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Condition: Arthritis
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Total 2071 results found since Jan 2013.
Perspectives on Mycophenolate Mofetil in the Management of Autoimmunity
Clin Rev Allergy Immunol. 2023 Jun 20. doi: 10.1007/s12016-023-08963-3. Online ahead of print.ABSTRACTBefore becoming a cornerstone in the treatment of numerous immune-mediated diseases, mycophenolate mofetil (MMF) was first introduced as an immunosuppressive agent in transplant immunology and later received the attention of rheumatologists and clinicians involved in the management of autoimmune diseases. MMF is now a widespread immunosuppressive drug for the treatment of several conditions, including lupus nephritis, interstitial lung disease associated with systemic sclerosis, and anti-neutrophil cytoplasm antibody (ANCA...
Source: Clinical Lung Cancer - June 20, 2023 Category: Cancer & Oncology Authors: Rithika Bhat Antonio Tonutti Suraj Timilsina Carlo Selmi M Eric Gershwin Source Type: research
Correspondence on "Associations of baseline use of biologic or targeted synthetic DMARDs with COVID-19 severity in rheumatoid arthritis: results from the COVID-19 Global Rheumatology Alliance physician registry" by Sparks et al
We read with great interest the Global Rheumatology Alliance report on COVID-19 on biologic or targeted synthetic disease-modifying antirheumatic drugs (DMARDs) in rheumatoid arthritis (RA).1 The first important result of the registry database is that B-cell depletion, by compromising the primary antibody response, increases the severity of infected patients. Considering the critical role of B cells in the adaptive immune response, this sounds quite correct.2 Even the data on interleukin 6 and tumour necrosis factor (TNF) inhibitors appear quite understandable considering the systemic inflammation raised by SARS-CoV-2 infe...
Source: Annals of the Rheumatic Diseases - June 12, 2023 Category: Rheumatology Authors: Gremese, E., Ferraccioli, G. Tags: ARD, COVID-19 Correspondence Source Type: research
Anti-inflammatory Effects of First-line Anti-arthritic Drugs on T-cell Activation
Source: Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry - June 8, 2023 Category: Allergy & Immunology Authors: Manolios, Nicholas Hou, Guojiang Tags: Research article Source Type: research
Handmade spacers for two-stage exchange at the hip
This article describes a simple and safe technique for handmade spacers at the hip.INDICATION: Periprosthetic joint infection of the hip. Septic arthritis of the native joint.CONTRAINDICATIONS: Known allergy against components of polymethylmethacrylate bone cements. Inadequate compliance for two-stage exchange. Patient unfit to undergo two-stage exchange. Bony defect situation at the acetabulum impeding stable reduction of the spacer. Bone loss at the femur jeopardizing stable fixation of the stem. Soft tissue damage with need for plastic temporary vacuum-assisted wound closure (VAC) therapy.SURGICAL TECHNIQUE: Tailoring b...
Source: Operative Orthopadie und Traumatologie - May 13, 2023 Category: Orthopaedics Authors: Sebastian von Hertzberg-B ölch Martin Luedemann Jan Oberfeld Axel Jakuscheit Maximilian Rudert Source Type: research
