Filtered By:
Cancer: Skin Cancer
This page shows you your search results in order of date. This is page number 19.
Order by Relevance | Date
Total 36609 results found since Jan 2013.
Pten knockout affects drug resistance differently in melanoma and kidney cancer
CONCLUSIONS: The results confirmed heterogenous cell responses to PTEN loss, which may lead to a better understanding of the role of PTEN in particular types of tumors and points to PTEN as a therapeutic target for personalized medicine.PMID:37673853 | DOI:10.1007/s43440-023-00523-y
Source: Pharmacological Reports - September 6, 2023 Category: Drugs & Pharmacology Authors: Klaudia Brodaczewska Aleksandra Majewska Aleksandra Filipiak-Duliban Claudine Kieda Source Type: research
Prognostic value of lactate dehydrogenase in patients with uveal melanoma treated with immune checkpoint inhibition
CONCLUSIONS: In UM patients treated with ICIs, the LDH levels were reliable indicators of prognosis.PMID:37671944 | DOI:10.18632/aging.204996
Source: Aging - September 6, 2023 Category: Biomedical Science Authors: Xiaocui Liang Shan Zhou Zefeng Xiao Source Type: research
Significant risk of second primary cancer among laryngeal squamous cell carcinoma patients even after 20 years
Conclusion: Patients with LSCC as primary cancer have a 60% excess risk for an SPC, especially for tobacco-associated cancers, remaining significantly elevated even decades after treatment.PMID:37672344 | DOI:10.1080/0284186X.2023.2254482
Source: Acta Oncologica - September 6, 2023 Category: Cancer & Oncology Authors: Rayan Nikkil ä Elli Hirvonen Aaro Haapaniemi Laura Tapiovaara Janne Pitk äniemi Nea Malila Antti M äkitie Source Type: research
Socioeconomic position and the pre-diagnostic interval among patients diagnosed with head and neck squamous cell carcinoma - a population-based study from DAHANCA
CONCLUSION: The interval from symptom onset to diagnosis and consultation patterns were similar across SEP groups. Still, socioeconomic differences in stage at diagnosis were observed for some - but not all - subsites.PMID:37672036 | DOI:10.1080/0284186X.2023.2254478
Source: Acta Oncologica - September 6, 2023 Category: Cancer & Oncology Authors: Maja Halgren Olsen Thomas Maltesen Pernille Lassen Trille Kristina Kjaer J ørgen Johansen Hanne Primdahl Elo Andersen Claus Andrup Kristensen Maria Andersen Mohammad Farhadi Jens Overgaard Susanne Oksbjerg Dalton Source Type: research
Comprehensive analysis of P2Y family genes expression, immune characteristics, and prognosis in pan-cancer
CONCLUSION: P2Ys may be used as potential pan-cancer biomarkers in prognosis and immunology. They may also be new targets for tumor immunotherapy, which has wide clinical implications.PMID:37672858 | DOI:10.1016/j.tranon.2023.101776
Source: Translational Oncology - September 6, 2023 Category: Cancer & Oncology Authors: Chuan Liu Xiaoli Wang Siwei Wang Jiankang Xiang Huabing Xie Zongbiao Tan Xinshu Li Jixiang Zhang Weiguo Dong Source Type: research
Significant risk of second primary cancer among laryngeal squamous cell carcinoma patients even after 20 years
Conclusion: Patients with LSCC as primary cancer have a 60% excess risk for an SPC, especially for tobacco-associated cancers, remaining significantly elevated even decades after treatment.PMID:37672344 | DOI:10.1080/0284186X.2023.2254482
Source: Acta Oncologica - September 6, 2023 Category: Cancer & Oncology Authors: Rayan Nikkil ä Elli Hirvonen Aaro Haapaniemi Laura Tapiovaara Janne Pitk äniemi Nea Malila Antti M äkitie Source Type: research
Socioeconomic position and the pre-diagnostic interval among patients diagnosed with head and neck squamous cell carcinoma - a population-based study from DAHANCA
CONCLUSION: The interval from symptom onset to diagnosis and consultation patterns were similar across SEP groups. Still, socioeconomic differences in stage at diagnosis were observed for some - but not all - subsites.PMID:37672036 | DOI:10.1080/0284186X.2023.2254478
Source: Acta Oncologica - September 6, 2023 Category: Cancer & Oncology Authors: Maja Halgren Olsen Thomas Maltesen Pernille Lassen Trille Kristina Kjaer J ørgen Johansen Hanne Primdahl Elo Andersen Claus Andrup Kristensen Maria Andersen Mohammad Farhadi Jens Overgaard Susanne Oksbjerg Dalton Source Type: research
5-Fluorouracil and Anti-EGFR antibody scaffold chitosan-stabilized Pickering emulsion: Formulations, physical characterization, in-vitro studies in NCL-H226 cells, and in-vivo investigations in Wistar rats for the augmented therapeutic effects against squamous cell carcinoma
Int J Biol Macromol. 2023 Sep 4:126716. doi: 10.1016/j.ijbiomac.2023.126716. Online ahead of print.ABSTRACTThis research seeks to optimize a chitosan-stabilized Pickering emulsion (PE) containing 5-fluorouracil (5-FU) as a potential Squamous Cell Carcinoma therapy. The 5-Fluorouracil was also thoroughly analysed using UV spectrophotometry and RP-HPLC, demonstrating exceptional linearity, sensitivity, precision, and robustness. The techniques of characterization revealed Pickering emulsion (PE) morphology, solid-like gel properties, successful encapsulation, and promising anticancer effects. FTIR was used to validate the ef...
