Filtered By:
Therapy: Stem Cell Therapy
This page shows you your search results in order of date. This is page number 12.
Order by Relevance | Date
Total 54671 results found since Jan 2013.
The effects of melatonin on the viability and osteogenic/odontogenic differentiation of human stem cells from the apical papilla
CONCLUSIONS: Melatonin treatment enhanced osteogenic/odontogenic differentiation of hSCAPs with a dose dependent effect on cell viability.PMID:37715020 | DOI:10.1007/s11033-023-08747-0
Source: Molecular Biology Reports - September 15, 2023 Category: Molecular Biology Authors: Hamed Karkehabadi Roshanak Abbasi Rezvan Najafi Elham Khoshbin Source Type: research
Hypoxic Mesenchymal Stem Cells Promote Diabetic Wound Healing in Rats by Increasing VEGF Secretion
Biomed Environ Sci. 2023 Aug 20;36(8):756-759. doi: 10.3967/bes2023.100.NO ABSTRACTPMID:37711087 | DOI:10.3967/bes2023.100
Source: Biomedical and Environmental Sciences : BES - September 15, 2023 Category: Biomedical Science Authors: Su Jing Zhuang Xu Yan Sun Meng Luo Zhong Wang Xue Juan Zhang Zong Sheng Gao Jian Liu Xin Ran Liu Shi Ze Liu Xiao Peng Jia Source Type: research
Key role of exosomes derived from M2 macrophages in maintaining cancer cell stemness (Review)
Int J Oncol. 2023 Nov;63(5):126. doi: 10.3892/ijo.2023.5574. Epub 2023 Sep 15.ABSTRACTCancer stem cells (CSCs) constitute a specific subset of cells found within tumors that are responsible for initiating, advancing and resisting traditional cancer treatments. M2 macrophages, also known as alternatively activated macrophages, contribute to the development and progression of cancer through their involvement in promoting angiogenesis, suppressing the immune system, supporting tumor growth and facilitating metastasis. Exosomes, tiny vesicles released by cells, play a crucial role in intercellular communications and have been ...
Source: International Journal of Oncology - September 15, 2023 Category: Cancer & Oncology Authors: Weiqiong Zhang Ruiping Zhou Xin Liu Lin You Chang Chen Xiaoling Ye Jie Liu Youde Liang Source Type: research
Acute Myeloid Leukemia Causes T Cell Exhaustion and Depletion in a Humanized Graft-versus-Leukemia Model
J Immunol. 2023 Sep 15:ji2300111. doi: 10.4049/jimmunol.2300111. Online ahead of print.ABSTRACTAllogeneic hematopoietic stem cell transplantation (alloSCT) is, in many clinical settings, the only curative treatment for acute myeloid leukemia (AML). The clinical benefit of alloSCT greatly relies on the graft-versus-leukemia (GVL) effect. However, AML relapse remains the top cause of posttransplant death; this highlights the urgent need to enhance GVL. Studies of human GVL have been hindered by the lack of optimal clinically relevant models. In this article, we report, the successful establishment of a novel (to our knowledg...
Source: Journal of Immunology - September 15, 2023 Category: Allergy & Immunology Authors: Bei Jia Chenchen Zhao Kentaro Minagawa Hiroko Shike David F Claxton W Christopher Ehmann Witold B Rybka Shin Mineishi Ming Wang Todd D Schell K Sandeep Prabhu Robert F Paulson Yi Zhang Leonard D Shultz Hong Zheng Source Type: research
The effects of melatonin on the viability and osteogenic/odontogenic differentiation of human stem cells from the apical papilla
CONCLUSIONS: Melatonin treatment enhanced osteogenic/odontogenic differentiation of hSCAPs with a dose dependent effect on cell viability.PMID:37715020 | DOI:10.1007/s11033-023-08747-0
Source: Molecular Biology Reports - September 15, 2023 Category: Molecular Biology Authors: Hamed Karkehabadi Roshanak Abbasi Rezvan Najafi Elham Khoshbin Source Type: research
Elimination of CaMKII δ Autophosphorylation by CRISPR-Cas9 Base Editing Improves Survival and Cardiac Function in Heart Failure in Mice
CONCLUSIONS: Ablation of CaMKIIδ autophosphorylation by adenine base editing may offer a potential broad-based therapeutic concept for human cardiac disease.PMID:37712250 | DOI:10.1161/CIRCULATIONAHA.123.065117
Source: Circulation - September 15, 2023 Category: Cardiology Authors: Simon Lebek Xurde M Caravia Francesco Chemello Wei Tan John R McAnally Kenian Chen Lin Xu Ning Liu Rhonda Bassel-Duby Eric N Olson Source Type: research
Hypoxic Mesenchymal Stem Cells Promote Diabetic Wound Healing in Rats by Increasing VEGF Secretion
Biomed Environ Sci. 2023 Aug 20;36(8):756-759. doi: 10.3967/bes2023.100.NO ABSTRACTPMID:37711087 | DOI:10.3967/bes2023.100
Source: Biomedical and Environmental Sciences : BES - September 15, 2023 Category: Biomedical Science Authors: Su Jing Zhuang Xu Yan Sun Meng Luo Zhong Wang Xue Juan Zhang Zong Sheng Gao Jian Liu Xin Ran Liu Shi Ze Liu Xiao Peng Jia Source Type: research
Surface modification strategies in translocating nano-vesicles across different barriers and the role of bio-vesicles in improving anticancer therapy
J Control Release. 2023 Sep 13:S0168-3659(23)00603-X. doi: 10.1016/j.jconrel.2023.09.016. Online ahead of print.ABSTRACTNanovesicles and bio-vesicles (BVs) have emerged as promising tools to achieve targeted cancer therapy due to their ability to overcome many of the key challenges currently being faced with conventional chemotherapy. These challenges include the diverse and often complex pathophysiology involving the progression of cancer, as well as the various biological barriers that circumvent therapeutic molecules reaching their target site in optimum concentration. The scientific evidence suggests that surface-funct...
