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Specialty: Infectious Diseases

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Total 484 results found since Jan 2013.

A cinematic approach to drug resistance
(Harvard Medical School) In a creative stroke inspired by Hollywood wizardry, scientists from Harvard Medical School and Technion-Israel Institute of Technology have designed a simple way to observe how bacteria move as they become impervious to drugs.
Source: EurekAlert! - Infectious and Emerging Diseases - September 8, 2016 Category: Infectious Diseases Source Type: news

Raising the curtain on cerebral malaria's deadly agents
(NIH/National Institute of Neurological Disorders and Stroke) Using state-of-the-art brain imaging technology, scientists at the National Institutes of Health filmed what happens in the brains of mice that developed cerebral malaria (CM). The results, published in PLOS Pathogens, reveal the processes that lead to fatal outcomes of the disease and suggest an antibody therapy that may treat it.
Source: EurekAlert! - Infectious and Emerging Diseases - December 6, 2016 Category: Infectious Diseases Source Type: news

HIV patients have nearly twice the heart attack risk
(Northwestern University) Current methods to predict the risk of heart attack and stroke vastly underestimate the risk in individuals with HIV, which is nearly double that of the general population, reports a new study. The higher risk exists even when virus is undetectable in blood because of antiretroviral drugs. Accurately predicting risk is vital for preventive treatment.
Source: EurekAlert! - Infectious and Emerging Diseases - December 21, 2016 Category: Infectious Diseases Source Type: news

Giant cell arteritis
(GCA), otherwise known as temporal arteritis, is a granulomatous inflammation of medium to large-sized vessels. It occurs mostly in elderly patients over the age of 70 although cases have been reported in patients as young as 50. It is a potentially sight threatening emergency and its recognition is crucial due to its devastating sequelae. Vision loss is often severe, and fellow eye involvement occurs within weeks or days if untreated. In addition, failure to rule out this condition can lead to cardiovascular complications including myocardial infarction and stroke.
Source: Disease a Month - December 29, 2016 Category: Infectious Diseases Authors: Hyeon Jeong Cho, Justin Bloomberg, Jeffrey Nichols Source Type: research

Fatal Neisseria macacae infective endocarditis: first report
We present here the first case ofN. macacae infective endocarditis in a 65-year-old man with a native aortic valve infection complicated by a peri-aortic abscess. N. macacae was isolated from blood culture and was found on the cardiac valve using 16S rDNA detection. Despite an appropriate antibiotic therapy, and aortic homograft replacement, and mitral repair, the patient died 4  days after surgery from a massive hemorrhagic stroke.
Source: Infection - January 27, 2017 Category: Infectious Diseases Source Type: research

Relationship Between HIV Infection, Antiretroviral Therapy, Inflammatory Markers, and Cerebrovascular Endothelial Function Among Adults in Urban China
Conclusions: Cerebrovascular endothelial dysfunction associated with HIV infection may be most relevant for individuals with less traditional vascular risk, such as those with lower cholesterol. Further study of the impact of ART on cerebrovascular endothelial function is warranted to aid with ART selection in individuals at high cerebrovascular risk.
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - February 14, 2017 Category: Infectious Diseases Tags: Clinical Science Source Type: research

Performance of the Pooled Cohort Atherosclerotic Cardiovascular Disease Risk Score in Hepatitis C Virus ‐infected Persons
This article is protected by copyright. All rights reserved.
Source: Journal of Viral Hepatitis - March 7, 2017 Category: Infectious Diseases Authors: Kara W. Chew, Debika Bhattacharya, Tamara B. Horwich, Peng Yan, Kathleen A. McGinnis, Chi ‐hong Tseng, Matthew S. Freiberg, Judith S. Currier, Adeel A. Butt Tags: Original Paper Source Type: research

HIV/HCV Co ‐infection and the risk of Cardiovascular Disease: A Meta‐analysis
In conclusion, individuals with HIV/HCV coinfection had an increased risk compared to those with HIV monoinfection. More research is needed to further examine the nature of this association, and response to traditional risk reductive therapies. This article is protected by copyright. All rights reserved.
Source: Journal of Viral Hepatitis - May 1, 2017 Category: Infectious Diseases Authors: Olatokunbo Osibogun, Oluseye Ogunmoroti, Erin D. Michos, Erica S. Spatz, Babatunde Olubajo, Khurram Nasir, Purnima Madhivanan, Wasim Maziak Tags: Original Paper Source Type: research

