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Therapy: Radiation Therapy
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Total 11602 results found since Jan 2013.
Radiation Therapy Changed the Second Malignancy Pattern in Rectal Cancer Survivors
Conclusions: RT may change the second malignancy pattern in rectal cancer survivors; the risk of prostate cancer decreased, and the risk of thyroid cancer increased most significantly.PMID:37629753 | PMC:PMC10456705 | DOI:10.3390/medicina59081463
Source: Medicina (Kaunas) - August 26, 2023 Category: Universities & Medical Training Authors: Xiaoxian Ye Yinuo Tan Ruishuang Ma Pengrong Lou Ying Yuan Source Type: research
Gynecological Fistulae-Has Anything Changed in the Diagnosis and Treatment over the Last Decade? A Narrative Literature Review
Medicina (Kaunas). 2023 Aug 12;59(8):1455. doi: 10.3390/medicina59081455.ABSTRACTGynecological fistulae are a rare but severe complication of radiation therapy, pelvic surgery, prolonged labor, cesarean deliveries, or inflammatory bowel diseases. A gynecological fistula is an abnormal pathway formed between the urinary and gynecological tract, most commonly located between the urinary bladder and vagina. Vesico-uterine and vesicovaginal fistulae are an important health issue, common in women of reproductive age in developing countries with limited access to obstetrical care. Various surgical techniques have been described ...
Source: Medicina (Kaunas) - August 26, 2023 Category: Universities & Medical Training Authors: Marek Misiak Michalina Dworak Ma łgorzata Wyszomirska Maria Kurt Maciej Wal ędziak Anna R óżańska-Walędziak Source Type: research
ΔNp63 Regulates Radioresistance in Human Head and Neck Squamous Carcinoma Cells
Curr Issues Mol Biol. 2023 Jul 27;45(8):6262-6271. doi: 10.3390/cimb45080394.ABSTRACTRadiation therapy is commonly used to treat head and neck squamous cell carcinoma (HNSCC); however, recurrence results from the development of radioresistant cancer cells. Therefore, it is necessary to identify the underlying mechanisms of radioresistance in HNSCC. Previously, we showed that the inhibition of karyopherin-β1 (KPNB1), a factor in the nuclear transport system, enhances radiation-induced cytotoxicity, specifically in HNSCC cells, and decreases the localization of SCC-specific transcription factor ΔNp63. This suggests that Δ...
Source: Current Issues in Molecular Biology - August 25, 2023 Category: Molecular Biology Authors: Kota Sato Hironori Yoshino Yoshiaki Sato Manabu Nakano Eichi Tsuruga Source Type: research
Survivorship Navigation for Young Women With Early-Stage Breast Cancer
DISCUSSION: Survivorship visit navigation is feasible for young breast cancer patients. These visits can influence knowledge gained and intended future health plans and behaviors. Systematic approaches to survivorship care may improve the physical and mental health of cancer survivors. Future health care delivery research focused on survivorship is warranted.PMID:37625925 | DOI:10.1016/j.clbc.2023.07.009
Source: Clinical Genitourinary Cancer - August 25, 2023 Category: Cancer & Oncology Authors: Lauren P Knelson Shoshana Rosenberg Craig Snow Kathryn Rigby Johanna Lynch Tal Sella Alicia Morgans Ann H Partridge Source Type: research
Patient specific quality assurance in SBRT: a systematic review of measurement-based methods
Phys Med Biol. 2023 Aug 25. doi: 10.1088/1361-6560/acf43a. Online ahead of print.ABSTRACTThis topical review focuses on Patient-Specific Quality Assurance (PSQA) approaches to stereotactic body radiation therapy (SBRT). SBRT requires stricter accuracy than standard radiation therapy due to the high dose per fraction and the limited number of fractions. The review considered various PSQA methods reported in 36 articles between 01/2010-07/2022 for SBRT treatment. In particular comparison among devices and devices designed for SBRT, sensitivity and resolution, verification methodology, gamma analysis were specifically conside...
