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Cancer: Squamous Cell Carcinoma
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Total 19037 results found since Jan 2013.
Identification of molecular biomarkers associated with non-small-cell lung carcinoma (NSCLC) using whole-exome sequencing
CONCLUSIONS: Our bioinformatics analysis identified KCNJ18, GPRIN2, TEKT4, HRNR, FOLR3, ESSRA, CTBP2, MPRIP, TBP, and FBXO6 may contribute to progression in NSCLC and could be used as new biomarkers for the treatment. The mechanism by which GPRIN2, KCNJ12, and TEKT4 contribute to tumorigenesis is unclear, but our results suggest they may play an important role in NSCLC and it is worth investigating in future.PMID:37694353 | DOI:10.3233/CBM-220211
Source: Cancer Biomarkers : Section A of Disease Markers - September 11, 2023 Category: Cancer & Oncology Authors: Varsha Singh Amit Katiyar Prabhat Malik Sunil Kumar Anant Mohan Harpreet Singh Deepali Jain Source Type: research
Bioinformatics analysis of CUL2/4A/9 and its function in head and neck squamous cell carcinoma
CONCLUSION: These results suggest that the transcriptional levels of CUL2/4A/9 were upregulated and these genes could affect proliferation and migration of HNSCC cells. Therefore, CUL2/4A/9 could potentially function as novel independent biomarkers in HNSCC patients.PMID:37695034 | DOI:10.5603/EP.a2023.0029
Source: Endokrynologia Polska - September 11, 2023 Category: Endocrinology Authors: Bingqing Xu Ruohuang Wang Jisheng Zhang Lin Wang Xin Cui Fangyu Chai Xiaoyun Du Yan Jiang Source Type: research
Identification of molecular biomarkers associated with non-small-cell lung carcinoma (NSCLC) using whole-exome sequencing
CONCLUSIONS: Our bioinformatics analysis identified KCNJ18, GPRIN2, TEKT4, HRNR, FOLR3, ESSRA, CTBP2, MPRIP, TBP, and FBXO6 may contribute to progression in NSCLC and could be used as new biomarkers for the treatment. The mechanism by which GPRIN2, KCNJ12, and TEKT4 contribute to tumorigenesis is unclear, but our results suggest they may play an important role in NSCLC and it is worth investigating in future.PMID:37694353 | DOI:10.3233/CBM-220211
Source: Cancer Biomarkers : Section A of Disease Markers - September 11, 2023 Category: Cancer & Oncology Authors: Varsha Singh Amit Katiyar Prabhat Malik Sunil Kumar Anant Mohan Harpreet Singh Deepali Jain Source Type: research
Bioinformatics analysis of CUL2/4A/9 and its function in head and neck squamous cell carcinoma
CONCLUSION: These results suggest that the transcriptional levels of CUL2/4A/9 were upregulated and these genes could affect proliferation and migration of HNSCC cells. Therefore, CUL2/4A/9 could potentially function as novel independent biomarkers in HNSCC patients.PMID:37695034 | DOI:10.5603/EP.a2023.0029
Source: Endokrynologia Polska - September 11, 2023 Category: Endocrinology Authors: Bingqing Xu Ruohuang Wang Jisheng Zhang Lin Wang Xin Cui Fangyu Chai Xiaoyun Du Yan Jiang Source Type: research
Systematic evaluation of TP53 codon 72 polymorphism associated with onset and progression of oral potentially malignant disorders
CONCLUSION: Our data of a pooled-analysis indicates that TP53 codon 72 polymorphism may not act as genetic factor for the risk of OPMD onset and progression. Combined with the conclusion by a systematic review and meta-analysis, we put forward a new opinion that TP53 genetic typing cloud not influence p53 protein expression in OPMD.PMID:37697274 | DOI:10.1186/s12903-023-03316-0
Source: Cancer Control - September 11, 2023 Category: Cancer & Oncology Authors: Huangkai Li Yu Liu Shanxin Zhou Qin Zhou Xi Yang Source Type: research
A pH-Activatable Nanoprobe Labels Diverse Histologic Subtypes of Human Lung Cancer During Resection
CONCLUSIONS: This translational study demonstrates the feasibility of pegsitacianine as an IMI probe to label the two most common histologic subtypes of human lung cancer.PMID:37697109 | DOI:10.1007/s11307-023-01853-2
Source: Mol Biol Cell - September 11, 2023 Category: Molecular Biology Authors: Gregory Thomas Kennedy Feredun S Azari Ashley Chang Austin Chang Patrick Bou-Samra Charuhas Desphande Edward J Delikatny Evgeniy Eruslanov John C Kucharczuk David C Rice Sunil Singhal Source Type: research
Ribosomal RNA gene downregulation in head and neck squamous carcinoma cells correlates with rDNA promoter hypermethylation
Gene. 2023 Sep 9:147793. doi: 10.1016/j.gene.2023.147793. Online ahead of print.ABSTRACTEukaryotes carry hundreds of ribosomal RNA (rRNA) genes as tandem arrays, which generate rRNA for protein synthesis. Humans carry ∼ 400 rRNA gene copies and their expression is epigenetically regulated. Dysregulation of rRNA synthesis and ribosome biogenesis are characteristic features of cancers. Targeting aberrant rRNA expression for cancer therapy is being explored. Head and neck squamous cell carcinoma (HNSCC) is among the most prevalent cancers globally. Using quantitative PCR and bisulfite sequencing, we show that rRNA genes are...
