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Total 21872 results found since Jan 2013.

Outcomes of Severe Seronegative Hepatitis-associated Aplastic Anemia: A Pediatric Case Series
Conclusions: We found that ATG-based IST induced remission of hepatitis in patients with steroid-refractory HAAA. This is also an appropriate initial treatment for severe Aplastic Anemia, though may not prevent the need for HSCT. We propose that equine ATG based IST at standard dosing regimen for sAA is a therapy that in select cases can be considered early on in the treatment course and could lead to a sustained remission of both hepatitis and sAA. This should be considered in collaboration with a pediatric hematologist.
Source: Journal of Pediatric Gastroenterology and Nutrition - January 30, 2021 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Extracorporeal renal and liver support in pediatric acute liver failure
AbstractThe liver is the only organ which can regenerate and, thus, potentially negate the need for transplantation in acute liver failure (ALF). Cerebral edema and sepsis are leading causes of mortality in ALF. Both water-soluble and protein-bound toxins have been implicated in pathogenesis of various ALF complications. Ammonia is a surrogate marker of water-soluble toxin accumulation in ALF and high levels are associated with higher grades of hepatic encephalopathy, raised intracranial pressure, and mortality. Therefore, extracorporeal therapies aim to lower ammonia and maintain fluid balance and cytokine homeostasis. Th...
Source: Pediatric Nephrology - March 30, 2021 Category: Urology & Nephrology Source Type: research

Use of the Molecular Adsorbent Recirculating System in Acute Liver Failure: Results of a Multicenter Propensity Score-Matched Study*
CONCLUSIONS: Treatment with molecular adsorbent recirculating system is associated with increased 21-day transplant-free survival in acute liver failure and improves biochemical variables and hemodynamics, particularly in acetaminophen-acute liver failure.
Source: Critical Care Medicine - February 1, 2022 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

Perfusion Machine Restores Donor Liver for Transplant
Clinical researchers at the University of Zurich in Switzerland have created a perfusion machine to store donor livers before transplant. We originally reported on the machine back in 2020, but now the team has announced that they stored and treated ...
Source: Medgadget - June 7, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Anesthesiology Critical Care Medicine Pathology Surgery liver transplant Liver4Life transplantation UZH_en Source Type: blogs

Persistent But Not Transient Acute Kidney Injury Was Associated With Lower Transplant-Free Survival in Patients With Acute Liver Failure: A Multicenter Cohort Study*
CONCLUSIONS: In a multicenter cohort of patients with ALF, persistent but not transient AKI was independently associated with lower short-term TFS.
Source: Critical Care Medicine - August 24, 2022 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

Bill Clinton, Paid to Speak to Biotech Conference, Extolled $1000 Pill to Prevent "Liver Rot," Despite Lack of Evidence that It Does
ConclusionHow distorted is health care these days.  Misinformation, even disinformation seems to dominate evidence and logic.  Concerns about health care dysfunction are suppressed by the anechoic effect.  Perhaps inspired by the generic managers who now run health care organizations, everyone seems to have become a health care expert, and so the reach of viewpoints on health care seems to be more about the celebrity of their proponents rather than their knowledge, or the logic and evidence underlying their views.As a start, true health care reform has to somehow liberate good clinical evidence from where it...
Source: Health Care Renewal - July 1, 2015 Category: Health Management Tags: Clinton Foundation evidence-based medicine Gilead hepatitis C Sovaldi Source Type: blogs

FDG PET/CT Findings of the Recurrent Posttransplantation Lymphoproliferative Disorder in a Pediatric Liver Transplant Recipient With Right Leg Pain as the Only Complaint
We report a case of a pediatric patient with recurrent PTLD after liver transplantation, whose only complaint was right tibial pain. FDG PET/CT revealed not only hypermetabolic activity in the right proximal tibia but also in many other parts of the body. Recurrent PTLD was confirmed after bone biopsy.
Source: Clinical Nuclear Medicine - September 12, 2015 Category: Nuclear Medicine Tags: Interesting Images Source Type: research

Why Patient Voices Are Important
Editor’s Note: Be sure to check out the collection of articles in the March issue and our new blog content for more on the patient voice in medicine. I used to live on a short dirt road where everyone knew everyone else. We recognized each others’ children and would often share childcare responsibilities. A part of our extended neighborhood family for me included occasional medical consultations. I would hear about a neighbor’s call to his doctor to be seen for a cough and fever and the appointment that could not be scheduled for a week. I would bring my stethoscope over to the neighbor’s house to see if he really ...
Source: Academic Medicine Blog - March 22, 2016 Category: Universities & Medical Training Authors: David P. Sklar, M.D. Tags: Featured From the Editor listening to patients patient centered care patient voice physician-patient relationship Source Type: blogs

