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Collateral Score and Neurologic Worsening in Patients with Carotid Dissection (P1.002)
CONCLUSIONS: We did not find a significant association between the CS and neurologic worsening or recurrent stroke in patients with carotid dissection. Limitations include small sample size and retrospective nature.Disclosure: Dr. Jia has nothing to disclose. Dr. Cai has nothing to disclose. Dr. Rahbar has nothing to disclose. Dr. Pandurengan has nothing to disclose. Dr. Sarraj has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Jia, J., Cai, C., Rahbar, M., Pandurengan, R., Sarraj, A. Tags: Cerebrovascular Disease and Interventional Neurology Poster Discussion Session Source Type: research

Epidemiology and cerebrovascular events related to cervical and intracranial arteries dissection: the experience of the city of Pisa
This study aims to evaluate the incidence, clinical features, and outcome of cerebrovascular events related to sCAD and spontaneous intracranial arteries dissections (sIAD) in the city of Pisa (Italy). We retrospectively analyzed consecutive patients admitted between December 1997 and June 2015 with a diagnosis of stroke, TIA, or Bernard-Horner syndrome due to acute cervical or intracranial artery dissection. Considering that our hospital collects presumptively all patients hospitalized with sCAD coming from the referral geographical area, data may provide a good approximation to real incidence of sCAD in our population. C...
Source: Neurological Sciences - August 16, 2017 Category: Neurology Source Type: research

Incidence and Outcome of Vertebral Artery Dissection in Trauma Setting: Analysis of National Trauma Data Base
Conclusion Although infrequent, VAD in head and neck trauma is associated with higher rates of in-hospital stroke and longer length of ICU stay and total hospital stay. Early diagnosis and endovascular treatment may be an alternative option to reduce the rate of in-hospital stroke in these patients.
Source: Neurocritical Care - October 1, 2014 Category: Neurology Source Type: research

Prognostic significance of pulsatile tinnitus in cervical artery dissection
ConclusionThe presence of PT in CeAD is associated with a benign clinical course and predicts a favourable outcome.
Source: European Journal of Neurology - April 27, 2016 Category: Neurology Authors: L. Kellert, M. Kloss, A. Pezzini, S. Debette, D. Leys, V. Caso, V. N. Thijs, A. Bersano, E. Touzé, T. Tatlisumak, C. Traenka, P. A. Lyrer, S. T. Engelter, T. M. Metso, C. Grond‐Ginsbach, Tags: Original Article Source Type: research

Migraine and cerebrovascular diseases: Epidemiology, pathophysiological, and clinical considerations.
In conclusion, migraine is a potential risk factor for cerebrovascular diseases. Migraineurs should be carefully evaluated considering their vascular risk assessment based on current evidence, so that healthcare professionals can provide appropriate and individualized management of other cardiovascular risk factors, notably quitting smoking and restricting use of oral contraceptives. PMID: 30117565 [PubMed - as supplied by publisher]
Source: Headache - August 17, 2018 Category: Neurology Authors: Magalhães JE, Sampaio Rocha-Filho PA Tags: Headache Source Type: research

Long-term outcome of cervical artery dissection
AbstractLong-term consequences of cervical artery dissection (CeAD), a major cause of ischemic stroke in young people, have been poorly investigated. The Italian Project on Stroke at Young Age – Cervical Artery Dissection (IPSYS CeAD) project is a multicenter, hospital-based, consecutively recruiting, observational, cohort study aimed to address clinically important questions about long-term outcome of CeAD patients, which are not covered by other large-scale registries. Patients with r adiologically diagnosed CeAD were consecutively included in the registry. Baseline demographic and clinical variables, as well as inform...
Source: Neurological Sciences - May 11, 2020 Category: Neurology Source Type: research

Comment CADISS: a feasibility trial that answered its question
Anticoagulation after ischaemic stroke was a topic of major controversy for decades until a series of randomised clinical trials consistently showed no net benefit of heparin or warfarin compared with aspirin.1,2 Any reduction in the risk of recurrent ischaemic stroke was offset by an increase in risk of intracerebral haemorrhages. One cause of stroke for which the effect of anticoagulation remains unclear is cervical artery dissection. The classic dogma was that a tear in the intima leads to formation of a fibrin-rich thrombus and poses a very high risk of artery-to-artery embolism or occlusion, making early anticoagulati...
Source: Lancet Neurology - February 12, 2015 Category: Neurology Authors: Scott E Kasner Tags: Comment Source Type: research

