Filtered By:
Nutrition: Carbohydrates
This page shows you your search results in order of date. This is page number 4.
Order by Relevance | Date
Total 19250 results found since Jan 2013.
Synthesis of fluorinated and nonfluorinated sugar alkenylphosphonates via highly stereoselective Horner-Wadsworth-Emmons olefination
Carbohydr Res. 2023 Sep 13;533:108941. doi: 10.1016/j.carres.2023.108941. Online ahead of print.ABSTRACTNew fluorinated and nonfluorinated sugar alkenylphosphonates were obtained. In all cases 1,2;5,6-di-O-isopropylidene-α-d-glucofuranose was used as the starting material. The synthesis of alkenylphosphonates was based on Horner-Wadsworth-Emmons olefination. The process led to products with E-stereochemistry exclusively or predominately.PMID:37717483 | DOI:10.1016/j.carres.2023.108941
Source: Carbohydrate Research - September 17, 2023 Category: Genetics & Stem Cells Authors: Monika Bilska-Markowska Marcin Ka źmierczak Source Type: research
Water-soluble fluorine-functionalized chitooligosaccharide derivatives: Synthesis, characterization and antimicrobial activity
Carbohydr Res. 2023 Sep 4;533:108935. doi: 10.1016/j.carres.2023.108935. Online ahead of print.ABSTRACTIn this work, a series of water-soluble fluorine-functionalized chitooligosaccharide derivatives were synthesized by conjugating nicotinic acid to chitooligosaccharide via nicotinylation reaction, followed by nucleophilic reaction with ethyl bromide, benzyl bromide and fluorobenzyl bromides. Synthesized derivatives were identified structurally by Fourier Transform Infrared Spectroscopy and Nuclear Magnetic Resonance. In addition, the antibacterial activities of chitooligosaccharide derivatives against several disease-caus...
Source: Carbohydrate Research - September 17, 2023 Category: Genetics & Stem Cells Authors: Conghao Lin Fang Luan Shengjia Su Aili Jiang Wenqiang Tan Zhanyong Guo Source Type: research
Transcriptome analysis of a springtail, Folsomia candida, reveals energy constraint and oxidative stress during petroleum hydrocarbon exposure
In this study, the effects of PHCs on conventional endpoints (i.e., survival and reproduction) and gene expression rates of a model springtail species, Folsomia candida were investigated. Age-synchronized F. candida were exposed to ecologically-relevant concentrations of soils spiked with fresh crude oil to calculate the reproductive EC25 and EC50 values using conventional toxicity testing. Soils spiked to these concentrations were then used to evaluate effects on the F. candida transcriptome over a 7-day exposure period. RNA-seq analysis found 98 and 132 differentially expressed genes when compared to the control for the ...
Source: Chemosphere - September 16, 2023 Category: Chemistry Authors: Adrian Pang Allison Rutter Elizabeth Haack Barbara Zeeb Source Type: research
Mikania micrantha Kunth: An Ethnopharmacological Treasure Trove of Therapeutic Potential
This study aimed at summarizing the traditional uses, phytochemical profile, and biological activities of M. micrantha based on obtainable information screened from different databases. The results suggest that fresh leaves and whole plant are frequently used in folk medicine. The plant contains more than 150 different phytochemicals under the following groups: essential oils, phenolics and flavonoids, terpenes, terpene lactones, glycosides, and sulfated flavonoids. It contains carbohydrates and micronutrients including vitamins and major and trace minerals. M. micrantha possesses antioxidant, anti-inflammatory, anti-micro...
Source: Chemistry and Biodiversity - September 16, 2023 Category: Biochemistry Authors: Muahmmad Ali Khan Dina M El-Kersh Md Shafiqul Islam Shams Ara Khan Hossam Kamli Chandan Sarkar Md Shimul Bhuia Tawhida Islam Manik Chandra Shill Glenda C Gobe Eda S önmez Gürer William N Setzer Javad Sharifi-Rad Muhammad Torequl Islam Source Type: research
Metagenome-assembled genomes reveal carbohydrate degradation and element metabolism of microorganisms inhabiting Tengchong hot springs, China
Environ Res. 2023 Sep 14:117144. doi: 10.1016/j.envres.2023.117144. Online ahead of print.ABSTRACTA hot spring is a distinctive aquatic environment that provides an excellent system to investigate microorganisms and their function in elemental cycling processes. Previous studies of terrestrial hot springs have been mostly focused on the microbial community, one special phylum or category, or genes involved in a particular metabolic step, while little is known about the overall functional metabolic profiles of microorganisms inhabiting the terrestrial hot springs. Here, we analyzed the microbial community structure and thei...
Source: Environmental Research - September 16, 2023 Category: Environmental Health Authors: Zhufeng Zhang Tao Liu Xudong Li Qing Ye Hina Iqbal Bangash Jinshui Zheng Nan Peng Source Type: research
User-friendly one-step disposable signal-on bioassay for glyphosate detection in water samples
Biosens Bioelectron. 2023 Sep 12;241:115689. doi: 10.1016/j.bios.2023.115689. Online ahead of print.ABSTRACTThe onsite detection of glyphosate requires an easy-to-handle, low-cost and disposable assay for untrained users as requested by the ASSURED guidelines. A new strategy based on the expression of fusion proteins is proposed here. A glyphosate oxidase derived from Bacillus subtilis and the 6E10 variant of the dye peroxidase from Pseudomonas putida, both fused with the carbohydrate binding module (CBM) 3a from Clostridium thermocellum, were designed and expressed, leading to GlyphOx-CBM and 6E10-CBM. Cell lysates were u...