10 New Jobs in the Future of Healthcare and Medicine – Part I.
Disruptive technologies will transform the healthcare job market. Although some tasks and positions will become obsolete, new medical professions will gain ground. Organ designers, robot companion technicians and telesurgeons in the first part of our article series. Profession re-design: in progress As in the era of the various Industrial Revolutions, many people are currently afraid that robots and artificial intelligence will take their jobs. It is without doubt that disruptive technologies are changing healthcare, medicine and pharma, as well as the way we gather medical information or how we interact with medical profe...
Source: The Medical Futurist - February 2, 2017 Category: Information Technology Authors: nora Tags: Future of Medicine artificial intelligence cryonics deep learning driverless car healthcare jobs Innovation medical drones Personalized medicine robotics technology telehealth Source Type: blogs

3D Printing in Medicine And Healthcare: Amazing Equipment And Biomaterials We Can Print Out Today
3D printing has demonstrated huge potential for the future of medicine in the previous years, and its development is unstoppable. Just look at the impressive list of 3D printed healthcare materials and medical equipment below! How does 3D printing work? 3D printing is part of the innovative process called additive manufacturing, which means the production of three dimensional solid objects from a digital file. The printer uses a kind of layering process, by which one layer is added after the other until you have a fully formed object. It allows designers and engineers to create complex parts for cars, machines or airplan...
Source: The Medical Futurist - April 11, 2017 Category: Information Technology Authors: TMF Tags: 3D Printing in Medicine Future of Medicine 3d printed biomaterial bioprinting GC1 Health Healthcare Innovation medical technology tissue engineering Video Source Type: blogs

The Ultimate List of What We Can 3D Print in Medicine And Healthcare!
3D printing has demonstrated huge potential for the future of medicine in the previous years, and its development is unstoppable. Just look at the impressive list of 3D printed healthcare materials and medical equipment below! How does 3D printing work? 3D printing is part of the innovative process called additive manufacturing, which means the production of three dimensional solid objects from a digital file. The printer uses a kind of layering process, by which one layer is added after the other until you have a fully formed object. It allows designers and engineers to create complex parts for cars, machines or airplan...
Source: The Medical Futurist - April 11, 2017 Category: Information Technology Authors: TMF Tags: 3D Printing in Medicine Future of Medicine 3d printed biomaterial bioprinting GC1 Health Healthcare Innovation medical technology tissue engineering Video Source Type: blogs

From Death to Health in 30 Days: A Hemochromatosis Case Report
Discussion The uniqueness of this case illustrates the crucial role of a health care team that persisted in differentiating the patient’s diagnosis and continued to sustain both physical and emotional care throughout his hospitalization despite a poor prognosis. The patient felt support from this team during the course of his illness, from requiring life-supporting care in intensive care unit to returning home and resuming his normal activities of daily living.
Source: Dimensions of Critical Care Nursing - August 2, 2018 Category: Nursing Tags: Clinical DIMENSION Source Type: research

Researchers discover a genetic defect linked to pediatric liver disease
(University of Colorado Anschutz Medical Campus) Researchers from the University of Colorado Anschutz Medical Campus, in collaboration with several other institutions, have discovered a genetic defect linked to biliary atresia (BA), the most common pediatric cause of end-stage liver disease, and the leading indication for liver transplantation in children.
Source: EurekAlert! - Medicine and Health - February 21, 2019 Category: International Medicine & Public Health Source Type: news

Post-traumatic stress disorder in living donors after pediatric liver transplantation: A cross-sectional investigation study
Liver transplantation can lead to post-traumatic stress disorder (PTSD) in recipients, but the risk factors associated with PTSD in living donors are unknown. To investigate this progression in pediatric living donors, a cross-sectional investigation was carried out. All participants completed 2 questionnaires: a PTSD self-rating scale (PTSD-SS) and a validated Chinese version of the Medical Outcomes Study Short Form-36 (SF-36). Clinical and demographic data were collected from medical records and self-report questionnaires. Univariate analysis was conducted to identify statistical differences. The prevalence of full PTS...
Source: Medicine - May 1, 2019 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Ureaplasma parvum causes hyperammonemia presenting as refractory status epilepticus after kidney transplant
ConclusionUreaplasma infection must be suspected in cases of neurological symptoms associated with hyperammonemia without liver failure, following an organ transplant. Only urgent treatment could improve the prognosis and prevent severe neurological damage or death.
Source: Journal of Critical Care - February 6, 2020 Category: Gastroenterology Source Type: research