[Comment] CADISS: a feasibility trial that answered its question

Anticoagulation after ischaemic stroke was a topic of major controversy for decades until a series of randomised clinical trials consistently showed no net benefit of heparin or warfarin compared with aspirin.1,2 Any reduction in the risk of recurrent ischaemic stroke was offset by an increase in risk of intracerebral haemorrhages. One cause of stroke for which the effect of anticoagulation remains unclear is cervical artery dissection. The classic dogma was that a tear in the intima leads to formation of a fibrin-rich thrombus and poses a very high risk of artery-to-artery embolism or occlusion, making early anticoagulation the treatment of choice.
Source: Lancet Neurology - Category: Neurology Authors: Tags: Comment Source Type: research