Source: Physics in Medicine and Biology - August 25, 2023 Category: Physics Authors: Tiziana Malatesta Alessandro Scaggion Francesca Romana Giglioli Gina Belmonte Michelina Casale Paolo Colleoni Maria Daniela Falco Alessia Giuliano Stefania Linsalata Carmelo Marino Eugenia Moretti Veronica Richetto Anna Sardo Serenella Russo Pietro Mancos Source Type: research
Tumour status prediction by means of carbon-ion beam irradiation: comparison of washout rates between in-beam PET and DCE-MRI in rats
Phys Med Biol. 2023 Aug 25. doi: 10.1088/1361-6560/acf438. Online ahead of print.ABSTRACTOBJECTIVE: Tumour response to radiation therapy appears as changes in tumour vascular condition. There are several methods for analysing tumour blood circulatory changes one of which is dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), but there is no method that can observe the tumour vascular condition and physiological changes at the site of radiation therapy. Positron emission tomography (PET) has been applied for treatment verification in charged particle therapy, which is based on the detection of positron emitters ...
Source: Physics in Medicine and Biology - August 25, 2023 Category: Physics Authors: Chie Toramatsu Akram Mohammadi Hidekatsu Wakizaka Nobuhiro Nitta Yoko Ikoma Chie Seki Iwao Kanno Taiga Yamaya Source Type: research
Locoregional Treatment for Early-Stage Breast Cancer: Current Status and Future Perspectives
Curr Oncol. 2023 Aug 10;30(8):7520-7531. doi: 10.3390/curroncol30080545.ABSTRACTBACKGROUND: The locoregional recurrence of breast cancer has been reduced due to the multidisciplinary approach of breast surgery, systemic therapy and radiation. Early detection and better surgical techniques contribute to an improvement in breast cancer outcomes.PURPOSE OF REVIEW: The purpose of this review is to have an overview and summary of the current evidence behind the current approaches to the locoregional treatment of breast cancer and to discuss its future direction.SUMMARY: With improved surgical techniques and the use of a more ef...
Source: Cancer Control - August 25, 2023 Category: Cancer & Oncology Authors: Sayeh Lavasani Erin Healy Kari Kansal Source Type: research
Survivorship Navigation for Young Women With Early-Stage Breast Cancer
DISCUSSION: Survivorship visit navigation is feasible for young breast cancer patients. These visits can influence knowledge gained and intended future health plans and behaviors. Systematic approaches to survivorship care may improve the physical and mental health of cancer survivors. Future health care delivery research focused on survivorship is warranted.PMID:37625925 | DOI:10.1016/j.clbc.2023.07.009
Source: Clinical Breast Cancer - August 25, 2023 Category: Cancer & Oncology Authors: Lauren P Knelson Shoshana Rosenberg Craig Snow Kathryn Rigby Johanna Lynch Tal Sella Alicia Morgans Ann H Partridge Source Type: research
Patient specific quality assurance in SBRT: a systematic review of measurement-based methods
Phys Med Biol. 2023 Aug 25. doi: 10.1088/1361-6560/acf43a. Online ahead of print.ABSTRACTThis topical review focuses on Patient-Specific Quality Assurance (PSQA) approaches to stereotactic body radiation therapy (SBRT). SBRT requires stricter accuracy than standard radiation therapy due to the high dose per fraction and the limited number of fractions. The review considered various PSQA methods reported in 36 articles between 01/2010-07/2022 for SBRT treatment. In particular comparison among devices and devices designed for SBRT, sensitivity and resolution, verification methodology, gamma analysis were specifically conside...
