Cognitive maps and the magnetic sense in vertebrates
Curr Opin Neurobiol. 2024 Apr 23;86:102880. doi: 10.1016/j.conb.2024.102880. Online ahead of print.ABSTRACTNavigation requires a network of neurons processing inputs from internally generated cues and external landmarks. Most studies on the neuronal basis of navigation in vertebrates have focused on rats and mice and the canonical senses vision, hearing, olfaction, and somatosensation. Some animals have evolved the ability to sense the Earth's magnetic field and use it for orientation. It can be expected that in these animals magnetic cues are integrated with other sensory cues in the cognitive map. We provide an overview ...
Source: Current Opinion in Neurobiology - April 24, 2024 Category: Neurology Authors: Runita N Shirdhankar E Pascal Malkemper Source Type: research
Dynamic skin behaviors in cephalopods
Curr Opin Neurobiol. 2024 Apr 22;86:102876. doi: 10.1016/j.conb.2024.102876. Online ahead of print.ABSTRACTThe coleoid cephalopods (cuttlefish, octopus, and squid) are a group of soft-bodied mollusks that exhibit a wealth of complex behaviors, including dynamic camouflage, object mimicry, skin-based visual communication, and dynamic body patterns during sleep. Many of these behaviors are visually driven and engage the animals' color changing skin, a pixelated display that is directly controlled by neurons projecting from the brain. Thus, cephalopod skin provides a direct readout of neural activity in the brain. During camo...
Source: Current Opinion in Neurobiology - April 23, 2024 Category: Neurology Authors: Erica N Shook George Thomas Barlow Daniella Garcia-Rosales Connor J Gibbons Tessa G Montague Source Type: research
Dynamic skin behaviors in cephalopods
Curr Opin Neurobiol. 2024 Apr 22;86:102876. doi: 10.1016/j.conb.2024.102876. Online ahead of print.ABSTRACTThe coleoid cephalopods (cuttlefish, octopus, and squid) are a group of soft-bodied mollusks that exhibit a wealth of complex behaviors, including dynamic camouflage, object mimicry, skin-based visual communication, and dynamic body patterns during sleep. Many of these behaviors are visually driven and engage the animals' color changing skin, a pixelated display that is directly controlled by neurons projecting from the brain. Thus, cephalopod skin provides a direct readout of neural activity in the brain. During camo...
Source: Current Opinion in Neurobiology - April 23, 2024 Category: Neurology Authors: Erica N Shook George Thomas Barlow Daniella Garcia-Rosales Connor J Gibbons Tessa G Montague Source Type: research
Microglia phagocytic mechanisms: Development informing disease
Curr Opin Neurobiol. 2024 Apr 16;86:102877. doi: 10.1016/j.conb.2024.102877. Online ahead of print.ABSTRACTMicroglia are tissue-resident macrophages and professional phagocytes of the central nervous system (CNS). In development, microglia-mediated phagocytosis is important for sculpting the cellular architecture. This includes the engulfment of dead/dying cells, pruning extranumerary synapses and axons, and phagocytosing fragments of myelin sheaths. Intriguingly, these developmental phagocytic mechanisms by which microglia sculpt the CNS are now appreciated as important for eliminating synapses, myelin, and proteins durin...
Source: Current Opinion in Neurobiology - April 17, 2024 Category: Neurology Authors: Rebecca M Beiter Patrick W Sheehan Dorothy P Schafer Source Type: research
Microglia phagocytic mechanisms: Development informing disease
Curr Opin Neurobiol. 2024 Apr 16;86:102877. doi: 10.1016/j.conb.2024.102877. Online ahead of print.ABSTRACTMicroglia are tissue-resident macrophages and professional phagocytes of the central nervous system (CNS). In development, microglia-mediated phagocytosis is important for sculpting the cellular architecture. This includes the engulfment of dead/dying cells, pruning extranumerary synapses and axons, and phagocytosing fragments of myelin sheaths. Intriguingly, these developmental phagocytic mechanisms by which microglia sculpt the CNS are now appreciated as important for eliminating synapses, myelin, and proteins durin...
Source: Current Opinion in Neurobiology - April 17, 2024 Category: Neurology Authors: Rebecca M Beiter Patrick W Sheehan Dorothy P Schafer Source Type: research
Editorial overview: Introduction to neurobiology of disease
Curr Opin Neurobiol. 2024 Apr 11;86:102875. doi: 10.1016/j.conb.2024.102875. Online ahead of print.NO ABSTRACTPMID:38608479 | DOI:10.1016/j.conb.2024.102875 (Source: Current Opinion in Neurobiology)
Source: Current Opinion in Neurobiology - April 12, 2024 Category: Neurology Authors: Erik S Musiek Eric J Nestler Source Type: research
Editorial overview: Introduction to neurobiology of disease
Curr Opin Neurobiol. 2024 Apr 11;86:102875. doi: 10.1016/j.conb.2024.102875. Online ahead of print.NO ABSTRACTPMID:38608479 | DOI:10.1016/j.conb.2024.102875 (Source: Current Opinion in Neurobiology)
Source: Current Opinion in Neurobiology - April 12, 2024 Category: Neurology Authors: Erik S Musiek Eric J Nestler Source Type: research
Editorial overview: Introduction to neurobiology of disease
Curr Opin Neurobiol. 2024 Apr 11;86:102875. doi: 10.1016/j.conb.2024.102875. Online ahead of print.NO ABSTRACTPMID:38608479 | DOI:10.1016/j.conb.2024.102875 (Source: Current Opinion in Neurobiology)
Source: Current Opinion in Neurobiology - April 12, 2024 Category: Neurology Authors: Erik S Musiek Eric J Nestler Source Type: research
Toward a neuroscience of natural behavior
Curr Opin Neurobiol. 2024 Apr 6;86:102859. doi: 10.1016/j.conb.2024.102859. Online ahead of print.ABSTRACTOne of the most exciting new developments in systems neuroscience is the progress being made toward neurophysiological experiments that move beyond simplified laboratory settings and address the richness of natural behavior. This is enabled by technological advances such as wireless recording in freely moving animals, automated quantification of behavior, and new methods for analyzing large data sets. Beyond new empirical methods and data, however, there is also a need for new theories and concepts to interpret that da...
