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Vaccination: Meningitis Vaccine

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Total 2891 results found since Jan 2013.

Acute otitis media and antibiotics - a systematic review.
CONCLUSIONS: ABX appears to have a limited effect on both primary and secondary outcomes compared with placebo. A substantial number of patients experienced AE. New RCTs are needed to further clarify the effect. Ideally, RCTs could be conducted in Danish general practices in collaboration with practicing ear, nose and throat specialists to obtain large unselected populations with high rates of vaccine coverage. Until more evidence is provided, ABX should be considered among children younger than two years of age with severe symptoms of AOM, i.e. fewer and affected well-being. PMID: 33215607 [PubMed - in process]
Source: Danish Medical Journal - November 21, 2020 Category: General Medicine Tags: Dan Med J Source Type: research

Pneumococcal conjugate vaccines for preventing acute otitis media in children.
CONCLUSIONS: Administration of the licenced CRM197-PCV7 and PHiD-CV10 during early infancy is associated with large relative risk reductions in pneumococcal AOM. However, the effects of these vaccines on all-cause AOM is far more uncertain based on low- to moderate-certainty evidence. We found no evidence of a beneficial effect on all-cause AOM of administering PCVs in high-risk infants, after early infancy, and in older children with a history of respiratory illness. Compared to control vaccines, PCVs were associated with an increase in mild local reactions (redness, swelling), fever, and pain and/or tenderness. There was...
Source: Cochrane Database of Systematic Reviews - November 24, 2020 Category: General Medicine Authors: de Sévaux JL, Venekamp RP, Lutje V, Hak E, Schilder AG, Sanders EA, Damoiseaux RA Tags: Cochrane Database Syst Rev Source Type: research

IJERPH, Vol. 17, Pages 9146: Shared Decision Making Enhances Pneumococcal Vaccination Rates in Adult Patients in Outpatient Care
The objective of this review was to assess the impact of SDM on pneumococcal vaccination rates in adult patients. We conducted a systematic literature search in MEDLINE, EMBASE, CENTRAL, PsycINFO, and ERIC. RCTs and cluster RCTs were included, if they aimed to enhance pneumococcal vaccination rates in adult patients and comprised a personal interaction between health care provider (HCP) and patient. Three further aspects of the SDM process (patient activation, bi-directional exchange of information and bi-directional deliberation) were assessed. A meta-analysis was conducted for the effects of interventions on vaccination ...
Source: International Journal of Environmental Research and Public Health - December 7, 2020 Category: Environmental Health Authors: Kuehne Sanftenberg Dreischulte Gensichen Tags: Review Source Type: research

Google search behavior for meningitis and its vaccines: an infodemiological study
The internet has made significant contributions towards health education. Analyzing the pattern of online behavior regarding meningitis and vaccinations may be worthwhile. It is hypothesized that the online se...
Source: BMC Neurology - June 23, 2021 Category: Neurology Authors: John Angelo Luigi S. Perez, Adrian I. Espiritu and Roland Dominic G. Jamora Tags: Research Source Type: research

Invasive Pneumococcal Disease burden and PCV coverage in children under five in Southeast Asia: implications for India
Conclusions: Widespread PCV use could successfully reduce IPD burden in the region due to high serotype coverage by available PCVs; emphasis should be placed on increasing vaccination uptake, for every child, particularly in India. Reducing health system barriers and improving surveillance and awareness is essential to improve coverage and effectively prevent IPD morbidity and mortality particularly in at risk regions.
Source: The Journal of Infection in Developing Countries - June 29, 2021 Category: Infectious Diseases Source Type: research

Properly Naming the Sinusitis-Otitis-Conjunctivitis Syndrome
One of our nonphysician providers recently announced, “This kid has that double-sickening thing you talk about all the time." She was referring to the sudden worsening of signs and symptoms (e.g., onset of fever) in a patient who had had an upper respiratory tract infection for several days.The majority of links in a Google search for “double-sickening" are references for sinusitis, but new-onset pneumonia is another double-sickening event. The Infectious Diseases Society of America guidelines for sinusitis acknowledge double-sickening and concur that pneumonia can present similarly. I investigate for sinusit...
Source: M2E Too! Mellick's Multimedia EduBlog - November 1, 2021 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Prevalence of Bacteremia in Febrile Patients With Sickle Cell Disease: Meta-Analysis of Observational Studies
Conclusions There appears to be a need to develop a risk stratification strategy to guide physicians to manage febrile patients with SCD based on factors including, but not limited to, history and clinical examination, vaccination status, use of prophylactic antibiotics, laboratory values, likely source of infection, and accessibility to health care.
Source: Pediatric Emergency Care - December 1, 2021 Category: Emergency Medicine Tags: Review Articles Source Type: research

Health actor approaches to financing universal coverage strategies for pneumococcal and rotavirus immunisation programmes in low-income and middle-income countries: a scoping review protocol
This study protocol outline a scoping review of the peer-reviewed and the grey literature, using established methodological framework for scoping review. Literature will be identified through a comprehensive search of multiple databases and grey literature. All peer-reviewed implementation research studies from the year 2002 addressing financing and universal coverage of immunisation programmes for the pneumococcal conjugated vaccine and rotavirus vaccines immunisation interventions will be included and grey literature published in/after the year 2015. For the study scope, population, concept and context are defined: Popul...
Source: BMJ Open - December 14, 2021 Category: General Medicine Authors: Ogundele, O. J., Fadel, S., Braitstein, P., Di Ruggiero, E. Tags: Open access, Global health Source Type: research

Meningococcal Vaccination and Risk of Serious Adverse Events: A Systematic Review
Conclusions Vaccination is adequate protection against meningococcal infections, with reported minimal adverse effects after immunization that do not constitute absolute contraindications to vaccination except allergic or anaphylactic reaction that needs further evaluation.
Source: Infectious Diseases in Clinical Practice - March 1, 2022 Category: Infectious Diseases Tags: Original Articles Source Type: research

Therapeutic Potential of Tralokinumab in the Treatment of Atopic Dermatitis: A Review on the Emerging Clinical Data
Clin Cosmet Investig Dermatol. 2022 Jun 3;15:1037-1043. doi: 10.2147/CCID.S267217. eCollection 2022.ABSTRACTAtopic dermatitis (AD) is a chronic inflammatory skin disease that greatly impacts patient quality of life. Type 2 cytokine interleukin (IL)-13 is integral to the pathogenesis of AD. Tralokinumab is a fully human IgG4 monoclonal antibody that specifically targets IL-13, preventing downstream signaling of inflammatory pathways that may contribute to AD. Tralokinumab was US Food and Drug administration (FDA) recently approved for the treatment of moderate to severe AD on December 28, 2021. In our review, we will explor...
Source: Clinical, Cosmetic and Investigational Dermatology - June 10, 2022 Category: Dermatology Authors: Katherine A Kelly Patrick O Perche Steven R Feldman Source Type: research

News Fatigue, Anti-Vax and Wars
Nothing is so firmly believed as what is least known.                                                     Michel de MontaigneBy Jan LundiusSTOCKHOLM, Jul 13 2022 (IPS) During the beginning of the pandemic, people wanted to learn more about COVID-19. Enclosed in their homes they watched with fear and fascination how the pandemic swept over the world, while comparing ...
Source: IPS Inter Press Service - Health - July 13, 2022 Category: International Medicine & Public Health Authors: Jan Lundius Tags: Armed Conflicts COVID-19 Global Headlines Health Humanitarian Emergencies TerraViva United Nations IPS UN Bureau Source Type: news