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Drug: Dexamethasone

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Total 6494 results found since Jan 2013.

Overactivated Epithelial NF- κB Disrupts Lung Development in Congenital Diaphragmatic Hernia
Am J Respir Cell Mol Biol. 2023 Aug 8. doi: 10.1165/rcmb.2023-0138OC. Online ahead of print.ABSTRACTAbnormal lung development is the main cause of morbidity and mortality in neonates with congenital diaphragmatic hernia (CDH), a common birth defect (1:2500) of largely unknown pathobiology. Recent studies discovered that inflammatory processes, and specifically NF-κB associated pathways are enriched in human and experimental CDH. However, the molecular signaling of NF-κB in abnormal CDH lung development and its potential as a therapeutic target requires further investigation. Using sections and hypoplastic lung explant cu...
Source: Am J Respir Cell Mol... - August 8, 2023 Category: Respiratory Medicine Authors: Florentine Dylong Jan Riedel Gaurang M Amonkar Nicole Peukert Paula Lieckfeldt Katinka Sturm Benedikt H öxter Wai Hei Tse Yuichiro Miyake Maria Moormann Lena Marie Bode Steffi Mayer Richard Keijzer Martin Lacher Xingbin Ai Jan-Hendrik Gosemann Richard Wa Source Type: research

Therapy for Chikungunya Arthritis: A Study of 133 Brazilian Patients
Am J Trop Med Hyg. 2023 Aug 7:tpmd230205. doi: 10.4269/ajtmh.23-0205. Online ahead of print.ABSTRACTChikungunya fever is a global vector-borne viral disease. Patients with acute chikungunya are usually treated symptomatically. The arthritic phase may be self-limiting. However, many patients develop extremely disabling arthritis that does not improve after months. The aim of this study was to describe the treatment of chikungunya arthritis (CHIKA) patients. A medical records review was conducted in 133 CHIKA patients seen at a rheumatology practice. Patients were diagnosed by clinical criteria and confirmed by the presence ...
Source: The American Journal of Tropical Medicine and Hygiene - August 7, 2023 Category: Tropical Medicine Authors: Jos é Kennedy Amaral Clifton O Bingham Peter C Taylor Luis M Vil á Michael E Weinblatt Robert T Schoen Source Type: research

Statistical modeling and optimization of dexamethasone adsorption from aqueous solution by Fe3O4@NH2-MIL88B nanorods: Isotherm, Kinetics, and Thermodynamic
Environ Res. 2023 Aug 3:116773. doi: 10.1016/j.envres.2023.116773. Online ahead of print.ABSTRACTThe presence of pharmaceutical compounds in the environment poses a significant threat to human and aquatic animal health. Dexamethasone (DEX), a synthetic steroid hormone with endocrine-disrupting effects, is one such compound that needs to be effectively removed before discharging into the environment. This research presents a novel approach utilizing magnetically recyclable Fe3O4@NH2-MIL88B NRs as an efficient adsorbent for the treatment of DEX from aqueous solutions. The synthesized adsorbent was characterized by X-ray diff...
Source: Environmental Research - August 5, 2023 Category: Environmental Health Authors: Mohammad Hassan Mahmoudian Ali Azari Anis Jahantigh Maryam Sarkhosh Mahmood Yousefi Seyed Ali Razavinasab Maryam Afsharizadeh Fatemeh Mohammadi Shahraji Abbas Pour Pasandi Ali Zeidabadi Tayebeh Ilaghinezhad Bardsiri Mohammad Ghasemian Source Type: research

Venous Thromboembolism Risk in Patients With Newly Diagnosed Multiple Myeloma Treated with Carfilzomib or Bortezomib in Combination With Lenalidomide and Dexamethasone
CONCLUSION: In this cohort, KRd was not associated with an increase in VTE risk compared to VRd, contrary to prior literature.PMID:37543510 | DOI:10.1016/j.clml.2023.07.009
Source: Clinical Lymphoma and Myeloma - August 5, 2023 Category: Cancer & Oncology Authors: Alexa J Loncharich Mark A Fiala Michael J Slade Angela Vickroy Margaret Kavanaugh Carmen Wilson Mark A Schroeder Keith Stockerl-Goldstein Ravi Vij Kristen M Sanfilippo Source Type: research