Source: Current Opinion in Neurobiology - April 7, 2024 Category: Neurology Authors: Paul Cisek Andrea M Green Source Type: research
Toward a neuroscience of natural behavior
Curr Opin Neurobiol. 2024 Apr 6;86:102859. doi: 10.1016/j.conb.2024.102859. Online ahead of print.ABSTRACTOne of the most exciting new developments in systems neuroscience is the progress being made toward neurophysiological experiments that move beyond simplified laboratory settings and address the richness of natural behavior. This is enabled by technological advances such as wireless recording in freely moving animals, automated quantification of behavior, and new methods for analyzing large data sets. Beyond new empirical methods and data, however, there is also a need for new theories and concepts to interpret that da...
Source: Current Opinion in Neurobiology - April 7, 2024 Category: Neurology Authors: Paul Cisek Andrea M Green Source Type: research
Toward a neuroscience of natural behavior
Curr Opin Neurobiol. 2024 Apr 6;86:102859. doi: 10.1016/j.conb.2024.102859. Online ahead of print.ABSTRACTOne of the most exciting new developments in systems neuroscience is the progress being made toward neurophysiological experiments that move beyond simplified laboratory settings and address the richness of natural behavior. This is enabled by technological advances such as wireless recording in freely moving animals, automated quantification of behavior, and new methods for analyzing large data sets. Beyond new empirical methods and data, however, there is also a need for new theories and concepts to interpret that da...
Source: Current Opinion in Neurobiology - April 7, 2024 Category: Neurology Authors: Paul Cisek Andrea M Green Source Type: research
Toward a neuroscience of natural behavior
Curr Opin Neurobiol. 2024 Apr 6;86:102859. doi: 10.1016/j.conb.2024.102859. Online ahead of print.ABSTRACTOne of the most exciting new developments in systems neuroscience is the progress being made toward neurophysiological experiments that move beyond simplified laboratory settings and address the richness of natural behavior. This is enabled by technological advances such as wireless recording in freely moving animals, automated quantification of behavior, and new methods for analyzing large data sets. Beyond new empirical methods and data, however, there is also a need for new theories and concepts to interpret that da...
Source: Current Opinion in Neurobiology - April 7, 2024 Category: Neurology Authors: Paul Cisek Andrea M Green Source Type: research
Toward a neuroscience of natural behavior
Curr Opin Neurobiol. 2024 Apr 6;86:102859. doi: 10.1016/j.conb.2024.102859. Online ahead of print.ABSTRACTOne of the most exciting new developments in systems neuroscience is the progress being made toward neurophysiological experiments that move beyond simplified laboratory settings and address the richness of natural behavior. This is enabled by technological advances such as wireless recording in freely moving animals, automated quantification of behavior, and new methods for analyzing large data sets. Beyond new empirical methods and data, however, there is also a need for new theories and concepts to interpret that da...
Source: Current Opinion in Neurobiology - April 7, 2024 Category: Neurology Authors: Paul Cisek Andrea M Green Source Type: research
A metabolic perspective to sleep genetics
Curr Opin Neurobiol. 2024 Apr 5;86:102874. doi: 10.1016/j.conb.2024.102874. Online ahead of print.ABSTRACTThe metabolic signals that regulate sleep and the metabolic functions that occur during sleep are active areas of research. Prior studies have focused on sugars and nucleotides but new genetic evidence suggests novel functions of lipid and amino acid metabolites in sleep. Additional genetic studies of energetic signaling pathways and the circadian clock transcription factor network have increased our understanding of how sleep responds to changes in the metabolic state. This review focuses on key recent insights from g...
Source: Current Opinion in Neurobiology - April 6, 2024 Category: Neurology Authors: Daniel C Levine Louis J Pt áček Ying-Hui Fu Source Type: research
From innate to instructed: A new look at perceptual decision-making
Curr Opin Neurobiol. 2024 Apr 2;86:102871. doi: 10.1016/j.conb.2024.102871. Online ahead of print.ABSTRACTUnderstanding how subjects perceive sensory stimuli in their environment and use this information to guide appropriate actions is a major challenge in neuroscience. To study perceptual decision-making in animals, researchers use tasks that either probe spontaneous responses to stimuli (often described as "naturalistic") or train animals to associate stimuli with experimenter-defined responses. Spontaneous decisions rely on animals' pre-existing knowledge, while trained tasks offer greater versatility, albeit often at t...
Source: Current Opinion in Neurobiology - April 3, 2024 Category: Neurology Authors: Lukas T Oesch Michael B Ryan Anne K Churchland Source Type: research
