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The joy of cooking (and eating) after tracheomalacia

For most little kids, a trip to the supermarket is an annoying chore, made tolerable only by the opportunity to request sugary snacks as a reward. But when Charlotte McQueen accompanies her mother, Erin, to the store, it’s a journey marked by imagination and delight. “Mom, can we get that?” she asks, pointing to a can of pureed pumpkin. “Oh, and we’ll need marshmallows and we can make chocolate frosting. It will be a great cake!” At nearly 5 years old, Charlotte is an avid baker — a talent she picked up not at culinary school, but at the Yawkey Family Inn. There, a volunteer taught her and other chronically ill kids how to bake while they waited to undergo treatment at Boston Children’s Hospital. Today, it’s not only impressive that she can bake a cake, but also that she can eat it. For the first several years of her life, Charlotte couldn’t eat by mouth. In fact, she couldn’t even breathe on her own. A scary turn of events “We wanted a home birth,” remembers Erin. “It went smoothly, but then things started going downhill fast.” Charlotte stopped breathing and had to be rushed to a hospital near their home in Las Vegas, Nevada. Once there, she continued to have episodes of apnea and was transported to another local hospital for care. When a clinician there tried to insert a nasogastric (NG) tube, which typically runs through the nose and down the throat into the stomach, Erin and her hus...
Source: Thrive, Children's Hospital Boston - Category: Pediatrics Authors: Tags: Diseases & Conditions Our Patients’ Stories Dori Gallagher Dr. Michael Manfredi Dr. Russell Jennings Esophageal and Airway Treatment Center esophageal atresia and tracheoesophageal fistula posterior tracheopexy tracheomalacia Yawkey Fa Source Type: news

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Our concerns about the meta-analysis of procalcitonin-guided therapy in patients with acute respiratory infections by Philipp Schuetz and colleagues1 go well beyond those expressed in an accompanying Comment.2 We fear that physicians will infer that antibiotic treatment can be given to or withheld from patients with community-acquired pneumonia on the basis of plasma procalcitonin concentrations.
Source: The Lancet Infectious Diseases - Category: Infectious Diseases Authors: Tags: Correspondence Source Type: research
We share, in principal, the concern of Ishan Kamat and colleagues that the diagnosis of community-acquired pneumonia is challenging, and that procalcitonin should not be used as a substitute for good clinical practice. Decisions regarding the potential benefit of starting antibiotic treatment in patients presenting with lower respiratory tract illnesses should be based on all available clinical and diagnostic parameters, including a thorough clinical assessment.
Source: The Lancet Infectious Diseases - Category: Infectious Diseases Authors: Tags: Correspondence Source Type: research
Conclusions: Maternal influenza immunization may reduce severe pneumonia episodes among infants—particularly those too young to be completely vaccinated against Streptococcus pneumoniae and influenza.
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Original Studies Source Type: research
We report on a 20-year-old patient with MECP2 duplication syndrome, IgG2/IgG4/IgA/IgM deficiency and polysaccharide-specific antibody deficiency, who had 46 episodes of pneumonia in his first 13 8/12 years of life. Immunoglobulin substitution, daily antibiotic prophylaxis with two agents and supportive measures reduced occurrence of pneumonia to four episodes in the following 6 2/12 years of life.
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Immunology Reports Source Type: research
Conclusion: Previous history of respiratory diseases, family history of chronic respiratory diseases, previous dusty working environment, smoking, and service years were determinants of chronic respiratory symptoms. Public health endeavors to prevent the burden of chronic respiratory symptoms among pharmaceutical factory workers should target the reduction of adverse workplace exposures and discouragement of smoking. PMID: 29666655 [PubMed]
Source: Journal of Tropical Medicine - Category: Tropical Medicine Tags: J Trop Med Source Type: research
Conclusions: Although continuous SSD did not reduce the incidence of VAP, it reduced the length of mechanical ventilation and ICU stay when compared to intermittent SSD. PMID: 29662613 [PubMed]
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
Discussion and conclusion The urethral duplication is an anomaly that has multiple anatomical presentations. There are several theories about the etiology, but none can explain all types of presentations. There is also more than one rating available, and the Effmann classification is the most detailed. The case exemplifies this varied spectrum of anatomic urethral duplication. It resembles the urethral duplication type IIa-Y, however, ventral urethra meatus was located in penoscrotal area and both urethras were at least partially hypoplastic/dysplastic associated with obstruction and bladder retention. In determining how t...
Source: International Braz J Urol - Category: Urology & Nephrology Source Type: research
Discussion and conclusion The urethral duplication is an anomaly that has multiple anatomical presentations. There are several theories about the etiology, but none can explain all types of presentations. There is also more than one rating available, and the Effmann classification is the most detailed. The case exemplifies this varied spectrum of anatomic urethral duplication. It resembles the urethral duplication type IIa-Y, however, ventral urethra meatus was located in penoscrotal area and both urethras were at least partially hypoplastic/dysplastic associated with obstruction and bladder retention. In determining how t...
Source: International Braz J Urol - Category: Urology & Nephrology Source Type: research
Discussion and conclusion The urethral duplication is an anomaly that has multiple anatomical presentations. There are several theories about the etiology, but none can explain all types of presentations. There is also more than one rating available, and the Effmann classification is the most detailed. The case exemplifies this varied spectrum of anatomic urethral duplication. It resembles the urethral duplication type IIa-Y, however, ventral urethra meatus was located in penoscrotal area and both urethras were at least partially hypoplastic/dysplastic associated with obstruction and bladder retention. In determining how t...
Source: International Braz J Urol - Category: Urology & Nephrology Source Type: research
We present two cases of renal transplant patients who had severe hypoxemic respiratory failure due to P. jirovecii six years after transplantation. In addition to steroids, they received treatment with trimethoprim-sulfamethoxazole. One patient died, while the other had clinical recovery, with preservation of the renal graft function. PMID: 29668131 [PubMed - in process]
Source: Biomedica : Revista del Instituto Nacional de Salud - Category: International Medicine & Public Health Tags: Biomedica Source Type: research
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