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Specialty: Gastroenterology

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Total 421 results found since Jan 2013.

Percutaneous Endoscopic Gastrostomy Tube Insertion in Neurodegenerative Disease: A Retrospective Study and Literature Review.
Conclusions: This study highlights the relatively high risk of PEG in patients with neurodegenerative disease. We present points for consideration to improve outcome in this particularly vulnerable group of patients. PMID: 27737522 [PubMed - as supplied by publisher]
Source: Clinical Endoscopy - October 15, 2016 Category: Gastroenterology Tags: Clin Endosc Source Type: research

Major Gastrointestinal Bleeding is Often Caused by Occult Malignancy in Patients Receiving Warfarin or Dabigatran to Prevent Stroke and Systemic Embolism From Atrial Fibrillation
Gastrointestinal (GI) bleeding in patients receiving anticoagulation agents can be caused by occult malignancies. We investigated the proportions and features of major GI bleeding (MGIB) events related to occult GI cancers in patients receiving anticoagulation therapy.
Source: Clinical Gastroenterology and Hepatology - October 16, 2016 Category: Gastroenterology Authors: Kathryn F. Flack, Jay Desai, Jennifer M. Kolb, Prapti Chatterjee, Lars C. Wallentin, Michael Ezekowitz, Salim Yusuf, Stuart Connolly, Paul Reilly, Martina Brueckmann, John Ilgenfritz, James Aisenberg Source Type: research

Major Gastrointestinal Bleeding Often Is Caused by Occult Malignancy in Patients Receiving Warfarin or Dabigatran to Prevent Stroke and Systemic Embolism From Atrial Fibrillation
Gastrointestinal (GI) bleeding in patients receiving anticoagulation agents can be caused by occult malignancies. We investigated the proportions and features of major GI bleeding (MGIB) events related to occult GI cancers in patients receiving anticoagulation therapy.
Source: Clinical Gastroenterology and Hepatology - October 16, 2016 Category: Gastroenterology Authors: Kathryn F. Flack, Jay Desai, Jennifer M. Kolb, Prapti Chatterjee, Lars C. Wallentin, Michael Ezekowitz, Salim Yusuf, Stuart Connolly, Paul Reilly, Martina Brueckmann, John Ilgenfritz, James Aisenberg Source Type: research

Diabetics on Narcotics Are Less Likely to Achieve Excellent Bowel Preparation Than Are Patients with Either Condition
ConclusionConcomitant narcotic use and diabetes have a compounding effect on the quality of bowel preparation prior to colonoscopy.
Source: Digestive Diseases and Sciences - December 28, 2016 Category: Gastroenterology Source Type: research

Role of Endoscopic Gastroplasty Techniques in the Management of Obesity.
Authors: Jung Y Abstract Health and wellness represent a major global concern. Trends such as a lack of exercise and excessive consumption of calories are major causes of the rapid increase in obesity worldwide. Obesity should be controlled because it can result in other illnesses, such as diabetes, high blood pressure, high cholesterol, coronary artery disease, stroke, breathing disorders, or cancer. However, many people have difficulty in managing obesity through exercise, dietary control, behavioral modifications, and drug therapy. Bariatric surgery is not commonly used due to a variety of complications, even th...
Source: Clinical Endoscopy - February 5, 2017 Category: Gastroenterology Tags: Clin Endosc Source Type: research

Gastrointestinal Bleeding and Direct Oral Anticoagulants Amongst Patients With Atrial Fibrillation in the “Real World”
The pivotal aim of oral anticoagulation in atrial fibrillation (AF) is prevention of AF-related thromboembolic strokes. The vitamin K antagonists (eg, warfarin) have been the standard of care for many years, reducing both stroke and mortality rates by 64% and 26% respectively, compared with placebo/control.1 Approval and market release of direct oral anticoagulants (DOACs; also referred to as non-vitamin K antagonist oral anticoagulants2), such as dabigatran, rivaroxaban, apixaban, and edoxaban, have changed the landscape of thromboprophylaxis substantially.
Source: Gastroenterology - February 28, 2017 Category: Gastroenterology Authors: Micha ł Mazurek, Gregory Y.H. Lip Tags: Editorial Source Type: research

Gastrointestinal Bleeding With Oral Anticoagulation: Understanding the Scope of the Problem
Systemic anticoagulation with vitamin K antagonists or direct-acting oral anticoagulants (DOACs) remains the mainstay of therapy to attenuate the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation (NVAF). Given more predictable pharmacology, use of fixed-dose regimens, and lack of need for routine drug monitoring, DOACs have enjoyed relatively high uptake and quickly have become integrated into clinical practice.1 Although these agents generally have a favorable index of safety in comparison with warfarin with a lower risk of intracranial hemorrhage, rates of major gastrointestinal (GI) b...
Source: Clinical Gastroenterology and Hepatology - January 13, 2017 Category: Gastroenterology Authors: Muthiah Vaduganathan, Deepak L. Bhatt Tags: Editorial Source Type: research

