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Vaccination: Cervical Cancer Vaccine
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Total 2139 results found since Jan 2013.
Knowledge, perceptions and uptake of human papilloma virus vaccine among adolescent girls in Kampala, Uganda; a mixed-methods school-based study
CONCLUSION: Girls generally had low levels of knowledge, negative perceptions, and poor uptake of HPV vaccination. We recommend sensitization campaigns in schools and communities to improve awareness, perceptions, and practices of stakeholders towards HPV vaccination.PMID:37461002 | DOI:10.1186/s12887-023-04174-z
Source: Cancer Control - July 17, 2023 Category: Cancer & Oncology Authors: Glet Kakuru Bitariho Doreen Tuhebwe Arnold Tigaiza Aisha Nalugya Tonny Ssekamatte Suzanne N Kiwanuka Source Type: research
Dual anti-PD-(L)1/TGF- β inhibitors in cancer immunotherapy - Updated
Int Immunopharmacol. 2023 Jul 15;122:110648. doi: 10.1016/j.intimp.2023.110648. Online ahead of print.ABSTRACTImmune checkpoint inhibitor (ICI) therapy suffers from tumor resistance and relapse in majority of patients due to the suppressive tumor immune microenvironment (TIME). Advances in the field have brought about development of fusion proteins able to target two signaling simultaneously and to exert maximal anti-cancer immunity. Bispecific inhibitors of transforming growth factor (TGF)-β signaling and programmed death-1 (PD-1) or programmed death-ligand 1 (PD-L1) are developed to reduce the rate of relapse and to ach...
Source: International Immunopharmacology - July 17, 2023 Category: Allergy & Immunology Authors: Zana Karami Keywan Mortezaee Jamal Majidpoor Source Type: research
Opportunities to accelerate immunization progress in middle-income countries
Vaccine. 2023 Jul 15:S0264-410X(23)00782-X. doi: 10.1016/j.vaccine.2023.06.079. Online ahead of print.ABSTRACTThere has been increasing recognition of vaccine access challenges in middle-income countries and the need for increased action, particularly in countries that are not eligible for or have transitioned out of Gavi, the Vaccine Alliance support. These countries' immunization systems are more vulnerable than ever as the COVID-19 pandemic exacerbates existing programme challenges, increasing the risk of delayed vaccine introductions, backsliding immunization coverage rates, and increased coverage inequity. The potenti...
Source: Vaccine - July 17, 2023 Category: Allergy & Immunology Authors: Jason Zhu Clarke B Cole Johanna Fihman Alex Adjagba Mira Dasic Tania Cernuschi Source Type: research
Managing the transition in cervical screening methods for Taiwan: Policy recommendations and perspectives
J Formos Med Assoc. 2023 Jul 12:S0929-6646(23)00246-2. doi: 10.1016/j.jfma.2023.06.018. Online ahead of print.ABSTRACTSince government-provided annual cervical cytology testing for all Taiwanese women aged 30 years or older became available in 1995, both cervical cancer incidence and death have decreased significantly. However, with the 2018 introduction of the national immunization program for human papillomavirus (HPV) vaccination in all schoolgirls aged 13-15 years old, the positive predictive value of cytology testing is expected to decrease with rising vaccination rates, and therefore a transition to more sensitive HP...
Source: J Formos Med Assoc - July 14, 2023 Category: General Medicine Authors: Chien-Chin Chen Chyong-Huey Lai Chih-Long Chang Wen-Fang Cheng Raoh-Fang Pwu Jane Tsai Peng-Hui Wang Jacqueline Whang-Peng Gi-Ming Lai Source Type: research
Small Molecule Inhibitors of Human Papillomavirus: A Review of Research from 1997 to 2021
Curr Med Chem. 2023 Jul 13. doi: 10.2174/0929867331666230713165407. Online ahead of print.ABSTRACTHuman papillomavirus (HPV) infections are the cause of warts, lesions and cancer, with different types of HPV causing different symptoms. HPV infections are the primary cause of cervical cancer. There are over 220 different types of HPV, and only nine of these can currently be vaccinated. There is a need to treat these viral infections without just treating the symptoms of the infection, as is currently the main method. There is a wide range of small molecules that have been used to inhibit various stages of the HPV infectious...
