Perioperative management of mastocytosis
ConclusionIntraoperative anaphylaxis can be the first presenting sign of mastocytosis. Patients with mastocytosis who received chronic antimediator therapy and/or preoperative prophylactic medications had an uneventful surgical course. (Source: Journal of Anesthesia)
Source: Journal of Anesthesia - October 1, 2023 Category: Anesthesiology Source Type: research
Supportive care and antiviral treatments in primary herpetic gingivostomatitis: a systematic review
CONCLUSIONS: Although PHGS is a disease with a high worldwide prevalence, the lack of consensus about therapeutic management indicates gaps in existing evidence. Most of the proposed treatment consists in symptomatic drugs with empiric regimens which are ineffective for the viral replication. The main limit to realize randomized clinical trial is due to the rapid onset and remission of the disease. In fact, the diagnostic delay, estimated in 72 h, decreases the effectiveness of any antiviral drugs.CLINICAL RELEVANCE: Out of the five studies included in this systematic review, only one was able to provide some weak evidence...
Source: Herpes - September 21, 2023 Category: Infectious Diseases Authors: Noemi Coppola Tiziana Cantile Daniela Adamo Federica Canfora Stefania Baldares Francesco Riccitiello Gennaro Musella Michele Davide D Mignogna Stefania Leuci Source Type: research
Supportive care and antiviral treatments in primary herpetic gingivostomatitis: a systematic review
CONCLUSIONS: Although PHGS is a disease with a high worldwide prevalence, the lack of consensus about therapeutic management indicates gaps in existing evidence. Most of the proposed treatment consists in symptomatic drugs with empiric regimens which are ineffective for the viral replication. The main limit to realize randomized clinical trial is due to the rapid onset and remission of the disease. In fact, the diagnostic delay, estimated in 72 h, decreases the effectiveness of any antiviral drugs.CLINICAL RELEVANCE: Out of the five studies included in this systematic review, only one was able to provide some weak evidence...
Source: Herpes - September 21, 2023 Category: Infectious Diseases Authors: Noemi Coppola Tiziana Cantile Daniela Adamo Federica Canfora Stefania Baldares Francesco Riccitiello Gennaro Musella Michele Davide D Mignogna Stefania Leuci Source Type: research
Supportive care and antiviral treatments in primary herpetic gingivostomatitis: a systematic review
ConclusionsAlthough PHGS is a disease with a high worldwide prevalence, the lack of consensus about therapeutic management indicates gaps in existing evidence. Most of the proposed treatment consists in symptomatic drugs with empiric regimens which are ineffective for the viral replication. The main limit to realize randomized clinical trial is due to the rapid onset and remission of the disease. In fact, the diagnostic delay, estimated in 72 h, decreases the effectiveness of any antiviral drugs.Clinical relevanceOut of the five studies included in this systematic review, only one was able to provide some weak evidence t...
Source: Clinical Oral Investigations - September 21, 2023 Category: Dentistry Source Type: research
A case of diphenhydramine intoxication showing prolonged false positive tricyclic antidepressant in the urine assay
CONCLUSION: The present case suggests that diphenhydramine overdose may cause cerebellar ataxia and show prolonged cross-reactivity as TCA in the urine.PMID:37706054 | PMC:PMC10423011 | DOI:10.2478/abm-2023-0042 (Source: Biomed Res)
Source: Biomed Res - September 14, 2023 Category: Research Authors: Dongsun Kim Hyun Young Shin Bon D Ku Source Type: research
A case of diphenhydramine intoxication showing prolonged false positive tricyclic antidepressant in the urine assay
CONCLUSION: The present case suggests that diphenhydramine overdose may cause cerebellar ataxia and show prolonged cross-reactivity as TCA in the urine.PMID:37706054 | PMC:PMC10423011 | DOI:10.2478/abm-2023-0042 (Source: Biomed Res)
Source: Biomed Res - September 14, 2023 Category: Research Authors: Dongsun Kim Hyun Young Shin Bon D Ku Source Type: research
Percutaneous absorption and Skin accumulation of Lorazepam-Diphenhydramine- Haloperidol Carbopol gel in Porcine Ear Skin
In conclusion, the ABH Carbopol gel provides a promising alternative to the ABH PLO gel for treating CINV in hospice patients. Further studies are required to validate these findings in clinical settings.PMID:37700110 | DOI:10.1208/s12249-023-02608-6 (Source: AAPS PharmSciTech)
Source: AAPS PharmSciTech - September 12, 2023 Category: Drugs & Pharmacology Authors: Rabin Neupane Sai H S Boddu Moawia M Al-Tabakha Shery Jacob R Jayachandra Babu Amit K Tiwari Source Type: research
Percutaneous absorption and Skin accumulation of Lorazepam-Diphenhydramine- Haloperidol Carbopol gel in Porcine Ear Skin