Source: Cancer Control - September 15, 2023 Category: Cancer & Oncology Authors: Pratiksha Tiwari Krishna Yadav Ravi Prakash Shukla Shalini Gautam Disha Marwaha Madhu Sharma Prabhat Ranjan Mishra Source Type: research
Cis-regulatory arbitrators of regeneration
Cell Stem Cell. 2023 Sep 6:S1934-5909(23)00295-3. doi: 10.1016/j.stem.2023.08.012. Online ahead of print.ABSTRACTMammals favor healing with scaring over functional tissue regeneration.1 In this issue of Cell Stem Cell, Mack et al. use "super-healer" mice to identify cis-regulatory variations that direct regenerative versus fibrotic gene expression in wound fibroblasts and they uncover complement factor H as a molecular driver of skin regeneration.2.PMID:37714155 | DOI:10.1016/j.stem.2023.08.012
Source: Cell Stem Cell - September 15, 2023 Category: Stem Cells Authors: Piotr Konieczny Shruti Naik Source Type: research
Allele-specific expression reveals genetic drivers of tissue regeneration in mice
Cell Stem Cell. 2023 Sep 13:S1934-5909(23)00293-X. doi: 10.1016/j.stem.2023.08.010. Online ahead of print.ABSTRACTIn adult mammals, skin wounds typically heal by scarring rather than through regeneration. In contrast, "super-healer" Murphy Roths Large (MRL) mice have the unusual ability to regenerate ear punch wounds; however, the molecular basis for this regeneration remains elusive. Here, in hybrid crosses between MRL and non-regenerating mice, we used allele-specific gene expression to identify cis-regulatory variation associated with ear regeneration. Analyzing three major cell populations (immune, fibroblast, and endo...
Source: Cell Stem Cell - September 15, 2023 Category: Stem Cells Authors: Katya L Mack Heather E Talbott Michelle F Griffin Jennifer B L Parker Nicholas J Guardino Amanda F Spielman Michael F Davitt Shamik Mascharak Mauricio Downer Annah Morgan Caleb Valencia Deena Akras Mark J Berger Derrick C Wan Hunter B Fraser Michael T Lon Source Type: research
Lipocalin 2 induces self-limited inhibition of osteoblast differentiation of mesenchymal stem cells
CONCLUSION: Lcn2 is essential for normal osteogenic differentiation of MSCs, but its overexpression and excessive secretion in aging induce self-limited inhibition of osteogenic differentiation of MSCs.PMID:37712270 | DOI:10.12122/j.issn.1673-4254.2023.08.10
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Z Chen S Li Y Zhang W Yang T Wang Source Type: research
Metformin inhibits self-renewal of colorectal cancer stem cells by inhibiting mitochondrial oxidative phosphorylation
CONCLUSION: Metformin reduces mitochondrial oxidative phosphorylation and ROS levels by inhibiting mitochondrial complex Ⅰ, thereby suppressing Wnt signaling pathway to reduce selfrenewal ability of colorectal CSCs.PMID:37712263 | DOI:10.12122/j.issn.1673-4254.2023.08.03
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: C Yan S Liu Q Song Y Hu Source Type: research
Secretome Derived from Mesenchymal Stem/Stromal Cells: A Promising Strategy for Diabetes and its Complications
Curr Stem Cell Res Ther. 2023 Sep 13. doi: 10.2174/1574888X19666230913154544. Online ahead of print.ABSTRACTDiabetes is a complex metabolic disease with a high global prevalence. The health and quality of life of patients with diabetes are threatened by many complications, including diabetic foot ulcers, diabetic kidney diseases, diabetic retinopathy, and diabetic peripheral neuropathy. The application of mesenchymal stem/stromal cells (MSCs) in cell therapies has been recognized as a potential treatment for diabetes and its complications. MSCs were originally thought to exert biological effects exclusively by differentiat...
Source: Current Stem Cell Research and Therapy - September 15, 2023 Category: Stem Cells Authors: Ling Li Siyu Hua Lianghui You Tianying Zhong Source Type: research
Comparative efficacy of endogenous stem cells recruiting hydrogels and stem cell-loaded hydrogels in knee cartilage regeneration: a meta-analysis
Conclusion The current study indicates that both endogenous stem cell recruiting hydrogels and stem cell loaded hydrogels can effectively promote knee joint cartilage regeneration in animal trials.PMID:37711133 | DOI:10.2174/1574888X19666230914123443
Source: Current Stem Cell Research and Therapy - September 15, 2023 Category: Stem Cells Authors: Wanyun Feng Chaohua Zhu Ruoxiang Miao Danni Li Xi Xiong Ruyu Wang Guobing Liu Jun Ma Source Type: research
Cancer Stem Cells in Carcinogenesis and Potential Role in Pancreatic Cancer
Curr Stem Cell Res Ther. 2023 Sep 14. doi: 10.2174/1574888X19666230914103420. Online ahead of print.ABSTRACTA poor prognosis is associated with pancreatic cancer because of resistance during treatment and early distant metastases. The discovery of cancer stem cells has opened up novel avenues for research into the biology and treatment of cancer. Many investigations have pointed out the role of these types of stem cells in the oncogenesis and progression of hematologic and solid malignancies, specifically. Due to the existence of cancer stem cells in the proliferation and preservation of pancreatic tumors, such malignancie...
Source: Current Stem Cell Research and Therapy - September 15, 2023 Category: Stem Cells Authors: Rishav Sharma Rishabha Malviya Source Type: research
