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Folk medicine for the treatment of eye diseases in dalmatia in the 19th century
Acta Med Hist Adriat. 2023 Jul 18;21(1):171-184. doi: 10.31952/amha.21.1.8.ABSTRACTFolk medicine is a traditional medical practice in the general population, especially in rural areas. Traditional medicine methods used herbal remedies as well as human and animal substances and minerals. The most commonly used drugs in the treatment of eye diseases were drugs of plant origin like chamomile, eyebright and greater celandine, then drugs of human and animal origin like breast milk, saliva, honey, animal bile, and copper sulfate from mineral origin. There is little information in the literature discussing the folk treatment of o...
Source: Medical History - September 5, 2023 Category: History of Medicine Authors: Milan Ivani šević Source Type: research

Folk medicine for the treatment of eye diseases in dalmatia in the 19th century
Acta Med Hist Adriat. 2023 Jul 18;21(1):171-184. doi: 10.31952/amha.21.1.8.ABSTRACTFolk medicine is a traditional medical practice in the general population, especially in rural areas. Traditional medicine methods used herbal remedies as well as human and animal substances and minerals. The most commonly used drugs in the treatment of eye diseases were drugs of plant origin like chamomile, eyebright and greater celandine, then drugs of human and animal origin like breast milk, saliva, honey, animal bile, and copper sulfate from mineral origin. There is little information in the literature discussing the folk treatment of o...
Source: Medical History - September 5, 2023 Category: History of Medicine Authors: Milan Ivani šević Source Type: research

A new biphenanthrene with cytotoxic activity from < em > Liparis nervosa < /em > (Thunb.) Lindl
Nat Prod Res. 2023 Sep 3:1-7. doi: 10.1080/14786419.2023.2233670. Online ahead of print.ABSTRACT2,7,2'-Trihydroxy-3,4,4'7'-tetramethoxy-1,1'-biphenanthrene (1), a previously undescribed biphenanthrene, and five known phenanthrenes, i.e. 2,5-dihydroxy-4-methoxy-9,10-dihydroxyphenanthrene (2), 2,4-dihydroxy -7-methoxy-9,10-dihydroxyphenanthrene (3), 7-hydroxy-2-methoxy-phenanthrene-1,4-dione (4), 7-hydroxy-2-methoxy-9,10-dihydro-phenanthrene-1,4-dione (5), and 4,4',7,7'-tetrahydroxy-2,2'-dimethoxy-9,9',10,10'-tetrahydro-1,1'-biphenanthrene (6) were isolated from the whole plant (stems, leaves, roots and fruits) of Liparis ne...
Source: Natural Product Research - September 4, 2023 Category: Biochemistry Authors: Liang Liu Qi-Meng Yin Qi-Jun Dai Xuan-Yuan Chen Xi-Qing Chen Jian-Bin Wang Han-Qing Pang Xian-Wen Zhang Source Type: research

Aloperine Protects Pulmonary Hypertension via Triggering PPAR γ Signaling and Inhibiting Calcium Regulatory Pathway in Pulmonary Arterial Smooth Muscle Cells
In this study, monocrotaline-induced PH (MCT-PH) rat model and primarily cultured rat distal pulmonary arterial smooth muscle cells (PASMCs) were used to investigate the mechanisms of ALO on experimental PH, pulmonary vascular remodeling and excessive proliferation of PASMCs. Results showed that: Firstly, ALO significantly prevented the disease development of MCT-PH by inhibiting right ventricular systolic pressure (RVSP) and right ventricular hypertrophy indexed by Fulton Index, normalizing the pulmonary arterials (PAs) remodeling and improving the right ventricular function indexed by transthoracic echocardiography. ALO ...
Source: Am J Physiol Cell Ph... - September 4, 2023 Category: Cytology Authors: Xiaoqian Shan Jing Wang Huazhuo Feng Zizhou Zhang Qiuyu Zheng Qing Zhang Kai Yang Jian Wang Lei Xu Source Type: research

Effects of methomyl on the intestinal microbiome and hepatic transcriptome of tilapia, and the modifying effects of mint co-culture
In this study, we investigated the impact of MET on the antioxidant system of Oreochromis niloticus in presence of mint as a floating bed. Results revealed that the superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase, and glutathione S-transferase significantly decreased and the GSH content significantly increased in the intestine. The hepatic peroxisome proliferator-activated receptor (PPAR) signalling pathway, carbon metabolism, renal phosphoinositide 3-kinase (PI3K)-Akt, mitogen-activated protein kinase (MAPK) signalling pathway, and phagosomes were significantly affected. Upon long-term exposure, circadi...
Source: Aquatic Toxicology - September 4, 2023 Category: Toxicology Authors: Yao Zheng Benkhelifa Fateh Gangchun Xu Source Type: research

