Unveiling Key Pathological Indicators for Disease Progression in Vogt Koyanagi Harada Disease and Sympathetic Ophthalmia Through Advanced Choroidal Volume Analysis
CONCLUSIONS: The volume analysis of OCT images facilitates a three-dimensional visualization of choroidal alterations, which may serve as a reflection of disease severity in VKHD and SO patients. Furthermore, noninvasive initial CVV or CV measurements may serve as potential biomarkers for predicting disease recurrence in VKHD and SO.PMID:38709183 | DOI:10.1080/09273948.2024.2337836 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 6, 2024 Category: Allergy & Immunology Authors: Akira Tanikawa Kazuichi Maruyama Shiyi Liu Zaixing Mao Zhenguo Wang Nobuhiko Shiraki Noriyasu Hashida Ryo Kawasaki Kinpui Chan Kohji Nishida Source Type: research

Predisposing Factors and Clinical-Microbiological Profile of Neonatal Corneal Ulcer: A Systematic Review and Analysis
CONCLUSION: Based on the findings of reported studies, this systematic review has increased awareness of the risk factors and etiologies that lead to developing corneal ulcers in neonates.PMID:38709200 | DOI:10.1080/09273948.2024.2346246 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 6, 2024 Category: Allergy & Immunology Authors: Alireza Peyman Behrouz Rahimi Mahsa Pourmahdi-Boroujeni Majid Mirmohammadkhani Asieh Aslani Mohammad Soleimani Mahdi Abounoori Mohsen Pourazizi Source Type: research

A Rare Presentation: Bilateral Necrotizing Scleritis in Primary Sj ögren's Syndrome
CONCLUSION: This case underscores the unique presentation of pSS, characterized by bilateral necrotizing scleritis. The favorable outcome was attained through prompt immunosuppressive intervention and a collaborative, multidisciplinary approach. Further, this case report addresses a gap in the existing literature concerning pSS-related scleritis. It also emphasizes the crucial role of a rheumatologist in the comprehensive management of this condition.PMID:38709210 | DOI:10.1080/09273948.2024.2347573 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 6, 2024 Category: Allergy & Immunology Authors: Shishir Narain Richa Pyare P D Rath Source Type: research

Janus Kinase Inhibitors as a Third-Line Therapy for Refractory Endogenous Noninfectious Uveitis
CONCLUSIONS: In the absence of evidence from controlled clinical trials, JAK inhibitor therapy is still rendered experimental and currently considered only for sight-threatening uveitis. JAK inhibitors may be considered for specific NIU entities for which there is insufficient response or secondary loss of response to conventional or biologic disease-modifying drugs.PMID:38709218 | DOI:10.1080/09273948.2024.2348125 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 6, 2024 Category: Allergy & Immunology Authors: Justus G Garweg Kim A Straessle Source Type: research

Differential Composition and Structure of the Microbiota from Active and Inactive Stages of HLA-B27-associated Uveitis by Paired Fecal Metagenomes
CONCLUSION: The metagenomic profile of the fecal microbiota differs in the acute phase of the AAU compared to when the inflammation subsides, despite being the same individual and a short time-lapse. AAU is a fertile field for studying the connection between subtle rapid changes in microbiota and their systemic consequences.PMID:38709227 | DOI:10.1080/09273948.2024.2346818 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 6, 2024 Category: Allergy & Immunology Authors: Jos é Antonio Unzueta-Medina Susana Aide é González-Chávez Joan Sebastian Salas-Leiva Sandra Estela Silva-S ánchez C ésar Pacheco-Tena Source Type: research

Clinical and Transcriptional Profiles Reveal the Treatment Effect of Adalimumab in Patients with Initial-Onset and Recurrent Vogt-Koyanagi-Harada Disease
CONCLUSIONS: In patients with initial-onset VKH, adalimumab effectively reduces glucocorticoid dependence. However, adalimumab may not be effective for preventing relapse or providing long-term inflammation relief in patients with recurrent VKH.PMID:38709230 | DOI:10.1080/09273948.2024.2346814 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 6, 2024 Category: Allergy & Immunology Authors: Kailei Guo Xuanrong Xu Fuhua Yang Kaixuan Wang Xiaomin Zhang Source Type: research

Perinuclear Antineutrophil Cytoplasmic Antibody-Associated Ocular Manifestations: Case Series and Literature Review
CONCLUSION: Anterior segment ocular manifestations are not uncommon and can be the initial presentation of p-ANCA-associated vasculitis (AAV). Therefore, its evaluation should be considered in establishing the diagnosis of AAV, a life-threatening disease.PMID:38709232 | DOI:10.1080/09273948.2024.2346820 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 6, 2024 Category: Allergy & Immunology Authors: Yi Wen Lim On Heong Liew Source Type: research

