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Total 22 results found since Jan 2013.

Effects of Low-Frequency Repetitive Transcranial Magnetic Stimulation Combined with Intensive Speech Therapy on Cerebral Blood Flow in Post-Stroke Aphasia
Abstract We provided an intervention to chronic post-stroke aphasic patients using low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) guided by a functional magnetic resonance imaging (fMRI) evaluation of language laterality, combined with intensive speech therapy (ST). We performed a single photon emission-computed tomography (SPECT) scan pre- and post-intervention and investigated the relationship between cerebral blood flow (CBF) and language function. Fifty right-handed chronic post-stroke aphasic patients were enrolled in the study. During their 11-day hospital admission, the patients receiv...
Source: Translational Stroke Research - August 7, 2015 Category: Neurology Source Type: research

A right convergence area of the prefrontal lobe is involved in the improvement of semantic fluency in patients with post-stroke aphasia
CONCLUSION: The improvement of semantic fluency in subacute PSA patients may require the participation of the right convergence area of the prefrontal lobe.PMID:37651207 | DOI:10.1080/10749357.2023.2253632
Source: Topics in Stroke Rehabilitation - August 31, 2023 Category: Neurology Authors: Tao Feng Chao Zhang Siwei Xu Lingmin Wang Kai Xu Zhiyuan Xie Jie Xiang Weiwei Chen Source Type: research

Corticospinal Tract Integrity and Long-Term Hand Function Prognosis in Patients With Stroke
Conclusions: The present study showed that CST integrity (at 6 months after onset) in patients with chronic stroke was related to functional hand status. In addition, the mid-pons FA value was more predictive of functional restoration of the hand than the FN or FA value at the pontomedullary junction. These results may be useful in predicting the functional restoration of the hand and understanding the functional prognosis of stroke. Introduction Restoration of hand function is one of the most important goals for patients with stroke (1). Thus, techniques that aid in predicting restoration of hand function are also i...
Source: Frontiers in Neurology - April 14, 2019 Category: Neurology Source Type: research

Recovery of Apraxia of Speech and Aphasia in Patients With Hand Motor Impairment After Stroke
Conclusion: Our findings confirm the common occurrence of AOS and aphasia in left hemisphere stroke patients with a hand motor impairment. Recovery was similar across speech-language and motor domains, even in patients with severe impairment, supporting the shared recovery hypothesis and that similar brain recovery mechanisms are involved in speech-language and motor recovery post stroke. These observations contribute to the knowledge of AOS and its relation to motor and language functions and add information that may serve as a basis for future studies of post stroke recovery. Studies including neuroimaging and/or biologi...
Source: Frontiers in Neurology - March 31, 2021 Category: Neurology Source Type: research

Cortical and Subcortical Control of Swallowing-Can We Use Information From Lesion Locations to Improve Diagnosis and Treatment for Patients With Stroke?
Conclusions Stroke lesion locations have been identified that are commonly associated across patients with the occurrence and recovery of dysphagia, suggesting that clinical brain scans provide useful information for improving the diagnosis and treatment of patients with stroke. However, individual differences in brain structure and function limit the generalizability of these relationships and emphasize that the extent of the motor and sensory pathology in swallowing, and how the patient recovers, also depends on a patient's individual brain constitution. The involvement of the damaged brain tissue in swallowing control b...
Source: American Journal of Speech-Language Pathology - July 9, 2020 Category: Speech-Language Pathology Authors: Wilmskoetter J, Daniels SK, Miller AJ Tags: Am J Speech Lang Pathol Source Type: research

Neuroanatomical Correlates of Macrolinguistic Aspects in Narrative Discourse in Unilateral Left and Right Hemisphere Stroke: A Voxel-Based Morphometry Study
This study aimed to investigate this relationship in a group of participants with middle-low to low socioeconomic status. Method Twenty adults with unilateral left hemisphere (n = 10) or right hemisphere (n = 10) chronic ischemic stroke and 10 matched (age, education, and socioeconomic status) healthy controls produced three oral narratives based on sequential scenes. Voxel-based morphometry analysis was conducted using structural magnetic resonance imaging. Results Compared to healthy controls, the left hemisphere group showed cohesion impairments, whereas the right hemisphere group showed impairments in coherence and in ...
Source: Journal of speech, language, and hearing research : JSLHR - April 12, 2021 Category: Speech-Language Pathology Authors: Fernanda Schneider Karine Marcotte Amelie Brisebois Sabrine Amaral Martins Townsend Anderson Dick Smidarle Fernanda Loureiro Alexandre da Rosa Franco Ricardo Bernardi Soder Alexandre Nikolaev Luiz Carlos Porcello Marrone Lilian Cristine H übner Source Type: research