Source: International Journal of Biological Macromolecules - September 6, 2023 Category: Biochemistry Authors: Sankha Bhattacharya Prafull Shinde Amit Page Satyam Sharma Source Type: research
Pten knockout affects drug resistance differently in melanoma and kidney cancer
CONCLUSIONS: The results confirmed heterogenous cell responses to PTEN loss, which may lead to a better understanding of the role of PTEN in particular types of tumors and points to PTEN as a therapeutic target for personalized medicine.PMID:37673853 | DOI:10.1007/s43440-023-00523-y
Source: Pharmacological Reports - September 6, 2023 Category: Drugs & Pharmacology Authors: Klaudia Brodaczewska Aleksandra Majewska Aleksandra Filipiak-Duliban Claudine Kieda Source Type: research
Genome-wide association study of esophageal squamous cell cancer identifies shared and distinct risk variants in African and Chinese populations
Am J Hum Genet. 2023 Aug 29:S0002-9297(23)00283-5. doi: 10.1016/j.ajhg.2023.08.007. Online ahead of print.ABSTRACTEsophageal squamous cell carcinoma (ESCC) has a high disease burden in sub-Saharan Africa and has a very poor prognosis. Genome-wide association studies (GWASs) of ESCC in predominantly East Asian populations indicate a substantial genetic contribution to its etiology, but no genome-wide studies have been done in populations of African ancestry. Here, we report a GWAS in 1,686 African individuals with ESCC and 3,217 population-matched control individuals to investigate its genetic etiology. We identified a geno...
Source: Cancer Control - September 6, 2023 Category: Cancer & Oncology Authors: Wenlong Carl Chen Jean-Tristan Brandenburg Ananyo Choudhury Mahtaab Hayat Dhriti Sengupta Yaniv Swiel Chantal Babb de Villiers Lucien Ferndale Colleen Aldous Cassandra C Soo Sang Lee Charles Curtis Rob Newton Tim Waterboer Freddy Sitas Debbie Bradshaw Chr Source Type: research
Genomic and Transcriptomic Landscape of an Oral Squamous Cell Carcinoma Mouse Model for Immunotherapy
Cancer Immunol Res. 2023 Sep 5. doi: 10.1158/2326-6066.CIR-23-0133. Online ahead of print.ABSTRACTThe immune checkpoint inhibitor (ICI), anti-programmed death-1 (anti-PD-1), has shown moderate efficacy in some patients with head and neck squamous cell carcinoma (HNSCC). Because of this, it is imperative to establish a mouse tumor model to explore mechanisms of antitumor immunity and to develop novel therapeutic options. Here, we examined the 4-nitroquinoline-1-oxide (4NQO)-induced oral squamous cell carcinoma (OSCC) model for genetic aberrations, transcriptomic profiles, and immune cell composition at different pathologica...
Source: Cell Research - September 5, 2023 Category: Cytology Authors: Yi-Mei Lee Chia-Lang Hsu Yu-Hsin Chen Da-Liang Ou Chiun Hsu Ching-Ting Tan Source Type: research
Precise pattern of lymphatic spread of esophageal squamous cell carcinoma: results of 1074 patients with N1 disease
CONCLUSION: Bilateral recurrent nerve nodes, paraesophageal lymph nodes, and perigastric nodes were the most common sites of early lymph node metastasis. Esophageal squamous cell carcinoma involves more longitudinal than transverse lymph node metastases.PMID:37668800 | DOI:10.1007/s00432-023-05359-w
Source: Cell Research - September 5, 2023 Category: Cytology Authors: Kailin Lin Bin Li Yihua Sun Hong Hu Yawei Zhang Jiaqing Xiang Haiquan Chen Source Type: research
Assessing ChatGPT responses to common patient queries regarding basal cell carcinoma
Arch Dermatol Res. 2023 Sep 5. doi: 10.1007/s00403-023-02705-3. Online ahead of print.NO ABSTRACTPMID:37668714 | DOI:10.1007/s00403-023-02705-3
Source: Cell Research - September 5, 2023 Category: Cytology Authors: Megan H Trager Dawn Queen Lindsey A Bordone Larisa J Geskin Faramarz H Samie Source Type: research
A cell surface-binding antibody atlas nominates a MUC18-directed antibody-drug conjugate for targeting melanoma
Cancer Res. 2023 Sep 5. doi: 10.1158/0008-5472.CAN-23-1356. Online ahead of print.ABSTRACTRecent advances in targeted therapy and immunotherapy have substantially improved the treatment of melanoma. However, therapeutic strategies are still needed for unresponsive or treatment-relapsed melanoma patients. To discover antibody-drug conjugate (ADC)-tractable cell surface targets for melanoma, we developed an atlas of melanoma cell surface binding antibodies (pAbs) using a proteome-scale antibody array platform (PETAL). Target identification of pAbs led to development of melanoma cell killing ADCs against LGR6, TRPM1, ASAP1, a...
Source: Cell Research - September 5, 2023 Category: Cytology Authors: Jing Shi Tao Jiao Qian Guo Weining Weng Linjie Ma Qing Zhang Lijun Wang Jianjian Zhang Caiwei Chen Yaling Huang Mingqiao Wang Rong Pan Yanfang Tang Wenhao Hu Tao Meng Shu-Hui Liu Jun Guo Yan Kong Xun Meng Source Type: research
