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Vaccination: Pneomococcal Vaccine

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Total 3041 results found since Jan 2013.

Cost-effectiveness analysis of pneumococcal conjugate vaccines in preventing pneumonia in Peruvian children
Conclusions: PCV10 and PCV13 are more cost effective than PCV7 in prevention of pneumonia in children <5 years-old in Peru. PCV13 prevents more hospitalizations and is more cost-effective than PCV10. These results should be considered when making decisions about the Peruvian National Inmunizations Schedule.
Source: The Journal of Infection in Developing Countries - December 15, 2014 Category: Infectious Diseases Source Type: research

Pneumococcal vaccination during pregnancy for preventing infant infection.
CONCLUSIONS: There is insufficient evidence to assess whether pneumococcal vaccination during pregnancy could reduce infant infections. PMID: 25613573 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - January 23, 2015 Category: Journals (General) Authors: Chaithongwongwatthana S, Yamasmit W, Limpongsanurak S, Lumbiganon P, Tolosa JE Tags: Cochrane Database Syst Rev Source Type: research

Zinc supplementation for the treatment of measles in children.
CONCLUSIONS: We cannot draw any definite conclusions from this review about the effects of zinc supplementation on clinical outcomes of children with measles due to the very low quality of the evidence available. There is insufficient evidence to confirm or refute the effect of zinc supplementation in measles. PMID: 25794053 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - March 20, 2015 Category: Journals (General) Authors: Awotiwon AA, Oduwole O, Sinha A, Okwundu CI Tags: Cochrane Database Syst Rev Source Type: research

Vitamin D and respiratory infections
This study aimed to review recent clinical and epidemiological studies conducted in adults and children, and to evaluate the functional role of vitamin D in respiratory infections. The evaluated studies show an important immunomodulatory role of vitamin D, which reduces the incidence and risk of URTIs, both in children and in adults. Combating URTIs can be done prophylactically, associating the use of vaccines against Streptococcus pneumoniae with strengthening the immune system through supplementation with vitamin D. These actions can significantly contribute to reducing the number of URTIs, the use of antibiotics, and co...
Source: The Journal of Infection in Developing Countries - April 15, 2015 Category: Infectious Diseases Source Type: research

Vaccines for Patients with COPD.
This article presents a brief overview of the different studies found, on the new patents, and the future strategies on the field. PMID: 25706527 [PubMed - in process]
Source: Recent Patents on Inflammation and Allergy Drug Discovery - June 4, 2015 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research

Knowledge gaps on paediatric respiratory infections in Morocco, Northern Africa
Conclusions Further efforts should be made towards the development of adequate surveillance programs to better clarify the epidemiology, etiology, antimicrobial susceptibility patterns and the effectiveness of the preventives and curatives strategies in place against paediatric ARIs in Morocco. Additionally, a holistical approach should be used to identify the heath determinants of ARIs among children.
Source: Archives of Public Health - June 15, 2015 Category: Global & Universal Source Type: research

Association between pneumococcal vaccination and cardiovascular outcomes: a systematic review and meta-analysis of cohort studies
Conclusion PV is associated with decreased risk of cardiovascular events and mortality. This protective effect increases at older age and in high cardiovascular risk subjects and decreases as the time elapses from PV. PV decreases the risk of MI and cerebrovascular events in the elderly.
Source: European Journal of Preventive Cardiology - August 10, 2015 Category: Cardiology Authors: Vlachopoulos, C. V., Terentes-Printzios, D. G., Aznaouridis, K. A., Pietri, P. G., Stefanadis, C. I. Tags: Original scientific paper Source Type: research

Reccurrent invasive pneumococcal disease in children host factors and vaccination response.
Authors: Ingels HA Abstract Streptococcus pneumoniae is still a leading cause of septicaemia, pneumonia and meningitis in young children world-wide with over half a million children dying annually from pneumococcal disease.  Some children are prone to repeated episodes of invasive pneumococcal disease (IPD) because of an underlying predisposing disease. Recurrent IPD (rIPD) is a rarity and published reports on rIPD are limited by having few children included, selected groups of patients or short follow-up periods. Deficiencies in the innate or adaptive immune system have been described in children with rIPD, but t...
Source: Danish Medical Journal - December 12, 2015 Category: Journals (General) Tags: Dan Med J Source Type: research