Genotype-Controlled Vertical Transmission Exerts Selective Pressure on Community Assembly of Salvia miltiorrhiza
Microb Ecol. 2023 Sep 4. doi: 10.1007/s00248-023-02295-7. Online ahead of print.ABSTRACTThe plant's endophytic fungi play an important role in promoting host development and metabolism. Studies have shown that the factors affecting the assembly of the endophyte community mainly include host genotype, vertical transmission, and soil origin. However, we do not know the role of vertically transmitted endohytic fungi influences on the host-plant's endophytic community assembly. Salvia miltiorrhiza from three production areas were used as research objects; we constructed three production area genotypes of S. miltiorrhiza regene...
Source: Microbial Ecology - September 4, 2023 Category: Microbiology Authors: Hongyang Lv Xiaoyu Li Dongmei He Xin Chen Min Liu Yin Lan Jin Zhao Hai Wang Zhuyun Yan Source Type: research

Aloperine Protects Pulmonary Hypertension via Triggering PPAR γ Signaling and Inhibiting Calcium Regulatory Pathway in Pulmonary Arterial Smooth Muscle Cells
In this study, monocrotaline-induced PH (MCT-PH) rat model and primarily cultured rat distal pulmonary arterial smooth muscle cells (PASMCs) were used to investigate the mechanisms of ALO on experimental PH, pulmonary vascular remodeling and excessive proliferation of PASMCs. Results showed that: Firstly, ALO significantly prevented the disease development of MCT-PH by inhibiting right ventricular systolic pressure (RVSP) and right ventricular hypertrophy indexed by Fulton Index, normalizing the pulmonary arterials (PAs) remodeling and improving the right ventricular function indexed by transthoracic echocardiography. ALO ...
Source: Am J Physiol Cell Ph... - September 4, 2023 Category: Cytology Authors: Xiaoqian Shan Jing Wang Huazhuo Feng Zizhou Zhang Qiuyu Zheng Qing Zhang Kai Yang Jian Wang Lei Xu Source Type: research

Genotype-Controlled Vertical Transmission Exerts Selective Pressure on Community Assembly of Salvia miltiorrhiza
Microb Ecol. 2023 Sep 4. doi: 10.1007/s00248-023-02295-7. Online ahead of print.ABSTRACTThe plant's endophytic fungi play an important role in promoting host development and metabolism. Studies have shown that the factors affecting the assembly of the endophyte community mainly include host genotype, vertical transmission, and soil origin. However, we do not know the role of vertically transmitted endohytic fungi influences on the host-plant's endophytic community assembly. Salvia miltiorrhiza from three production areas were used as research objects; we constructed three production area genotypes of S. miltiorrhiza regene...
Source: Microbial Ecology - September 4, 2023 Category: Microbiology Authors: Hongyang Lv Xiaoyu Li Dongmei He Xin Chen Min Liu Yin Lan Jin Zhao Hai Wang Zhuyun Yan Source Type: research

A new biphenanthrene with cytotoxic activity from < em > Liparis nervosa < /em > (Thunb.) Lindl
Nat Prod Res. 2023 Sep 3:1-7. doi: 10.1080/14786419.2023.2233670. Online ahead of print.ABSTRACT2,7,2'-Trihydroxy-3,4,4'7'-tetramethoxy-1,1'-biphenanthrene (1), a previously undescribed biphenanthrene, and five known phenanthrenes, i.e. 2,5-dihydroxy-4-methoxy-9,10-dihydroxyphenanthrene (2), 2,4-dihydroxy -7-methoxy-9,10-dihydroxyphenanthrene (3), 7-hydroxy-2-methoxy-phenanthrene-1,4-dione (4), 7-hydroxy-2-methoxy-9,10-dihydro-phenanthrene-1,4-dione (5), and 4,4',7,7'-tetrahydroxy-2,2'-dimethoxy-9,9',10,10'-tetrahydro-1,1'-biphenanthrene (6) were isolated from the whole plant (stems, leaves, roots and fruits) of Liparis ne...
Source: Natural Product Research - September 4, 2023 Category: Biochemistry Authors: Liang Liu Qi-Meng Yin Qi-Jun Dai Xuan-Yuan Chen Xi-Qing Chen Jian-Bin Wang Han-Qing Pang Xian-Wen Zhang Source Type: research