Source: Physics in Medicine and Biology - August 25, 2023 Category: Physics Authors: Tiziana Malatesta Alessandro Scaggion Francesca Romana Giglioli Gina Belmonte Michelina Casale Paolo Colleoni Maria Daniela Falco Alessia Giuliano Stefania Linsalata Carmelo Marino Eugenia Moretti Veronica Richetto Anna Sardo Serenella Russo Pietro Mancos Source Type: research
Tumour status prediction by means of carbon-ion beam irradiation: comparison of washout rates between in-beam PET and DCE-MRI in rats
Phys Med Biol. 2023 Aug 25. doi: 10.1088/1361-6560/acf438. Online ahead of print.ABSTRACTOBJECTIVE: Tumour response to radiation therapy appears as changes in tumour vascular condition. There are several methods for analysing tumour blood circulatory changes one of which is dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), but there is no method that can observe the tumour vascular condition and physiological changes at the site of radiation therapy. Positron emission tomography (PET) has been applied for treatment verification in charged particle therapy, which is based on the detection of positron emitters ...
Source: Physics in Medicine and Biology - August 25, 2023 Category: Physics Authors: Chie Toramatsu Akram Mohammadi Hidekatsu Wakizaka Nobuhiro Nitta Yoko Ikoma Chie Seki Iwao Kanno Taiga Yamaya Source Type: research
Blocking the functional domain of TIP1 by antibodies sensitizes cancer to radiation therapy
Biomed Pharmacother. 2023 Aug 23;166:115341. doi: 10.1016/j.biopha.2023.115341. Online ahead of print.ABSTRACTNon-small-cell lung cancer (NSCLC) and glioblastoma (GB) have poor prognoses. Discovery of new molecular targets is needed to improve therapy. Tax interacting protein 1 (TIP1), which plays a role in cancer progression, is overexpressed and radiation-inducible in NSCLC and GB. We evaluated the effect of an anti-TIP1 antibody alone and in combination with ionizing radiation (XRT) on NSCLC and GB in vitro and in vivo. NSCLC and GB cells were treated with anti-TIP1 antibodies and evaluated for proliferation, colony for...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - August 25, 2023 Category: Drugs & Pharmacology Authors: Abhay K Singh David Ya Dadey Michael J Rau James Fitzpatrick Harendra K Shah Minakshi Saikia Reid Townsend Dinesh Thotala Dennis E Hallahan Vaishali Kapoor Source Type: research
X-ray radiation-induced intestinal barrier dysfunction in human epithelial Caco-2 cell monolayers
In this study, we investigated radiation-induced alterations in TJ-related proteins in an intestinal epithelial cell model. Caco-2 cells were irradiated with 2, 5, and 10 Gy and harvested 1 and 24 h after X-ray exposure. The trypan blue assay revealed that cell viability was reduced in a dose-dependent manner 24 h after X-ray exposure compared to that of non-irradiated cells. However, the WST-8 assay revealed that cell proliferation was significantly reduced only 24 h after radiation exposure to 10 Gy compared to that of non-irradiated cells. In addition, a decreased growth rate and increased doubling time were observed in...
Source: Ecotoxicology and Environmental Safety - August 25, 2023 Category: Environmental Health Authors: Ha-Young Park Jin-Hee Yu Source Type: research
ΔNp63 Regulates Radioresistance in Human Head and Neck Squamous Carcinoma Cells
Curr Issues Mol Biol. 2023 Jul 27;45(8):6262-6271. doi: 10.3390/cimb45080394.ABSTRACTRadiation therapy is commonly used to treat head and neck squamous cell carcinoma (HNSCC); however, recurrence results from the development of radioresistant cancer cells. Therefore, it is necessary to identify the underlying mechanisms of radioresistance in HNSCC. Previously, we showed that the inhibition of karyopherin-β1 (KPNB1), a factor in the nuclear transport system, enhances radiation-induced cytotoxicity, specifically in HNSCC cells, and decreases the localization of SCC-specific transcription factor ΔNp63. This suggests that Δ...
Source: Current Issues in Molecular Biology - August 25, 2023 Category: Molecular Biology Authors: Kota Sato Hironori Yoshino Yoshiaki Sato Manabu Nakano Eichi Tsuruga Source Type: research
