Performance of the Pooled Cohort Atherosclerotic Cardiovascular Disease Risk Score in Hepatitis C Virus ‐infected Persons

We examined the performance of the ASCVD risk score in HCV‐infected persons, using the national Electronically Retrieved Cohort of HCV Infected Veterans (ERCHIVES) to derive a cohort of HCV‐infected and uninfected subjects without baseline ASCVD, hepatitis B, or HIV infection, and with low‐density lipoprotein cholesterol level
Source: Journal of Viral Hepatitis - Category: Infectious Diseases Authors: Tags: Original Paper Source Type: research

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CONCLUSION: Despite some limitations, the higher number of quality-adjusted life years gained vs rehab and the high probability of reaching a cost-utility ratio lower than the Italian informal acceptability range (€25,000-40,000) make rehab/aboBoNT-A a cost-effective healthcare programme for treating patients with post-stroke spasticity in Italy. PMID: 31820010 [PubMed - as supplied by publisher]
Source: Journal of Rehabilitation Medicine - Category: Rehabilitation Tags: J Rehabil Med Source Type: research
Publication date: Available online 11 December 2019Source: Journal of Functional FoodsAuthor(s): Lanlan Yuan, Fan Zhang, Shuo Jia, Jianhua Xie, Mingyue ShenAbstractPhytosterols have been shown to be effective in reducing blood cholesterol by suppressing intestinal cholesterol absorption in both humans and animals. In present study, the inhibition of cholesterol absorption in Caco-2 cells by ergosterol, ergosterol acetate, β-sitosterol, stigmasterol, campesterol and stellasterol were systematically assessed. Results showed that the phytosterols produced cholesterol-lowering effect in Caco-2 cells. This effect was large...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
Researchers analyzed 11 years of data from more than 65,000 people, ages 40-79, living in the American Southeast. More than two-thirds of the participants were black, and about two-thirds were at high risk for heart attack or stroke at the start of the study period.
Source: WebMD Health - Category: Consumer Health News Source Type: news
ConclusionsPost-stroke delirium may frequently go undetected by the CAM-ICU, even in the setting of fluctuating consciousness.
Source: Journal of Critical Care - Category: Gastroenterology Source Type: research
ConclusionsCurcumin improved insulin resistance, lipid profile and systemic inflammation by reducing HOMA-IR, TG, TG/HDL ratio and hs-CRP levels in β-thalassemia major patients. Curcumin may be useful as an adjuvant therapy for attenuation of the metabolic complications in these patients.
Source: Journal of Herbal Medicine - Category: Complementary Medicine Source Type: research
Publication date: Available online 11 December 2019Source: American Heart JournalAuthor(s): Geoffrey Lau, Maria Koh, Peter A. Kavsak, Michael J. Schull, David W.J. Armstrong, Jacob A. Udell, Peter C. Austin, Xuesong Wang, Dennis T. KoABSTRACTBackgroundHigh-sensitivity cardiac troponin (hs-cTn) assays enhance detection of lower circulating troponin concentrations, but the impact on outcomes in clinical practice is unclear. Our objective was to compare outcomes of chest pain patients discharged from emergency departments (EDs) using hs-cTn and conventional troponin (cTn) assays.MethodsWe conducted an observational study of c...
Source: American Heart Journal - Category: Cardiology Source Type: research
Publication date: 10 December 2019Source: Cell Reports, Volume 29, Issue 11Author(s): Guangyun Tan, Zhaohong Yi, Hongxiao Song, Fengchao Xu, Feng Li, Roghiyh Aliyari, Hong Zhang, Peishuang Du, Yanhua Ding, Junqi Niu, Xiaosong Wang, Lishan Su, F. Xiao-Feng Qin, Genhong ChengSummaryTo understand the molecular mechanisms that mediate the anti-hepatitis B virus (HBV) effect of interferon (IFN) therapy, we conduct high-throughput bimolecular fluorescence complementation screening to identify potential physical interactions between the HBx protein and 145 IFN-stimulated genes (ISGs). Seven HBx-interacting ISGs have con...
Source: Cell Reports - Category: Cytology Source Type: research
Publication date: Available online 10 December 2019Source: Journal of Clinical NeuroscienceAuthor(s): David I. Bass, Melanie Walker, Louis J. Kim, Michael R. LevittAbstractIatrogenic dissection of the internal carotid artery is a well-known complication that can occur during mechanical thrombectomy for acute stroke. The vast majority of these injuries are limited to the cervical segment, and only in exceptional circumstances do they require surgical intervention. In the present case, extension of the lesion into the petrous segment of the carotid artery resulted in an acute neurologic decline necessitating emergent endovas...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
Publication date: Available online 10 December 2019Source: Journal of Clinical NeuroscienceAuthor(s): Junya Aoki, Kentaro Suzuki, Satoshi Suda, Seiji Okubo, Masahiro Mishina, Kazumi KimuraAbstractBackgroundSince acute fluid-attenuated inversion recovery vascular hyperintensity (FVH) is indicative of disordered blood flow, FVH is considered a marker of acute major arterial occlusion. Conversely, the role of the absence of FVH (negative-FVH) remains unknown.MethodsConsecutive stroke patients were studied via magnetic resonance angiography, within 24 h of onset and major arterial occlusion. All patients were examined usi...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
AbstractLarge volumes of raw data are created from the digital world every day. Acquiring useful information from these data is challenging, and it turned into a prime zone of momentum explore. More research is done in this direction. Further, in disease diagnosis, many uncertainties are involved in the information system. To handle such uncertainties, intelligent techniques are employed. In this paper, we present an integrated scheme for heart disease diagnosis. The proposed model integrates cuckoo search and rough set for inferencing decision rules. At the underlying phase, we employ a cuckoo search to discover the main ...
Source: Journal of Medical Systems - Category: Information Technology Source Type: research
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