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Carotid spot sign: an early marker of carotid artery injury (P5.162)
Conclusion TBI patients need prompt evaluation for TVI. A hyperdense artery sign is an early indicator of TVI in patients with otherwise normal CT and non-focal exam.Disclosure: Dr. Gyang has nothing to disclose. Dr. Latorre has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Gyang, T., Latorre, J. Tags: Cerebrovascular Disease and Interventional Neurology: Dissection Source Type: research

Review Epidemiology, pathophysiology, diagnosis, and management of intracranial artery dissection
Spontaneous intracranial artery dissection is an uncommon and probably underdiagnosed cause of stroke that is defined by the occurrence of a haematoma in the wall of an intracranial artery. Patients can present with headache, ischaemic stroke, subarachnoid haemorrhage, or symptoms associated with mass effect, mostly on the brainstem. Although intracranial artery dissection is less common than cervical artery dissection in adults of European ethnic origin, intracranial artery dissection is reportedly more common in children and in Asian populations.
Source: Lancet Neurology - May 11, 2015 Category: Neurology Authors: Stéphanie Debette, Annette Compter, Marc-Antoine Labeyrie, Maarten Uyttenboogaart, Tina M Metso, Jennifer J Majersik, Barbara Goeggel-Simonetti, Stefan T Engelter, Alessandro Pezzini, Philippe Bijlenga, Andrew M Southerland, Olivier Naggara, Yannick Béj Tags: Review Source Type: research

Epidemiology, pathophysiology, diagnosis, and management of intracranial artery dissection
Publication date: June 2015 Source:The Lancet Neurology, Volume 14, Issue 6 Author(s): Stéphanie Debette , Annette Compter , Marc-Antoine Labeyrie , Maarten Uyttenboogaart , Tina M Metso , Jennifer J Majersik , Barbara Goeggel-Simonetti , Stefan T Engelter , Alessandro Pezzini , Philippe Bijlenga , Andrew M Southerland , Olivier Naggara , Yannick Béjot , John W Cole , Anne Ducros , Giacomo Giacalone , Sabrina Schilling , Peggy Reiner , Hakan Sarikaya , Janna C Welleweerd , L Jaap Kappelle , Gert Jan de Borst , Leo H Bonati , Simon Jung , Vincent Thijs , Juan J Martin , Tobias Brandt , Caspar Grond-Ginsbach , Manja Klos...
Source: The Lancet Neurology - May 11, 2015 Category: Neurology Source Type: research

Intracranial Cerebral Artery Dissection of Anterior Circulation as a Cause of Convexity Subarachnoid Hemorrhage
Conclusion: Our data suggest that cSAH caused by intracranial cerebral artery dissection is not rare. Further investigations are needed to elucidate the precise mechanism underlying cSAH in cerebral artery dissection.Cerebrovasc Dis 2015;40:45-51
Source: Cerebrovascular Diseases - June 16, 2015 Category: Neurology Source Type: research

“Phacing” a New Cause of Carotid Artery Dissection
Conclusions: Noteworthy, among vascular abnormalities of PHACE, CADs have never been reported before. Our 2 cases suggest that CAD is an underecognized cerebrovascular manifestation of PHACE and it should be searched for in these patients. Ultrasound, being noninvasive and portable, is a useful tool for the assessment and follow-up of these patients.
Source: The Neurologist - March 1, 2017 Category: Neurology Tags: Case Report/Case Series Source Type: research

Association Between Migraine and Cervical Artery Dissection
This cohort study examines the association between migraine and ischemic stroke due to cervical artery dissection in young patients with ischemic stroke.
Source: JAMA Neurology - March 6, 2017 Category: Neurology Source Type: research

Spontaneous cervical artery dissection is accompanied by a hypercoagulable state and simultaneous inflammatory condition
ConclusionWe found evidence for a hypercoagulable state in patients with sCAD as indicated by a shortened aPTT, which was associated with a trend to an increased leucocyte count at the same time. Our findings first strengthen the hypothesis that inflammation critically impacts on the occurrence of sCAD, and second linked this condition with a marked affection of the coagulation system.
Source: Journal of Neurology - December 9, 2017 Category: Neurology Source Type: research

