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Nutrition: Vitamin A
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Total 18962 results found since Jan 2013.
Characterization of micronutrient supplements use by Brazilian children 6-59 months of age: Brazilian National Survey on Child Nutrition (ENANI-2019)
This study aimed to characterize micronutrient supplements use among Brazilian children 6-59 months of age included in the Brazilian National Survey on Child Nutrition (ENANI-2019; n = 12,598). Micronutrient supplements use at the time of the interview and the 6 months prior to it was evaluated using a structured questionnaire. The following indicators were included: micronutrient supplement use; supplements containing a single micronutrient; supplements of the Brazilian National Iron Supplementation Program (PNSF); multivitamin supplements with or without minerals; multivitamin supplements with minerals; multivitamin supp...
Source: Cadernos de Saude Publica - August 30, 2023 Category: International Medicine & Public Health Authors: Maiara Brusco de Freitas In ês Rugani Ribeiro de Castro Raquel Machado Schincaglia Let ícia B Vertulli Carneiro Nadya Helena Alves-Santos Paula Normando Pedro Gomes Andrade Gilberto Kac Brazilian Consortium on Child Nutrition 5 Source Type: research
Corticosteroid implants for chronic non-infectious uveitis
CONCLUSIONS: Our confidence is limited that local corticosteroid implants are superior to sham therapy or standard-of-care therapy in reducing the risk of uveitis recurrence. We demonstrated different effectiveness on BCVA relative to comparators in people with non-infectious uveitis. Nevertheless, the evidence suggests that these implants may increase the risk of cataract progression and IOP elevation, which will require interventions over time. To better understand the efficacy and safety profiles of corticosteroid implants, we need future trials that examine implants of different doses, used for different durations. The...
Source: Cochrane Database of Systematic Reviews - August 29, 2023 Category: General Medicine Authors: Amit Reddy Su-Hsun Liu Christopher J Brady Pamela C Sieving Alan G Palestine Source Type: research
Systemic gene therapy rescues retinal dysfunction and hearing loss in a model of Norrie disease
EMBO Mol Med. 2023 Aug 29:e17393. doi: 10.15252/emmm.202317393. Online ahead of print.ABSTRACTDeafness affects 5% of the world's population, yet there is a lack of treatments to prevent hearing loss due to genetic causes. Norrie disease is a recessive X-linked disorder, caused by NDP gene mutation. It manifests as blindness at birth and progressive sensorineural hearing loss, leading to debilitating dual sensory deprivation. To develop a gene therapy, we used a Norrie disease mouse model (Ndptm1Wbrg ), which recapitulates abnormal retinal vascularisation and progressive hearing loss. We delivered human NDP cDNA by intraven...
Source: Molecular Medicine - August 29, 2023 Category: Molecular Biology Authors: Valda Pauzuolyte Aara Patel James R Wawrzynski Neil J Ingham Yeh Chwan Leong Rajvinder Karda Maria Bitner-Glindzicz Wolfgang Berger Simon N Waddington Karen P Steel Jane C Sowden Source Type: research
How the immune response to the structural proteins of SARS-CoV-2 affects the retinal vascular endothelial cells: an immune thrombotic and/or endotheliopathy process with in silico modeling
Immunol Res. 2023 Aug 29. doi: 10.1007/s12026-023-09412-1. Online ahead of print.ABSTRACTThrombotic events associated with SARS-CoV-2 at the vascular endothelium still remains unclear. The aim of the current study is to determine the relationship between cellular proteins on the (ocular) vascular endothelial surface and the immune thrombotic and/or endotheliopathy process elicited by SARS-CoV-2 using an in-silico modeling. The structural S (spike glycoprotein), N (nucleocapsid protein), M (membrane protein), and E (envelope protein) proteins, an accessory protein (ORF1ab) of SARS-CoV-2 and 158 cellular proteins associated ...
Source: Cell Research - August 29, 2023 Category: Cytology Authors: I şıl Kutlutürk Ecem Önder Tokuç Levent Karaba ş Ren é Rückert M ücahit Kaya Ali Karag öz Marion R Munk Source Type: research
Extrastriate activity reflects the absence of local retinal input
Conscious Cogn. 2023 Aug 26;114:103566. doi: 10.1016/j.concog.2023.103566. Online ahead of print.ABSTRACTThe physiological blind spot corresponds to the optic disc where the retina contains no light-detecting photoreceptor cells. Our perception seemingly fills in this gap in input. Here we suggest that rather than an active process, such perceptual filling-in could instead be a consequence of the integration of visual inputs at higher stages of processing discounting the local absence of retinal input. Using functional brain imaging, we resolved the retinotopic representation of the physiological blind spot in early human ...
