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Potential protective effects of the water-soluble Chinese propolis on experimental ulcerative colitis
CONCLUSION: WSP downregulates OS by enhancing the function of endogenous antioxidant enzymes like SOD and GSH-Px, that inhibit neutrophil activity, as well as diminish pro-inflammatory cytokines like TNF-ɑ, IL-6, and IL-9, along with mechanisms that attenuate intestinal inflammation in UC rat model.PMID:37679980 | PMC:PMC10465833 | DOI:10.19852/j.cnki.jtcm.20230727.002
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Zhou Hua L I Hui Wang Haihua Source Type: research

A base-mediated synthesis of < em > N < /em > -hydroxy- and < em > N < /em > -alkoxyindoles from 2-nitrostyrenes
Tetrahedron. 2023 Sep 7;144:133578. doi: 10.1016/j.tet.2023.133578. Epub 2023 Aug 6.ABSTRACTSequential treatment of alkyl 2-(2-nitroaryl)-2-butenoates with potassium tert-butoxide and an electrophile, such as methyl iodide, benzyl bromide and allyl bromide, afforded N-alkoxyindoles. In related reactions, using sodium tert-pentoxide as the base with or without in situ addition of an electrophile afforded N-alkoxy- and N-hydroxyindoles, respectively. Electrophiles such as dimethylsulfate, p-tosyl chloride, and acetic anhydride afforded moderate yields of the respective N-methoxy-, N-tosyloxy, and N-acetoxyindoles, while meth...
Source: Tetrahedron - September 8, 2023 Category: Chemistry Authors: Blaine T McClay Katharine E Lambson Serge R Banini Tural N Akhmedov Bj örn C G Söderberg Source Type: research

Potential protective effects of the water-soluble Chinese propolis on experimental ulcerative colitis
CONCLUSION: WSP downregulates OS by enhancing the function of endogenous antioxidant enzymes like SOD and GSH-Px, that inhibit neutrophil activity, as well as diminish pro-inflammatory cytokines like TNF-ɑ, IL-6, and IL-9, along with mechanisms that attenuate intestinal inflammation in UC rat model.PMID:37679980 | PMC:PMC10465833 | DOI:10.19852/j.cnki.jtcm.20230727.002
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Zhou Hua L I Hui Wang Haihua Source Type: research

A base-mediated synthesis of < em > N < /em > -hydroxy- and < em > N < /em > -alkoxyindoles from 2-nitrostyrenes
Tetrahedron. 2023 Sep 7;144:133578. doi: 10.1016/j.tet.2023.133578. Epub 2023 Aug 6.ABSTRACTSequential treatment of alkyl 2-(2-nitroaryl)-2-butenoates with potassium tert-butoxide and an electrophile, such as methyl iodide, benzyl bromide and allyl bromide, afforded N-alkoxyindoles. In related reactions, using sodium tert-pentoxide as the base with or without in situ addition of an electrophile afforded N-alkoxy- and N-hydroxyindoles, respectively. Electrophiles such as dimethylsulfate, p-tosyl chloride, and acetic anhydride afforded moderate yields of the respective N-methoxy-, N-tosyloxy, and N-acetoxyindoles, while meth...
Source: Tetrahedron - September 8, 2023 Category: Chemistry Authors: Blaine T McClay Katharine E Lambson Serge R Banini Tural N Akhmedov Bj örn C G Söderberg Source Type: research

Potential protective effects of the water-soluble Chinese propolis on experimental ulcerative colitis
CONCLUSION: WSP downregulates OS by enhancing the function of endogenous antioxidant enzymes like SOD and GSH-Px, that inhibit neutrophil activity, as well as diminish pro-inflammatory cytokines like TNF-ɑ, IL-6, and IL-9, along with mechanisms that attenuate intestinal inflammation in UC rat model.PMID:37679980 | PMC:PMC10465833 | DOI:10.19852/j.cnki.jtcm.20230727.002
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Zhou Hua L I Hui Wang Haihua Source Type: research

Extraction, characterization and controlled release application of pectin-like/chitosan hydrogels system loaded Ciprofloxacin
CONCLUSION: The novel pectin-chitosan hydrogels hold the potential to enhance the quality of life for numerous patients by minimizing the need for frequent intake of chronic medications.PMID:37680160 | DOI:10.2174/1567201821666230901153513
Source: Current Drug Delivery - September 8, 2023 Category: Drugs & Pharmacology Authors: Amer Rashid Hameed Zeineb Mzoughi Mariem Itaimi Dammak Fawzi Habeeb Jabrail Didier Le Cerf Hatem Majdoub Source Type: research

A base-mediated synthesis of < em > N < /em > -hydroxy- and < em > N < /em > -alkoxyindoles from 2-nitrostyrenes
Tetrahedron. 2023 Sep 7;144:133578. doi: 10.1016/j.tet.2023.133578. Epub 2023 Aug 6.ABSTRACTSequential treatment of alkyl 2-(2-nitroaryl)-2-butenoates with potassium tert-butoxide and an electrophile, such as methyl iodide, benzyl bromide and allyl bromide, afforded N-alkoxyindoles. In related reactions, using sodium tert-pentoxide as the base with or without in situ addition of an electrophile afforded N-alkoxy- and N-hydroxyindoles, respectively. Electrophiles such as dimethylsulfate, p-tosyl chloride, and acetic anhydride afforded moderate yields of the respective N-methoxy-, N-tosyloxy, and N-acetoxyindoles, while meth...
Source: Tetrahedron - September 8, 2023 Category: Chemistry Authors: Blaine T McClay Katharine E Lambson Serge R Banini Tural N Akhmedov Bj örn C G Söderberg Source Type: research