Non-fluent aphasia and neural reorganization after speech therapy: insights from human sleep electrophysiology and functional magnetic resonance imaging.
Authors: Sarasso S, Santhanam P, Määtta S, Poryazova R, Ferrarelli F, Tononi G, Small SL Abstract Stroke is associated with long-term functional deficits. Behavioral interventions are often effective in promoting functional recovery and plastic changes. Recent studies in normal subjects have shown that sleep, and particularly slow wave activity (SWA), is tied to local brain plasticity and may be used as a sensitive marker of local cortical reorganization after stroke. In a pilot study, we assessed the local changes induced by a single exposure to a therapeutic session of IMITATE (Intensive Mouth Imitation and Tal...
Source: Archives Italiennes de Biologie - November 25, 2014 Category: Neuroscience Tags: Arch Ital Biol Source Type: research

Brain-Derived Neurotrophic Factor Genotype-Specific Differences in Cortical Activation in Chronic Aphasia.
Conclusion BDNF genotype mediates cortical brain activation in individuals with chronic aphasia. Correspondingly, individuals carrying the Met allele present with more severe aphasia compared to noncarriers. These findings warrant further study into the effects of BDNF genotype in aphasia. Supplemental Material https://doi.org/10.23641/asha.10073147 Presentation Video https://doi.org/10.23641/asha.10257581. PMID: 31756156 [PubMed - in process]
Source: Journal of speech, language, and hearing research : JSLHR - November 21, 2019 Category: Speech-Language Pathology Authors: Kristinsson S, Yourganov G, Xiao F, Bonilha L, Stark BC, Rorden C, Basilakos A, Fridriksson J Tags: J Speech Lang Hear Res Source Type: research

rTMS treatments combined with speech training for a conduction aphasia patient: A case report with MRI study
We report the case of a 39-year-old woman who was initially diagnosed with conduction aphasia following a left hemisphere stroke. Interventions: The rTMS location comprised the left Broca area, and a frequency of 5 Hz for 20 min/d for 10 days during a 2-week period was used. She had received speech rehabilitation training 1 month after stroke. Functional magnetic resonance imaging (fMRI) and diffusion tensor imaging were used to investigate the functional and microstructural changes before and after rTMS treatment. Outcomes: The results demonstrated that the Western Aphasia Battery scores significantly improved for l...
Source: Medicine - August 1, 2017 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Resting-State Functional Magnetic Resonance Imaging Connectivity Between Semantic and Phonological Regions of Interest May Inform Language Targets in Aphasia.
Conclusions Network connectivity of brain regions associated with semantic-phonological processing is predictive of language performance in poststroke aphasia. The most predictive connections involved right-hemisphere ROIs-particularly those for which structural adaptions are known to associate with recovered word retrieval performance. Predictions may be made, based on these findings, about which connections have potential as targets for neuroplastic functional changes with intervention in aphasia. Supplemental Material https://doi.org/10.23641/asha.12735785. PMID: 32755498 [PubMed - as supplied by publisher]
Source: Journal of speech, language, and hearing research : JSLHR - August 4, 2020 Category: Speech-Language Pathology Authors: Ramage AE, Aytur S, Ballard KJ Tags: J Speech Lang Hear Res Source Type: research

Diffusion tensor imaging magnetic resonance imaging (DTI-MRI) helps to tailor speech therapy: A case report with a short narrative review
CONCLUSION: Brain MRI is confirmed as a multimodal tool evaluating the damage, both from the point of structural and functional view. Tractography in aphasia allows focusing on major pathways. The involvement of the arcuate fascicle, whose lesion disconnects Broca's and Wernicke's areas, is related to clinical improvement, and represents a neural correlate of the brain injury recovery process that physicians and speech therapists might be aware of it, tailoring the plane of care of each patient.PMID:37638456 | DOI:10.3233/NRE-230082
Source: NeuroRehabilitation - August 28, 2023 Category: Rehabilitation Authors: Di Lorenzo Luigi Franco Carmine Muccio Source Type: research