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Total 550 results found since Jan 2013.

Retinal Microvascular Abnormalities as Surrogate Markers of Cerebrovascular Ischemic Disease: A Meta-Analysis
To determine the predictive value of retinal microvascular abnormalities for cerebrovascular ischemic diseases (CVDs), we aimed to investigate the quantitative association between retinal microvascular changes and CVD subcategories: white matter hyperintensities (WMHIs), lacunar infarcts (LIs), and cerebral infarctions (CIs).
Source: Journal of Stroke and Cerebrovascular Diseases - March 20, 2018 Category: Neurology Authors: Oana M. Dumitrascu, Bart M. Demaerschalk, Cristina Valencia Sanchez, Diana Almader-Douglas, Cumara B. O'Carroll, Maria I. Aguilar, Patrick D. Lyden, Gyanendra Kumar Source Type: research

Management of central retinal artery occlusion following successful hyperbaric oxygen therapy: case report.
Conclusion: Recovery of vision during initial HBO₂ treatment indicated that this patient's retina had not yet suffered irreversible ischemic damage at that point in time. CRAO patients with a good result from initial HBO₂ treatment should be admitted to a stroke center and should have their visual status monitored hourly. Should vision loss recur, aggressive use of intermittent 100% normobaric and hyperbaric oxygen is indicated to preserve retinal function until central retinal artery recanalization occurs. An evidence-based management plan for such patients is presented. PMID: 29571239 [PubMed - in process]
Source: Undersea and Hyperbaric Medicine - January 1, 2018 Category: Sports Medicine Authors: Butler FK, Hagan C, Van Hoesen K, Murphy-Lavoie H Tags: Undersea Hyperb Med Source Type: research

Remember the retina: retinal disorders presenting to neurologists.
This article focuses on how a general neurologist can identify retinal problems from the clinical assessment and how to proceed with initial investigations. The following cases were all referred to a consultant neurologist (GTP) from ophthalmology services as optic neuropathies or other neurological disorders. Part A of the summary describes the presentation and findings in the neurology clinic; part B describes the subsequent specialist assessment in the neuro-ophthalmology/eye clinic. PMID: 29572353 [PubMed - as supplied by publisher]
Source: Practical Neurology - March 23, 2018 Category: Neurology Authors: Khaleeli Z, Tucker WR, Del Porto L, Virgo JD, Plant GT Tags: Pract Neurol Source Type: research

Carotid ergotism with retinal ischemia
Ergot poisoning was first described more than 2,000 years ago with the consumption of food contaminated with mycotoxins. It acquired special importance during the 20th century because of an excessive consumption of ergot pharmaceuticals as symptomatic treatment of migraine.1,2
Source: Neurology Clinical Practice - April 9, 2018 Category: Neurology Authors: Altuna-Azkargorta, M., Herrera-Isasi, M., Zandio-Amorena, B., Bacaicoa-Saralegui, M. C. Tags: Migraine, All Clinical Neurology, All Cerebrovascular disease/Stroke, Critical care Case Source Type: research

Transient monocular blindness: Vascular causes and differential diagnoses.
Authors: Bidot S, Biotti D Abstract Transient monocular blindness is an acute episode of ischemic origin in which one eye has profound visual loss, followed by full recovery within one hour. Transient monocular blindness most often occurs in the setting of retinal ischemia secondary to carotid embolism, but other mechanisms have been reported, including thrombosis (most often in the setting of giant cell arteritis), hemodynamic disorders (secondary to severe carotid stenosis), or vasospasm. Transient monocular blindness is considered a transient ischemic attack originating in the carotid arteries, and must be manag...
Source: Journal Francais d Ophtalmologie - April 22, 2018 Category: Opthalmology Tags: J Fr Ophtalmol Source Type: research

Retinal Abnormalities Predictor of Some Types of Stroke
(MedPage Today) -- Retinal imaging may offer noninvasive tool to determine pathogenesis of cerebral small vessel disease
Source: MedPage Today Cardiovascular - April 24, 2018 Category: Cardiology Source Type: news

Transient monocular blindness: Vascular causes and differential diagnoses.
Authors: Bidot S, Biotti D Abstract Transient monocular blindness is an acute episode of ischemic origin in which one eye has profound visual loss, followed by full recovery within one hour. Transient monocular blindness most often occurs in the setting of retinal ischemia secondary to carotid embolism, but other mechanisms have been reported, including thrombosis (most often in the setting of giant cell arteritis), hemodynamic disorders (secondary to severe carotid stenosis) or vasospasm. Transient monocular blindness is considered a transient ischemic attack originating in the carotid arteries and must benefit fr...
Source: Journal Francais d Ophtalmologie - May 20, 2018 Category: Opthalmology Tags: J Fr Ophtalmol Source Type: research

