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Vaccination: Varicella-Zoster Virus Vaccine

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Total 265 results found since Jan 2013.

Reactivation of varicella zoster infection presenting as acute retinal necrosis post COVID 19 vaccination in an Asian Indian male
CONCLUSION AND SIGNIFICANCE: To the best of our knowledge this is the earliest description of a case that has a viral reactivation following COVID-19 vaccination. Elderly people with pre-existing comorbidities, may be at a risk of both primary coronavirus infection and unconceivable risk of aberrant immune reactions leading to a different virus infection or reactivation need to be kept in mind. We present a possible link between SARS-CoV-2 virus vaccination and varicella zoster reactivation in this patient.PMID:34541931 | DOI:10.1177/11206721211046485
Source: European Journal of Ophthalmology - September 20, 2021 Category: Opthalmology Authors: Sai Bhakti Mishra Padmamalini Mahendradas Ankush Kawali Srinivasan Sanjay Rohit Shetty Source Type: research

Locked-nucleotide antagonists to varicella zoster virus small non-coding RNA block viral growth and have potential as an anti-viral therapy
Antiviral Res. 2021 Jul 22:105144. doi: 10.1016/j.antiviral.2021.105144. Online ahead of print.ABSTRACTHerpes zoster (HZ) remains a significant health burden with millions of cases in North America and Europe annually. HZ is frequently followed by long-term pain or post-herpetic neuralgia (PHN). Although effective vaccines for HZ are available, currently used nucleotide analogues are often have limited effectiveness against HZ and especially PHN, so there remains a need for additional antiviral therapies for HZ. We recently identified a population of small non-coding RNA (sncRNA) encoded by Varicella Zoster Virus (VZV) and...
Source: Antiviral Research - July 25, 2021 Category: Virology Authors: Biswajit Das Punam Bisht Paul R Kinchington Ronald S Goldstein Source Type: research

A rare case of shingles after COVID-19 vaccine: is it a possible adverse effect?
Clin Exp Vaccine Res. 2021 May;10(2):198-201. doi: 10.7774/cevr.2021.10.2.198. Epub 2021 May 31.ABSTRACTCoronavirus disease 2019 (COVID-19) exhibit mild to moderate symptoms, whereas 15% of COVID-19 cases progress to pneumonia, some associated cutaneous findings are also reported as maculopapular eruptions, morbilliform rashes, urticaria, chickenpox-like lesions, and livedo reticularis. The inactivated COVID-19 vaccines are authorized for use in some countries including Turkey. Here, we report an unusual case of varicella-zoster virus (VZV) reactivation in a 68-year-old male patient who was vaccinated against COVID-19. The...
Source: Cell Research - July 5, 2021 Category: Cytology Authors: Saliha Bu şra Aksu G üzin Zeren Öztürk Source Type: research

Molecules, Vol. 26, Pages 1132: Advances and Perspectives in the Management of Varicella-Zoster Virus Infections
eck Varicella-zoster virus (VZV), a common and ubiquitous human-restricted pathogen, causes a primary infection (varicella or chickenpox) followed by establishment of latency in sensory ganglia. The virus can reactivate, causing herpes zoster (HZ, shingles) and leading to significant morbidity but rarely mortality, although in immunocompromised hosts, VZV can cause severe disseminated and occasionally fatal disease. We discuss VZV diseases and the decrease in their incidence due to the introduction of live-attenuated vaccines to prevent varicella or HZ. We also focus on acyclovir, valacyclovir, and famciclovir (FDA app...
Source: Molecules - February 20, 2021 Category: Chemistry Authors: Graciela Andrei Robert Snoeck Tags: Review Source Type: research

Shingles of the eye can cause lasting vision impairment
Shingles, or herpes zoster, is a viral infection known for its characteristic painful, burning, or itchy rash. This rash appears along a particular affected nerve, for example in a band on one side of the chest or abdomen that extends around to the back. In fact, the name shingles comes from cingulum, the Latin word for girdle, belt, or sash. Shingles is caused by reactivation of the varicella zoster virus, the virus that causes chickenpox. After the initial chickenpox infection resolves the virus lives on in nerves all over the body, but is kept in check by the immune system. The risk of shingles therefore increases with ...
Source: Harvard Health Blog - January 27, 2021 Category: Consumer Health News Authors: Miriam Barshak, MD Tags: Eye Health Healthy Aging Vaccines Source Type: blogs