Diagnosis and Treatment of Cervical Artery Dissection
Cervical artery dissection (CAD) is a major cause of stroke in the young. A mural hematoma is detected in most CAD patients. The intramural blood accumulation should not be considered a reason to withhold intravenous thrombolysis in patients with CAD-related stroke. Because intravenous-thrombolyzed CAD patients might not recover as well as other stroke patients, acute endovascular treatment is an alternative. Regarding the choice of antithrombotic agents, this article discusses the findings of 4 meta-analyses across observational data, the current status of 3 randomized controlled trials, and arguments and counterarguments...
Source: Neurologic Clinics - April 22, 2015 Category: Neurology Authors: Stefan T. Engelter, Christopher Traenka, Alexander Von Hessling, Philippe A. Lyrer Source Type: research

Migraine and the Risk of Carotid Artery Dissection
Stroke incidence is increasing among patients aged 40 to 60 years —faster than in older age cohorts. Preliminary evidence suggests that ischemic stroke—not hemorrhage or subarachnoid hemorrhage—accounts for the increase. Many speculate that increasing incidences of classic vascular risk factors among young patients contribute to the increased incidence of st roke. Certainly, we are all aware of the obesity epidemic and continued prevalence of smoking, leading to premature atherosclerosis. Furthermore, equally relevant causes of stroke in the young include migraine, drug abuse, cervical arterial dissections, patent fo...
Source: JAMA Neurology - March 6, 2017 Category: Neurology Source Type: research

Characteristics and Outcomes of Vertebrobasilar Artery Dissection with Accompanied Atherosclerosis
Conclusion: VBD-related PCS with and without accompanied atherosclerosis had different manifestations and should be regarded as distinct arterial diseases.Cerebrovasc Dis Extra 2017;7:165 –172
Source: Cerebrovascular Diseases Extra - October 17, 2017 Category: Neurology Source Type: research

Efficacy and Safety of Novel Oral Anticoagulants in Patients with Cervical Artery Dissections
We report on the use, safety, and efficacy of NOACs in the treatment of CAD. Methods: We retrospectively identified patients diagnosed with CAD at a single academic center between January 2010 and August 2013. Patients were categorized by their antithrombotic treatment at hospital discharge with a NOAC (dabigatran, rivaroxaban, or apixaban), traditional anticoagulant (AC: warfarin or treatment dose low-molecular weight heparin), or antiplatelet agent (AP: aspirin, clopidogrel, or aspirin/extended-release dypyridamole). Using appropriate tests, we compared the baseline medical history, presenting clinical symptoms and initi...
Source: Cerebrovascular Diseases - November 12, 2014 Category: Neurology Source Type: research

Spontaneous dissection of the bilateral internal carotid and vertebral arteries: A rationale for endovascular management
Spontaneous cervical-artery-dissection (sCAD) is a common cause of stroke in young patients. The incidence of concurrent sCAD of more than one neck artery ranges between 10 and 28% [1]. Multi-vessel sCAD is associated with a higher risk of intracranial hemorrhage as well as a higher risk of recurrent stroke or TIA [1]. Postpartum CAD accounts for 6% of spontaneous CAD in women under 50years of age [2]. Medical management is the primary treatment approach, while the role of endovascular intervention remains unclear.
Source: Journal of the Neurological Sciences - February 9, 2015 Category: Neurology Authors: Nitin Goyal, Shailesh Male, Vinodh T. Doss, Adam Arthur, Lucas Elijovich Tags: Letter to the Editor Source Type: research

Articles Antiplatelet treatment compared with anticoagulation treatment for cervical artery dissection (CADISS): a randomised trial
We found no difference in efficacy of antiplatelet and anticoagulant drugs at preventing stroke and death in patients with symptomatic carotid and vertebral artery dissection but stroke was rare in both groups, and much rarer than reported in some observational studies. Diagnosis of dissection was not confirmed after review in many cases, suggesting that radiographic criteria are not always correctly applied in routine clinical practice.
Source: Lancet Neurology - February 12, 2015 Category: Neurology Authors: The CADISS trial investigators Tags: Articles Source Type: research

NEWS FROM THE INTERNATIONAL STROKE CONFERENCE: Anti-Clotting Strategies Work to Prevent Stroke in Cervical Dissection Cases
No abstract available
Source: Neurology Today - March 19, 2015 Category: Neurology Tags: Features Source Type: research

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