloo Navid Shomali Hamed Mohammadi Farhad Jadidi-Niaragh Source Type: research
Importance of STAT3 Polymorphisms on the Risk and Clinical Characteristics of Rheumatoid Arthritis
In this study, we intended to evaluate the association of two miRSNPs with the risk of RA development and its clinical features. We studied 120 Iranian patients with RA and 125 non-RA subjects as controls. The genotypes and alleles of rs1053005 and rs1053023 in each individual were assessed by the high-resolution melting method. The distribution of STAT3 variants did not differ markedly in RA patients compared to healthy controls. Stratification analysis revealed that rs1053005 was linked with a higher concentration of C-reactive protein and an increased erythrocyte sedimentation rate, two indicators of inflammation and di...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Amirhossein Salehi Ebrahim Hazrati Hamta Ranjbar Javad Behroozi Bahram Pakzad Maryam Mousavi Mojtaba Mousavi Marzieh Hossein Balam Mansour Salesi Source Type: research
Identification of New Potential Allergens from Green-lipped Mussel (Perna Canaliculus)
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):711-715. doi: 10.18502/ijaai.v21i6.11532.ABSTRACTThe green-lipped mussel (Perna canaliculus) originates from New Zealand. To preserve the health benefits of green-lipped mussel meat, it is freeze-dried to make a long-lasting powder. The powder is used to treat arthritis because of its potential anti-inflammatory properties. The report describes a 54-year-old woman who developed immediate rhinoconjunctival and respiratory symptoms after inhaling green-lipped mussel powder she gave to her dog for arthritis. A skin prick test with green-lipped mussel powder was performed. Prote...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Paula Kage Kristin Schubert Regina Treudler Jan-Christoph Simon Martin Von Bergen Janina Tomm Source Type: research