Efficacy and Tolerability Evaluation of a Nutraceutical Composition Containing Vitex agnus-castus Extract (EVX40 ™), Pyridoxine, and Magnesium in Premenstrual Syndrome: A Real-World, Interventional, Comparative Study
Conclusion The results of the current study conclude that the nutraceutical composition of Vitex agnus-castus extract, vitamin B6, and magnesium is effective in reducing the severity of PMS symptoms and improving the quality of life of PMS subjects. The nutraceutical therapy provided greater relief from PMS symptoms compared to standard therapy alone, and this effect was augmented when the nutraceutical therapy was provided in combination with standard therapies. Similarly, the improvement in quality-of-life parameters was greater in subjects treated with nutraceuticals alone or in combination therapy. Despite the limitati...
Source: Pain Physician - September 4, 2023 Category: Anesthesiology Authors: Varun P Sureja Dharmeshkumar B Kheni Vishal P Dubey Jignesh Kansagra Zeel K Soni Sandipkumar P Bhatt Akash Mathuria Shrikalp S Deshpande Source Type: research

Genotype-Controlled Vertical Transmission Exerts Selective Pressure on Community Assembly of Salvia miltiorrhiza
Microb Ecol. 2023 Sep 4. doi: 10.1007/s00248-023-02295-7. Online ahead of print.ABSTRACTThe plant's endophytic fungi play an important role in promoting host development and metabolism. Studies have shown that the factors affecting the assembly of the endophyte community mainly include host genotype, vertical transmission, and soil origin. However, we do not know the role of vertically transmitted endohytic fungi influences on the host-plant's endophytic community assembly. Salvia miltiorrhiza from three production areas were used as research objects; we constructed three production area genotypes of S. miltiorrhiza regene...
Source: Microbial Ecology - September 4, 2023 Category: Microbiology Authors: Hongyang Lv Xiaoyu Li Dongmei He Xin Chen Min Liu Yin Lan Jin Zhao Hai Wang Zhuyun Yan Source Type: research

Effects of methomyl on the intestinal microbiome and hepatic transcriptome of tilapia, and the modifying effects of mint co-culture
In this study, we investigated the impact of MET on the antioxidant system of Oreochromis niloticus in presence of mint as a floating bed. Results revealed that the superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase, and glutathione S-transferase significantly decreased and the GSH content significantly increased in the intestine. The hepatic peroxisome proliferator-activated receptor (PPAR) signalling pathway, carbon metabolism, renal phosphoinositide 3-kinase (PI3K)-Akt, mitogen-activated protein kinase (MAPK) signalling pathway, and phagosomes were significantly affected. Upon long-term exposure, circadi...
Source: Aquatic Toxicology - September 4, 2023 Category: Toxicology Authors: Yao Zheng Benkhelifa Fateh Gangchun Xu Source Type: research

Aloperine Protects Pulmonary Hypertension via Triggering PPAR γ Signaling and Inhibiting Calcium Regulatory Pathway in Pulmonary Arterial Smooth Muscle Cells
In this study, monocrotaline-induced PH (MCT-PH) rat model and primarily cultured rat distal pulmonary arterial smooth muscle cells (PASMCs) were used to investigate the mechanisms of ALO on experimental PH, pulmonary vascular remodeling and excessive proliferation of PASMCs. Results showed that: Firstly, ALO significantly prevented the disease development of MCT-PH by inhibiting right ventricular systolic pressure (RVSP) and right ventricular hypertrophy indexed by Fulton Index, normalizing the pulmonary arterials (PAs) remodeling and improving the right ventricular function indexed by transthoracic echocardiography. ALO ...
Source: American Journal of Physiology. Cell Physiology - September 4, 2023 Category: Cytology Authors: Xiaoqian Shan Jing Wang Huazhuo Feng Zizhou Zhang Qiuyu Zheng Qing Zhang Kai Yang Jian Wang Lei Xu Source Type: research

Efficacy and Tolerability Evaluation of a Nutraceutical Composition Containing Vitex agnus-castus Extract (EVX40 ™), Pyridoxine, and Magnesium in Premenstrual Syndrome: A Real-World, Interventional, Comparative Study
Conclusion The results of the current study conclude that the nutraceutical composition of Vitex agnus-castus extract, vitamin B6, and magnesium is effective in reducing the severity of PMS symptoms and improving the quality of life of PMS subjects. The nutraceutical therapy provided greater relief from PMS symptoms compared to standard therapy alone, and this effect was augmented when the nutraceutical therapy was provided in combination with standard therapies. Similarly, the improvement in quality-of-life parameters was greater in subjects treated with nutraceuticals alone or in combination therapy. Despite the limitati...
Source: Pain Physician - September 4, 2023 Category: Anesthesiology Authors: Varun P Sureja Dharmeshkumar B Kheni Vishal P Dubey Jignesh Kansagra Zeel K Soni Sandipkumar P Bhatt Akash Mathuria Shrikalp S Deshpande Source Type: research