Source: Consciousness and Cognition - August 28, 2023 Category: Neurology Authors: Poutasi W B Urale Lydia Zhu Roberta Gough Derek Arnold Dietrich Samuel Schwarzkopf Source Type: research
Bilateral sequential and simultaneous rhegmatogenous retinal detachments: anatomic and functional outcomes
CONCLUSIONS: SSAS was similar for both eyes. The subsequent eye was more likely to be treated earlier with less advanced presentations, but at 3 months, PHVA was not significantly different between eyes. Difference in final PHVA may be attributable to longer follow-up in first eyes.PMID:37640227 | DOI:10.1016/j.jcjo.2023.07.022
Source: Canadian Journal of Ophthalmology - August 28, 2023 Category: Opthalmology Authors: Sihame Doukkali M élanie Hébert Eunice You Serge Bourgault Mathieu Caissie Éric Tourville Ali Dirani Source Type: research
Extrastriate activity reflects the absence of local retinal input
Conscious Cogn. 2023 Aug 26;114:103566. doi: 10.1016/j.concog.2023.103566. Online ahead of print.ABSTRACTThe physiological blind spot corresponds to the optic disc where the retina contains no light-detecting photoreceptor cells. Our perception seemingly fills in this gap in input. Here we suggest that rather than an active process, such perceptual filling-in could instead be a consequence of the integration of visual inputs at higher stages of processing discounting the local absence of retinal input. Using functional brain imaging, we resolved the retinotopic representation of the physiological blind spot in early human ...
Source: Consciousness and Cognition - August 28, 2023 Category: Neurology Authors: Poutasi W B Urale Lydia Zhu Roberta Gough Derek Arnold Dietrich Samuel Schwarzkopf Source Type: research
Bilateral sequential and simultaneous rhegmatogenous retinal detachments: anatomic and functional outcomes
CONCLUSIONS: SSAS was similar for both eyes. The subsequent eye was more likely to be treated earlier with less advanced presentations, but at 3 months, PHVA was not significantly different between eyes. Difference in final PHVA may be attributable to longer follow-up in first eyes.PMID:37640227 | DOI:10.1016/j.jcjo.2023.07.022
Source: Canadian Journal of Ophthalmology - August 28, 2023 Category: Opthalmology Authors: Sihame Doukkali M élanie Hébert Eunice You Serge Bourgault Mathieu Caissie Éric Tourville Ali Dirani Source Type: research
Outcomes and risk factors for Kahook Dual Blade excisional goniotomy with concomitant phacoemulsification: A multicentre Canadian study
CONCLUSION: This multicentre Canadian study provides real-world data that support the safety and efficacy of phaco-KDB in reducing IOP and AGM use with no evidence of disease progression during the follow-up period.PMID:37634551 | DOI:10.1016/j.jcjo.2023.08.004
Source: Canadian Journal of Ophthalmology - August 27, 2023 Category: Opthalmology Authors: Ali Salimi Oscar Kasner Steven Schendel Marc Mydlarski Dima Kalache Lautaro Vera Rob Pintwala Paul Harasymowycz Source Type: research
Trimethylated chitosan-coated flexible liposomes with resveratrol for topical drug delivery to reduce blue-light-induced retinal damage
In this study, we developed flexible liposomes based on trimethylated chitosan (TMC-Lipo) to deliver resveratrol for the treatment of retinal diseases. Flexible liposomes can easily cross various biological barriers. Chitosan and its derivatives have adhesive properties and are widely used in mucoadhesive drug delivery systems. Therefore, we wrapped flexible liposomes with trimethylated chitosan via electrostatic adsorption. The charge of the flexible liposomes became positive after encapsulation in TMC, and they remained stable in artificial tears. We assessed the safety of TMC-Lipo in cellular and zebrafish experiments a...
Source: International Journal of Biological Macromolecules - August 27, 2023 Category: Biochemistry Authors: Huan Gu Ping Chen Xing Liu Yan Lian Jingjing Xi Jingjing Li Jingyao Song Xiaofang Li Source Type: research