Widespread Adoption of Microincision Vitrectomy Surgery Improves Visual Outcomes in Endogenous Endophthalmitis with Poor Initial Vision: A 21-Year Experience in Taiwan
CONCLUSION: In endogenous endophthalmitis patients presenting with poor initial visual acuity, vitrectomy was a better visual prognostic factor. MIVS has allowed more patients to undergo vitrectomy and improved visual outcomes.PMID:38691837 | DOI:10.1080/09273948.2024.2338272 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 1, 2024 Category: Allergy & Immunology Authors: Shih-Chou Chen Tsung-Tien Wu Chun-Hao Yin Jin-Shuen Chen Yao-Shen Chen Source Type: research

Adalimumab for the Treatment of Non-Infectious Uveitis: A Real Life Experience
CONCLUSIONS: We consider adalimumab as a leading drug in the treatment of NIU with high safety and efficacy.PMID:38691840 | DOI:10.1080/09273948.2024.2344712 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 1, 2024 Category: Allergy & Immunology Authors: F átima Raad Paula Luque Sof ía García Ledo Alicia Alda Lozano V íctor Llorens Antonio Espejo Henar Heras Luc ía Santana Luis Trapiella Patricia Fanlo Alfredo Ad án Gerard Espinosa Nuria Navarrete Source Type: research

Evaluation of Choroidal Thickness and Choroidal Vascularity Index in Patients with Rheumatoid Arthritis
CONCLUSION: We demonstrated thinning in CT and decreased CVI for the first time in RA patients by comparing it with the control group.PMID:38691844 | DOI:10.1080/09273948.2024.2345289 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 1, 2024 Category: Allergy & Immunology Authors: G ülce Gökgöz Özışık Dilek Eker Buyuksireci Tayfun Şahin Ayla Cagl ıyan Turk Source Type: research

Widespread Adoption of Microincision Vitrectomy Surgery Improves Visual Outcomes in Endogenous Endophthalmitis with Poor Initial Vision: A 21-Year Experience in Taiwan
CONCLUSION: In endogenous endophthalmitis patients presenting with poor initial visual acuity, vitrectomy was a better visual prognostic factor. MIVS has allowed more patients to undergo vitrectomy and improved visual outcomes.PMID:38691837 | DOI:10.1080/09273948.2024.2338272 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 1, 2024 Category: Allergy & Immunology Authors: Shih-Chou Chen Tsung-Tien Wu Chun-Hao Yin Jin-Shuen Chen Yao-Shen Chen Source Type: research

Adalimumab for the Treatment of Non-Infectious Uveitis: A Real Life Experience
CONCLUSIONS: We consider adalimumab as a leading drug in the treatment of NIU with high safety and efficacy.PMID:38691840 | DOI:10.1080/09273948.2024.2344712 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 1, 2024 Category: Allergy & Immunology Authors: F átima Raad Paula Luque Sof ía García Ledo Alicia Alda Lozano V íctor Llorens Antonio Espejo Henar Heras Luc ía Santana Luis Trapiella Patricia Fanlo Alfredo Ad án Gerard Espinosa Nuria Navarrete Source Type: research

Evaluation of Choroidal Thickness and Choroidal Vascularity Index in Patients with Rheumatoid Arthritis
CONCLUSION: We demonstrated thinning in CT and decreased CVI for the first time in RA patients by comparing it with the control group.PMID:38691844 | DOI:10.1080/09273948.2024.2345289 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 1, 2024 Category: Allergy & Immunology Authors: G ülce Gökgöz Özışık Dilek Eker Buyuksireci Tayfun Şahin Ayla Cagl ıyan Turk Source Type: research

Widespread Adoption of Microincision Vitrectomy Surgery Improves Visual Outcomes in Endogenous Endophthalmitis with Poor Initial Vision: A 21-Year Experience in Taiwan
CONCLUSION: In endogenous endophthalmitis patients presenting with poor initial visual acuity, vitrectomy was a better visual prognostic factor. MIVS has allowed more patients to undergo vitrectomy and improved visual outcomes.PMID:38691837 | DOI:10.1080/09273948.2024.2338272 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 1, 2024 Category: Allergy & Immunology Authors: Shih-Chou Chen Tsung-Tien Wu Chun-Hao Yin Jin-Shuen Chen Yao-Shen Chen Source Type: research

Adalimumab for the Treatment of Non-Infectious Uveitis: A Real Life Experience
CONCLUSIONS: We consider adalimumab as a leading drug in the treatment of NIU with high safety and efficacy.PMID:38691840 | DOI:10.1080/09273948.2024.2344712 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 1, 2024 Category: Allergy & Immunology Authors: F átima Raad Paula Luque Sof ía García Ledo Alicia Alda Lozano V íctor Llorens Antonio Espejo Henar Heras Luc ía Santana Luis Trapiella Patricia Fanlo Alfredo Ad án Gerard Espinosa Nuria Navarrete Source Type: research