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Case Report: Granulomatous Amebic Encephalitis due to Acanthamoeba spp. in an Immunocompetent Pediatric Patient
Am J Trop Med Hyg. 2021 May 10:tpmd210129. doi: 10.4269/ajtmh.21-0129. Online ahead of print.ABSTRACTGranulomatous amebic encephalitis (GAE) caused by Acanthamoeba is a rare infection with central nervous system (CNS) involvement usually with fatal consequences. Currently, information regarding GAE in children is scarce and is limited only to case reports and case series. A 13-year-old immunocompetent male patient with a 6-month history of progressive and intermittent headaches presented to our institution. One week before hospital admission, the patient showed signs of CNS involvement. Magnetic resonance imaging revealed ...
Source: The American Journal of Tropical Medicine and Hygiene - May 10, 2021 Category: Tropical Medicine Authors: Denisse Vaquera Aparicio Jos é Iván Castillo Bejarano Abiel Mascare ñas de Los Santos Sergio Ram írez-Cortinas Manuel de la O Cavazos Source Type: research

Tick Paralysis Case Series: An 11-Year Institutional Case Series
Conclusions The incidence of tick paralysis in southern Louisiana is unknown. However, our case series indicates that it is likely higher than expected. Although most cases in our facility were quickly diagnosed and treated through tick removal, delayed diagnosis results in unnecessary tests, procedures, and medical costs. All of our cases fully recovered after tick removal.
Source: Pediatric Emergency Care - December 1, 2021 Category: Emergency Medicine Tags: Original Articles Source Type: research

What predicts persisting social impairment following pediatric traumatic brain injury: contribution of a biopsychosocial approach
CONCLUSIONS: We identified five distinct social recovery trajectories post-child-TBI, each characterized by a unique biopsychosocial profile, highlighting the importance of comprehensive social assessment and understanding of factors contributing to social impairment, to target resources and interventions to children at highest risk.PMID:35189999 | DOI:10.1017/S0033291722000186
Source: Psychological Medicine - February 22, 2022 Category: Psychiatry Authors: Vicki Anderson Stephen J C Hearps Cathy Catroppa Miriam H Beauchamp Nicholas P Ryan Source Type: research

A study on the distinctive clinical profile and thrombophilia in pediatric cerebral venous sinus thrombosis
Conclusion: Pediatric CVST is uncommon and has a different spectrum from adults, with unique clinical triggers and thrombophilic states. Management varies significantly among clinicians, due to the paucity of trial evidence and also due to the heterogeneity of this condition in children.
Source: Journal of Pediatric Neurosciences - June 3, 2022 Category: Neuroscience Authors: Nevine Ismail Ray Clarke Cheri Mathews John Ravi K Anadure Source Type: research

Clinical Practice Patterns of Isthmic Spondylolysis in Young Athletes: A Survey of Pediatric Research in Sports Medicine Members
Isthmic spondylolysis is a common cause of back pain in young athletes. The condition presents to numerous medical providers who employ a variety of different practices in diagnosis and management. The purpose of this study was twofold: to review the literature of diagnosis and management of the young athlete with isthmic spondylolysis and to survey Pediatric Research in Sports Medicine (PRiSM) members during the 2021 PRiSM Annual Meeting on practice patterns of diagnosis and management of the young athlete with isthmic spondylolysis. The response rate was 27%. Per respondents: 24% obtain oblique radiographs; 90% use magne...
Source: Current Sports Medicine Reports - November 1, 2022 Category: Sports Medicine Tags: Special Communication Source Type: research

MRI Anatomy of the Tibial ACL Attachment and Proximal Epiphysis in a Large Population of Skeletally Immature Knees: Reference Parameters for Planning Anatomic Physeal-Sparing ACL Reconstruction
Conclusion: The center of the ACL tibial attachment was consistently near 51% of the anteroposterior diameter, regardless of age or sex. The vertical depth of the tibial epiphysis was ~16 mm in adolescents. Maximum oblique depth from ACL attachment was ~30 mm, occurring at a mean angle ~50° regardless of age or sex. The normative values for tibial ACL attachment and epiphyseal anatomy presented here may be helpful in selecting candidates for surgery and in planning surgical approaches for pediatric ACL reconstruction.
Source: The American Journal of Sports Medicine - June 30, 2014 Category: Sports Medicine Authors: Swami, V. G., Mabee, M., Hui, C., Jaremko, J. L. Tags: Knee ligaments, ACL, Imaging, magnetic resonance, Pediatric sports medicine Source Type: research

Amplitude-integrated EEG in newborns with critical congenital heart disease predicts preoperative brain MRI findings
The study aims are to evaluate cerebral background patterns using amplitude-integrated electroencephalography (aEEG) in newborns with critical congenital heart disease (CHD), determine if aEEG is predictive of preoperative brain injury and assess the incidence of preoperative seizures. We hypothesize that aEEG will show abnormal background patterns in the early preoperative period in infants with CHD that have preoperative brain injury on magnetic resonance imaging (MRI).
Source: Pediatric Neurology - March 4, 2015 Category: Neurology Authors: Sarah B. Mulkey, Vivien L. Yap, Shasha Bai, Raghu H. Ramakrishnaiah, Charles M. Glasier, Renee A. Bornemeier, Michael L. Schmitz, Adnan T. Bhutta Tags: Original Articles Source Type: research