Imaging of Spontaneous and Traumatic Cervical Artery Dissection
ConclusionNeuroradiologists should be aware that intimal flaps and multivessel dissections are more common after a traumatic etiology. In addition, it seems important to conduct a  CTA in a trauma setting, even if no cervical spine fracture is detected.
Source: Clinical Neuroradiology - January 26, 2018 Category: Neurology Source Type: research

University education and cervical artery dissection
ConclusionWe observed a higher rate of university education in patients with CeAD compared with non-CeAD patients in our study population. University education was associated with favorable outcome in CeAD-patients. The mechanism behind this association remains unclear.
Source: Journal of Neurology - February 24, 2018 Category: Neurology Source Type: research

Active Reperfusion Hemorrhage during Thrombectomy: Angiographic Findings and Real-Time Correlation with the CT “Spot Sign”
Conclusions: Active reperfusion hemorrhage involving perforator arteries was observed to correlate with the CT “spot sign” and to be associated with poor outcomes.Intervent Neurol 2018;7:370 –377
Source: Interventional Neurology - June 8, 2018 Category: Neurology Source Type: research

Natural History of Cervical Artery Fibromuscular Dysplasia and Associated Neurovascular Events
Conclusions: No new cervical artery FMD or aneurysm was observed on subsequent imaging. New carotid dissection was uncommon over a mean follow-up period of 35.3 ± 25.3 months and was the only non-atherosclerotic vascular event observed after FMD diagnosis.Cerebrovasc Dis 2018;46:33 –39
Source: Cerebrovascular Diseases - July 31, 2018 Category: Neurology Source Type: research

Bilateral Hypoglossal Nerve Palsy in an Adult Patient With Repaired Tetralogy of Fallot
Conclusions: This is the first case of multiple-vessel sCAD, and more associated with an unusual clinical presentation, in a patient with surgically repaired ToF, supporting the hypothesis that defective large artery elastogenesis plays a role in this congenital disorder, and suggesting the importance of continuous long-term vascular follow-up.
Source: The Neurologist - September 1, 2018 Category: Neurology Tags: Case Report/Case Series Source Type: research

Antiplatelet Therapy vs Anticoagulation in Cervical Artery Dissection
This randomized clinical trial examines whether antiplatelent or anticoagulant therapy is more effective in preventing stroke in cervical dissection and the risk of recurrent stroke in a randomized clinical trial setting.
Source: JAMA Neurology - February 25, 2019 Category: Neurology Source Type: research

Rivaroxaban in cervical and “cervico-cerebral” artery dissections: a new therapeutic option?
We describe four cases of CADs and, firstly in literature, cervico-cerebral (CCADs) in young patients (average age of 42  years) treated with rivaroxaban 20 mg daily. Three of these four dissections had affected the vertebral artery (condition with an unfavorable prognosis and more often complicated by subarachnoid hemorrhages), and the other one was a carotid dissection at the extra-intracranial passage. All patien ts were followed clinically and with serial neurosonological examinations at 1, 3, and 6 months and with magnetic resonance angiography (MRA) at 6 months. All patients presented a good outcome with vascular...
Source: Neurological Sciences - April 11, 2019 Category: Neurology Source Type: research

Cervical arterial dissection: clinical characteristics in a neurology service in São Paulo, Brazil
Conclusion: The presence of atherosclerotic disease is considered rare in patients with cervical arterial dissection; however, our study found a high frequency of hypertension, smoking and dyslipidemia. The choice of antithrombotic remains controversial and will depend on the judgment of the medical professional; the clinical results with anticoagulation or antiaggregation were similar but there was more recanalization in the group treated with anticoagulation; its course was favorable in both situations. The recurrence of cervical arterial dissection and stroke is considered a rare event and its course is favorable.RESUMO...
Source: Arquivos de Neuro-Psiquiatria - September 23, 2019 Category: Neurology Source Type: research

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