In conclusion, the ABH Carbopol gel provides a promising alternative to the ABH PLO gel for treating CINV in hospice patients. Further studies are required to validate these findings in clinical settings.PMID:37700110 | DOI:10.1208/s12249-023-02608-6 (Source: AAPS PharmSciTech)
Source: AAPS PharmSciTech - September 12, 2023 Category: Drugs & Pharmacology Authors: Rabin Neupane Sai H S Boddu Moawia M Al-Tabakha Shery Jacob R Jayachandra Babu Amit K Tiwari Source Type: research
Percutaneous absorption and Skin accumulation of Lorazepam-Diphenhydramine- Haloperidol Carbopol gel in Porcine Ear Skin
In conclusion, the ABH Carbopol gel provides a promising alternative to the ABH PLO gel for treating CINV in hospice patients. Further studies are required to validate these findings in clinical settings.PMID:37700110 | DOI:10.1208/s12249-023-02608-6 (Source: AAPS PharmSciTech)
Source: AAPS PharmSciTech - September 12, 2023 Category: Drugs & Pharmacology Authors: Rabin Neupane Sai H S Boddu Moawia M Al-Tabakha Shery Jacob R Jayachandra Babu Amit K Tiwari Source Type: research
Percutaneous absorption and Skin accumulation of Lorazepam-Diphenhydramine- Haloperidol Carbopol gel in Porcine Ear Skin
In conclusion, the ABH Carbopol gel provides a promising alternative to the ABH PLO gel for treating CINV in hospice patients. Further studies are required to validate these findings in clinical settings.PMID:37700110 | DOI:10.1208/s12249-023-02608-6 (Source: AAPS PharmSciTech)
Source: AAPS PharmSciTech - September 12, 2023 Category: Drugs & Pharmacology Authors: Rabin Neupane Sai H S Boddu Moawia M Al-Tabakha Shery Jacob R Jayachandra Babu Amit K Tiwari Source Type: research
A novel chitosan-based doxepin nano-formulation for chemotherapy-induced oral mucositis: a randomized, double-blinded, placebo-controlled clinical trial
CONCLUSION: Chitosan-based doxepin nano-formulation might be a promising alternative for routine treatments of oral mucositis.PMID:37668810 | DOI:10.1007/s10787-023-01325-7 (Source: Cancer Control)
Source: Cancer Control - September 5, 2023 Category: Cancer & Oncology Authors: Nazafarin Samiraninezhad Mostafa Rezaee Ahmad Gholami Ali Amanati Maryam Mardani Source Type: research
Analysis of Risk Factors for Infusion-Related Reactions Following Rituximab Administration in Patients with Desensitization before Renal Transplantation
In conclusion, the male sex, high actual body weight, BSA, and BMI may be new predictive markers for rituximab-induced IRRs in renal transplant recipients. Therefore, clinicians should carefully monitor patients who receive rituximab before renal transplantation and present with the predictive markers.PMID:37661411 | DOI:10.1248/bpb.b23-00157 (Source: Biological and Pharmaceutical Bulletin)
Source: Biological and Pharmaceutical Bulletin - September 4, 2023 Category: Drugs & Pharmacology Authors: Hironobu Nishiura Masaya Takahashi Tomoaki Iwai Junji Uchida Yasutaka Nakamura Source Type: research
Dose adjustment of rheumatology and allergy/immunology medications in chronic kidney disease: awareness and knowledge among internal medicine housestaff
CONCLUSION: Overall, awareness and knowledge were poor among IMHS for dose adjustments of rheumatology and allergy/immunology medications in patients with CKD. Proper education and exposure to nephrology during training may improve quality and safety of care for patients with CKD.PMID:37663380 | PMC:PMC10472844 | DOI:10.1080/08998280.2023.2228172 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - September 4, 2023 Category: Universities & Medical Training Authors: Jessica M Loiodice Joshua Fogel Sofia Rubinstein Source Type: research
Analysis of Risk Factors for Infusion-Related Reactions Following Rituximab Administration in Patients with Desensitization before Renal Transplantation
In conclusion, the male sex, high actual body weight, BSA, and BMI may be new predictive markers for rituximab-induced IRRs in renal transplant recipients. Therefore, clinicians should carefully monitor patients who receive rituximab before renal transplantation and present with the predictive markers.PMID:37661411 | DOI:10.1248/bpb.b23-00157 (Source: Biological and Pharmaceutical Bulletin)
Source: Biological and Pharmaceutical Bulletin - September 4, 2023 Category: Drugs & Pharmacology Authors: Hironobu Nishiura Masaya Takahashi Tomoaki Iwai Junji Uchida Yasutaka Nakamura Source Type: research
Dose adjustment of rheumatology and allergy/immunology medications in chronic kidney disease: awareness and knowledge among internal medicine housestaff
CONCLUSION: Overall, awareness and knowledge were poor among IMHS for dose adjustments of rheumatology and allergy/immunology medications in patients with CKD. Proper education and exposure to nephrology during training may improve quality and safety of care for patients with CKD.PMID:37663380 | PMC:PMC10472844 | DOI:10.1080/08998280.2023.2228172 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - September 4, 2023 Category: Universities & Medical Training Authors: Jessica M Loiodice Joshua Fogel Sofia Rubinstein Source Type: research
