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Expanding Research Capacity in Sub-Saharan Africa Through Informatics, Bioinformatics, and Data Science Training Programs in Mali
Conclusion Bioinformatics and data science training programs in developing countries necessitate incremental and collaborative strategies for their feasible and sustainable development. The progress described here covered decades of collaborative efforts centered on training and research on computationally intensive topics. These efforts laid the groundwork and platforms conducive for hosting a bioinformatics and data science training program in Mali. Training programs are perhaps best facilitated through Africa’s university systems as they are perhaps best positioned to maintain core resources during lapses in sho...
Source: Frontiers in Genetics - April 11, 2019 Category: Genetics & Stem Cells Source Type: research

Current vector control challenges in the fight against malaria in Brazil
Abstract In Brazil, malaria is an important public health problem first reported in 1560. Historically, fluctuations in malaria cases in Brazil are attributed to waves of economic development; construction of railroads, highways, and hydroelectric dams; and population displacement and land occupation policies. Vector control measures have been widely used with an important role in reducing malaria cases. In this review article, we reviewed the vector control measures established in the Brazilian territory and aspects associated with such measures for malaria. Although some vector control measures are routinely used in Braz...
Source: Revista da Sociedade Brasileira de Medicina Tropical - March 8, 2019 Category: Tropical Medicine Source Type: research

Cochrane Infectious Disease Group works with WHO on latest guidelines for malaria vector control
The World Health Organization publishedGuidelines for malaria vector control, drawing on seven Cochrane reviews specially prepared for them by theCochrane Infectious Diseases Group (CIDG).  With its editorial base at Liverpool School of Tropical Medicine (LSTM), CIDG was asked to review all of the evidence that was used in bringing together what WHO have described as a “one-stop shop” for countries and partners working to implement effective malaria vector control measures. Consolidating more than 20 sets of WHO recommendations and good practice statements into one user friendly document, the guidelines support each c...
Source: Cochrane News and Events - March 5, 2019 Category: Information Technology Authors: Muriah Umoquit Source Type: news

Experimental Study on Plasmodium berghei, Anopheles Stephensi, and BALB/c Mouse System: Implications for Malaria Transmission Blocking Assays.
Conclusion: This study helps to understand the biology of vertebrate-parasite and mosquito-malaria interactions that may aid in the development of a new generation of drug/vaccine and vector-based measures for malaria control. PMID: 30697308 [PubMed]
Source: Iranian Journal of Parasitology - February 1, 2019 Category: Parasitology Tags: Iran J Parasitol Source Type: research

Featured Review: Piperonyl butoxide (PBO) combined with pyrethroids in insecticide ‐treated nets to prevent malaria in Africa
Review confirms that using pyrethroid-PBO treated nets to prevent malaria is more effective at killing mosquitoes in areas where there is a high level of resistance to pyrethroids.The distribution of nets treated with pyrethroid insecticides has been very effective in reducing malaria transmission during the past two decades in Africa. However, there has been a rise in the number of mosquitoes developing resistance to pyrethroids, which is the only class of insecticides currently used to treat nets.In a new Cochrane review, an independent team of review authors led byKatherine Gleave andNatalie Lissenden at the Liverpool S...
Source: Cochrane News and Events - November 29, 2018 Category: Information Technology Authors: Muriah Umoquit Source Type: news

Impact, economic evaluation, and sustainability of integrated vector management in urban settings to prevent vector-borne diseases: a scoping review
ConclusionsIVM has an impact on reducing vector breeding sites and the entomology index, but evidence of impacts on health outcomes is limited. Social outcomes are improved abilities and capacities, empowerment, and community knowledge. Economic evaluations are scarce, and cost-effectiveness is dependent on illness incidence. Community capacity building is the main component of sustainability, together with collaboration, institutionalization, and routinization of activities. Findings indicate a great heterogeneity in the interventions and highlight the need for characterizing interventions rigorously to facilitate transferability.
Source: Infectious Diseases of Poverty - September 3, 2018 Category: Infectious Diseases Source Type: research

The Role of Molecular Techniques on Malaria Control and Elimination Programs in Iran: A Review Article.
Conclusion: The application of molecular methods may be of particular interest for malaria control/elimination programs, for monitoring progress towards malaria elimination, and for optimal orientation of program activities. PMID: 30069199 [PubMed]
Source: Iranian Journal of Parasitology - August 4, 2018 Category: Parasitology Tags: Iran J Parasitol Source Type: research

Effects of the removal or reduction in density of the malaria mosquito, Anopheles gambiae s.l., on interacting predators and competitors in local ecosystems
Medical and Veterinary Entomology, EarlyView.
Source: Medical and Veterinary Entomology - July 25, 2018 Category: Veterinary Research Authors: C. M. Collins , J. A. S. Bonds , M. M. Quinlan , J. D. Mumford Source Type: research

