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Condition: Arthritis
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Identification of New Potential Allergens from Green-lipped Mussel (Perna Canaliculus)
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):711-715. doi: 10.18502/ijaai.v21i6.11532.ABSTRACTThe green-lipped mussel (Perna canaliculus) originates from New Zealand. To preserve the health benefits of green-lipped mussel meat, it is freeze-dried to make a long-lasting powder. The powder is used to treat arthritis because of its potential anti-inflammatory properties. The report describes a 54-year-old woman who developed immediate rhinoconjunctival and respiratory symptoms after inhaling green-lipped mussel powder she gave to her dog for arthritis. A skin prick test with green-lipped mussel powder was performed. Prote...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Paula Kage Kristin Schubert Regina Treudler Jan-Christoph Simon Martin Von Bergen Janina Tomm Source Type: research
MicroRNAs Targeting Programmed Cell Death Protein 1 (PD-1) Promote Natural Killer Cell Exhaustion in Rheumatoid Arthritis
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):646-656. doi: 10.18502/ijaai.v21i6.11524.ABSTRACT Natural killer (NK) cells play a role in the pathogenesis of rheumatoid arthritis (RA). Upregulated levels of programmed cell death protein 1 (PD-1) is a sign of exhausted NK cells that could be regulated by microRNAs (miRNAs). In this investigation, we determined PD‑1 expression on NK cells (as a representation of NK cell exhaustion) in RA patients and evaluated if miRNAs are involved in the modulation of PD-1 expression in NK cells. Peripheral blood specimens were obtained from 40 RA patients and 20 healthy subjects. NK c...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Maryam Hemmatzadeh Elham Ahangar Parvin Alireza Ghanavatinejad Narges Rostami Mehrzad Hajaliloo Navid Shomali Hamed Mohammadi Farhad Jadidi-Niaragh Source Type: research
Importance of STAT3 Polymorphisms on the Risk and Clinical Characteristics of Rheumatoid Arthritis
In this study, we intended to evaluate the association of two miRSNPs with the risk of RA development and its clinical features. We studied 120 Iranian patients with RA and 125 non-RA subjects as controls. The genotypes and alleles of rs1053005 and rs1053023 in each individual were assessed by the high-resolution melting method. The distribution of STAT3 variants did not differ markedly in RA patients compared to healthy controls. Stratification analysis revealed that rs1053005 was linked with a higher concentration of C-reactive protein and an increased erythrocyte sedimentation rate, two indicators of inflammation and di...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Amirhossein Salehi Ebrahim Hazrati Hamta Ranjbar Javad Behroozi Bahram Pakzad Maryam Mousavi Mojtaba Mousavi Marzieh Hossein Balam Mansour Salesi Source Type: research
Identification of New Potential Allergens from Green-lipped Mussel (Perna Canaliculus)
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):711-715. doi: 10.18502/ijaai.v21i6.11532.ABSTRACTThe green-lipped mussel (Perna canaliculus) originates from New Zealand. To preserve the health benefits of green-lipped mussel meat, it is freeze-dried to make a long-lasting powder. The powder is used to treat arthritis because of its potential anti-inflammatory properties. The report describes a 54-year-old woman who developed immediate rhinoconjunctival and respiratory symptoms after inhaling green-lipped mussel powder she gave to her dog for arthritis. A skin prick test with green-lipped mussel powder was performed. Prote...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Paula Kage Kristin Schubert Regina Treudler Jan-Christoph Simon Martin Von Bergen Janina Tomm Source Type: research
MicroRNAs Targeting Programmed Cell Death Protein 1 (PD-1) Promote Natural Killer Cell Exhaustion in Rheumatoid Arthritis
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):646-656. doi: 10.18502/ijaai.v21i6.11524.ABSTRACT Natural killer (NK) cells play a role in the pathogenesis of rheumatoid arthritis (RA). Upregulated levels of programmed cell death protein 1 (PD-1) is a sign of exhausted NK cells that could be regulated by microRNAs (miRNAs). In this investigation, we determined PD‑1 expression on NK cells (as a representation of NK cell exhaustion) in RA patients and evaluated if miRNAs are involved in the modulation of PD-1 expression in NK cells. Peripheral blood specimens were obtained from 40 RA patients and 20 healthy subjects. NK c...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Maryam Hemmatzadeh Elham Ahangar Parvin Alireza Ghanavatinejad Narges Rostami Mehrzad Hajaliloo Navid Shomali Hamed Mohammadi Farhad Jadidi-Niaragh Source Type: research