Hypertension in HIV: Management and Treatment.
Abstract Hypertension is among the leading risk factors for cardiovascular disease and accounts for 6% of adult deaths worldwide. It is estimated that in 2013, hypertension was responsible for at least 45% of deaths due to heart disease and 51% of deaths due to stroke. Accordingly, management of hypertension and its long-term complications in HIV-infected subjects is a significant component of routine care. The choice of an effective anti-hypertensive therapy in HIV-infected patients is important and must be made carefully in order to prevent cardiovascular mortality and morbidity in these patients. PMID: 285...
Source: AIDS Reviews - May 23, 2017 Category: Infectious Diseases Authors: Ucciferri C, Falasca K, Vecchiet J Tags: AIDS Rev Source Type: research

HIV/HCV coinfection and the risk of cardiovascular disease: A meta ‐analysis
In conclusion, individuals with HIV/HCV coinfection had an increased CVD risk compared to those with HIV monoinfection. More research is needed to further examine the nature of this association, and response to traditional risk‐reduction therapies.
Source: Journal of Viral Hepatitis - June 23, 2017 Category: Infectious Diseases Authors: O. Osibogun, O. Ogunmoroti, E. D. Michos, E. S. Spatz, B. Olubajo, K. Nasir, P. Madhivanan, W. Maziak Tags: ORIGINAL ARTICLE Source Type: research

Impact of aging on neurocognitive performance in previously antiretroviral-naive HIV-infected individuals on their first suppressive regimen
Conclusion: Despite continued virologic suppression and neurocognitive improvement in the cohort as a whole, older individuals were more likely to have neurocognitive impairment than younger individuals.
Source: AIDS - June 30, 2017 Category: Infectious Diseases Tags: Clinical Science Source Type: research

Use of direct oral anticoagulants for treatment of atrial fibrillation in patients with HIV: a review
Purpose of review: Atrial fibrillation is increasingly common in the ageing population. Patients with atrial fibrillation and HIV have a higher stroke risk, with guidelines recommending anticoagulation in the majority. Whilst anticoagulation options have diversified in the last decade for the general population, there is limited evidence for the safety and efficacy of these medications when used concurrently with antiretroviral therapy. We review the potential for patients with HIV on antiretroviral therapy to have direct-acting oral anticoagulations (DOACs). Recent findings: Several case reports have been published in th...
Source: Current Opinion in HIV and AIDS - October 7, 2017 Category: Infectious Diseases Tags: CARDIOVASCULAR DISEASE IN HIV INFECTED PERSONS: Edited by Franck Boccara and Cameron J. Holloway Source Type: research

Cardiovascular disease risk among women living with HIV in North America and Europe
Purpose of review: To examine the epidemiology and mechanistic underpinnings of heightened cardiovascular disease (CVD) risk among women living with HIV (WLHIV) in North America and Europe. Recent findings: WLHIV in North America and Europe exhibit high CVD incidence rates, which are at par with those of compatriot men living with HIV. Compared with uninfected women, WLHIV in these regions face a 2–4-fold increased relative risk for myocardial infarction, stroke, and heart failure. HIV-associated CVD risk is fuelled by a negative synergy of traditional cardiometabolic risk factors and heightened systemic immune activati...
Source: Current Opinion in HIV and AIDS - October 7, 2017 Category: Infectious Diseases Tags: CARDIOVASCULAR DISEASE IN HIV INFECTED PERSONS: Edited by Franck Boccara and Cameron J. Holloway Source Type: research

HIV patients at greater risk of both heart and kidney disease
(University of Adelaide) HIV patients and their doctors are urged to be more aware of the additional health risks associated with treated HIV infection. This follows new research that shows HIV patients at high risk for a heart attack or stroke are also at substantially greater risk for chronic kidney disease and vice versa.
Source: EurekAlert! - Infectious and Emerging Diseases - November 7, 2017 Category: Infectious Diseases Source Type: news

Liberia:Aids, NCDs, and the ABCs of Organizing
[New Dawn] Geneva -Non-communicable diseases (NCDs), like heart disease, stroke, cancer, diabetes, and chronic lung disease, are responsible for 70% of all deaths. There is incontrovertible evidence that tobacco use, inactivity, unhealthy diets, and excessive alcohol consumption increase the odds of dying prematurely from an NCD.
Source: AllAfrica News: HIV-Aids and STDs - December 13, 2017 Category: Infectious Diseases Source Type: news