What is the Difference Between an Association and a Syndrome?

Discussion VATER association was first described in the 1970s with additional congenital malformations being added to the association so it is most often called VACTERL association. It is a highly heterogeneous, overlapping condition estimated to occur in ~1/10,000-40,000 births. The cause is unknown. In animal models, some signaling pathway gene mutations have phenotypes of VACTERL association. Experts suggest that patients having at least 2 components should be further evaluated (at least 3 for diagnosis) for VACTERL and other diseases in its differential diagnosis. There are more than 30 syndromes, mutations and diseases that have components of the malformations in VACTERL association. Alagille syndrome , CHARGE Syndrome, Blackfan-Diamond anemia, Holt-Oram syndrome, and Caudal regression syndrome are just a few examples. All signs and symptoms can be obvious or extremely subtle. Some symptoms may not occur until years later or be surreptitious. Most patients do not have all of the components. Facial and brain malformations are not common with VACTERL association. Treatment depends on the specific malformations and their extensiveness. Surgical treatment is often necessary to manage one or more problems. Components of the VACTERL association include: Vertebral malformation Occurs in 60-90% of patients Usually segmentation defects, can occur in any vertebrae Can also have rib anomalies and/or spinal curvature Can also have tethered cord and/or similar neurological anomal...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news

Related Links:

In this study, we aimed to investigate the incidence of Dientamoeba fragilis with different diagnostic methods in patients with gastrointestinal symptoms and determine the sensitivity and specificity of existing diagnostic methods. Fecal samples collected from 101 patients with gastrointestinal complaints (especially upper abdominal pain, abdominal and pelvic pain, nausea and vomiting, gastroenteritis and colitis, unexplained fever and diarrhea) and 20 control cases from various clinics were included in the study. Samples were first examined with native-Lugol (N-L) method and cultured in Robinson medium. All 121 stool and ...
Source: Mikrobiyoloji Bulteni - Category: Microbiology Tags: Mikrobiyol Bul Source Type: research
Source: BMJ Comments - Category: General Medicine Source Type: forums
CONCLUSION: Renal diseases and some of the main related diseases corresponded to 12.97% of the expenses in the triennium 2013-2015, and RRT to more than 5% of the SUS expenses with medium and high complexity healthcare. Such high expenses determine great concerns on the future maintenance of treatment for stage-5 CKD in Brazil and countries in similar or worse conditions of development. PMID: 29927463 [PubMed - as supplied by publisher]
Source: Jornal Brasileiro de Nefrologia - Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
CONCLUSION: There was a significant increase in the number of transplants, with evolution in graft survival, despite the worsening in the profiles of recipients and donors. PMID: 29927459 [PubMed - as supplied by publisher]
Source: Jornal Brasileiro de Nefrologia - Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
CONCLUSION: This analysis confirmed that in this population, infection is the leading cause of mortality over the first 5 years after kidney transplantation. Several demographic and socioeconomic risk factors were associated with death, most of which are not readily modifiable. PMID: 29927458 [PubMed - as supplied by publisher]
Source: Jornal Brasileiro de Nefrologia - Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
CONCLUSION: There was a change in the respiratory function of single port workers, which may be related to the exposure to fertilizers. PMID: 29933416 [PubMed - in process]
Source: Revista gaucha de enfermagem EENFUFRGS - Category: Nursing Tags: Rev Gaucha Enferm Source Type: research
CONCLUSIONS: Pleasure at work for the studied teams was associated with freedom of expression, achievement, and professional recognition, and pain was related to professional exhaustion and work overload. PMID: 29933414 [PubMed - in process]
Source: Revista gaucha de enfermagem EENFUFRGS - Category: Nursing Tags: Rev Gaucha Enferm Source Type: research
Conclusion: Most of the results of lower abdominal ultrasound in the patients sent for whole abdominal ultrasound were negative, and the majority of the positive findings were benign conditions requiring no further management. More positive results, especially findings suggestive or suspicious of cancers, were seen in cases with positive clinical data. Routine use of whole abdominal ultrasound does not appear to be very helpful, especially in patients who have no symptoms in the lower abdomen. PMID: 29927560 [PubMed - in process]
Source: Journal of the Medical Association of Thailand = Chotmaihet thangphaet - Category: General Medicine Tags: J Med Assoc Thai Source Type: research
Authors: Kovavisarach E, Sukontaman W Abstract Background: Pregnant women who prefer cesarean delivery may request it without any obstetric indication, and this could be one of the reasons for the high rates of cesarean deliveries. Objective: To determine the route of delivery preferred by Thai pregnant women. Material and Method: A cross-sectional study was performed of Thai pregnant women who attended the antenatal care (ANC) clinic in Rajavithi Hospital between February 1, 2011 and July 31, 2011. Participants were interviewed by one of the researchers using questionnaires relating to their preferred rout...
Source: Journal of the Medical Association of Thailand = Chotmaihet thangphaet - Category: General Medicine Tags: J Med Assoc Thai Source Type: research
Conclusion: Both surgical techniques showed improvement in overall spinal alignment; however, no significant difference between these improvements was found in the two groups. PMID: 29927228 [PubMed - in process]
Source: Journal of the Medical Association of Thailand = Chotmaihet thangphaet - Category: General Medicine Tags: J Med Assoc Thai Source Type: research
More News: Anemia | Atresia | Back Curves | Back Pain | Brain | Cardiology | Cardiovascular | Constipation | CT Scan | Databases & Libraries | Disability | Electrocardiogram | Environmental Health | Esophageal Atresia | Faconi Anemia | Gastroenterology | Genetics | Heart | Heart Transplant | Hematology | Hydrocephalus | Incontinence | Intensive Care | Internet | Learning | MRI Scan | Nasogastric Intubation | Neurology | Pain | Pediatrics | Radiography | Respiratory Medicine | Scoliosis | Study | Tracheo-Esophageal Fistula | Transplants | Ultrasound | Universities & Medical Training