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Total 564 results found since Jan 2013.

Phenotypes of persistent hen`s egg allergy in children and adolescents
CONCLUSIONS: Persistent hen`s egg allergy is characterized by multiple food allergies and age-related multimorbidities. Baked egg and heated egg yolk tolerance were more likely to be considered in a subgroup with a high expectation for finding a way to eliminate their allergy.PMID:36866980 | DOI:10.24953/turkjped.2021.5417
Source: The Turkish Journal of Pediatrics - March 3, 2023 Category: Pediatrics Authors: Hilal Ünsal Sevda T üten Dal Ay şegül Akarsu Ümit Murat Şahiner Özge Soyer B ülent Enis Şekerel Source Type: research

Peanut-Allergic Kids With Other Food Allergies, Eczema See Responses With EPIT
(MedPage Today) -- SAN ANTONIO -- Epicutaneous immunotherapy (EPIT) administered through an investigational skin patch over 12 months led to more responses -- with favorable safety -- compared with placebo in peanut-allergic toddlers with...
Source: MedPage Today Pediatrics - February 28, 2023 Category: Pediatrics Source Type: news

School lives of adolescent school students living with chronic physical health conditions: a qualitative evidence synthesis
Conclusions Thematic synthesis highlighted the commonalities, rather than divergence, of issues for young people across different chronic conditions. Policies need to be based on the experiences of the people they aim to provide for, and while attendance and attainment remain important, there is clearly more that needs to be considered when gathering data, designing interventions and developing policies to support this population. It may also be advisable for clinical professionals to include the broader psychosocial aspects of school life in discussions and plans to support young people with long-term conditions. PROSPER...
Source: Archives of Disease in Childhood - February 17, 2023 Category: Pediatrics Authors: Spencer, B. K. C., Wright, J., Flemming, K., Cottrell, D., Pini, S. Tags: Open access Original research Source Type: research

Association of food allergy in children with vitamin D insufficiency: a systematic review and meta-analysis
Conclusion: Decreased maternal vitamin D levels and infant vitamin D insufficiency appear to increase the incidence of food allergies, particularly in the second year of life. To confirm this association, multicenter longitudinal studies are required.What is Known:• In newborns and young children, vitamin D deficiency and insufficiency are prevalent.• The exact role of vitamin D in atopic diseases remains controversial.What is New:• Decreased maternal vitamin D levels and infant vitamin D insufficiency appear to increase the incidence of food allergies. This association is more evident in the second year of life.
Source: European Journal of Pediatrics - February 15, 2023 Category: Pediatrics Source Type: research

How Good is Cholecystectomy For Biliary Dyskinesia in Pediatric Patients?
Discussion Biliary disease includes gallstones, cholecystitis (inflammation of the gallbladder), cholangiopathy and cholangitis (pathology of the bile ducts), biliary dyskinesia, gangrene, and cancer. Some are often overlapping as gallstones often contributing to cholecystitis and cholangitis. Biliary dyskinesia (BD) is well-recognized in adults. Adult criteria include: “abdominal pain located in the epigastrium and/or right upper quadrant along with; buildup of pain to a steady level and lasting 30 minutes or longer, pain occurring at different intervals and not daily, severe enough to interrupt activities or lead t...
Source: PediatricEducation.org - January 30, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

An ulcerated lesion in a previously well child
A previously well 6-year-old girl was referred to clinic with a 5-month history of an ulcerated lesion on her left forearm after sustaining an insect bite in Iraq, having recently emigrated to the UK. The lesion was initially painful and later became ulcerated, pruritic and inflamed. She previously received treatment with topical corticosteroid with no improvement. There were no systemic symptoms of fever, weight loss or night sweats. She had no significant medical history, no allergies or regular medication. Her vaccinations were up to date including BCG. There was no known exposure to tuberculosis and no other family mem...
Source: Archives of Disease in Childhood - Education and Practice - January 19, 2023 Category: Pediatrics Authors: Mulholland, M., Glancy, C., Sweeney, E., Surgenor, L., Hunter, H., Walker, S., Christie, S., Mallett, P. Tags: Epilogue Source Type: research