Source: Current Medicinal Chemistry - July 14, 2023 Category: Chemistry Authors: Caitlin L Duncan Hendra Gunosewoyo Mauro Mocerino Alan D Payne Source Type: research
Managing the transition in cervical screening methods for Taiwan: Policy recommendations and perspectives
J Formos Med Assoc. 2023 Jul 12:S0929-6646(23)00246-2. doi: 10.1016/j.jfma.2023.06.018. Online ahead of print.ABSTRACTSince government-provided annual cervical cytology testing for all Taiwanese women aged 30 years or older became available in 1995, both cervical cancer incidence and death have decreased significantly. However, with the 2018 introduction of the national immunization program for human papillomavirus (HPV) vaccination in all schoolgirls aged 13-15 years old, the positive predictive value of cytology testing is expected to decrease with rising vaccination rates, and therefore a transition to more sensitive HP...
Source: J Formos Med Assoc - July 14, 2023 Category: General Medicine Authors: Chien-Chin Chen Chyong-Huey Lai Chih-Long Chang Wen-Fang Cheng Raoh-Fang Pwu Jane Tsai Peng-Hui Wang Jacqueline Whang-Peng Gi-Ming Lai Source Type: research
Small Molecule Inhibitors of Human Papillomavirus: A Review of Research from 1997 to 2021
Curr Med Chem. 2023 Jul 13. doi: 10.2174/0929867331666230713165407. Online ahead of print.ABSTRACTHuman papillomavirus (HPV) infections are the cause of warts, lesions and cancer, with different types of HPV causing different symptoms. HPV infections are the primary cause of cervical cancer. There are over 220 different types of HPV, and only nine of these can currently be vaccinated. There is a need to treat these viral infections without just treating the symptoms of the infection, as is currently the main method. There is a wide range of small molecules that have been used to inhibit various stages of the HPV infectious...
Source: Current Medicinal Chemistry - July 14, 2023 Category: Chemistry Authors: Caitlin L Duncan Hendra Gunosewoyo Mauro Mocerino Alan D Payne Source Type: research
Clinical Characteristics of Human Papillomavirus Infection in the Male Genital Tract
CONCLUSIONS: The rates of male HPV infection are high, particularly among individuals aged 17-40. Low-risk infections (types 6 and 11) cause male reproductive tract symptoms, including abnormal growth. High-risk infection (HPV52) correlates with local women's HPV subtype distribution and potential transmission. Therefore, screening for male HPV infection is crucial in preventing cervical cancer. Authorities should promote the development and early use of male HPV vaccines.PMID:37442188
Source: Alternative Therapies in Health and Medicine - July 13, 2023 Category: Complementary Medicine Authors: Tiantian Gou Ping Liu Xiuju Yao Lin Zhang Source Type: research
The antiviral effects of a MEK1/2 inhibitor promote tumor regression in a preclinical model of human papillomavirus infection-induced tumorigenesis
Antiviral Res. 2023 Jul 8:105667. doi: 10.1016/j.antiviral.2023.105667. Online ahead of print.ABSTRACTHuman papillomaviruses (HPVs) are a significant public health concern due to their widespread transmission, morbidity, and oncogenic potential. Despite efficacious vaccines, millions of unvaccinated individuals and those with existing infections will develop HPV-related diseases for the next two decades and beyond. The continuing burden of HPV-related diseases is exacerbated by the lack of effective therapies or cures for infections, highlighting the need to identify and develop antivirals. The experimental murine papillom...
Source: Antiviral Research - July 10, 2023 Category: Virology Authors: Adrian J Luna Jesse M Young Rosa T Sterk Virginie Bondu Fred A Schultz Donna F Kusewitt Huining Kang Michelle A Ozbun Source Type: research
Awareness, perceptions, and acceptance of human papillomavirus vaccination among parents in Hong Kong
CONCLUSION: Parents in Hong Kong are hesitant about HPV vaccination for their sons. This barrier could be removed by providing information to correct vaccine safety misconceptions and offering a gender-neutral vaccination programme through the school-based Childhood Immunisation Programme.PMID:37409372 | DOI:10.12809/hkmj2210470
Source: Hong Kong Med J - July 6, 2023 Category: General Medicine Authors: E W H Lam H Y S Ngan K Y Kun D F H Li W Y Wan P K S Chan Source Type: research
