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Linseed oil attenuates fatty liver disease in mice fed a high-carbohydrate diet
In conclusion, linseed oil impedes or reduces the liver injury progression induced by an HCD.PMID:37703111 | PMC:PMC10496762 | DOI:10.1590/1414-431X2023e12927
Source: Braz J Med Biol Res - September 13, 2023 Category: Research Authors: G Godoy C C O Bernardo L Casagrande M L M S érgio J N Zanoni J V C M Perles R Curi R B Bazotte Source Type: research
The < em > Ustilago maydis < /em > AA10 LPMO is active on fungal cell wall chitin
In this study, we successfully produced the catalytic domain of this LPMO (UmAA10_cd) in Pichia pastoris and carried out its biochemical characterization. Our results show that UmAA10_cd oxidatively cleaves α- and β-chitin with C1 regioselectivity and boosts chitin hydrolysis by a GH18 chitinase from U. maydis (UmGH18A). Using a biologically relevant substrate, we show that UmAA10_cd exhibits enzymatic activity on U. maydis fungal cell wall chitin and promotes its hydrolysis by UmGH18A. These results represent an important step toward the understanding of the role of LPMOs in the fungal cell wall remodeling process durin...
Source: Applied and Environmental Microbiology - September 13, 2023 Category: Microbiology Authors: Roseline Assiah Yao Jean-Lou Reyre Ketty C Tamburrini Mireille Haon Olivier Tranquet Akshay Nalubothula Saumashish Mukherjee Sophie Le Gall Sacha Grisel Sonia Longhi Jogi Madhuprakash Bastien Bissaro Jean-Guy Berrin Source Type: research
Linseed oil attenuates fatty liver disease in mice fed a high-carbohydrate diet
In conclusion, linseed oil impedes or reduces the liver injury progression induced by an HCD.PMID:37703111 | PMC:PMC10496762 | DOI:10.1590/1414-431X2023e12927
Source: Braz J Med Biol Res - September 13, 2023 Category: Research Authors: G Godoy C C O Bernardo L Casagrande M L M S érgio J N Zanoni J V C M Perles R Curi R B Bazotte Source Type: research
The < em > Ustilago maydis < /em > AA10 LPMO is active on fungal cell wall chitin
In this study, we successfully produced the catalytic domain of this LPMO (UmAA10_cd) in Pichia pastoris and carried out its biochemical characterization. Our results show that UmAA10_cd oxidatively cleaves α- and β-chitin with C1 regioselectivity and boosts chitin hydrolysis by a GH18 chitinase from U. maydis (UmGH18A). Using a biologically relevant substrate, we show that UmAA10_cd exhibits enzymatic activity on U. maydis fungal cell wall chitin and promotes its hydrolysis by UmGH18A. These results represent an important step toward the understanding of the role of LPMOs in the fungal cell wall remodeling process durin...
