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Non-Opioid Perioperative Pain Strategies for the Clinician: A Narrative Review
AbstractAlternative and non-opioid options for pain management are necessary in perioperative patient care. Opioids are no longer touted as cure-all medications, and furthermore, there have been tremendous advances in alternative therapies such as in interventional pain, physical therapy, exercise, and nutritional counseling that have proven benefits to combat pain. The center for disease control now strongly recommends the use of multimodal analgesia and multidisciplinary approaches based on the individual needs of patients: personalized medicine. In this manuscript, the specifics of non-opioid pharmacological and non-pha...
Source: Pain and Therapy - January 12, 2020 Category: Anesthesiology Source Type: research

The Routes of Administration for Acute Postoperative Pain Medication
AbstractEffective treatment of postoperative acute pain, together with early mobilization and nutrition, is one of the perioperative strategies advocated to improve surgical outcome and reduce the costs of hospitalization. Moreover, adequate pain control reduces perioperative morbidity related to surgical stress and can also prevent the incidence of chronic postoperative pain syndromes, whose treatment is still a challenge. The choice of the most appropriate analgesics depends not only on the drug class, but also on the most suitable route of administration, the best dosage for that route, and unique limitations and contra...
Source: Pain and Therapy - July 17, 2021 Category: Anesthesiology Source Type: research

Substituting Cannabidiol for Opioids and Pain Medications Among Individuals with Fibromyalgia: a Large Online Survey
Fibromyalgia (FM) is a common chronic pain condition that affects 2-4% of the population.15 People with FM typically experience widespread pain and co-occurring symptoms, including fatigue, sleep disturbances, and cognitive dysfunction.15 FM symptom management is difficult: non-pharmacological FM interventions (such as acupuncture, massage, and nutrition) are typically not covered by insurance and it can be difficult to find qualified practitioners for these non-pharmacological modalities.3, 7 Further, while there are three approved medications for FM (duloxetine, pregabalin, and milnacipran), these medications typically o...
Source: The Journal of Pain - May 12, 2021 Category: Materials Science Authors: Kevin F. Boehnke, Joel J. Gagnier, Lynne Matallana, David A. Williams Source Type: research

We cannot ignore nutrition ’ s impact on both pain and obesity
 An excerpt from Epigenetics and the Psychology of Weight Loss: How to Lose More Weight with Less Effort. We know that people with chronic pain are more likely to be obese; but does this happen because people with chronic pain struggle to exercise and suffer from a high load of stress hormones which promote stress Read more… We cannot ignore nutrition’s impact on both pain and obesity originally appeared in KevinMD.com.
Source: Kevin, M.D. - Medical Weblog - October 9, 2022 Category: General Medicine Authors: Tags: Conditions Nutrition Pain Management Source Type: blogs

Nutrition ’ s impact on pain and obesity PODCAST
Subscribe to The Podcast by KevinMD. Catch up on old episodes! “Both pain and obesity can have a multitude of causes. Therefore, reducing pain and body weight should be approached in a multifactorial way; nutritionally, physically, mentally, and emotionally. Failure to do so may result in short-term success but long-term failure.” Francisco M. Torres is an Read more… Nutrition’s impact on pain and obesity [PODCAST] originally appeared in KevinMD.com.
Source: Kevin, M.D. - Medical Weblog - December 16, 2022 Category: General Medicine Authors: Tags: Podcast Obesity Pain Management Source Type: blogs

Pro-inflammatory Dietary Intake Relates to Pain Sensitivity in Chronic Non-Specific Low Back Pain: A Case-Control Study
Non-specific chronic low back pain (nCLBP) has been associated with nutrition. Yet, it is not clear how nutritional factors and nCLBP relate to one another. Therefore, the aim of the present study was to investigate differences in diet quality and dietary intake levels between nCLBP patients and healthy controls (HCs) and to explore the association between nutritional factors and pain sensitivity in nCLBP. In this case-control study, 106 participants (i.e., n=53 nCLBP and n=53 HCs) were recruited and completed a 3-day food diary to assess their dietary intake, which allowed to generate individual diet quality scores, (i.e....
Source: The Journal of Pain - August 30, 2023 Category: Materials Science Authors: Ömer Elma, Sevilay Tumkaya Yilmaz, Jo Nijs, Peter Clarys, Iris Coppieters, Evelien Mertens, Tom Deliens, Anneleen Malfliet Source Type: research

Proinflammatory Dietary Intake Relates to Pain Sensitivity in Chronic Nonspecific Low Back Pain: A Case-Control Study
Nonspecific chronic low back pain (nCLBP) has been associated with nutrition. Yet, it is not clear how nutritional factors and nCLBP relate to one another. Therefore, the aim of the present study was to investigate differences in diet quality and dietary intake levels between nCLBP patients and healthy controls (HCs) and explore the association between nutritional factors and pain sensitivity in nCLBP. In this case-control study, 106 participants (ie, n  = 53 nCLBP and n = 53 HCs) were recruited and completed a 3-day food diary to assess their dietary intake, which allowed to generate individual diet quality scores (ie...
Source: The Journal of Pain - August 30, 2023 Category: Materials Science Authors: Ömer Elma, Sevilay Tümkaya Yılmaz, Jo Nijs, Peter Clarys, Iris Coppieters, Evelien Mertens, Tom Deliens, Anneleen Malfliet Tags: Original Reports Source Type: research