Importance of STAT3 Polymorphisms on the Risk and Clinical Characteristics of Rheumatoid Arthritis
In this study, we intended to evaluate the association of two miRSNPs with the risk of RA development and its clinical features. We studied 120 Iranian patients with RA and 125 non-RA subjects as controls. The genotypes and alleles of rs1053005 and rs1053023 in each individual were assessed by the high-resolution melting method. The distribution of STAT3 variants did not differ markedly in RA patients compared to healthy controls. Stratification analysis revealed that rs1053005 was linked with a higher concentration of C-reactive protein and an increased erythrocyte sedimentation rate, two indicators of inflammation and di...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Amirhossein Salehi Ebrahim Hazrati Hamta Ranjbar Javad Behroozi Bahram Pakzad Maryam Mousavi Mojtaba Mousavi Marzieh Hossein Balam Mansour Salesi Source Type: research
Identification of New Potential Allergens from Green-lipped Mussel (Perna Canaliculus)
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):711-715. doi: 10.18502/ijaai.v21i6.11532.ABSTRACTThe green-lipped mussel (Perna canaliculus) originates from New Zealand. To preserve the health benefits of green-lipped mussel meat, it is freeze-dried to make a long-lasting powder. The powder is used to treat arthritis because of its potential anti-inflammatory properties. The report describes a 54-year-old woman who developed immediate rhinoconjunctival and respiratory symptoms after inhaling green-lipped mussel powder she gave to her dog for arthritis. A skin prick test with green-lipped mussel powder was performed. Prote...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Paula Kage Kristin Schubert Regina Treudler Jan-Christoph Simon Martin Von Bergen Janina Tomm Source Type: research
MicroRNAs Targeting Programmed Cell Death Protein 1 (PD-1) Promote Natural Killer Cell Exhaustion in Rheumatoid Arthritis
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):646-656. doi: 10.18502/ijaai.v21i6.11524.ABSTRACT Natural killer (NK) cells play a role in the pathogenesis of rheumatoid arthritis (RA). Upregulated levels of programmed cell death protein 1 (PD-1) is a sign of exhausted NK cells that could be regulated by microRNAs (miRNAs). In this investigation, we determined PD‑1 expression on NK cells (as a representation of NK cell exhaustion) in RA patients and evaluated if miRNAs are involved in the modulation of PD-1 expression in NK cells. Peripheral blood specimens were obtained from 40 RA patients and 20 healthy subjects. NK c...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Maryam Hemmatzadeh Elham Ahangar Parvin Alireza Ghanavatinejad Narges Rostami Mehrzad Hajaliloo Navid Shomali Hamed Mohammadi Farhad Jadidi-Niaragh Source Type: research
Importance of STAT3 Polymorphisms on the Risk and Clinical Characteristics of Rheumatoid Arthritis
In this study, we intended to evaluate the association of two miRSNPs with the risk of RA development and its clinical features. We studied 120 Iranian patients with RA and 125 non-RA subjects as controls. The genotypes and alleles of rs1053005 and rs1053023 in each individual were assessed by the high-resolution melting method. The distribution of STAT3 variants did not differ markedly in RA patients compared to healthy controls. Stratification analysis revealed that rs1053005 was linked with a higher concentration of C-reactive protein and an increased erythrocyte sedimentation rate, two indicators of inflammation and di...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Amirhossein Salehi Ebrahim Hazrati Hamta Ranjbar Javad Behroozi Bahram Pakzad Maryam Mousavi Mojtaba Mousavi Marzieh Hossein Balam Mansour Salesi Source Type: research
Identification of New Potential Allergens from Green-lipped Mussel (Perna Canaliculus)