Potential protective effects of the water-soluble Chinese propolis on experimental ulcerative colitis
CONCLUSION: WSP downregulates OS by enhancing the function of endogenous antioxidant enzymes like SOD and GSH-Px, that inhibit neutrophil activity, as well as diminish pro-inflammatory cytokines like TNF-ɑ, IL-6, and IL-9, along with mechanisms that attenuate intestinal inflammation in UC rat model.PMID:37679980 | PMC:PMC10465833 | DOI:10.19852/j.cnki.jtcm.20230727.002
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Zhou Hua L I Hui Wang Haihua Source Type: research

Extraction, characterization and controlled release application of pectin-like/chitosan hydrogels system loaded Ciprofloxacin
CONCLUSION: The novel pectin-chitosan hydrogels hold the potential to enhance the quality of life for numerous patients by minimizing the need for frequent intake of chronic medications.PMID:37680160 | DOI:10.2174/1567201821666230901153513
Source: Current Drug Delivery - September 8, 2023 Category: Drugs & Pharmacology Authors: Amer Rashid Hameed Zeineb Mzoughi Mariem Itaimi Dammak Fawzi Habeeb Jabrail Didier Le Cerf Hatem Majdoub Source Type: research

A base-mediated synthesis of < em > N < /em > -hydroxy- and < em > N < /em > -alkoxyindoles from 2-nitrostyrenes
Tetrahedron. 2023 Sep 7;144:133578. doi: 10.1016/j.tet.2023.133578. Epub 2023 Aug 6.ABSTRACTSequential treatment of alkyl 2-(2-nitroaryl)-2-butenoates with potassium tert-butoxide and an electrophile, such as methyl iodide, benzyl bromide and allyl bromide, afforded N-alkoxyindoles. In related reactions, using sodium tert-pentoxide as the base with or without in situ addition of an electrophile afforded N-alkoxy- and N-hydroxyindoles, respectively. Electrophiles such as dimethylsulfate, p-tosyl chloride, and acetic anhydride afforded moderate yields of the respective N-methoxy-, N-tosyloxy, and N-acetoxyindoles, while meth...
Source: Tetrahedron - September 8, 2023 Category: Chemistry Authors: Blaine T McClay Katharine E Lambson Serge R Banini Tural N Akhmedov Bj örn C G Söderberg Source Type: research

Extraction, characterization and controlled release application of pectin-like/chitosan hydrogels system loaded Ciprofloxacin
CONCLUSION: The novel pectin-chitosan hydrogels hold the potential to enhance the quality of life for numerous patients by minimizing the need for frequent intake of chronic medications.PMID:37680160 | DOI:10.2174/1567201821666230901153513
Source: Current Drug Delivery - September 8, 2023 Category: Drugs & Pharmacology Authors: Amer Rashid Hameed Zeineb Mzoughi Mariem Itaimi Dammak Fawzi Habeeb Jabrail Didier Le Cerf Hatem Majdoub Source Type: research

Potential protective effects of the water-soluble Chinese propolis on experimental ulcerative colitis
CONCLUSION: WSP downregulates OS by enhancing the function of endogenous antioxidant enzymes like SOD and GSH-Px, that inhibit neutrophil activity, as well as diminish pro-inflammatory cytokines like TNF-ɑ, IL-6, and IL-9, along with mechanisms that attenuate intestinal inflammation in UC rat model.PMID:37679980 | PMC:PMC10465833 | DOI:10.19852/j.cnki.jtcm.20230727.002
Source: Journal of Traditional Chinese Medicine - September 8, 2023 Category: Complementary Medicine Authors: Zhou Hua L I Hui Wang Haihua Source Type: research

Extraction, characterization and controlled release application of pectin-like/chitosan hydrogels system loaded Ciprofloxacin
CONCLUSION: The novel pectin-chitosan hydrogels hold the potential to enhance the quality of life for numerous patients by minimizing the need for frequent intake of chronic medications.PMID:37680160 | DOI:10.2174/1567201821666230901153513
Source: Current Drug Delivery - September 8, 2023 Category: Drugs & Pharmacology Authors: Amer Rashid Hameed Zeineb Mzoughi Mariem Itaimi Dammak Fawzi Habeeb Jabrail Didier Le Cerf Hatem Majdoub Source Type: research

A base-mediated synthesis of < em > N < /em > -hydroxy- and < em > N < /em > -alkoxyindoles from 2-nitrostyrenes
Tetrahedron. 2023 Sep 7;144:133578. doi: 10.1016/j.tet.2023.133578. Epub 2023 Aug 6.ABSTRACTSequential treatment of alkyl 2-(2-nitroaryl)-2-butenoates with potassium tert-butoxide and an electrophile, such as methyl iodide, benzyl bromide and allyl bromide, afforded N-alkoxyindoles. In related reactions, using sodium tert-pentoxide as the base with or without in situ addition of an electrophile afforded N-alkoxy- and N-hydroxyindoles, respectively. Electrophiles such as dimethylsulfate, p-tosyl chloride, and acetic anhydride afforded moderate yields of the respective N-methoxy-, N-tosyloxy, and N-acetoxyindoles, while meth...
Source: Tetrahedron - September 8, 2023 Category: Chemistry Authors: Blaine T McClay Katharine E Lambson Serge R Banini Tural N Akhmedov Bj örn C G Söderberg Source Type: research