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Vaccination: Pneomococcal Vaccine
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B Cell Reconstitution and Influencing Factors After Hematopoietic Stem Cell Transplantation in Children
Nicolaas G. van der Maas, Dagmar Berghuis, Mirjam van der Burg and Arjan C. Lankester*
Willem-Alexander Children's Hospital, Department of Pediatrics and Laboratory for Pediatric Immunology, Leiden University Medical Center, Leiden, Netherlands
B cell reconstitution after hematopoietic stem cell transplantation (HSCT) is variable and influenced by different patient, donor, and treatment related factors. In this review we describe B cell reconstitution after pediatric allogeneic HST, including the kinetics of reconstitution of the different B cell subsets and the development of the B cell repertoire, and d...
Source: Frontiers in Immunology - April 11, 2019 Category: Allergy & Immunology Source Type: research
The impact of traditional plants and their secondary metabolites in the discovery of COVID-19 treatment.
CONCLUSION: The present review has listed plants that have presented antiviral potential in the previous coronavirus pandemics and their secondary metabolites which could be significant for the development of novel and a safer drug which could prevent and cure coronavirus infection worldwide.
PMID: 33213320 [PubMed - as supplied by publisher]
Source: Current Pharmaceutical Design - November 17, 2020 Category: Drugs & Pharmacology Authors: Bibi S, Sarfraz A, Mustafa G, Ahmed Z, Zeb MA, Wang YB, Khan T, Khan MS, Kamal MA, Yu H Tags: Curr Pharm Des Source Type: research
Clinical features and mechanistic insights into drug repurposing for combating COVID-19
Int J Biochem Cell Biol. 2021 Nov 5:106114. doi: 10.1016/j.biocel.2021.106114. Online ahead of print.ABSTRACTSevere acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged from Wuhan in China before it spread to the entire globe. It causes coronavirus disease of 2019 (COVID-19) where mostly individuals present mild symptoms, some remain asymptomatic and some show severe lung inflammation and pneumonia in the host through the induction of a marked inflammatory 'cytokine storm'. New and efficacious vaccines have been developed and put into clinical practice in record time, however, there is a still a need for effective...
Source: The International Journal of Biochemistry and Cell Biology - November 8, 2021 Category: Biochemistry Authors: Purva Asrani Keshav Tiwari Mathew Suji Eapen Kielan Darcy McAlinden Greg Haug Matt D Johansen Philip M Hansbro Katie L Flanagan Md Imtaiyaz Hassan Sukhwinder Singh Sohal Source Type: research
Educational interventions for health professionals managing chronic obstructive pulmonary disease in primary care
CONCLUSIONS: The evidence of efficacy was equivocal for educational interventions for health professionals in primary care on the proportion of COPD diagnoses confirmed with spirometry, the proportion of patients with COPD who participate in pulmonary rehabilitation, and the proportion of patients prescribed guideline-recommended COPD respiratory medications. Educational interventions for health professionals may improve influenza vaccination rates among patients with COPD and patient satisfaction with care. The quality of evidence for most outcomes was low or very low due to heterogeneity and methodological limitations of...
Source: Cochrane Database of Systematic Reviews - May 6, 2022 Category: General Medicine Authors: Amanda J Cross Dennis Thomas Jenifer Liang Michael J Abramson Johnson George Elida Zairina Source Type: research
Varicella-Zoster virus reactivation following severe acute respiratory syndrome coronavirus 2 vaccination or infection: New insights
CONCLUSION: This study indicates that the occurrence of VZV reactivation is clinically relevant. However, our findings suggest that COVID-19 vaccination is safe, and remains strongly recommended.PMID:35931613 | PMC:PMC9340059 | DOI:10.1016/j.ejim.2022.07.022
Source: European Journal of Internal Medicine - August 5, 2022 Category: Internal Medicine Authors: Raquel Martinez-Reviejo Sofia Tejada Ganiyat A R Adebanjo Camilla Chello Miriam C Machado Francesca R Parisella Magda Campins Antonella Tammaro Jordi Rello Source Type: research
The COVID-19 pandemic and vaccination abandonment in children: spatial heterogeneity maps
CONCLUSION: in an attempt to mitigate the devastating impact of the COVID-19 pandemic, the immunization program experienced setbacks. The presence of clusters points to the need to implement integrated strategies that may involve different sectors for an active search for children and prevent outbreaks of vaccine-preventable diseases in the near future.PMID:36228235 | PMC:PMC9545939 | DOI:10.1590/1518-8345.6132.3642
Source: Revista Latino-Americana de Enfermagem - October 13, 2022 Category: Nursing Authors: Rayssa Nogueira Rodrigues Gabriela Louren ça Martins do Nascimento Luiz Henrique Arroyo Ricardo Alexandre Arc êncio Val éria Conceição de Oliveira Eliete Albano de Azevedo Guimar ães Source Type: research
Exclusion of older adults and immunocompromised individuals in influenza, pneumococcal and COVID-19 vaccine trials before and after the COVID-19 pandemic
CONCLUSIONS: During the COVID-19 pandemic, we found a decrease in the exclusion of older adults from vaccine trials but no significant change in the inclusion of immunocompromised individulas.PMID:37027085 | PMC:PMC10080508 | DOI:10.1007/s40520-023-02380-4
Source: Aging Clinical and Experimental Research - April 7, 2023 Category: Geriatrics Authors: Katrine Bukan Toby Pearce-Slade Mads Eiberg Marco Tinelli Dafna Yahav Jose Tuells Olivier Epaulard Jon G Holler Casper Roed Christian S øborg Jens-Ulrik St æhr Jensen Zitta Barrella Harboe Source Type: research
