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Specialty: Allergy & Immunology
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Total 5477 results found since Jan 2013.
Early Life Exposure to Human Milk Oligosaccharides Reduces Allergic Response in a Murine Asthma Model
CONCLUSION: We propose a model in which orally administered HMOs delivered during early life shift the microbiota toward increased production of SCFAs, which dampens the allergic immune responses behind allergy and asthma. Overall, these data suggest the potential for HMO supplementation to protect infants against asthma development later in life, with possible benefits against additional atopic diseases such as eczema and food allergies.PMID:37545544 | PMC:PMC10404156 | DOI:10.1155/2023/9603576
Source: Journal of Immunology Research - August 7, 2023 Category: Allergy & Immunology Authors: Tahereh Bozorgmehr Rozlyn C T Boutin Sarah E Woodward Katherine Donald Jo May Chow Rachael H Buck B Brett Finlay Source Type: research
Drug Allergy in Older Adults: A Study from the United States Drug Allergy Registry
Older adults have an increased risk of adverse drug reactions and negative effects associated with alternative antibiotic use. Although number of antibiotic allergies reported increases with age, the characteristics and outcomes of older adults receiving drug allergy assessment are unknown.
Source: Annals of Allergy, Asthma and Immunology - August 7, 2023 Category: Allergy & Immunology Authors: John J.O. Accarino, Allison Ramsey, Upeka Samarakoon, Elizabeth Phillips, Alexei Gonzalez-Estrada, Iris M. Otani, Xiaoqing Fu, Aleena Banerji, Cosby A. Stone, David A. Khan, Kimberly G. Blumenthal, the USDAR Study Team Tags: Original Article Source Type: research
Maternal vitamin D –related metabolome and offspring risk of asthma outcomes
Vitamin D deficiency in childhood has been associated with various adverse health consequences as 25-hydroxyvitamin D (25(OH)D) possesses a range of immune regulatory properties with potential implications for proneness to respiratory infection, allergies, and asthma.1,2 Studies have further shown that 25(OH)D deficiency during pregnancy may affect fetal immune programming, consequently increasing the risk of asthma in early childhood.3,4 Therefore, we recently performed an intervention study in the Copenhagen Prospective Studies on Asthma in Childhood 2010 (COPSAC2010) cohort,5 which showed beneficial effects of high-dose...
Source: Journal of Allergy and Clinical Immunology - August 7, 2023 Category: Allergy & Immunology Authors: Min Kim, Nicklas Brustad, Mina Ali, G özde Gürdeniz, Morten Arendt, Augusto A. Litonjua, Craig E. Wheelock, Rachel S. Kelly, Yulu Chen, Nicole Prince, Feng Guo, Xiaobo Zhou, Jakob Stokholm, Klaus Bønnelykke, Scott T. Weiss, Hans Bisgaard, Jessica Lasky Source Type: research
Drug allergy in older adults
Older adults have an increased risk of adverse drug reactions and negative effects associated with alternative antibiotic use. Although the number of antibiotic allergies reported increases with age, the characteristics and outcomes of older adults receiving drug allergy assessment are unknown.
Source: Annals of Allergy, Asthma and Immunology - August 7, 2023 Category: Allergy & Immunology Authors: John J.O. Accarino, Allison Ramsey, Upeka Samarakoon, Elizabeth Phillips, Alexei Gonzalez-Estrada, Iris M. Otani, Xiaoqing Fu, Aleena Banerji, Cosby A. Stone, David A. Khan, Kimberly G. Blumenthal, the United States Drug Allergy Registry Study Team Source Type: research
Anti-tumor activity of trimethoprim-sulfamethoxazole against melanoma skin cancer through triggering allergic reaction and promoting immunity
This study examined the potential roles of TMP-SMX in melanoma skin cancer using an immunodeficient mouse model. TMP-SMX significantly improved the survival rate and reduced the tumor weight and growth and vascular endothelial growth factor levels in melanoma skin cancer of immunodeficient mice. In the forced swimming test, TMP-SMX significantly reduced immobility time compared to the melanoma skin cancer of immunodeficient mice, indicating improved immunity. TMP-SMX significantly increased infiltration of mast cells and release of allergy-related mediators (IgE, histamine, interleukin (IL)-4, IL-5, IL-13, and IL-33) and i...
Source: International Immunopharmacology - August 3, 2023 Category: Allergy & Immunology Authors: Hee-Yun Kim Ho-Geun Kang Hyung-Min Kim Hyun-Ja Jeong Source Type: research
Allergies Come Clean: The Role of Detergents in Epithelial Barrier Dysfunction
The objective of this review is to examine the role of detergents as a potential risk factor for developing allergic disease.Recent FindingsHerein, we identify key sources of human detergent exposure. We summarize the evidence suggesting a possible role for detergents and related chemicals in initiating epithelial barrier dysfunction and allergic inflammation. We primarily focus on experimental models of atopic dermatitis, asthma, and eosinophilic esophagitis, which show compelling associations between allergic disease and detergent exposure. Mechanistic studies suggest that detergents disrupt epithelial barrier integrity ...
Source: Current Allergy and Asthma Reports - August 1, 2023 Category: Allergy & Immunology Source Type: research
The Effectiveness of Probiotics in Treating Food and Cow's Milk Allergies among Pediatric Age Group: A Meta-analysis of Randomized Controlled Trials
Iran J Allergy Asthma Immunol. 2023 Apr 30;22(2):124-137. doi: 10.18502/ijaai.v22i2.12674.ABSTRACTThe global prevalence of allergies is on the rise. Food allergies are of special concern among children under 5 years of age, leading to morbidity and mortality. Though the standard management is avoidance, probiotics are being used widely to prevent and treat food allergies. We aimed to determine the effect of probiotics as a therapeutic option for controlling food and cow's milk allergy among children under 5 years of age. A systematic search of electronic medical literature databases was conducted. We included all eligible ...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 27, 2023 Category: Allergy & Immunology Authors: Hua Feng Yongning Wu Source Type: research
Pediatric Allergic March Supported by Nationwide EHR Data
(MedPage Today) -- A typical allergic march started with atopic dermatitis during infancy and progressed to other allergies later in life, a multi-state study found.
In total, 13.4% of pediatric study participants had two or more allergic conditions...
Source: MedPage Today Allergy - July 27, 2023 Category: Allergy & Immunology Source Type: news