A Phenomenologic Study About the Dietary Habits and Digestive Complications for People Living with Temporomandibular Joint Disorder.
CONCLUSION: These findings highlight the need for health care providers to establish nutritional guidelines for TMD individuals at risk of physiologic and psychologic comorbidities. Health care intervention programs to treat people living with chronic TMD pain and that provide nutritional guidance will help decrease medical crises and the need for expensive interventions and will better assist these patients. PMID: 31247062 [PubMed - as supplied by publisher]
Source: Journal of Orofacial Pain - June 28, 2019 Category: ENT & OMF Tags: J Oral Facial Pain Headache Source Type: research

Serum Analysis in Patients with Temporomandibular Disorders: A Controlled Cross-Sectional Study in Norway.
Abstract Temporomandibular disorder (TMD) is characterized by pain and dysfunction in the temporomandibular join (TMJ) and the masticatory apparatus. Associations with autoimmune diseases, inflammatory conditions, and nutrition deficiencies have been reported in previous studies of TMD patients. To evaluate essential proteins, hormones, electrolytes, and vitamins in serum from TMD patients, a standard blood sample analysis was performed in 60 TMD patients and 60 healthy controls matched for age and gender, retrieving 19 different analyses. We found that TMD patients had significantly higher values of hemoglobin (p...
Source: Pain Research and Management - November 8, 2019 Category: Anesthesiology Authors: Staniszewski K, Lygre H, Berge T, Rosén A Tags: Pain Res Manag Source Type: research

A Treatment for Refractory High Ileostomy Output.
We present a case where the glucagon-like peptide 2 (GLP-2) analog teduglutide was used successfully to decrease high ostomy output due to short bowel syndrome in a patient not entirely dependent on parenteral nutrition. Short bowel syndrome is known to decrease quality of life and is associated with high health care costs. Although use has been limited by cost, teduglutide appears to be a treatment option for palliative care practice if patients suffer from short bowel syndrome. PMID: 30395777 [PubMed - as supplied by publisher]
Source: Journal of Pain and Palliative Care Pharmacotherapy - November 6, 2018 Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research

A Boy with Rash and Joint Pain Diagnosed with Scurvy: A Case Report
J Educ Teach Emerg Med. 2021 Oct 15;6(4):V6-V8. doi: 10.21980/J89H1X. eCollection 2021 Oct.ABSTRACTWhile rare, scurvy is a disease the emergency physician should continue to consider in the differential of bruising and joint pain. Although these symptoms are nonspecific, the astute physician should remain open-minded even when scurvy is not likely to be seen in an economically stable country. Contrary to this, we report a case of a young boy in the United States with scurvy who presented with a rash and limp. The diagnosis of scurvy can be made alone by a thorough history, but radiologic studies and pertinent labs also hel...
Source: Pain Physician - July 19, 2023 Category: Anesthesiology Authors: James Tran Yih Ying Eva Yuan Source Type: research

Differential Neuroplastic Changes in Fibromyalgia and Depression Indexed by Up-Regulation of Motor Cortex Inhibition and Disinhibition of the Descending Pain System: An Exploratory Study
Conclusion: These findings support the hypothesis that in FM a deteriorated function of cortical inhibition, indexed by a higher SICI parameter, a lower function of the DPMS, together with a higher level of BDNF indicate that FM has different pathological substrates from depression. They suggest that an up-regulation phenomenon of intracortical inhibitory networks associated with a disruption of the DPMS function occurs in FM. Introduction Major depressive disorder (MDD) and fibromyalgia (FM) present overlapped symptoms. Although the connection between these two disorders has not been elucidated yet, the disruption...
Source: Frontiers in Human Neuroscience - April 24, 2019 Category: Neuroscience Source Type: research

Association of Pain and Impact of Dual-Task Exercise on Function, Cognition and Quality of Life
ConclusionProactive efforts are required to screen for pain and manage frailty, sarcopenia and depression. Dual-task exercise proved safe and possibly effective in reducing pain and improving QOL, physical and cognitive function in older adults. Prospective randomized studies are needed to validate the effectiveness of dual-task vs single-task exercise, including impact of reversal of frailty and sarcopenia in pain management.
Source: The Journal of Nutrition, Health and Aging - September 9, 2021 Category: Nutrition Source Type: research

The Strong Correlation Between Pain Interference and Abnormal Nutritional Status in Older Adults With Chronic Musculoskeletal Pain
CONCLUSIONS: This study reports a strong correlation between pain interference and nutritional status. Therefore, pain interference can be a useful pain assessment tool to indicate risk of abnormal nutritional status in older adults. In addition, related factors, including age, underweight, and hypertension, were associated with a higher risk of malnutrition.PMID:37199383 | DOI:10.1177/21501319231174116
Source: Primary Care - May 18, 2023 Category: Primary Care Authors: Narucha Komolsuradej Siwaluk Srikrajang Norrapat Rangsiprakarn Arya Wongaree Chonnapat Wasusathapon Darat Kanjanakomut Vannarat Nukaew Wannasak Cheutalay Suppawit Kaewpipat Sirinkit Hoonthong Sochealing Ung Khanin Iamthanaporn Source Type: research