Global Burden of Neonatal Invasive Pneumococcal Disease: A Systematic Review and Meta-analysis
Conclusions: Pneumococcus was a recognized pathogen among neonates in all development regions of the world. The burden of neonatal IPD, particularly in the least-developed UN country stratum, requires substantial further evaluation.
Source: The Pediatric Infectious Disease Journal - January 12, 2016 Category: Infectious Diseases Tags: Original Studies Source Type: research

Methods and challenges for the health impact assessment of vaccination programs in Latin America
CONCLUSIONS Over the last years, a significant number of health impact assessments of pneumococcal and rotavirus vaccination programs have been conducted in Latin America and the Caribbean. These studies were carried out few years after the programs were implemented, meet the basic methodological requirements and suggest positive health impact. Future assessments should consider methodological issues and challenges arisen in these first studies conducted in the region. RESUMO OBJETIVO Descrever métodos e desafios enfrentados na avaliação do impacto de programas de vacinação, com foco nas vacinas pneumocócica conjugad...
Source: Revista de Saude Publica - January 15, 2016 Category: Global & Universal Source Type: research

Streptococcus pneumoniae fructose-1,6-bisphosphate aldolase, a protein vaccine candidate, elicits Th1/Th2/Th17-type cytokine responses in mice.
Abstract Streptococcus pneumoniae (S. pneumoniae) is a major pathogen worldwide. The currently available polysaccharide-based vaccines significantly reduce morbidity and mortality. However, the inherent disadvantages of the currently available polysaccharide-based vaccines have motivated the search for other bacterial immunogens capable of eliciting a protective immune response against S. pneumoniae. Fructose-1,6-bisphosphate aldolase (FBA) is a glycolytic enzyme, which was found to localize to the bacterial surface, where it functions as an adhesin. Previously, immunizing mice with recombinant FBA (rFBA) in...
Source: International Journal of Molecular Medicine - March 1, 2016 Category: Molecular Biology Authors: Elhaik Goldman S, Dotan S, Talias A, Lilo A, Azriel S, Malka I, Portnoi M, Ohayon A, Kafka D, Ellis R, Elkabets M, Porgador A, Levin D, Azhari R, Swiatlo E, Ling E, Feldman G, Tal M, Dagan R, Mizrachi Nebenzahl Y Tags: Int J Mol Med Source Type: research

Injection Site Lichenoid Dermatitis Following Pneumococcal Vaccination: Report and Review of Cutaneous Conditions Occurring at Vaccination Sites
Conclusions Dermatoses at the injection sites of vaccines can be granulomatous, immunity-related conditions, infections, lichenoid, neutrophilic, or pseudolymphomatous. Basal cell carcinoma and squamous cell carcinoma are the most common vaccination site-associated malignancies; however, melanoma and sarcomas (dermatofibrosarcoma protuberans, fibrosarcoma, and malignant fibrous histiocytoma) are also smallpox vaccine-related site neoplasms. A cutaneous immunocompromised district that is created by vaccine-induced local immunologic changes is hypothesized to be the pathogenesis of vaccination site reactions.
Source: Dermatology and Therapy - March 16, 2016 Category: Dermatology Source Type: research

Influenza vaccination for healthcare workers who care for people aged 60 or older living in long-term care institutions.
CONCLUSIONS: Our review findings have not identified conclusive evidence of benefit of HCW vaccination programmes on specific outcomes of laboratory-proven influenza, its complications (lower respiratory tract infection, hospitalisation or death due to lower respiratory tract illness), or all cause mortality in people over the age of 60 who live in care institutions. This review did not find information on co-interventions with healthcare worker vaccination: hand-washing, face masks, early detection of laboratory-proven influenza, quarantine, avoiding admissions, antivirals and asking healthcare workers with influenza or i...
Source: Cochrane Database of Systematic Reviews - June 1, 2016 Category: Journals (General) Authors: Thomas RE, Jefferson T, Lasserson TJ Tags: Cochrane Database Syst Rev Source Type: research