Clinical presentation of multiple cerebral emboli and central retinal artery occlusion (CRAO) as signs of cardiac myxoma
We present a patient whose history of cerebral emboli and central retinal artery occlusion (CRAO) led to a diagnosis of cardiac myxoma.Neuroimaging studies showed multiple infarcts in the region of the left middle and anterior cerebral arteries. Ophthalmic examination showed gross retinal pallor compatible with left central retinal artery occlusion (CRAO).The etiology of stroke was investigated by performing trans-thoracic echocardiography, which showed a mass in the left atrium compatible with cardiac myxoma. Complete removal of the cardiac tumor was performed by open-heart surgery.Fortunately, after a period of rehabilit...
Source: Saudi Journal of Ophthalmology - July 5, 2018 Category: Opthalmology Source Type: research

Clinical Efficacy of Platelet-Rich Plasma in the Treatment of Neurotrophic Corneal Ulcer.
Conclusions: Autologous platelet-rich plasma is a blood-based product which seems efficient in the treatment of neurotrophic keratopathy. PMID: 30026985 [PubMed]
Source: Journal of Ophthalmology - July 22, 2018 Category: Opthalmology Tags: J Ophthalmol Source Type: research

Is Management of Central Retinal Artery Occlusion the Next Frontier in Cerebrovascular Diseases?
Central retinal artery occlusion (CRAO) is a medical emergency that, if not treated, may result in irreversible loss of vision. It continues to be an important cause for acute painless loss of vision. Amaurosis fugax or “transient CRAO” has long been considered an equivalent of transient cerebral ischemic event. Animal models, in addition to data from retrospective and randomized clinical studies, provide valuable insights into the time interval for irreversible retinal ischemia. Subset analyses from 2 large st udies of patients with CRAO show benefit from treatment with thrombolysis within 6 hours from symptoms onset.
Source: Journal of Stroke and Cerebrovascular Diseases - July 27, 2018 Category: Neurology Authors: Kaustubh Limaye, Michael Wall, Sami Uwaydat, Sheharayar Ali, Amir Shaban, Sami Al Kasab, Harold Adams Source Type: research

A Review on the Extraction of Quantitative Retinal Microvascular Image Feature.
Authors: Kipli K, Hoque ME, Lim LT, Mahmood MH, Sahari SK, Sapawi R, Rajaee N, Joseph A Abstract Digital image processing is one of the most widely used computer vision technologies in biomedical engineering. In the present modern ophthalmological practice, biomarkers analysis through digital fundus image processing analysis greatly contributes to vision science. This further facilitates developments in medical imaging, enabling this robust technology to attain extensive scopes in biomedical engineering platform. Various diagnostic techniques are used to analyze retinal microvasculature image to enable geometric fe...
Source: Computational and Mathematical Methods in Medicine - August 3, 2018 Category: Statistics Tags: Comput Math Methods Med Source Type: research

Safety of 5914 intravitreal ziv-aflibercept injections.
CONCLUSION: This constitutes the largest pooled safety report on IVZ use and includes patients from 14 centres distributed across the globe. It shows that IVZ has an acceptable ocular and systemic safety profile with incidences of adverse events similar to those of other vascular endothelial growth factor inhibitory drugs. The analysis supports the continued use of IVZ in various retinal disorders. PMID: 30099379 [PubMed - as supplied by publisher]
Source: The British Journal of Ophthalmology - August 11, 2018 Category: Opthalmology Authors: Singh SR, Stewart MW, Chattannavar G, Ashraf M, Souka A, ElDardeery M, Wadhwa N, Sarvaiya C, Mansour AM, Marashi A, Ramchandani S, Braimah IZ, Jabbarpoor Bonyadi MH, Ramezani A, Soheilian M, de Oliveira Dias JR, de Andrade GC, Maia A, Rodrigues EB, Farah Tags: Br J Ophthalmol Source Type: research

Fluctuations of Nutrition-Associated Markers After Decompressive Hemicraniectomy in Middle Cerebral Artery Occlusion Patients.
Authors: Kutsuna N, Makita K, Goto K, Hirayama K, Kido G, Kagawa Y Abstract Cerebral infarction (CI) caused by middle cerebral artery occlusion exhibits a very high mortality rate. To reduce this rate, a decompressive hemicraniectomy (DHC) is performed clinically based on several randomized trials. In ischemic stroke, a state of malnutrition leads to poor outcomes. However, little evidence is available on nutrition state in the acute phase after DHC. This preliminary study focuses on serum markers, especially dynamic or static nutrition-associated markers including prealbumin, transferrin, retinol binding protein (...
Source: Advances in Experimental Medicine and Biology - September 6, 2018 Category: Research Tags: Adv Exp Med Biol Source Type: research

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