Stridor After Tracheoesophageal Fistula Repair: Where Is the Lesion?
A male infant with a birthweight of 2,500 g (between the 3rd and 10th percentile) is born at 37 weeks ’ gestation to a 27-year-old primigravida woman with severe polyhydramnios (amniotic fluid index of 37 cm). After delivery, the neonate is vigorous, with Apgar scores of 8 and 9 at 1 and 5 minutes of age, respectively. He develops excessive frothy oral secretions, and the neonatology team is unabl e to pass a nasogastric tube. Chest radiography shows the coiling of a nasogastric tube with air in the stomach suggestive of esophageal atresia (EA) with tracheoesophageal fistula (TEF). (Source: NeoReviews recent issues)
Source: NeoReviews recent issues - January 1, 2022 Category: Pediatrics Source Type: news
Biostage Announces IND Approval from FDA for its Lead Product Candidate Cellspan(TM) Esophageal Implant
HOLLISTON, Mass., March 20, 2020 -- (Healthcare Sales & Marketing Network) -- Biostage, Inc. (OTCQB: BSTG) (Biostage or the Company), a bioengineering company developing next-generation esophageal implants, today announced that the U.S. Food and Drug Admi... Devices, Regenerative Medicine, FDA Biostage , esophageal implant, Cellspan Esophageal Implant, Esophageal Atresia (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - March 20, 2020 Category: Pharmaceuticals Source Type: news
Yorkton family worries after city left without pediatrician
Rachel Gregoire's daughter, Alice, has esophageal atresia, which means she regularly needs to see a pediatrician. But since Yorkton lost its only pediatrician in September, the Gregoire family now needs to drive to Regina every two weeks for appointments. (Source: CBC | Health)
Source: CBC | Health - December 10, 2019 Category: Consumer Health News Tags: News/Canada/Saskatchewan Source Type: news
What Are the Types of Tracheoesophageal Fistulas?
Discussion
Respiratory problems in infants can caused by many things including any type of obstruction from the nose to lung. Neonates and infants are particularly susceptible to changes in the size of the airway because of the physics of airflow resistance. Important reminders about infant airways:
Resistance = 1/radius4 (Poiseuille’s equation) therefore even a 1 mm decrease in the airway circumferences increases the airflow resistance x16.
Increased airflow causes less pressure along the walls, which can lead to collapse of the walls (Bernoulli’s and Venturi effects).
Neonates have smaller lungs relative to ...
Source: PediatricEducation.org - March 4, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
Robot operates on a two-day-old baby who was born missing an esophagus
The two-day old baby was born in Chandigarh, India, on January 31 without a fully-formed esophagus, which carries food and liquids from the mouth to the stomach, known as esophageal atresia. (Source: the Mail online | Health)
Source: the Mail online | Health - February 20, 2019 Category: Consumer Health News Source Type: news
Biostage awarded $1.1 million Phase II NIH SBIR Fast-Track grant to develop Cellspan(TM) Esophageal Implant (CEI) as a novel treatment for pediatric esophageal atresia
These nondilutive funds support development, testing and IND submission of the Company's pediatric esophageal implant candidate
HOLLISTON, Mass., Nov. 6, 2018 -- (Healthcare Sales & Marketing Network) -- Biostage, Inc. (OTCQB: BSTG), a b... Regenerative Medicine Biostage, Cellspan, Esophageal Implant, Cellframe, esophageal atresia (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - November 6, 2018 Category: Pharmaceuticals Source Type: news
What is the Difference Between an Association and a Syndrome?
Discussion
VATER association was first described in the 1970s with additional congenital malformations being added to the association so it is most often called VACTERL association. It is a highly heterogeneous, overlapping condition estimated to occur in ~1/10,000-40,000 births. The cause is unknown. In animal models, some signaling pathway gene mutations have phenotypes of VACTERL association.
Experts suggest that patients having at least 2 components should be further evaluated (at least 3 for diagnosis) for VACTERL and other diseases in its differential diagnosis. There are more than 30 syndromes, mutations and diseas...
Source: PediatricEducation.org - February 5, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
New robot can help treat rare birth defect
(University of Sheffield) Researchers at the University of Sheffield and Boston's Children Hospital, Harvard Medical School have created a robot that can be implanted into the body to aid the treatment of oesophageal atresia, a rare birth defect that affects a baby's oesophagus. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 18, 2018 Category: International Medicine & Public Health Source Type: news
Study: Implantable robot helps spur tissue regeneration
An implantable, programmable robot induced cell growth and lengthened part of the esophagus in an animal model by more than 75%, according to researchers from Boston Children’s Hospital.
The team reported in Science Robotics today that the robot triggered tissue growth without interfering with organ function. The system could help regrow parts of the esophagus that are missing in people with long-gap esophageal atresia, the researchers noted.
“This project demonstrates proof-of-concept that miniature robots can induce organ growth inside a living being for repair or replacement, while avoiding the sedation and...