Source: Gene - September 11, 2023 Category: Genetics & Stem Cells Authors: Neha Priyadarshini Navinchandra Venkatarama Puppala Jayasree Peroth Jayaprakash Piyush Khandelia Vivek Sharma Gireesha Mohannath Source Type: research
Bioinformatics analysis of CUL2/4A/9 and its function in head and neck squamous cell carcinoma
CONCLUSION: These results suggest that the transcriptional levels of CUL2/4A/9 were upregulated and these genes could affect proliferation and migration of HNSCC cells. Therefore, CUL2/4A/9 could potentially function as novel independent biomarkers in HNSCC patients.PMID:37695034 | DOI:10.5603/EP.a2023.0029
Source: Endokrynologia Polska - September 11, 2023 Category: Endocrinology Authors: Bingqing Xu Ruohuang Wang Jisheng Zhang Lin Wang Xin Cui Fangyu Chai Xiaoyun Du Yan Jiang Source Type: research
Ribosomal RNA gene downregulation in head and neck squamous carcinoma cells correlates with rDNA promoter hypermethylation
Gene. 2023 Sep 9:147793. doi: 10.1016/j.gene.2023.147793. Online ahead of print.ABSTRACTEukaryotes carry hundreds of ribosomal RNA (rRNA) genes as tandem arrays, which generate rRNA for protein synthesis. Humans carry ∼ 400 rRNA gene copies and their expression is epigenetically regulated. Dysregulation of rRNA synthesis and ribosome biogenesis are characteristic features of cancers. Targeting aberrant rRNA expression for cancer therapy is being explored. Head and neck squamous cell carcinoma (HNSCC) is among the most prevalent cancers globally. Using quantitative PCR and bisulfite sequencing, we show that rRNA genes are...
Source: Gene - September 11, 2023 Category: Genetics & Stem Cells Authors: Neha Priyadarshini Navinchandra Venkatarama Puppala Jayasree Peroth Jayaprakash Piyush Khandelia Vivek Sharma Gireesha Mohannath Source Type: research
Bioinformatics analysis of CUL2/4A/9 and its function in head and neck squamous cell carcinoma
CONCLUSION: These results suggest that the transcriptional levels of CUL2/4A/9 were upregulated and these genes could affect proliferation and migration of HNSCC cells. Therefore, CUL2/4A/9 could potentially function as novel independent biomarkers in HNSCC patients.PMID:37695034 | DOI:10.5603/EP.a2023.0029
Source: Endokrynologia Polska - September 11, 2023 Category: Endocrinology Authors: Bingqing Xu Ruohuang Wang Jisheng Zhang Lin Wang Xin Cui Fangyu Chai Xiaoyun Du Yan Jiang Source Type: research
Identification of molecular biomarkers associated with non-small-cell lung carcinoma (NSCLC) using whole-exome sequencing
CONCLUSIONS: Our bioinformatics analysis identified KCNJ18, GPRIN2, TEKT4, HRNR, FOLR3, ESSRA, CTBP2, MPRIP, TBP, and FBXO6 may contribute to progression in NSCLC and could be used as new biomarkers for the treatment. The mechanism by which GPRIN2, KCNJ12, and TEKT4 contribute to tumorigenesis is unclear, but our results suggest they may play an important role in NSCLC and it is worth investigating in future.PMID:37694353 | DOI:10.3233/CBM-220211
Source: Cancer Biomarkers : Section A of Disease Markers - September 11, 2023 Category: Cancer & Oncology Authors: Varsha Singh Amit Katiyar Prabhat Malik Sunil Kumar Anant Mohan Harpreet Singh Deepali Jain Source Type: research
Machine-Learning-Aided Prediction of Brain Metastases Development in Non-Small-Cell Lung Cancers
CONCLUSION: Analysis of the importance of input features suggests that the models are learning the relevant relationships between clinical features/development of BM. A higher number of samples is to be prioritized to improve performance. Employed prospectively at initial diagnosis, such models can help select high-risk subgroups for surveillance brain MRI.PMID:37689579 | DOI:10.1016/j.cllc.2023.08.002
Source: Clinical Lung Cancer - September 9, 2023 Category: Cancer & Oncology Authors: Giovanni Vison à Lisa M Spiller Sophia Hahn Elke Hattingen Thomas J Vogl Gabriele Schweikert Katrin Bankov Melanie Demes Henning Reis Peter Wild Pia S Zeiner Fabian Acker Martin Sebastian Katharina J Wenger Source Type: research