Source: Applied and Environmental Microbiology - September 13, 2023 Category: Microbiology Authors: Roseline Assiah Yao Jean-Lou Reyre Ketty C Tamburrini Mireille Haon Olivier Tranquet Akshay Nalubothula Saumashish Mukherjee Sophie Le Gall Sacha Grisel Sonia Longhi Jogi Madhuprakash Bastien Bissaro Jean-Guy Berrin Source Type: research
Secondary analysis of a randomized trial testing community health educator interventions for diabetes prevention among refugees with depression: effects on nutrition, physical activity and sleep
CONCLUSIONS: CHEs may improve nutrition and physical activity in refugees with depression but more intensive interventions may be required to impact sleep. Improvements in all three behaviors appear to be associated with HbA1c lowering TRIAL REGISTRATION: ClinicalTrials.gov identifier NCT02502929.PMID:37700288 | DOI:10.1186/s12966-023-01509-y
Source: Health Physics - September 12, 2023 Category: Physics Authors: Julie A Wagner Angela Berm údez-Millán Thomas E Buckley Orfeu M Buxton Richard S Feinn Sengly Kong Theanvy Kuoch Lindsay Master Mary F Scully Source Type: research
Retraction Note: The relationship of double-stranded DNA breaks in blood lymphocytes and obesity without carbohydrate metabolism disorder
Mol Cell Biochem. 2023 Sep 13. doi: 10.1007/s11010-023-04852-7. Online ahead of print.NO ABSTRACTPMID:37700220 | DOI:10.1007/s11010-023-04852-7
Source: Molecular and Cellular Biochemistry - September 12, 2023 Category: Biochemistry Authors: Khatimya Kudabayeva Yerlan Bazargaliyev Raikul Kosmuratova Source Type: research
Utilization of local therapeutic food in preventing and treating nutrition problems in the dry land area of the islands of east nusa tenggara province
J Adv Pharm Technol Res. 2023 Jul-Sep;14(3):253-257. doi: 10.4103/japtr.japtr_38_23. Epub 2023 Jul 28.ABSTRACTThe research aims to produce a local Pemberian makanan tambahan (PMT) biscuit formula that is nutritious, acceptable and has a good shelf life. Experimental research with RAL design used two factors and two treatments, namely the addition of anchovy flour (20% and 30%) and moringa leaf flour (20% and 30%) to 100 g of corn flour. The research was conducted in April-November 2022 with an analysis of nutritional content, and acceptability. Data were processed using SPSS with a statistical test One Way analysis of vari...
Source: Adv Data - September 11, 2023 Category: Epidemiology Authors: Intje Picauly Marselinus Laga Nur Marni Marni Esryk Indriyani Kale Source Type: research
Dietary habits among snus users: a population-based cross-sectional study
CONCLUSION: We observed that snus users had an unhealthier diet than never tobacco users. Future studies on the association between snus use and health outcomes should, therefore, consider diet as a potential confounder.PMID:37691745 | PMC:PMC10492228 | DOI:10.29219/fnr.v67.9537
Source: Food and Nutrition Research - September 11, 2023 Category: Nutrition Authors: Fanny Berglund Johanna T örmä Maria Wennberg Patrik Wennberg Viktor Oskarsson Source Type: research
Molecular Bases of Protein Antigenicity and Determinants of Immunogenicity, Anergy, and Mitogenicity
CONCLUSION: The epitopes of an antigen are located in surface areas; they are about 880-3,300 Da in size. They are protein, carbohydrate, or lipid in nature. Soluble antigens are smaller than 1 nm and are endocytosed less efficiently than particulate antigens. The more the structural complexity of an antigen increases, the more the antigenicity increases due to the number and variety of epitopes. The smallest immunogens are about 4,000-10,000 Da in size. The more phylogenetically distant immunogens are from the immunogen-recipient, the more immunogenicity increases. Antigens that are immunogens can trigger an innate or ada...
Source: Protein and Peptide Letters - September 11, 2023 Category: Biochemistry Authors: David Pedroza-Escobar Irais Castillo-Maldonado Tania Gonz ález-Cortés Dealmy Delgadillo-Guzm án Pablo Ru íz-Flores Jorge Haro Santa Cruz Perla-Karina Karina Espino-Silva Erika Flores-Loyola Agustina Ramirez-Moreno Joaqu ín Avalos-Soto Miguel- Ángel Source Type: research
Mannan oligosaccharides selenium ameliorates intestinal mucosal barrier, and regulate intestinal microbiota to prevent Enterotoxigenic Escherichia coli -induced diarrhea in weaned piglets
In conclusion, our study showed that dietary MOSS supplementation ameliorated intestinal mucosa barrier, and regulated intestinal microbiota to prevent ETEC induced diarrhea in weaned piglets.PMID:37696080 | DOI:10.1016/j.ecoenv.2023.115448
Source: Ecotoxicology and Environmental Safety - September 11, 2023 Category: Environmental Health Authors: Andong Zha Ruiqi Tu Ming Qi Jing Wang Bie Tan Peng Liao Chenchen Wu Yulong Yin Source Type: research