Completion of the two-dose recombinant zoster vaccine series in adults 50 years and older.
CONCLUSION: Completion of RZV series appears suboptimal in the early phase of implementation. Despite similar accessibility in a health care system, completion varied by race/ethnicity, socioeconomic status, health status, and care seeking behavior, suggesting areas to target for improvement. PMID: 33441234 [PubMed - as supplied by publisher]
Source: Vaccine - January 11, 2021 Category: Allergy & Immunology Authors: Ackerson B, Qian L, Sy LS, Bruxvoort K, Wu J, Luo Y, Diaz-Decaro J, Talarico C, Tseng HF Tags: Vaccine Source Type: research

Shingles: What triggers this painful, burning rash?
If you’re like 95% of American adults, you had chickenpox as a kid. Before the United States started its widespread vaccination program in 1995, there were roughly four million cases of chickenpox every year. So, most people suffered through an infection with this highly contagious virus and its itchy, whole-body rash. But unlike many childhood viruses, the varicella-zoster virus that causes chickenpox doesn’t clear from the body when the illness ends. Instead it hangs around, taking up residence and lying dormant in the nerves, sometimes for decades, with the immune system holding it in check. In some people, it lives...
Source: Harvard Health Blog - December 14, 2020 Category: Consumer Health News Authors: Kelly Bilodeau Tags: Health Healthy Aging Skin and Hair Care Vaccines Source Type: blogs

Recombinant zoster vaccine (Shingrix ®): a new option for the prevention of herpes zoster and postherpetic neuralgia.
This article reviews the brief history, efficacy, and safety of the two vaccines and discusses the advantage of RZV over LZV based on the available literature. PMID: 32606264 [PubMed]
Source: Korean Journal of Pain - July 3, 2020 Category: Anesthesiology Tags: Korean J Pain Source Type: research

Fight Aging! Newsletter, May 25th 2020
In conclusion, our results suggest a previously unknown mechanism whereby the canonical NF-κB cascade and a mitochondrial fission pathway interdependently regulate endothelial inflammation. Lin28 as a Target for Nerve Regeneration https://www.fightaging.org/archives/2020/05/lin28-as-a-target-for-nerve-regeneration/ Researchers here show that the gene Lin28 regulates axon regrowth. In mice, raised levels of Lin28 produce greater regeneration of nerve injuries. Past research has investigated Lin28 from the standpoint of producing a more general improvement in regenerative capacity. It improves mitochondri...
Source: Fight Aging! - May 24, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Top 20 Research Studies of 2019 for Primary Care Physicians.
This article summarizes the clinical questions and bottom-line answers from the top 20 POEMs of 2019. Taking blood pressure medications at night results in a large mortality reduction over six years compared with morning dosing. Automated devices are the best way to measure blood pressure. Nonfasting lipid profiles are preferred over fasting lipid profiles, and nonfasting and fasting lipid profiles are equally effective at predicting risk. The benefit of statins for primary prevention in people 75 years and older is uncertain at best. Aspirin has no net benefit for primary prevention of cardiovascular disease and has no ef...
Source: American Family Physician - May 14, 2020 Category: Primary Care Authors: Ebell MH, Grad R Tags: Am Fam Physician Source Type: research

Postherpetic Neuralgia: Current Evidence on the Topical Film-Forming Spray with Bupivacaine Hydrochloride and a Review of Available Treatment Strategies
AbstractPurpose of ReviewThis is a comprehensive review of the literature about the use of bupivacaine hydrochloride for the treatment of post-herpetic neuralgia (PHN). It briefly reviews the background, biology, diagnosis and conventional treatment for PHN, and then introduces and compares the recent evidence for the use of topical bupivacaine.Recent FindingsPHN is defined by pain lasting 90  days or more after the initial presentation of herpes zoster (“Shingles”, HZ) rash and is the most common complication of this disease. A product of re-activation of the Varicella-Zoster virus (VZV), HZ is diagnosed more than 1 ...
Source: Advances in Therapy - April 14, 2020 Category: Drugs & Pharmacology Source Type: research