A Revival of Epidemiological Entomology in Senegal.
Abstract The term epidemiological entomology was first coined by Garrett-Jones over half a century ago1 but has been out of fashion for far too long.2 In this issue, Sougoufara et al.3 illustrate clearly just how insightful such an approach can be when applied to characterizing key properties of a dynamic malaria transmission system before and after the scale-up of vector control with long-lasting insecticidal nets in Dielmo, Senegal. Using simple analytical models first pioneered by Garrett-Jones himself,4 these authors illustrate how not all may be as it appears based on direct interpretation of entomological da...
Source: The American Journal of Tropical Medicine and Hygiene - March 26, 2018 Category: Tropical Medicine Authors: Killeen GF Tags: Am J Trop Med Hyg Source Type: research

Studies on the resting behaviour and host choice of Anopheles gambiae and An.  arabiensis from Muleba, Tanzania
Abstract The relative efficacy of a mechanical (Prokopack) collection method vs. manual aspiration in the collection of resting mosquitoes was evaluated in northern Tanzania before and after an intervention using indoor residual spraying and longlasting insecticide‐treated nets. In smoke‐free houses mosquitoes were collected from the roof and walls, but in smoky houses mosquitoes were found predominantly on the walls. Anopheles gambiae (Diptera: Culicidae) constituted 97.7% of the 312 An. gambiae complex specimens identified before but only 19.3% of the 183 identified after the intervention. A single sampling with the...
Source: Medical and Veterinary Entomology - February 26, 2018 Category: Veterinary Research Authors: J. D. Charlwood, E. Kessy, K. Yohannes, N. Protopopoff, M. Rowland, C. LeClair Tags: Original Article Source Type: research

A novel nested polymerase chain reaction assay targeting Plasmodium mitochondrial DNA in field ‐collected Anopheles mosquitoes
Abstract Sensitive techniques for the detection of Plasmodium (Aconoidasida: Plasmodiidae) sporozoites in field‐collected malaria vectors are essential for the correct assessment of risk for malaria transmission. A real‐time polymerase chain reaction (RT‐PCR) protocol targeting Plasmodium mtDNA proved to be much more sensitive in detecting sporozoites in mosquitoes than the widely used enzyme‐linked immunosorbent assay targeting Plasmodium circumsporozoite protein (CSP‐ELISA). However, because of the relatively high costs associated with equipment and reagents, RT‐PCRs are mostly used to assess the outcomes of ...
Source: Medical and Veterinary Entomology - January 18, 2018 Category: Veterinary Research Authors: M. Calzetta, E. Perugini, G. Seixas, C. A. Sousa, W. M. Guelbeogo, N. Sagnon, A. Della Torre, J. Pinto, M. Pombi, E. Mancini Tags: Short Communication Source Type: research

malERA: An updated research agenda for basic science and enabling technologies in malaria elimination and eradication
by The malERA Refresh Consultative Panel on Basic Science and Enabling Technologies Basic science holds enormous power for revealing the biological mechanisms of disease and, in turn, paving the way toward new, effective interventions. Recognizing this power, the 2011 Research Agenda for Malaria Eradication included key priorities in fundamental research that, if attained, could help accelerate progress toward disease elimination and eradication. The Malaria Eradication Research Agenda (malERA) Consultative Panel on Basic Science and Enabling Technologies reviewed the progress, continuing challenges, and major opportuniti...
Source: PLoS Medicine - November 30, 2017 Category: Internal Medicine Authors: The malERA Refresh Consultative Panel on Basic Science and Enabling Technologies Source Type: research

Falciparum Malaria Outbreak in Sabah Linked to an Immigrant Rubber Tapper.
In conclusion, an outbreak of P. falciparum malaria was introduced into a malaria-free village by a migrant rubber tapper, by whom the imported parasite was introduced to the community via vector Anopheles balabacensis. Living near stagnant water bodies was the risk factor in this outbreak. PMID: 29141714 [PubMed - as supplied by publisher]
Source: The American Journal of Tropical Medicine and Hygiene - November 6, 2017 Category: Tropical Medicine Authors: Jeffree SM, Ahmed K, Safian N, Hassan R, Mihat O, Lukman KA, Shamsudin SB, Kamaludin F Tags: Am J Trop Med Hyg Source Type: research

Gold nanoparticles - against parasites and insect vectors.
Abstract Nanomaterials are currently considered for many biological, biomedical and environmental purposes, due to their outstanding physical and chemical properties. The synthesis of gold nanoparticles (Au NPs) is of high interest for research in parasitology and entomology, since these nanomaterials showed promising applications, ranging from detection techniques to drug development, against a rather wide range of parasites of public health relevance, as well as on insect vectors. Here, I review current knowledge about the bioactivity of Au NPs on selected insect species of public health relevance, including maj...
Source: Acta Tropica - October 29, 2017 Category: Infectious Diseases Authors: Benelli G Tags: Acta Trop Source Type: research

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