Efficacy and Tolerability Evaluation of a Nutraceutical Composition Containing Vitex agnus-castus Extract (EVX40 ™), Pyridoxine, and Magnesium in Premenstrual Syndrome: A Real-World, Interventional, Comparative Study

Conclusion The results of the current study conclude that the nutraceutical composition of Vitex agnus-castus extract, vitamin B6, and magnesium is effective in reducing the severity of PMS symptoms and improving the quality of life of PMS subjects. The nutraceutical therapy provided greater relief from PMS symptoms compared to standard therapy alone, and this effect was augmented when the nutraceutical therapy was provided in combination with standard therapies. Similarly, the improvement in quality-of-life parameters was greater in subjects treated with nutraceuticals alone or in combination therapy. Despite the limitations of the study, the results of the current study are promising, and the nutraceutical composition (Ezedayz®) can be effectively used in clinical settings to control symptoms and improve the quality of life of PMS patients.PMID:37664371 | PMC:PMC10472015 | DOI:10.7759/cureus.42832

Source: Pain Physician - September 4, 2023 Category: Anesthesiology Authors: Varun P Sureja Dharmeshkumar B Kheni Vishal P Dubey Jignesh Kansagra Zeel K Soni Sandipkumar P Bhatt Akash Mathuria Shrikalp S Deshpande Source Type: research