Source: Biosensors and Bioelectronics - September 16, 2023 Category: Biotechnology Authors: N Delprat L O Martins L J Blum C M G Aymard B Leca-Bouvier G Octobre B Doum èche Source Type: research
A metabolomic investigation of serum perfluorooctane sulfonate and perfluorooctanoate
CONCLUSIONS: In this large metabolomic study, we observed robust positive associations with PFOS for several molecules. Further investigation of these metabolites may offer insight into PFOS-related biologic effects.PMID:37716341 | DOI:10.1016/j.envint.2023.108198
Source: Cancer Control - September 16, 2023 Category: Cancer & Oncology Authors: Jongeun Rhee Erikka Loftfield Demetrius Albanes Tracy M Layne Rachael Stolzenberg-Solomon Linda M Liao Mary C Playdon Sonja I Berndt Joshua N Sampson Neal D Freedman Steven C Moore Mark P Purdue Source Type: research
Ligand-Directed Chemistry on Glycoside Hydrolases - A Proof of Concept Study
Chembiochem. 2023 Sep 16:e202300480. doi: 10.1002/cbic.202300480. Online ahead of print.ABSTRACTSelective covalent labelling of enzymes using small molecule probes has advanced the scopes of protein profiling. The covalent bond formation to a specific target is the key step of activity-based protein profiling (ABPP), a method which has become an indispensable tool for measuring enzyme activity in complex matrices. With respect to carbohydrate processing enzymes, strategies for ABPP so far involve labelling the active site of the enzyme, which results in permanent loss of activity. Here, we report in a proof of concept stud...
Source: Chembiochem - September 16, 2023 Category: Biochemistry Authors: Herwig Prasch Andreas Wolfsgruber Martin Thonhofer Andr é Culum Christoph Mandl Patrick Weber Melanie Z ündel Seyed A Nasseri Andres Gonzalez Santana Gregor Tegl Bernd Nidetzky Karl Gruber Arnold E St ütz Stephen G Withers Tanja M Wrodnigg Source Type: research
Transcriptome analysis of a springtail, Folsomia candida, reveals energy constraint and oxidative stress during petroleum hydrocarbon exposure
In this study, the effects of PHCs on conventional endpoints (i.e., survival and reproduction) and gene expression rates of a model springtail species, Folsomia candida were investigated. Age-synchronized F. candida were exposed to ecologically-relevant concentrations of soils spiked with fresh crude oil to calculate the reproductive EC25 and EC50 values using conventional toxicity testing. Soils spiked to these concentrations were then used to evaluate effects on the F. candida transcriptome over a 7-day exposure period. RNA-seq analysis found 98 and 132 differentially expressed genes when compared to the control for the ...
Source: Chemosphere - September 16, 2023 Category: Chemistry Authors: Adrian Pang Allison Rutter Elizabeth Haack Barbara Zeeb Source Type: research
Ligand-Directed Chemistry on Glycoside Hydrolases - A Proof of Concept Study
Chembiochem. 2023 Sep 16:e202300480. doi: 10.1002/cbic.202300480. Online ahead of print.ABSTRACTSelective covalent labelling of enzymes using small molecule probes has advanced the scopes of protein profiling. The covalent bond formation to a specific target is the key step of activity-based protein profiling (ABPP), a method which has become an indispensable tool for measuring enzyme activity in complex matrices. With respect to carbohydrate processing enzymes, strategies for ABPP so far involve labelling the active site of the enzyme, which results in permanent loss of activity. Here, we report in a proof of concept stud...
Source: Chembiochem - September 16, 2023 Category: Biochemistry Authors: Herwig Prasch Andreas Wolfsgruber Martin Thonhofer Andr é Culum Christoph Mandl Patrick Weber Melanie Z ündel Seyed A Nasseri Andres Gonzalez Santana Gregor Tegl Bernd Nidetzky Karl Gruber Arnold E St ütz Stephen G Withers Tanja M Wrodnigg Source Type: research
Mikania micrantha Kunth: An Ethnopharmacological Treasure Trove of Therapeutic Potential
This study aimed at summarizing the traditional uses, phytochemical profile, and biological activities of M. micrantha based on obtainable information screened from different databases. The results suggest that fresh leaves and whole plant are frequently used in folk medicine. The plant contains more than 150 different phytochemicals under the following groups: essential oils, phenolics and flavonoids, terpenes, terpene lactones, glycosides, and sulfated flavonoids. It contains carbohydrates and micronutrients including vitamins and major and trace minerals. M. micrantha possesses antioxidant, anti-inflammatory, anti-micro...
Source: Chemistry and Biodiversity - September 16, 2023 Category: Biochemistry Authors: Muahmmad Ali Khan Dina M El-Kersh Md Shafiqul Islam Shams Ara Khan Hossam Kamli Chandan Sarkar Md Shimul Bhuia Tawhida Islam Manik Chandra Shill Glenda C Gobe Eda S önmez Gürer William N Setzer Javad Sharifi-Rad Muhammad Torequl Islam Source Type: research
A metabolomic investigation of serum perfluorooctane sulfonate and perfluorooctanoate
CONCLUSIONS: In this large metabolomic study, we observed robust positive associations with PFOS for several molecules. Further investigation of these metabolites may offer insight into PFOS-related biologic effects.PMID:37716341 | DOI:10.1016/j.envint.2023.108198
Source: Environment International - September 16, 2023 Category: Environmental Health Authors: Jongeun Rhee Erikka Loftfield Demetrius Albanes Tracy M Layne Rachael Stolzenberg-Solomon Linda M Liao Mary C Playdon Sonja I Berndt Joshua N Sampson Neal D Freedman Steven C Moore Mark P Purdue Source Type: research