Assessment of macro- and micro-oxygenation parameters during fractional fluid infusion: A pilot study
Conclusions Maximal fluid infusion improves macro- and micro-circulatory oxygenation parameters. For VO2-Responders, only ScVO2 and cerebral rSO2 could serve as markers of tissue hypoxia.
Source: Journal of Critical Care - March 31, 2017 Category: Gastroenterology Source Type: research

Haemodynamic changes with paracetamol in critically-ill children
Conclusion There is a significant but modest reduction in blood pressure post-paracetamol in critically-ill children. This is likely related to a change in systemic vascular resistance.
Source: Journal of Critical Care - April 2, 2017 Category: Gastroenterology Source Type: research

Gastrointestinal bleeding in patients on novel oral anticoagulants: Risk, prevention and management.
Abstract Novel oral anticoagulants (NOACs), which include direct thrombin inhibitor (dabigatran) and direct factor Xa inhibitors (rivaroxaban, apixaban and edoxaban), are gaining popularity in the prevention of embolic stroke in non-valvular atrial fibrillation as well as in the prevention and treatment of venous thromboembolism. However, similar to traditional anticoagulants, NOACs have the side effects of bleeding, including gastrointestinal bleeding (GIB). Results from both randomized clinical trials and observations studies suggest that high-dose dabigatran (150 mg b.i.d), rivaroxaban and high-dose edoxaban (6...
Source: World Journal of Gastroenterology : WJG - March 21, 2017 Category: Gastroenterology Authors: Cheung KS, Leung WK Tags: World J Gastroenterol Source Type: research

Impact of postoperative complications on readmission and long-term survival in patients following surgery for colorectal cancer
ConclusionsOverall combined morbidity as assessed by the CCI leads to more frequent readmission, and is associated with poorer long-term survival after surgery for CRC.
Source: International Journal of Colorectal Disease - April 14, 2017 Category: Gastroenterology Source Type: research

The impact of minor blood transfusion on the outcome after coronary artery bypass grafting
Conclusion Minor perioperative bleeding and subsequent transfusion of 1–2 RBC units did not affect the risk of early death, but increased the risk of other major adverse events. Minimizing perioperative bleeding and prevention of even low-volume RBC transfusion may improve the outcome after CABG.
Source: Journal of Critical Care - April 23, 2017 Category: Gastroenterology Source Type: research

Characterization of Cardiac Dysfunction by Echocardiography in Early Severe Acute Pancreatitis
Conclusions: Two thirds of patients with early SAP and hypotension had cardiac dysfunction, which was most commonly diastolic dysfunction. A better understanding of the nature of cardiac dysfunction in this setting may allow more accurate diagnosis, prognostication, and management.
Source: Pancreas - April 25, 2017 Category: Gastroenterology Tags: Original Articles Source Type: research

Risk of Gastrointestinal Bleeding in Patients Taking Non-vitamin K Antagonist Oral Anticoagulants: a Systematic Review and Meta-analysis
Non-vitamin K antagonist oral anticoagulants (NOACs) are convenient and effective in prevention and treatment of venous thromboembolism and prevention of stroke in patients with atrial fibrillation. However, these drugs have been associated with increased risk of gastrointestinal (GI) bleeding. We conducted a systematic review and meta-analysis to determine the risk of GI bleeding in patients receiving these drugs.
Source: Clinical Gastroenterology and Hepatology - April 27, 2017 Category: Gastroenterology Authors: Corey S. Miller, Alastair Dorreen, Myriam Martel, Thao Huynh, Alan N. Barkun Source Type: research

Mo1086 Severity of Gastrointestinal Bleeding in Patients Treated With Direct-Acting Oral Anticoagulants (Doacs)
Direct-acting oral anticoagulants (DOACs), which have recently been approved for stroke prevention in non-valvular atrial fibrillation and treatment of venous thromboembolism, have become increasingly preferred over warfarin given their predictable pharmacodynamics and lack of required monitoring. DOACs have been shown to be associated with an increased frequency of gastrointestinal bleeding (GIB) compared to warfarin, but the severity of GIB in these patients is poorly understood.
Source: Gastrointestinal Endoscopy - April 28, 2017 Category: Gastroenterology Authors: Mark M. Brodie, Tyler Smith, Jill Newman, Don C. Rockey Tags: Monday – ASGE poster Source Type: research