Filtered By:
Procedure: Perfusion
This page shows you your search results in order of date.
Order by Relevance | Date
Total 26728 results found since Jan 2013.
Does heparin rebound lead to postoperative blood loss in patients undergoing cardiac surgery with cardiopulmonary bypass?
CONCLUSION: The influence of heparin rebound on postoperative bleeding seems to be negligible, but might get significant in conjunction with incomplete heparin reversal or other coagulopathies. For that reason, it might be useful to get a picture of the entire coagulation spectrum after cardiac surgery, as can be done by the use of a viscoelastic test in conjunction with an aggregometry test.PMID:37734336 | DOI:10.1177/02676591231199218
Source: Perfusion - September 21, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Marije Rijpkema Eline A Vlot Marco C Stehouwer Peter Bruins Source Type: research
Role of toll-like receptor-mediated pyroptosis in sepsis-induced cardiomyopathy
Biomed Pharmacother. 2023 Sep 19;167:115493. doi: 10.1016/j.biopha.2023.115493. Online ahead of print.ABSTRACTSepsis, a life-threatening dysregulated status of the host response to infection, can cause multiorgan dysfunction and mortality. Sepsis places a heavy burden on the cardiovascular system due to the pathological imbalance of hyperinflammation and immune suppression. Myocardial injury and cardiac dysfunction caused by the aberrant host responses to pathogens can lead to cardiomyopathy, one of the most critical complications of sepsis. However, many questions about the specific mechanisms and characteristics of this ...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 21, 2023 Category: Drugs & Pharmacology Authors: Yixuan Fan Baoyi Guan Jianxing Xu He Zhang Liang Yi Zhixu Yang Source Type: research
Multiscale Structure and Function of the Aortic Valve Apparatus
Physiol Rev. 2023 Sep 21. doi: 10.1152/physrev.00038.2022. Online ahead of print.ABSTRACTWhile studying the aortic valve in isolation has facilitated the development of life-saving procedures and technologies, the dynamic interplay of the aortic valve and its surrounding structures is vital to preserving their function across the wide range of conditions encountered in an active lifestyle. Our view is that these structures should be viewed as an integrated functional unit, herein referred to as the aortic valve apparatus (AVA). The coupling of the aortic valve and root, left ventricular outflow tract, and blood circulation...
Source: Physiological Reviews - September 21, 2023 Category: Physiology Authors: Hussam El-Nashar Malak Sabry Yuan-Tsan Tseng Nadine Francis Najma Latif Kim H Parker James E Moore Magdi H Yacoub Source Type: research
Microvascular dysfunction in women with a history of hypertensive disorders of pregnancy: A population-based retrospective cohort study
CONCLUSIONS: The findings reveal microvascular dysfunction at long-term follow up in women with previous pre-eclampsia and strengthen the possible role of endothelial dysfunction as a link to the increased risk of cardiovascular disease in women with HDP.PMID:37732494 | DOI:10.1111/1471-0528.17665
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 21, 2023 Category: OBGYN Authors: Stina Bj örkman Caroline Lilliecreutz Marie Bladh Tomas Str ömberg Carl Johan Östgren Arina Mahmoud Arian Kafashian Sara Bergstrand Sofia Sederholm Lawesson Source Type: research
Protocolised early de-resuscitation in septic shock (REDUCE): protocol for a randomised controlled multicentre feasibility trial
Background
Fluid overload is associated with excess mortality in septic shock. Current approaches to reduce fluid overload include restrictive administration of fluid or active removal of accumulated fluid. However, evidence on active fluid removal is scarce. The aim of this study is to assess the efficacy and feasibility of an early de-resuscitation protocol in patients with septic shock.
Methods
All patients admitted to the intensive care unit (ICU) with a septic shock are screened, and eligible patients will be randomised in a 1:1 ratio to intervention or standard of care. Intervention: Fluid management will be perform...
Source: BMJ Open - September 21, 2023 Category: General Medicine Authors: Messmer, A., Pietsch, U., Siegemund, M., Buehler, P., Waskowski, J., Müller, M., Uehlinger, D. E., Hollinger, A., Filipovic, M., Berger, D., Schefold, J. C., Pfortmueller, C. A. Tags: Open access, Intensive care Source Type: research
Dapagliflozin promotes angiogenesis in hindlimb ischemia mice by inducing M2 macrophage polarization
Critical limb ischemia (CLI) is associated with a higher risk of limb amputation and cardiovascular death. Dapagliflozin has shown great potential in the treatment of cardiovascular disease. However, the effects of dapagliflozin on CLI and the underlying mechanisms have not been fully elucidated. We evaluated the effect of dapagliflozin on recovery from limb ischemia using a mouse model of hindlimb ischemia. The flow of perfusion was evaluated using a laser Doppler system. Tissue response was assessed by analyzing capillary density, arterial density, and the degree of fibrosis in the gastrocnemius muscle. Immunofluorescenc...