Children's distress during magnetic resonance imaging procedures.
Authors: Tyc VL, Fairclough D, Fletcher B, Leigh L, Mulhern RK Abstract We investigated the epidemiology of pediatric anxiety and distress associated with magnetic resonance imaging procedures (MRIPs). Scores on the State-Trait Anxiety Inventory (Spielberger, Gorsuch, Lushene, Vagg, & Jacobs, 1983) and the State-Trait Anxiety Inventory for Children (Spielberger, Edwards, Lushene, Montuori, & Platzek, 1973), and subjective ratings of distress associated with MRIP were obtained from 55 pediatric oncology patients and their parents. Approximately 30% of children and their parents reported that MRIP produced si...
Source: Children's Health Care - November 26, 2015 Category: Pediatrics Tags: Child Health Care Source Type: research

A pediatric institutional acute stroke protocol improves timely access to stroke treatment
AimWe aimed to evaluate whether an institutional acute stroke protocol (ASP) could accelerate the diagnosis and secondary treatment of pediatric stroke. MethodWe initiated an ASP in 2005. We compared 209 children (125 males, 84 females; median age 4.8y, interquartile range [IQR] 1.2–9.3y, range 0.09–17.7y) diagnosed with arterial ischemic stroke ‘pre‐protocol’ (1992–2004) to 112 children (60 males, 52 females; median age 5.8y, IQR 1.0–11.4y, range 0.08–17.7y) diagnosed ‘post‐protocol’ (2005–2012) for time‐to‐diagnosis, mode of diagnostic imaging, and time‐to‐treatment with antithrombotic med...
Source: Developmental Medicine and Child Neurology - July 31, 2016 Category: Child Development Authors: Melissa Shack, Andrea Andrade, Priyanka P Shah ‐Basak, Manohar Shroff, Mahendranath Moharir, Ivanna Yau, Rand Askalan, Daune MacGregor, Mubeen F Rafay, Gabrielle A deVeber Tags: Original Article Source Type: research

What makes a good pediatric transplant lung: Insights from in vivo lung morphometry with hyperpolarized 3He magnetic resonance imaging
The objective of this study was to evaluate the use of an innovative non‐invasive technique, in vivo lung morphometry with hyperpolarized ³He MRI—to characterize lung microstructure in the pediatric lung transplant population. This technique yields quantitative measurements of acinar airways’ (alveolar ducts and sacs) parameters, such as acinar airway radii and alveolar depth. Six pediatric lung transplant recipients with cystic fibrosis underwent in vivo lung morphometry MRI, pulmonary function testing, and quantitative CT. We found a strong correlation between lung lifespan and alveolar depth—patients with more ...
Source: Pediatric Transplantation - November 30, 2016 Category: Transplant Surgery Authors: Emily F. Fishman, James D. Quirk, Stuart C. Sweet, Jason C. Woods, David S. Gierada, Mark S. Conradi, Marilyn J. Siegel, Dmitriy A. Yablonskiy Tags: ORIGINAL ARTICLE Source Type: research

Prevalence of Discoid Meniscus During Arthroscopy for Isolated Lateral Meniscal Pathology in the Pediatric Population
Conclusions: In conclusion, discoid menisci have a high prevalence in isolated lateral meniscus pathology requiring knee arthroscopy. Clinical presentation, imaging, characteristics, and treatment may be different among different age groups. In the adolescent age group (14 to 16 y old), the presentation of a discoid meniscus may not be different from a meniscus tear with normal morphology. Level of Evidence: Level III—diagnostic.
Source: Journal of Pediatric Orthopaedics - May 9, 2017 Category: Orthopaedics Tags: Knee Source Type: research

Value of dynamic magnetic resonance imaging in preoperative evaluation of pediatric osteosarcoma
Conclusions DCE-MRI can be used preoperatively as a sensitive, specific, and non-invasive method for detection of viability and necrosis within osteosarcoma.
Source: The Egyptian Journal of Radiology and Nuclear Medicine - May 18, 2017 Category: Nuclear Medicine Source Type: research

Recent Advances and Trends in Pediatric Cardiac Imaging
AbstractCardiac imaging is central to today ’s pediatric cardiology practice not only to diagnose structural congenital defects and delineate cardiac and extracardiac anatomy but also for determining the hemodynamic impact of the structural defects and acquired pediatric diseases. Not so long ago, clinicians had to heavily rely on angiograp hy as the main cardiac imaging modality to visualize the heart. Particularly, the development of echocardiography in the 1970s and 1980s together with the development of magnetic resonance imaging (MRI) and computed tomography (CT) resulted in a non-invasive diagnostic revolution with...
Source: Current Treatment Options in Cardiovascular Medicine - February 21, 2018 Category: Cardiology Source Type: research