Source: Mass Device - January 11, 2018 Category: Medical Devices Authors: Sarah Faulkner Tags: Implants Regenerative Medicine Research & Development Robotics Boston Children's Hospital Source Type: news
The joy of cooking (and eating) after tracheomalacia
For most little kids, a trip to the supermarket is an annoying chore, made tolerable only by the opportunity to request sugary snacks as a reward. But when Charlotte McQueen accompanies her mother, Erin, to the store, it’s a journey marked by imagination and delight. “Mom, can we get that?” she asks, pointing to a can of pureed pumpkin. “Oh, and we’ll need marshmallows and we can make chocolate frosting. It will be a great cake!”
At nearly 5 years old, Charlotte is an avid baker — a talent she picked up not at culinary school, but at the Yawkey Family Inn. There, a volunteer taught her and other chronically i...
Source: Thrive, Children's Hospital Boston - January 10, 2018 Category: Pediatrics Authors: Jessica Cerretani Tags: Diseases & Conditions Our Patients’ Stories Dori Gallagher Dr. Michael Manfredi Dr. Russell Jennings Esophageal and Airway Treatment Center esophageal atresia and tracheoesophageal fistula posterior tracheopexy tracheomalacia Yawkey Fa Source Type: news
Isaac ’s story: A ‘new normal’ with short bowel syndrome
It was the morning after their baby son Isaac had come home from the hospital, and Jennifer and Brian Campbell were performing the same sweet act of bonding as many new parents: giving him a bath in the sink. But as they maneuvered around the room, they suddenly realized something was very wrong. “I fell to the floor and started screaming and crying as formula shot out of his stomach,” remembers Jennifer. “I thought we’d broken him.”
The reality, of course, was that the Campbells were simply adjusting to their new “normal” — something any parent of a medically complex child can understand. Isaac wasn’t a ...
Source: Thrive, Children's Hospital Boston - December 14, 2017 Category: Pediatrics Authors: Jessica Cerretani Tags: Diseases & Conditions Our Patients’ Stories Center for Advanced Intestinal Rehabilitation cerebral palsy Dr. Christopher Duggan Dr. Mark Puder Dr. Tom Jaksic necrotizing enterocolitis short bowel syndrome (SBS). Source Type: news
Fetal care team heals baby boy
The Fetal Care Center, a partnership between Yale Medicine and Yale New Haven Children ' s Hospital, developed a plan to cure the baby ' s esophageal atresia. (Source: Yale Science and Health News)
Source: Yale Science and Health News - October 16, 2017 Category: Universities & Medical Training Source Type: news
Cook Medical recalls select Zenith Alpha endo grafts
The FDA today released information on a recall of Cook Medical’s Zenith Alpha thoracic endovascular graft designed for treating blunt traumatic aortic injury over issues with thrombus formation, classifying the recall as Class I.
Class I recall designations, the FDA’s most serious classification of recall, are used when there is a reasonable probability that product use could cause serious adverse health consequences or death.
The Zenith Alpha thoracic endovascular graft is designed to treat isolated lesions in main blood vessels that carry blood from the heart through the chest into the abdomen, and is used in patient...
Source: Mass Device - August 16, 2017 Category: Medical Devices Authors: Fink Densford Tags: Recalls Vascular Cook Medical Source Type: news
An ocean away: Care for laryngeal cleft brings Clara to Boston
My husband, Duncan, and I were living in London, England, when Clara was born. Although my pregnancy had started out like any other, I later developed severe polyhydramnios, an accumulation of amniotic fluid that can sometimes indicate the presence of certain congenital issues.
After I delivered, it became clear that Clara had a congenital condition called esophageal atresia with tracheoesophageal fistula (EA/TEF). This condition meant that her esophagus (the tube that carries food from the mouth to the stomach) hadn’t developed properly and didn’t connect to her stomach, but that her esophagus and windpipe were improp...
Source: Thrive, Children's Hospital Boston - July 11, 2017 Category: Pediatrics Authors: Natascha Kiernan Tags: Diseases & Conditions Our Patients’ Stories Center for Airway Disorders Dr. Reza Rahbar laryngeal cleft Source Type: news
Real Stories Of Americans Who Will Be Affected By The Proposed Changes To The ACA — And What YOU Can Do To Fight
With the proposed changes to the Affordable Care Act (ACA), 20 million Americans are at risk of losing their health care coverage.
A survey, conducted by Brunswick Partners, found that “75 percent of Americans agree that the proposed changes to Medicaid in the AHCA are a bad idea. And that we should not allow 14 million Americans to become uninsured even if there is a potential to reduce Medicaid spending. These results are significant because they find majorities of Americans identifying as conservatives (55 percent), moderates (82 percent) and liberals (90 percent) are opposed to the AHCA’s Medicaid pro...
Source: Healthy Living - The Huffington Post - June 21, 2017 Category: Consumer Health News Source Type: news