Source: Frontiers in Pharmacology - September 21, 2023 Category: Drugs & Pharmacology Source Type: research
Cost-effectiveness of terlipressin for hepatorenal syndrome: The United States hospital perspective
CONCLUSIONS: HRS patients treated with terlipressin experienced better clinical outcomes and a lower cost per treatment response vs alternative treatments. ICU days and pharmacy costs were key cost drivers distinguishing the treatment groups. These outcomes suggest that terlipressin is cost-effective on the basis of total cost per response achieved.PMID:37729445 | DOI:10.1080/13696998.2023.2260693
Source: Journal of Medical Economics - September 20, 2023 Category: Health Management Authors: John A Carter Xingyue Huang Khurram Jamil Shelby Corman Varun Ektare John Niewoehner Source Type: research
Can Open Distal Repair Be Safely Used in All Patients with Type A Acute Aortic Dissection?
CONCLUSION: We conclude that the open repair can be used in most if not all cases of surgical repair of type A acute aortic dissection.PMID:37730310 | DOI:10.5761/atcs.oa.23-00086
Source: Annals of Thoracic and Cardiovascular Surgery - September 20, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Georgi Manchev Vassil Gegouskov Vladimir Kornovski Georgi Yankov Valya Goranovska Vicktoria Ilieva Vicktoria Petrova Source Type: research
Cost-effectiveness of terlipressin for hepatorenal syndrome: The United States hospital perspective
CONCLUSIONS: HRS patients treated with terlipressin experienced better clinical outcomes and a lower cost per treatment response vs alternative treatments. ICU days and pharmacy costs were key cost drivers distinguishing the treatment groups. These outcomes suggest that terlipressin is cost-effective on the basis of total cost per response achieved.PMID:37729445 | DOI:10.1080/13696998.2023.2260693
Source: Journal of Medical Economics - September 20, 2023 Category: Health Management Authors: John A Carter Xingyue Huang Khurram Jamil Shelby Corman Varun Ektare John Niewoehner Source Type: research
Hyperpolarized 1- < sup > 13 < /sup > Cpyruvate Magnetic Resonance Spectroscopy Shows That Agmatine Increased Lactate Production in the Brain of Type 2 Diabetic Mice
CONCLUSION: Agmatine influences the NADH/NAD+ redox state in the brains of T2DM mice, which may be connected with enhanced cognitive performance and increased conversion of HP [1-13C]pyruvate to HP [1-13C]lactate.PMID:37727922 | DOI:10.3349/ymj.2022.0554
Source: Yonsei Medical Journal - September 20, 2023 Category: Universities & Medical Training Authors: Young-Suk Choi Jae Eun Song Eosu Kim Chul Hoon Kim Jong Eun Lee Ho-Taek Song Source Type: research
Can Open Distal Repair Be Safely Used in All Patients with Type A Acute Aortic Dissection?
CONCLUSION: We conclude that the open repair can be used in most if not all cases of surgical repair of type A acute aortic dissection.PMID:37730310 | DOI:10.5761/atcs.oa.23-00086
Source: Annals of Thoracic and Cardiovascular Surgery - September 20, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Georgi Manchev Vassil Gegouskov Vladimir Kornovski Georgi Yankov Valya Goranovska Vicktoria Ilieva Vicktoria Petrova Source Type: research
Assessment of systemic circulation using ultrasound Doppler in late onset neonatal sepsis and its clinical correlation: an observational study
ConclusionLONS is associated with alterations in cerebral, splanchnic, and renal perfusion seen as abnormal blood flow velocimetry and vascular resistance which may predispose to IVH, NEC, and AKI.
Source: Journal of Ultrasound - September 20, 2023 Category: Radiology Source Type: research
Spinal cord perfusion pressure correlates with breathing function in patients with acute, cervical traumatic spinal cord injuries: an observational study
This study aims to determine the relationship between spinal cord perfusion pressure (SCPP) and breathing function in patients with acute cervical traumatic spinal cord injuries.
Source: Critical Care - September 20, 2023 Category: Intensive Care Authors: Ravindran Visagan, Ellaine Boseta, Argyro Zoumprouli, Marios C. Papadopoulos and Samira Saadoun Tags: Research Source Type: research
Three-dimensional electrical impedance tomography (EIT) to study regional ventilation/perfusion (V/Q ̇) ratios in anesthetized pigs
This study aimed to develop a 3D method for assessing ventilation/perfusion (V/Q̇) ratios in a pig model of hemodynamic perturbations using electrical impedance tomography (EIT). In order to evaluate the physiological coherence of changes in EIT-derived V/Q̇ ratios, global EIT-derived V/Q̇ mismatches were compared with global gold-standards. The study found regional heterogeneity in the distribution of V/Q̇ ratios in both the ventrodorsal and craniocaudal directions. Although global EIT-derived indices of V/Q̇ mismatch consistently underestimated both low and high V/Q̇ mismatch compared to global gold standards, the ...
Source: American Journal of Physiology. Lung Cellular and Molecular Physiology - September 19, 2023 Category: Cytology Authors: Shannon Larrabee Sarah Nugen Alejandro Bruhn Ian Porter Symon Stowe Andy Adler Manuel Martin-Flores Joaquin Araos Source Type: research