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):711-715. doi: 10.18502/ijaai.v21i6.11532.ABSTRACTThe green-lipped mussel (Perna canaliculus) originates from New Zealand. To preserve the health benefits of green-lipped mussel meat, it is freeze-dried to make a long-lasting powder. The powder is used to treat arthritis because of its potential anti-inflammatory properties. The report describes a 54-year-old woman who developed immediate rhinoconjunctival and respiratory symptoms after inhaling green-lipped mussel powder she gave to her dog for arthritis. A skin prick test with green-lipped mussel powder was performed. Prote...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Paula Kage Kristin Schubert Regina Treudler Jan-Christoph Simon Martin Von Bergen Janina Tomm Source Type: research
MicroRNAs Targeting Programmed Cell Death Protein 1 (PD-1) Promote Natural Killer Cell Exhaustion in Rheumatoid Arthritis
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):646-656. doi: 10.18502/ijaai.v21i6.11524.ABSTRACT Natural killer (NK) cells play a role in the pathogenesis of rheumatoid arthritis (RA). Upregulated levels of programmed cell death protein 1 (PD-1) is a sign of exhausted NK cells that could be regulated by microRNAs (miRNAs). In this investigation, we determined PD‑1 expression on NK cells (as a representation of NK cell exhaustion) in RA patients and evaluated if miRNAs are involved in the modulation of PD-1 expression in NK cells. Peripheral blood specimens were obtained from 40 RA patients and 20 healthy subjects. NK c...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Maryam Hemmatzadeh Elham Ahangar Parvin Alireza Ghanavatinejad Narges Rostami Mehrzad Hajaliloo Navid Shomali Hamed Mohammadi Farhad Jadidi-Niaragh Source Type: research
Importance of STAT3 Polymorphisms on the Risk and Clinical Characteristics of Rheumatoid Arthritis
In this study, we intended to evaluate the association of two miRSNPs with the risk of RA development and its clinical features. We studied 120 Iranian patients with RA and 125 non-RA subjects as controls. The genotypes and alleles of rs1053005 and rs1053023 in each individual were assessed by the high-resolution melting method. The distribution of STAT3 variants did not differ markedly in RA patients compared to healthy controls. Stratification analysis revealed that rs1053005 was linked with a higher concentration of C-reactive protein and an increased erythrocyte sedimentation rate, two indicators of inflammation and di...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Amirhossein Salehi Ebrahim Hazrati Hamta Ranjbar Javad Behroozi Bahram Pakzad Maryam Mousavi Mojtaba Mousavi Marzieh Hossein Balam Mansour Salesi Source Type: research
MicroRNAs Targeting Programmed Cell Death Protein 1 (PD-1) Promote Natural Killer Cell Exhaustion in Rheumatoid Arthritis
Iran J Allergy Asthma Immunol. 2022 Dec 24;21(6):646-656. doi: 10.18502/ijaai.v21i6.11524.ABSTRACT Natural killer (NK) cells play a role in the pathogenesis of rheumatoid arthritis (RA). Upregulated levels of programmed cell death protein 1 (PD-1) is a sign of exhausted NK cells that could be regulated by microRNAs (miRNAs). In this investigation, we determined PD‑1 expression on NK cells (as a representation of NK cell exhaustion) in RA patients and evaluated if miRNAs are involved in the modulation of PD-1 expression in NK cells. Peripheral blood specimens were obtained from 40 RA patients and 20 healthy subjects. NK c...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Maryam Hemmatzadeh Elham Ahangar Parvin Alireza Ghanavatinejad Narges Rostami Mehrzad Hajaliloo Navid Shomali Hamed Mohammadi Farhad Jadidi-Niaragh Source Type: research
Importance of STAT3 Polymorphisms on the Risk and Clinical Characteristics of Rheumatoid Arthritis
In this study, we intended to evaluate the association of two miRSNPs with the risk of RA development and its clinical features. We studied 120 Iranian patients with RA and 125 non-RA subjects as controls. The genotypes and alleles of rs1053005 and rs1053023 in each individual were assessed by the high-resolution melting method. The distribution of STAT3 variants did not differ markedly in RA patients compared to healthy controls. Stratification analysis revealed that rs1053005 was linked with a higher concentration of C-reactive protein and an increased erythrocyte sedimentation rate, two indicators of inflammation and di...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 14, 2023 Category: Allergy & Immunology Authors: Amirhossein Salehi Ebrahim Hazrati Hamta Ranjbar Javad Behroozi Bahram Pakzad Maryam Mousavi Mojtaba Mousavi Marzieh Hossein Balam Mansour Salesi Source Type: research