Food intolerances in children and adolescents in Switzerland
Conclusions: Clinicians should be aware of the high frequency of food avoidance in the pediatric population due to true intolerance, functional diseases, or due to lifestyle reasons. Milk is the most avoided food and half of the affected patients avoid foods without guidance by professional dieticians, therefore risking possible negative impacts on their physical and mental health. Pediatricians should perform further investigations or advise nutritional guidance if an avoidance of foods or specific diets occurs.What is Known:• The prevalence of food intolerances in children and adolescents is unknown.• Eating behavior...
Source: European Journal of Pediatrics - December 13, 2022 Category: Pediatrics Source Type: research

Skin Patch Helped Young Kids With Peanut Allergies
(MedPage Today) -- LOUISVILLE, Ky. -- Epicutaneous immunotherapy administered through a patch applied to the skin (VP250) led to better responses compared with placebo for peanut allergies in toddlers, the phase III randomized EPITOPE study showed...
Source: MedPage Today Pediatrics - November 15, 2022 Category: Pediatrics Source Type: news

Psychiatric comorbidities in children and adolescents with chronic urticaria
CONCLUSIONS: The included studies suggest an increased incidence of psychopathology among children and adolescents with CU as opposed to healthy age-matched individuals, but the data are scarce. Further research is required to clarify whether psychopathology is just a comorbid entity, the cause, or the consequence of CU. Meanwhile an interdisciplinary collaboration between allergists/dermatologists and psychiatrists is expected to substantially minimize CU burden and improve patients' quality of life.PMID:36376557 | DOI:10.1007/s12519-022-00641-2
Source: World Journal of Pediatrics : WJP - November 14, 2022 Category: Pediatrics Authors: George N Konstantinou Gerasimos N Konstantinou Source Type: research

Advances in immunoglobulin E mediated antibiotic allergy
Purpose of review The purpose of this review is to identify recent advances in our understanding and management of immunoglobulin E (IgE)-mediated antibiotic allergy. Recent findings Antibiotics remain a leading cause of fatal anaphylaxis reported to the FDA. However, recent advances have defined the features of adult and pediatric patients without true IgE-mediated allergy or any mechanism of anaphylaxis when tested. This has created opportunities to use direct challenges to disprove these allergies at the point-of-care and improves antibiotic stewardship. Additional advances have highlighted cross-reactive str...
Source: Current Opinion in Pediatrics - November 7, 2022 Category: Pediatrics Tags: ALLERGY, IMMUNOLOGY AND RELATED DISORDERS: Edited by Jordan S. Orange Source Type: research

Benefits of dietary fibre for children in health and disease
Fibre is an essential nutrient in the human diet that is crucial for human health. It provides a range of functional benefits, including stool bulking, and physiological benefits through fermentation of diverse fibre types by the gut microbiome including cholesterol lowering, glycaemic control and weight control. The by-products of the fermentation of fibre in the gut confer health benefits that extend beyond the gut to the immune system and organs such as the liver, kidneys and the brain. A lack of fibre in the diet has been associated with several disorders in children including constipation, irritable bowel syndrome, al...
Source: Archives of Disease in Childhood - October 19, 2022 Category: Pediatrics Authors: Hojsak, I., Benninga, M. A., Hauser, B., Kansu, A., Kelly, V. B., Stephen, A. M., Morais Lopez, A., Slavin, J., Tuohy, K. Tags: Open access Review Source Type: research

Multi-omic factors associated with future wheezing in infants
CONCLUSIONS: Host-microbiome interactions in saliva may yield pathophysiologic clues about the origins of wheezing and aid identification of infants at risk of future wheezing episodes.IMPACT: Wheezing is multi-factorial, but the relative contributions of infant traits, environment, and underlying biology are poorly understood. This multi-omic study identifies three molecular factors, including salivary microRNAs, microbes, and viral phages associated with increased risk of infant wheezing. Measurement of these molecular factors enhanced predictive accuracy for future wheezing when combined with family asthma history and d...
Source: Pediatric Research - September 27, 2022 Category: Pediatrics Authors: Ramin Beheshti E Scott Halstead Daniel McKeone Steven D Hicks Source Type: research